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Development of Prototype for Screening Anti-Inflammation Effects concerning p38 MAPK Signal Pathway (p38 MAPK을 이용한 항염증 효능 규명 프로토타입 개발)

  • Kim, Chul;Yae, Sang-Jun;Nam, Ky-Youb;Kim, Sang-Kyun;Jang, Hyun-Chul;Kim, Jin-Hyun;Kim, Young-Eun;Song, Mi-Young
    • Korean Journal of Oriental Medicine
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    • v.17 no.3
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    • pp.77-85
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    • 2011
  • Objectives : The purpose of this study was to develop a simulator which can analyze the anti-inflammatory effects of medical herbs based on e-cell concerning p38 MAPK signal pathway. Methods : We collected data concerning medical herbs with anti-inflammatory effects and the active compounds to provide as a fundamental databse and to validate the newly developed algorithm. At this time, we used the target database as pubmed and gathered the data by data mining tool, pathway studio. Also we have developed the web-based search system for confirming database related to anti-inflammation. We researched the mechanism of actions of proteins in p38 MAPK signal pathway when active compound has been inserted into the network. We reduced total network into TAK-MKK3-p38 and made the two types of mathematical model about active compounds' interaction. Results & Conclusion : We constructed the database which have 69 cases of medical herbs, 71 cases of active compounds, about 8,000 cases of URL(Uniform Resource Locator) related to papers and reports. We designed the ordinary differential equations for response of TAK, MKK3, p38 in e-cell's cytosol and nucleus. We used this formular as measure whether an active compound of medicinal plants which is inputted by an user would have an anti-inflammation effects. We developed the visualization program which could show the change of concentration over time.

Age-dependent root canal instrumentation techniques: a comprehensive narrative review

  • Solomonov, Michael;Kim, Hyeon-Cheol;Hadad, Avi;Levy, Dan Henry;Itzhak, Joe Ben;Levinson, Oleg;Azizi, Hadas
    • Restorative Dentistry and Endodontics
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    • v.45 no.2
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    • pp.21.1-21.12
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    • 2020
  • The aim of this article was to review age-dependent clinical recommendations for appropriate root canal instrumentation techniques. A comprehensive narrative review of canal morphology, the structural characteristics of dentin, and endodontic outcomes at different ages was undertaken instead of a systematic review. An electronic literature search was carried out, including the Medline (Ovid), PubMed, and Web of Science databases. The searches used controlled vocabulary and free-text terms, as follows: 'age-related root canal treatment,' 'age-related instrumentation,' 'age-related chemo-mechanical preparation,' 'age-related endodontic clinical recommendations,' 'root canal instrumentation at different ages,' 'geriatric root canal treatment,' and 'pediatric root canal treatment.' Due to the lack of literature with practical age-based clinical recommendations for an appropriate root canal instrumentation technique, a narrative review was conducted to suggest a clinical algorithm for choosing the most appropriate instrumentation technique during root canal treatment. Based on the evidence found through the narrative review, an age-related clinical algorithm for choosing appropriate instrumentation during root canal treatment was proposed. Age affects the morphology of the root canal system and the structural characteristics of dentin. The clinician's awareness of root canal morphology and dentin characteristics can influence the choice of instruments for root canal treatment.

An XML Tag Indexing Method Using on Lexical Similarity (XML 태그를 분류에 따른 가중치 결정)

  • Jeong, Hye-Jin;Kim, Yong-Sung
    • The KIPS Transactions:PartB
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    • v.16B no.1
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    • pp.71-78
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    • 2009
  • For more effective index extraction and index weight determination, studies of extracting indices are carried out by using document content as well as structure. However, most of studies are concentrating in calculating the importance of context rather than that of XML tag. These conventional studies determine its importance from the aspect of common sense rather than verifying that through an objective experiment. This paper, for the automatic indexing by using the tag information of XML document that has taken its place as the standard for web document management, classifies major tags of constructing a paper according to its importance and calculates the term weight extracted from the tag of low weight. By using the weight obtained, this paper proposes a method of calculating the final weight while updating the term weight extracted from the tag of high weight. In order to determine more objective weight, this paper tests the tag that user considers as important and reflects it in calculating the weight by classifying its importance according to the result. Then by comparing with the search performance while using the index weight calculated by applying a method of determining existing tag importance, it verifies effectiveness of the index weight calculated by applying the method proposed in this paper.

