The objective of this study was to determine the extent to which the compensatory nutrition regimen modulates lactation performance and milk protein gene expression in the first and second lactation cycles. Female rats(28 days of age) were assigned to 1)control ad libitum ; 2) stari-step compensatory nutrition(SSCN) regimen an alternating 3-2-3-4-week schedule beginning with an energy restriction diet(40% restriction) for 3 weeks followed by the control diet(ad libitum) for 2 weeks and then alternating another 3-4 week feeding regimen. The SSCN rats were received an overall 20% energy restriction(average from all stair-step periods) compared with the conventionally fed control group. Rats were bred during the first week of the second realimentation. All pups were weaned on day 21 of lactation. About 1 week after weaning all dams were mated for the second pregnancy. Mammary tissues were obtained from pregnant and lactating rats during the first and second lactation cycles. During these lactation cycles the SSCN group had a 11% increase in average lactation performance over that of control. The SSCN group had significantly increased levels of milk protein gene($\alpha$- and $\beta$-casein) expression in mammary tissues during the first lactation cycle compared with those of the control group. During the second lactation period the levels of milk protein gene expression in lactating mammary tissues of the SSCN group were also higher than those of the control group. These results suggest that the effects of compensatory growth imposed at an early age extend to the second lactation cycle with regard to increased lactation performance and milk protein gene expression.
The prevalence of atopic dermatitis (AD) in school-age children has increased in industrialized countries. As diet is one of the main factors provoking AD, some studies have suggested that food additives in processed foods could function as pseudoallergens, which comprise the non-immunoglobulin E-mediated reaction. Eosinophil cationic protein (ECP) is an eosinophil granule protein released during allergic reactions to food allergens in patients with AD. Thus, serum ECP levels may be a useful indicator of ongoing inflammatory processes in patients with AD. The purpose of this study was to investigate the effect of consuming MSG in processed foods on serum ECP levels among children with AD. This study was performed with 13 patients with AD (age, 7-11 years) who had a normal range of total IgE levels (< 300 IU/ml). All participants ate normal diets during the first week. Then, six patients were allocated to a processed food-restricted group (PRDG) and seven patients were in a general diet group (GDG). During the second week, children in the PRDG and their parents were asked to avoid eating all processed foods. On the third week, children in the PRDG were allowed all foods, as were the children in the GDG throughout the 3-week period. The subjects were asked to complete a dietary record during the trial period. Children with AD who received the dietary restriction showed decreased consumption of MSG and decreased serum ECP levels and an improved SCORing score on the atopic dermatitis index (P < 0.05). No differences in serum ECP levels or MSG consumption were observed in the GDG. Serum total IgE levels were not changed in either group. In conclusion, a reduction in MSG intake by restricting processed food consumption may lead to a decrease in serum ECP levels in children with AD and improve AD symptoms.
Purpose: The purpose of the study was to identify the effects of a 9-week self-help management aquatic exercise program on pain, flexibility, balance, fatigue and self-efficacy in the patients with osteoarthritis living in the suburban area. Methods: Utilizing a quasi-experimental design, 43 osteoarthritis patients consisted of the experimental group (n=20) and the control group (n=23). Due to the busy schedule of the patients working in the farm, the program was provided for 9 weeks instead of 12 week program under the guidance of professional advice. The questionnaires and physical measurements were used to measure the outcome variables before and after the program. Data were analyzed with the SPSS WIN using descriptive statistics, t-test and ANCOVA. Results: The age was significantly different between the groups. After controlling for the age, pain and fatigue in the experimental group decreased significantly more than the control group. Flexibility, balance and self-efficacy in the experimental group improved significantly more than the control group. Conclusion: This 9-week program could be an effective nursing intervention to be used especially for osteoarthritis patients in the suburban area during the leisure seasons of the farmers to improve their arthritic symptoms and self-efficacy.
Journal of the Korean Society of Physical Medicine
/
v.1
no.1
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pp.93-108
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2006
Purpose : To evaluate effects of McKenzie exercise on the functional recovery and forward head posture of chronic neck pain patients. Methods : The subjects were consisted of fifteen patients who had abnormal neck posture, mild neck pain (28 males, 17 females; mean aged 21.9) from 19 to 33 years of age(mean age 21.9). All subjects were received McKenzie exercise for 35 minutes with clinical massage per day three times a week during 4 weeks period. Neck disability index was used to measure functional disability level. Visual analogue scale(VAS) was used to measure subjective pain level. craniovetebral angle(CVA), cranial rotation angle(CRA) was used to measure forward head posture with digital camera. All measurements of each patients were measured at pre-treatment and after 2 week, after 4 week, post-treatment on 2 week. Result : The VAS of McKenzie exercise was significantly reduced between pre-treatment and post-treatment (p<.05) and effects of pain reduce was continued follow 2 weeks. The Neck Disability Index of McKenzie exercise was significantly reduced between pre-treatment and post-treatment (p<.05) and effects of pain reduce was continued follow 2 weeks. The CVA of McKenzie exercise was significantly reduced between pre-treatment and post-treatment (p<.05) and effects of pain reduce was continued follow 2 weeks. The CRA of McKenzie exercise was not significantly reduced between pre-treatment and post-treatment (p<.05). Conclusion : McKenzie exercise improved pain and function of Chronic neck pain patients.
