• Asian Pacific Journal of Cancer Prevention
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• 제13권10호
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• pp.5105-5111
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• 2012

Background: Published data on the association between single nucleotide polymorphisms (SNPs) in the ESR1 gene and breast cancer susceptibility are inconclusive or controversial. The aim of this Human Genome Epidemiology (HuGE) review and meta-analysis was to derive a more precise estimation of this relationship. Methods: A literature search of Pubmed, Embase, Web of science and CBM databases was conducted from inception through September 1th, 2012. Crude odds ratios (ORs) with 95% confidence intervals (CIs) were used to assess the strength of association. Results: A total of five studies including 1,678 breast cancer cases and 1,678 general population controls in Asian populations were involved in this meta-analysis. When all the eligible studies were pooled into the meta-analysis, the higher transcriptional activity variant allele T of ESR1 PvuII (C>T) (rs2234693) in pre-menopausal breast cancer women showed a significant relation to increased risk (OR = 1.13, 95%CI: 1.01-1.28, P = 0.040) in contrast to their post-menopausal counterparts which showed non-significant increased risk (OR = 1.01, 95%CI: 0.87-1.18, P = 0.858). Nevertheless, no significant association between ESR1 XbaI (A>G) (rs9340799) polymorphism and the risk of breast cancer was observed in pre-menopausal and post-menopausal individuals. Conclusion: Based on a homogeneous Asian population, results from the current meta-analysis indicates that the ESR1 PvuII (C>T) polymorphism places pre-menopausal breast cancer women at risk for breast cancer, while ESR1 XbaI (A>G) polymorphism is not likely to predict the risk of breast cancer.

• 한국의류학회지
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• 제29권6호
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• pp.847-858
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• 2005

The purpose of this study was to examine consumer purchasing behavior of the online shoppers particularly using online clothing shopping mall and to analyze the key factors of both satisfaction and dissatisfaction of their purchase and to compare the both group by lifestyle segmentation in order to provide the e-CRM strategies. Focus group interviews and survey were conducted in December, 2003 with 30 online shoppers who have an experience of online clothing purchasing. The data analysis included the content analysis, descriptive statistics, K-means and factor analysis. Key findings of the study were as follows: First, online shoppers spent average 3.5 hours on internet and usually purchased clothing while surfing the web. Second, consumers were satisfied with reasonable price and customized service but dissatisfied with delayed delivery, limited product availability in both size and color and return policy. Third, according to the lifestyle segmentation, online shoppers could be characterized as 'Luxurious', 'Trendy' and 'Prudent' 'Luxury-oriented consumers', who value fashion, diet and social activity, tended to purchase basic yet high quality products. However, 'Trend-oriented consumers', to whom fashion trend was most important, purchased various latest fashion products with reasonable price and showed generally positive response to emails sent by e-retailers. And lastly 'Prudence-oriented consumers', whose buying decision was based solely on practicality, appeared to be reluctant to purchase clothing online while seeking more credible information and competitive price. In conclusion, this study has its significance in that it helps promote relationships between customers and e-retailers by providing differentiated e-CRM strategies through each customer groups 'lifestyle segmentation and consumer purchasing behavior analysis.

• 대한약침학회지
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• 제20권3호
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• pp.173-178
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• 2017

Objectives: Medicinal plants are vital sources of bioactive compounds that are useful for the treatment of patients with snake bites or are indirectly applicable for boosting the effects of conventional serum therapy. These plants are being used traditionally by local healers and tribes for the treatment of patients with snake bites and therefore can be used as an alternative against snake envenomation. Scientifically, using the secondary metabolites of plants to neutralize venom enzymes has an extra benefit of being based on traditional knowledge; also, the use of such metabolites for the treatment of patients with snake bites is cheaper and the treatment can be started sooner. Methods: All the available information on various secondary metabolites exhibiting venom neutralizing ability were collected via electronic search (using Google books, Pubmed, SciFinder, Scirus, Google Scholar, and Web of Science) and articles of peer-reviewed journals. Results:Recent interest in different plant has focused on isolating and identifying of different phytoconstituents that exhibit Phospholipase A2 activity and other venom enzyme neutralizing ability. In this support convincing evidence in experimental animal models are available. Conclusion: Secondary metabolites are naturally present, have no side effect, are stable for a long time, can be easily stored, and can neutralize a wide range of snake enzymes, such as phospholipase A2, hyaluronidase, protease, L-amino acid oxidase, 5'nucleotidase, etc. The current review presents a compilation of important plant secondary metabolites that are effective against snake venom due to enzyme neutralization.