A Study on Music Contents Recommendation Service using Emotional Words (감성어휘를 이용한 음악콘텐츠 추천 서비스의 연구)

  • Jang, Eun-Ji
    • Proceedings of the Korea Contents Association Conference
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    • 2008.05a
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    • pp.43-48
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    • 2008
  • And this study intends to discuss especially the one using emotional filter among various information processing methods. The existing music recommendation service on the web has a weak point that it makes the user feel bored by recommending songs only with similar feeling of the same genre, because music is classified by tune, melody, atmosphere and genre before recommendation. The service using emotion filter, suggested in this study, recommends the song and lyrics appropriate to the current emotional state of the user by abstracting emotional words that could reflect the sensitivity of human and then search the words within lyrics to match in order to overcome the weak point of the existing service. This study starts where the current emotional status for the user is being input. As for the range to choose, there are the seven representatives of emotion which are, love, separation, joy, sorrow-gloom, happiness-lonesome, and anger. As the service receives input of user's emotion, it matches the emotional words appropriate for the emotion input with the lyrics, and ranks the lyrics in the order of priority, so that it recommends the song and it lyrics to the user.

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Features for Author Disambiguation (저자 식별을 위한 자질 비교)

  • Kang, In-Su;Lee, Seung-Woo;Jung, Han-Min;Kim, Pyung;Koo, Hee-Kwan;Lee, Mi-Kyung;Sung, Won-Kyung;Park, Dong-In
    • The Journal of the Korea Contents Association
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    • v.8 no.2
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    • pp.41-47
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    • 2008
  • There exists a many-to-many mapping relationship between persons and their names. A person may have multiple names, and different persons may share the same name. These synonymous and homonymous names may severely deteriorate the recall and precision of the person search, respectively. This study addresses the characteristics of features for resolving homonymous author names appearing in citation data. As disambiguation features, previous works have employed citation-internal features such as co-authorship, titles of articles, titles of publications as well as citation-external features such as emails, affiliations, Web evidences. To the best of our knowledge, however, there has been no literature to deal with the influences of features on author disambiguation. This study analyzes the effect of individual features on author resolution using a large-scale test set for Korean.

Development of Optimal Routes Guidance System based on GIS (GIS기반 최적 경로안내 시스템 개발)

  • Yoo, Hwan-Hee;Woo, Hae-In;Lee, Tae-Soo
    • Journal of Korean Society for Geospatial Information Science
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    • v.10 no.1 s.19
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    • pp.59-66
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    • 2002
  • The rapid change of industrial structure causes to increase distribution cost and requires necessity of physical distribution system urgently. Traffic situation is getting extremely worse and traffic jam has led to increasing expense of physical distribution delivery which dominates 20% of distribution cost. In this situation, the shortest and most suitable path search system is required by modern people who must waste a lot of time for moving with a car or on the street as well as many companies. for these reasons, we developed the shortest-path-searching system applying the dijkstra algorithm which is one of the effective shortest path algorithm to GIS, and it was constructed by considering realistic urban traffic and the pattern of street in a physical situation. Also, this system was developed to be updated weight data automatically, considering the dynamic change of traffic situation such as a traffic information service which will be served in real time. Finally, we designed this system to serve on web by using MapObjects IMS.

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Design of DRM System in P2P Network Environment (P2P네트워크 환경을 위한 DRM 시스템 설계)

  • Lee Jeong-Gi;Kim Kuk-Se;Lee Gwang;Ahn Seong-Soo;Lee Joon
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2006.05a
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    • pp.829-832
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    • 2006
  • The word P2P implies significant changes in current business dynamics. The P2P service enables individuals to be connected to the Internet for the direct provision of information and even downloads from one another without the conventional method of passing through search engines. This can be utilized to extend the path of retrieving information from limited web sites to personal and enterprise databases. That is, it is now possible for individuals to manage their own information on a national or global scope, share various information with other members, form communities of users interested in sharing homogeneous information, and utilize remote conference and remote education using groupware.