Maximal expiratory flow-volume [MEFV] curves were studied in 22 patients who underwent pneumonectomy with various pulmonary lesions, such as lung cancer, bronchiectasis and tuberculosis etc, at the preoperative stage and 3 week, 4 month and 12 month after pneumonectomy for the analysis of the reduction and progressive improvement of postoperative ventilatory function. And the factors affecting them like as age difference and the site of pneumonectomy were also analyzed. From these curves peak flow rate [PF R], maximal expiratory flows at 25% and 50% of expired forced vital capacity [V25, V50] and forced vital capacity [FVC] were obtained. In addition, partial pressure of oxygen and carbon dioxide in arterial blood were measured. The results were as follows; 1. The mixed type, especially obstructive type of ventilatory impairment was observed at 3 week after operation. For 1 year of postpneumonectomy FVC was increased by 12.3% of predicted compared to 2.6% of predicted V50. 2. The improvement of FVC during 1 year of postpneumonectomy showed decreasing tendency with the increase of age but the changes of V25 and V50 were unremarkable. 3. The differences of immediate postoperative reduction and progressive improvement of ventilatory capacity after right and left pneumonectomy were analyzed. The reduction of V50, V25 and FVC at 3 week of postoperation were greater in patients with right pneumonectomy [20.9%, 18.2% and 26.2% of predicted] than in patients with left pneumonectomy 16.5%, 18.2% and 18.1%]. But there was no significant difference of these values at 12 month after pneumonectomy. 4. The partial pressure of oxygen in arterial blood [$PaO_2$] was decreased by 13.6 mmHg at 3 week after pneumonectomy compared to the preoperative stage but returned to the normal range within 4 month after pneumonectomy. However, TEX>$PaCO_2$ was within the normal range during 1 year of postoperation.
Kim, Dong-Hoon;Lee, Youn-Su;Oh, Keon-Bong;Hwang, Seong-Soo;Im, Gi-Sun;Park, Jin-Ki
Reproductive and Developmental Biology
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v.35
no.3
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pp.313-317
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2011
This study was conducted to examine the effect of oocyte donor age and micromanipulation medium on the development of mouse cloned embryos receiving cumulus cells. Mouse oocytes were obtained from 6 to 11 week-old mice BDF1 female mice(experiment 1) and cumulus cells were used as donor cells. Micromanipulation procedures for nuclear transfer(NT) were performed in FHM, M2 or Hepes-buffered TCM199(TCM199) medium(experiment 2). After nuclear transfer, the reconstructed oocytes were activated by 10 mM $SrCl_2$ in Ca-free CZB medium in the presence of 5 II ${\mu}$g/ml cytochalasin B for 5 h and cultured in KSOM medium for 4 days. In experiment 1, the survival rate of oocytes after injection of cumulus cells were significantly(p<0.05) lower in oocytes from 6~7 week-old mice(53.3%) than in oocytes from 8~9(80.9%) and 10~11 week-old mice(77.1%). In experiment 2, the survival rate of oocytes after cell injection were significantly(p<0.05) higher in FHM and M2 medium(71.7% and 76.9%) than in TCM199 medium(51.2%). The activation rates of cloned embryos were not different among the micromanipulation media. However, the embryos developed to blastocyst stage were significantly(p<0.05) higher in FHM medium(13.9%) than in M2 and TCM199 medium(0.0% and 0.0%). In conclusion, the present study suggest that oocytes from above 8 week-old mice are superior to oocytes from 6~7 week-old mice as a source of recipient cytoplasm and FHM is superior to M2 and TCM199 as a micromanipulation medium for mouse somatic cell cloning.