• 컴퓨터교육학회논문지
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• 제10권6호
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• pp.11-18
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• 2007

본 논문에서 구현된 논리회로 가상실험실은 원리이해를 위한 개념학습실과 가상 디지털 키트에 의한 가상실험실의 두 단계로 설계하였다. 개념학습실에서 학습자는 디지털 논리회로에 대한 중요한 원리나 의미를 쉽게 이해할 수 있도록 하였다. 가상실험실에서는 가상 브레드보드에서 회로를 결선하여 입력전압을 인가하여 출력신호를 측정한 다음 가상실험데이터와 비교하여 서버로 전송한다. 가상실험실에서 수행된 모든 실험활동은 데이터베이스에 저장되어 개인정보와 함께 예비보고서의 형태로 제공되어 교수자는 학습자가 얼마나 회로동작에 대해 잘 이해하였는가를 점검할 수 있도록 하였다. 마지막으로 제안된 가상실험시스템의 유효성을 입증하기 위해 한 학기 동안 실험 중에 발생한 실제 장비의 파손율과 학생들의 성취도를 5개의 설문을 통해 조사하여 분석하였다.

• 한국환경보건학회지
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• 제45권6호
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• pp.613-621
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• 2019

Objectives: This study was performed to examine the relationship between health behaviors, living environment, and asthma in adolescents in Korea. Methods: Information on adolescents' characteristics, including demographic factors, health behaviors, and doctor's diagnosis of asthma was obtained from the Korean Youth Risk Behavior Web-based Survey (2015). In total, 68,043 middle and high school students participated. Environmental characteristics, including city park area and outdoor PM₁₀ concentrations in 2015 were obtained from the Korean Statistical Information Service. The adolescents' and environmental characteristics were merged by local information. Multiple logistic regression models were used to investigate the risk factors affecting asthma in adolescents. Results: The prevalence of asthma in adolescents in 2015 was 8.8%. In the multiple logistic regression analysis, adolescents who were male, attended middle school, suffered obesity, experienced tobacco smoking, had physical activity levels of 2 to 4 days, had higher stress levels, and lived in areas with outdoor PM₁₀ concentrations more than 47 ㎍/㎥ were more likely to have asthma, while adolescents who had middle levels of family economic status were less likely to do so. Conclusions: The fact that PM₁₀ concentration can affect asthma is an important point in this study. Risk factors identified in this study could be used as basic data for the prevention and management of asthma in Korea.

• 정보보호학회논문지
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• 제24권3호
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• pp.499-505
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• 2014

스마트폰, 태블릿과 같은 스마트 기기의 사용이 늘어남에 따라 스마트 기기를 대상으로 하는 모바일 오피스, 금융 서비스, 모바일 전자정부 등 생산성이나 사용자 편의를 위한 서비스들이 대거 등장하였다. 이에 따라 중요한 정보들이 스마트 기기를 통해 다루어져 스마트 기기를 대상으로 하는 악성행위가 꾸준히 증가하고 있다. 특히 스마트 기기를 대상으로 하는 유해사이트, 악성코드 배포 사이트, 피싱(phishing) 사이트 등으로 인한 피해사례가 꾸준히 발생하고 있어 사회적인 이슈로 부각되고 있다. 스마트 기기의 경우 2013년 국내에서 사용하는 플랫폼의 90%가 안드로이드를 사용하고 있어 단말 수준의 차단방법이 필요하였다. 본 논문에서는 안드로이드 플랫폼에서 웹브라우저를 사용하여 악성사이트를 방문할 때 효과적으로 차단할 수 있는 방법을 기술하고 실제 애플리케이션으로 구현하여 악성사이트 차단성능을 분석하였다.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 2011년도 추계학술대회
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• pp.858-861
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• 2011

본 논문에서는 무선 센서 네트워크를 이용한 RFID 시스템을 제안한다. 제안한 시스템은 활동 모니터링을 위해 장갑 형태로 구성되며, RFID 리더기는 센서 네트워크 기반으로 데이터를 전송하며, RFID 태그는 13.56MHz에서 동작하고, 사각형의 작은 사이즈로 구성된다. 센서 노드는 가구나 약병, 주방용품 등의 다양한 일상생활 물체에 부착된 RFID 태그를 읽는다. 센서 노드는 무선 패킷을 싱크노드로 전송하고, 싱크노드는 수신된 패킷을 서버로 전달한다. RFID 시스템에서 전달된 데이터는 데이터베이스에 저장되고, 사용자의 일상생활 활동정보를 표시한다. 웹기반의 모니터링 시스템을 제공하고, RFID 태그의 회수를 하루단위로 막대 차트로 확인할 수 있다. 실험을 통해서 제안한 방식이 노약자의 행동이나 생활 습관 등을 감지하고 인식할 수 있음을 확인하였다.