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An Insight Study on Keyword of IoT Utilizing Big Data Analysis (빅데이터 분석을 활용한 사물인터넷 키워드에 관한 조망)

  • Nam, Soo-Tai;Kim, Do-Goan;Jin, Chan-Yong
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2017.10a
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    • pp.146-147
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    • 2017
  • Big data analysis is a technique for effectively analyzing unstructured data such as the Internet, social network services, web documents generated in the mobile environment, e-mail, and social data, as well as well formed structured data in a database. The most big data analysis techniques are data mining, machine learning, natural language processing, and pattern recognition, which were used in existing statistics and computer science. Global research institutes have identified analysis of big data as the most noteworthy new technology since 2011. Therefore, companies in most industries are making efforts to create new value through the application of big data. In this study, we analyzed using the Social Matrics which a big data analysis tool of Daum communications. We analyzed public perceptions of "Internet of things" keyword, one month as of october 8, 2017. The results of the big data analysis are as follows. First, the 1st related search keyword of the keyword of the "Internet of things" has been found to be technology (995). This study suggests theoretical implications based on the results.

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An Efficient Algorithm for Mining Interactive Communication Sequence Patterns (대화형 통신 순서열 패턴의 마이닝을 위한 효율적인 알고리즘)

  • Haam, Deok-Min;Song, Ji-Hwan;Kim, Myoung-Ho
    • Journal of KIISE:Databases
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    • v.36 no.3
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    • pp.169-179
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    • 2009
  • Communication log data consist of communication events such as sending and receiving e-mail or instance message and visiting web sites, etc. Many countries including USA and EU enforce the retention of these data on the communication service providers for the purpose of investigating or detecting criminals through the Internet. Because size of the retained data is very large, the efficient method for extracting valuable information from the data is needed for Law Enforcement Authorities to use the retained data. This paper defines the Interactive Communication Sequence Patterns(ICSPs) that is the important information when each communication event in communication log data consists of sender, receiver, and timestamp of this event. We also define a Mining(FDICSP) problem to discover such patterns and propose a method called Fast Discovering Interactive Communication Sequence Pattern(FDICSP) to solve this problem. FDICSP focuses on the characteristics of ICS to reduce the search space when it finds longer sequences by using shorter sequences. Thus, FDICSP can find Interactive Communication Sequence Patterns efficiently.

Crowdsourcing Software Development: Task Assignment Using PDDL Artificial Intelligence Planning

  • Tunio, Muhammad Zahid;Luo, Haiyong;Wang, Cong;Zhao, Fang;Shao, Wenhua;Pathan, Zulfiqar Hussain
    • Journal of Information Processing Systems
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    • v.14 no.1
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    • pp.129-139
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    • 2018
  • The crowdsourcing software development (CSD) is growing rapidly in the open call format in a competitive environment. In CSD, tasks are posted on a web-based CSD platform for CSD workers to compete for the task and win rewards. Task searching and assigning are very important aspects of the CSD environment because tasks posted on different platforms are in hundreds. To search and evaluate a thousand submissions on the platform are very difficult and time-consuming process for both the developer and platform. However, there are many other problems that are affecting CSD quality and reliability of CSD workers to assign the task which include the required knowledge, large participation, time complexity and incentive motivations. In order to attract the right person for the right task, the execution of action plans will help the CSD platform as well the CSD worker for the best matching with their tasks. This study formalized the task assignment method by utilizing different situations in a CSD competition-based environment in artificial intelligence (AI) planning. The results from this study suggested that assigning the task has many challenges whenever there are undefined conditions, especially in a competitive environment. Our main focus is to evaluate the AI automated planning to provide the best possible solution to matching the CSD worker with their personality type.