The purpose of this study was to identify the influencing factors of subjective health status among the subjects of the 7th year 3 (2018) National Health and Nutrition Examination Survey, and to help provide programs for improving subjective health status in the future. Data from the 7th Korea National Health and Nutrition Examination Survey(2018) were used. Variables were age, gender, age, subjective health status, subjective body shape recognition, weight change over the past year, usual stress level, walking days per week, and strength training days per week. The higher the number of walking days per week, the lower the usual stress perception level. As the number of strength training days per week increased, the level of stress perception was lower (p<.001). The subjects' subjective health status was found to have a negative effect on their usual stress perception (β=-.759), subjective body shape (β=.111), age (β=.421), and number of days walking per week. (β=.968). Based on this study, it is intended to provide basic data for preparing programs to help improve stress perception and subjective health status in the future.
This study investigated the growth characteristics of four strains of newly developed synthetic Korean native commercial chickens (KNCs). We investigated a suitable growth curve model in KNCs and estimated the number of days to reach a 2 kg market weight. Body weight was measured at 2-week intervals from birth to 12 weeks of age. The growth curves were estimated using von Berteralanffy, Gompertz, and logistic functions. The results showed that males were significantly heavier than females at all ages, but there were no significant differences in body weight between strains, except at birth and 2 and 6 weeks of age. The coefficients of determination and adjusted determination of growth function had high goodness-of-fit (97.4~99.7). Of the growth curve parameters, the mature weight and growth ratio were higher in males than in females, but the maturity rate was similar in males and females. The inflection point occurred at approximately 7 weeks of age for females and 8 to 9 weeks of age for males. The weights estimated from the growth curve functions almost agreed with the actual weights, except for male weights estimated using the von Bertalanffy function. The coefficients of determination of the regression equations for weight to age were 0.9583 to 0.9746. The 8- and 10-week-old body weights estimated using the regression equation, and the 12-week-old weight estimated using the logistic function were most similar to the actual weight. Using these models, the estimated age of KNCs to reach 2 kg was 62.0~64.6 days for males and 74.9~78.6 days for females.
In most of the previous studies, invasive and discrete techniques have been used to monitor the healing process of the gingival graft. However, Laser Doppler Flowmetry(LDF, floLAB(R), Moor Instruments Ltd., England) is a non-invasive technique for measurement of blood flow in the tissue and also allows continuous monitoring. Thus, we tested the usefulness of LDF in monitoring the healing process of free gingival graft at gingival recession. Eleven gingival graft site of 7 patients, including 5 males and 2 females, aged between 21 and 41 years (mean age 28.5) were monitored for the blood flow. The blood flow in gingival graft at coronal site, central site, apical site, mesial site and distal site was measured using LDF. Blood flow was measured at 1- week, 2- week, 3- week and 4- week after gingival graft surgery from 10 a.m. to 2 p.m. Time-course of the healing process was evaluated by statistical analysis using repeated ANOVA and Duncan test. The results were as follows : (1) Blood flow stayed increased for 2 weeks, and then, it was a tendency to decrease. (2) The blood flow at distal site had always higher than mesial site during the measuring periods. (3) The blood flow was high orderly after 1 week ; most coronal site, most apical site, central site. But that was high orderly after 2 week, 3 week, 4 week ; most coronal site, central site, most apical site. In conclusion, LDF was a useful and clinically adaptable method to monitor wound healing process. Our study suggested that it was important to protect surgical site to promote initial wound healing.
Jun Seon Hong;Myunghwan Yu;Elijah Ogola Oketch;Shan Randima Nawarathne;Doo Ho Lee;Minjun Kim;Jung Min Heo
Korean Journal of Agricultural Science
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v.49
no.4
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pp.1033-1040
/
2022
The current experiment was conducted to evaluate the effect of diallel crossbreeding on the body weight and laying performance of Korean native chicken from hatch to week 40. A total of 1,000 one-day-old chicks were allotted to 10 cages per crossbreeding treatment with 10 birds per cage on a random basis and then raised until 16 weeks and subsequently moved to layer battery cages and raised until 40 weeks. Ten crossbred treatments (YC, YD, YF, YK, CD, CF, CK, DF, DK, FK) that were obtained from the diallel crossbred of five pure lines were used in the current experiment. The body weight and mortality were measured biweekly from hatching to week 20 and every four weeks from week 20 to week 40. The number of eggs was measured daily. YC and YD crossbreeds showed a higher body weight (p < 0.05) and FK crossbreed showed a lower body weight (p < 0.05) during the whole xperimental period. The week 20 weight range was 1,501 to 1,729 g and the week 40 weight range was from 1,829 to 2,179 g. Earlier onset of egg-laying was noted in the YC and YD groups whereas late onset was observed for the DF and DK groups. YK reached its peak earliest at week 25 with 89.15% while the DK crossbreed attained its peak at week 36 with 89.69%. The YC and YD crossbreeds showed the improved body and egg-laying performance. Conclusively, there are variations in the body weight and laying performance of Korean native chickens with diallel crossing.
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