• 대한지역사회영양학회지
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• 제13권3호
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• pp.386-395
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• 2008

Since obesity has been a crucial issue regarding children's health in Korea, numerous studies have been conducted. However, it is difficult to locate studies that can help researchers and/or medical professionals who want to study behavioral differences between obese and normal weight (non-obese) children. The collected literature about obese childrens behaviors were accumulated by performing 'key word' searches from several web engines: 'obesity' 'children obesity' 'behavior' 'habit' 'eating behavior or habit' 'exercise' 'physical activity' and 'daily behavior'. The information was extracted and the behaviors were reviewed utilizing 30 papers that revealed any differences from normal weight children with at least p .05 level of significance. According to those studies, the obese children tended to skip meals more often as a method of losing weight. They also have an increased appetite, eat larger portions and rarely leave food on their plates. The obese children prefer to eat high fat, high calorie foods and eat faster than their normal weight counterparts. Also, the children usually eat alone and eat at irregular meal times. Beside the behaviors related to the standard three meals a day, obese children have high preferences for snacking. The children reported that with pocket money they usually eat certain types of snacks without parent approval. The children stated that they exercise more on a regular basis. However, when asked about their participation they were not likely to engage actively. Meanwhile, they tend to spend free time doing sedentary activities such as watching TV or playing on the computer. Since these studies used self -reported questionnaires with a small sample, size there may be difficulty in forming a basis about obese children's behaviors. Nevertheless, these findings are in accordance with other studies conducted in local as well as western countries. In conclusion, obese children have different daily behaviors or routines from normal weight children. It is recommended that altering these behavioral patterns to match those of normal weight children should be encouraged.

• 한국운동역학회지
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• 제30권2호
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• pp.185-195
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• 2020

Objective: The purpose of this study was to identify recent domestic and international research trends regarding shoes carried out in biomechanics field and to suggest the direction of shoe research later. Method: To achieve this goal of research, the Web of Science, Scopus, PubMed, Korea Education and Research Information Service and Korean Citation Index were searched to identify trends in 64 domestic and international research. Also, classified into the interaction of the human body, usability evaluation of functional shoes, smart shoe development research, and suggested the following are the suggestions for future research directions. Conclusion: A study for the coordination of muscle activity, control of motion and prevention of injury should be sought by developing shoes of eco-friendly materials, and scientific evidence such as physical aspects, materials, floor shapes and friction should be supported. Second, a study on elite athletes in various sports is needed based on functional shoes using new materials to improve their performance along with cooperation in muscle activities and prevention of injury. Third, various information and energy production are possible in real time through human behavioral information, and the application of Human Machine Interface (HMI) technology through shoe-sensor-human interaction should be explored.

• Nuclear Engineering and Technology
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• 제42권4호
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• pp.339-364
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• 2010

Following a joint OECD/NEA-IAEA-sponsored meeting to define the current role and future perspectives of the application of Computational Fluid Dynamics (CFD) to nuclear reactor safety problems, three Writing Groups were created, under the auspices of the NEA working group WGAMA, to produce state-of-the-art reports on different aspects of the subject. The work of the second group, WG2, was to document the existing assessment databases for CFD simulation in the context of Nuclear Reactor Safety (NRS) analysis, to gain a measure of the degree of quality and trust in CFD as a numerical analysis tool, and to take initiatives to extend the existing databases. The group worked over the period of 2003-2007 and produced a final state-of-the-art report. The present paper summarises the material gathered during the study, illustrating the points with a few highlights. A total of 22 safety issues were identified for which the application of CFD was considered to potentially bring real benefits in terms of better understanding and increased safety. A list of the existing databases was drawn up and synthesised, both from the nuclear area and from other parallel, non-nuclear, industrial activities. The gaps in the technology base were also identified and discussed. In order to initiate new ways of bringing experimentalists and numerical analysts together, an international workshop -- CFD4NRS (the first in a series) -- was organised, a new blind benchmark activity was set up based on turbulent mixing in T-junctions, and a Wiki-type web portal was created to offer online access to the material put together by the group giving the reader the opportunity to update and extend the contents to keep the information source topical and dynamic.