• 대한융합한의학회지
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• 제5권2호
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• pp.11-16
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• 2023

Objectives: The purpose of this study was to investigate the anti-obesity effects of the aqueous extract of Schizandra chinensis (SC) in menopausal mice. Methods: To induce menopausal obesity, female mice were ovariectomized (OVX) and fed a high-fat diet (HFD; 60% fat, 28% carbohydrates, 14% protein) for 12 weeks. The mice were divided into 6 groups (n = 8): NOR (sham-operated and vehicle-treated), HFD+OVX (vehicle-treated), E2 (17-beta estradiol 50 ㎍/kg-treated), SC1 (1 mg/kg SC-treated), SC10 (10 mg/kg SC-treated), and SC100 (100 mg/kg SC-treated). Samples were orally administered for 6 weeks, after which all experimental mice were sacrificed. Body weight, feeding efficiency, white adipose tissue weight, adipocyte diameter, and fat vacuoles in liver were analyzed. Results: By treating with SC extract, the body weight and feeding efficiency of mice were significantly decreased. The weight of visceral fat tissues was decreased in the SC10 and SC100 groups. Histopathology showed that fat cell diameters of white adipose tissue were also decreased in the SC10 and SC100 groups. Additionally, SC extract regenerated the hepatocyte damage and decreased the size and number of follicular adipocytes Conclusion: In summary, these results suggest that SC has inhibitory effects against menopausal obesity. Schizandra chinensis may be a potential alternative for obesity among female menopausal diseases.

• 한국기계가공학회지
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• 제8권4호
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• pp.136-142
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• 2009

The vehicle's light-weight technology is divided into optimization of structure geometric and material. Structure geometric optimization and improvement of materials has examined to be power-train and maintenance on the severe condition. The core technology of Special vehicle's light-weight is constitute by Drop box, Axle and Final reduction gear. Technology and product of the parts is high to overseas and import dependency. We will want to examine the possibility of light-weight for the Axle Case and Drop box-connections. In this research, conventional design of excess weight will inhibit the mobility and fuel efficiency. Through the improvement of Axle material, we saw the possibility reducing weight. If you use the results of these studies, it will be available to domestic production technology and reducing weight of RV car, Dump truck, Track crain, etc.

• 인간식물환경학회지
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• 제22권6호
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• pp.551-561
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• 2019

This study was conducted to find out differences in the removal efficiency of particulate matter (PM) depending on the type of plants and the morphological characteristics of leaves. A total of 12 plants were used, with three plants selected for each type of leaves (big leaf, small leaf, compound leaf, needle leaf). We measured the removed amount of PM10 and PM2.5, the structure of the abaxial leaf surface, and the weight of the wax layer of each plant. Plants with the high removal efficiency of PM included Pachira aquatica Aubl., Ardisia crenata, and Dieffenbachia 'Marianne', and plants with the low removal efficiency included Nandina domestica Thunb, Schefflera arboricola, and Quercus dentata. The abaxial leaf surface having a high removal efficiency of PM had many large wrinkles, and the abaxial leaf surface having a medium removal efficiency was flat and smooth. On the other hand, there were many fine hairs on the abaxial leaf surface with a low removal efficiency. According to the plant leaf type, the PM10 removal efficiency of plants with needle leaves was about three times higher than that of other plants. In particular, the wax layer of conifers weighed 6-24 times higher than those of other plants. The stomata of conifers were evenly distributed on the adaxial and abaxial leaf surfaces; however, the stomata of Sciadopitys verticillata appeared in the form of papillae unlike general stomata. Therefore, the removal efficiency of PM varied depending on the macro-, and micro-morphological characteristics of plant leaves such as the structure of the abaxial leaf surface, and the weight of the wax layer. Based on this research, selecting plants that are effective in reducing PM in consideration of the plant type and leaf characteristics will improve indoor air quality and decrease exposure of PM to human body.

• Journal of Korean Biological Nursing Science
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• 제16권4호
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• pp.309-317
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• 2014

Purpose: The purpose of this study was to understand sleep circadian rhythm and sleep quality between normal-weight and obese group according to Body Mass Index to develop education and nursing intervention programs for the obese. Methods: This study involved 186 subjects who visited at S hospital obesity clinic, K province. They were divided into 2 groups: normal-weight group 91 and obese group 95. Data were collected from October 18th to November 12th in 2013. Data were analyzed with frequency, percentage, ${\chi}^2$-test, Mann-Whitney U test, ANCOVA, t-test and ANOVA with using SPSS version 20.0. Results: The results showed that morning type 1.1%, middle type 91.2% and evening type 7.7% of sleep circadian rhythm in normal-weight group and middle type 92.6% and evening type 7.4% of sleep circadian rhythm in obese group. There were statistically significant results on sleep quality with covariance sex and stress, sleep duration, habitual sleep efficiency and sleep disturbance between normal-weight and obese group. There were statistically significant results on sleep quality, sleep duration, habitual sleep efficiency and sleep disturbance in middle type of sleep circadian rhythm between normal-weight and obese group. Conclusion: Therefore, it is necessary to consider subject's sleep pattern to develop education and nursing intervention programs for the obese.

• 대한조선학회논문집
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• 제54권4호
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• pp.352-359
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• 2017

Because the Energy Efficiency Design Index(EEDI) came into effect in 2013, it is necessary to develop a new technology to overcome $CO_2$ emission regulations. In structural design viewpoint, lots of researches are carried out to develop eco-friendly and high fuel efficiency ships by weight reduction. By using the automated compartment arrangement system and automated structural design algorithm which were developed by the authors, new researches are performing to combine the above two systems. However, the effect of weight reduction was not significant because structural designs by using these systems for the midship part was carried out only focused on the minimum still water bending moment. In this paper, at first, good compartment arrangements which give the minimum still water bending moment and(or) shear force were chosen by using the automated compartment system. And then, influence of shear force on weight reduction was investigated by using the automated structural design algorithm considering longitudinal strength, local strength and shear strength of longitudinal members in cargo holds. Conclusively, it is necessary to consider the minimum still water bending moment and shear force simultaneously to reduce the weight of mid-sized bulk carrier. Also, good compartment arrangement which gives much more weight reduction compared with existing ship was proposed.

• 로봇학회논문지
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• 제13권2호
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• pp.86-91
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• 2018

This paper presents about design efforts of a human-sized quadruped robot leg for high energy efficiency, and verifications. One of the representative index of the energy efficiency is the Cost of Transport (COT), but increased in the energy or work done is not calculated in COT. In this reason, the input to the output energy efficiency should be also considered as a very important term. By designing the robot with customized motor housing, small rotational inertia, and low gear ratio to reduce friction, high energy efficiency was achieved. Squatting motion of one leg was performed and simulation results were compared to the experimental results for validation. The developed 50 kg robot can lift the weight up to 200 kg, and during squatting, it showed high energy efficiency. The robot showed 71% input to output energy efficiency in positive work. Peak current during squatting only appears to be 0.3 A.

• Structural Engineering and Mechanics
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• 제47권4호
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• pp.495-511
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• 2013

In this paper, a new efficient optimization algorithm called Teaching-Learning-Based Optimization (TLBO) is used for the least weight design of trusses with continuous design variables. The TLBO algorithm is based on the effect of the influence of a teacher on the output of learners in a class. Several truss structures are analyzed to show the efficiency of the TLBO algorithm and the results are compared with those reported in the literature. It is concluded that the TLBO algorithm presented in this study can be effectively used in the weight minimization of truss structures.

• PNF and Movement
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• 제16권2호
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• pp.179-185
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• 2018

Purpose: This study aimed to analyze the visual and spatial elements of the gait of a stroke patient who had diverse ankle weight loads applied, according to weight changes. Methods: The subject was a 57-year-old stroke patient diagnosed and hospitalized with a left intracerebral hemorrhage. A weight equivalent to 0%, 1%, and 2% of his body weight was applied to the area 5cm upward from the ankle using a Velcro strap. He was then trained on a treadmill, receiving a six-minute walk test to evaluate his gait ability. A gait analyzer was used to collect visual and spatial elements, such as gait distance, gait velocity, cadence, step length, stride length, and swing phase, according to a weight load equivalent to 0%, 1%, and 2% of his body weight. Results: According to the results of applying 0%, 1%, and 2% of his body weight on the ankle, except for gait velocity, his gait distance, cadence, step length, stride length, and swing phase were higher when 1% of his body weight was applied compared to 0% or 2% of his body weight. Conclusion: Applying a weight equivalent to 1% of the body weight to the ankle positively affected the visual and spatial element of the gait and heightened the efficiency of exercise during treadmill training, a gait-training tool generally used for stroke patients. However, the result is difficult to generalize because the number of subjects was small with only one subject.

• Bulletin of the Korean Chemical Society
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• 제33권8호
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• pp.2567-2573
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• 2012

We successfully synthesized $Fe_3O_4@SiO_2$ nanoparticles with ultrathin silica layer of $1.0{\pm}0.5$ nm that polyethyleneimine (PEI) with low molecular weight of 2.0-4.0 kDa was covalently conjugated with the resulting $Fe_3O_4@SiO_2$ nanoparticles by silane coupling reaction. The PEI-$Fe_3O_4@SiO_2$ nanoparticles were further used as gene delivery vector for a human fibroblast cell (IMR-90) line. Gene transfection efficiency of the PEI-$Fe_3O_4@SiO_2$ complexes did not increase remarkably after magnetofection; however, the addition of Lipofectamine 2000 significantly increased the transfection efficiency of the PEI-$Fe_3O_4@SiO_2$ complexes. We believe that the present approach could be utilized for magnetofection as alternative to $Fe_3O_4$ nanoparticles conjugated with the PEI of high molecular weight thanks to its relatively low cytotoxicity and high transfection efficiency.

• 대한한의학방제학회지
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• 제19권2호
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• pp.47-59
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• 2011

Objectives : We investigated the effects of gambigyeongsinhwan2(GGH(2)) on body weight and examined whether blood triglyceride levels and visceral fat are inhibited by it in high fat diet-fed obese male mice. Methods : 8 weeks old, high fat diet-fed obese male mice were divided into 5 groups: C57BL/6N normal, control, GGH(2)-1, GGH(2)-2 and GGH(2)-3. After mice were treated with GGH(2) for 8 weeks, we measured body weight gain, food intake, feeding efficiency ratio, fat weight, plasma leptin and lipid levels. We also did histological analysis for liver and fat on the mice. Results : 1. Compared with controls, GGH(2)-treated mice had lower body weight gain and adipose tissue weight, the magnitudes of which were prominent in GGH(2)-3. 2. Compared with controls, GGH(2)-treated mice had lower feeding efficiency ratio, the magnitude of which was prominent in GGH(2)-3. 3. Compared with controls, GGH(2)-treated mice had lower blood plasma triglyceride level. 4. Blood plasma AST and ALT concentrations were not changed by GGH(2), indicating GGH(2) do not show any toxic effects. 5. Consistent with their effects on body weight gain, the size of adipocytes were significantly decreased by GGH(2), whereas the adipocyte number per unit area was significantly increased, suggesting that GGH(2) decreased the number of large adipocytes. Hepatic lipid accumulation was decreased by GGH(2). Conclusions : These results demonstrate that GGH(2) effectively reduces body weight gain, feeding efficiency ratio, blood plasma triglyceride level and improves abdominal fat.