• 약학회지
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• 제30권6호
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• pp.311-316
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• 1986

A new UV labeling reagent was developed and used in HPLC for the determination of prostaglandin $E_2$ which have weak UV light-absorbing property. This reagent, 2-bromoacetyltriphenylene, was synthesized by the bromination of 2-acetyltriphenylene which was obtained from triphenylene by Friedel-Crafts reaction. The wave length maximum (${\lambda}_{max}^{CH_3CN}$ of this reagent was 268nm. Prostaglandin E$_2$ was extracted from prostaglandin E$_2$-$\beta$-cyclodextrin using a Sep-pak $C_{18}$ cartridge. The prostaglandin E$_2$ was labeled with 2-bromoacetyl-triphenylene in aectonitrite using 18-crown-6-ether as catalyst. Derivatized prostaglandins were separated on a reversed-phase column (Radial-pak) $\mu$-Bondapak $C_{18}$ using acetonitrile: water=60:40 as mobile phase. The effluent was monitored by UV detector at 254nm filter kit. Linearity of calibration curve was obtained between 30ng and 140ng, and the lower limit of detection was 5ng.

• 한국지하수토양환경학회:학술대회논문집
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• 한국지하수토양환경학회 2004년도 임시총회 및 추계학술발표회
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• pp.33-36
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• 2004

Two biokinetic models (\circled1 Mrichaelis-Menten kinetics with competitive inhibition \circled2 with both competitive inhibition and Haldane inhibition) for reductive dechlorination were developed and compared with results from batch kinetic tests conducted over a wide range of PCE and TCE concentrations with two different dechlorinating cultures. At PCE concentrations lower than 300 $\mu$M, both model simulated the experimental results well. However, The kinetic model that incorporated both competitive and Haldane inhibitions much better simulated experimental data for PCE concentrations greater than 300-400 $\mu$M, and TCE concentrations at half its solubility limit (4000 $\mu$M). The PM culture showed Haldane inhibition constants of 900, 6000, 7000 $\mu$M for TCE, c-DCE and VC, indicating very weak Haldane inhibition for c-DCE and VC, while the EV culture had lower Haldane inhibition constants for TCE, c-DCE, and VC of 900, 750, and 750 $\mu$M, respectively. The BM culture had better transformation abilities than the individual cultures over a wide range of PCE and TCE concentrations. Modeling results indicated that a combination of competitive and Haldane inhibition kinetics is required to simulate dechlorination over a broad range of concentrations up to the solubility limits of PCE and TCE.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제8권6호
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• pp.2139-2151
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• 2014

Embedded system testing, especially long-term reliability testing, of flash memory solutions such as embedded multi-media card, secure digital card and solid-state drive involves strategic decision making related to test sample size to achieve high test coverage. The test sample size is the number of flash memory devices used in a test. Earlier, there were physical limitations on the testing period and the number of test devices that could be used. Hence, decisions regarding the sample size depended on the experience of human testers owing to the absence of well-defined standards. Moreover, a lack of understanding of the importance of the sample size resulted in field defects due to unexpected user scenarios. In worst cases, users finally detected these defects after several years. In this paper, we propose that a large number of potential field defects can be detected if an adequately large test sample size is used to target weak features during long-term reliability testing of flash memory solutions. In general, a larger test sample size yields better results. However, owing to the limited availability of physical resources, there is a limit on the test sample size that can be used. In this paper, we address this problem by proposing a self-adaptive reliability testing scheme to decide the sample size for effective long-term reliability testing.

• Bulletin of the Korean Chemical Society
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• 제33권1호
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• pp.204-208
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• 2012

A novel chemiluminescence (CL) flow injection method for the determination of balofloxacin is described. The method is based on the weak CL signal arising from the reaction of $KBrO_3$ with $Na_2S_2O_4$ in acidic medium being significantly enhanced by balofloxacin in the presence of europium (III) ion and sodium dodecyl benzene sulfonate (SDBS). The experimental conditions that affected CL intensity were carefully optimized and the CL reaction mechanism was briefly discussed. Under the optimum conditions, the relative CL intensity was proportional to the concentration of balofloxacin in the range of $7.0{\times}10^{-11}$ to $3.0{\times}10^{-7}g\;mL^{-1}$. The detection limit was $2.7{\times}10^{-11}g\;mL^{-1}$ and the relative standard deviation was 2.1% for $7.0{\times}10^{-10}g\;mL^{-1}$ balofloxacin (n = 13). The proposed method was successfully applied to the determination of balofloxacin in pharmaceutical formulations and biological fluids.

• Bulletin of the Korean Chemical Society
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• 제35권2호
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• pp.489-493
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• 2014

A phenylbenzimidazole derivatized sensor (L) that behaves as a ratiometric fluorescent receptor for $Zn^{2+}$ in water has been described. In HEPES buffer at pH 7.4, sensor L displays a weak fluorescence emission band at 367 nm. Upon addition of $Zn^{2+}$, the emission intensity at 367 nm is decreased, concomitantly, a new emission band centered at 426 nm is developed, thus facilitates a ratiometric $Zn^{2+}$ sensing behavior. Sensor L binds $Zn^{2+}$ through a 1:1 binding stoichiometry with high selectivity over other metal cations. Sensor L displays a linear response to $Zn^{2+}$ concentration from 0 to $6.0{\times}10^{-5}M$, sensor L also exhibits high sensitivity to $Zn^{2+}$ with a detection limit of $3.31{\times}10^{-7}M$.

• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 2005년도 봄학술 발표회 논문집(I)
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• pp.111-114
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• 2005

While the existing reinforced concrete flat plate(RC flat plate) has a lot of advantages including reduced building height, it has some weak points such as many steel bars and the brittle rupture by punching shear. Compared with the RC flat plate, the post-tensioned flat plate (PT flat plate) has not only the same merits, but it also makes longer span possible and induces slab-column connections to be failed with the ductile behavior rather than with the brittle behavior by means of post-tensioning. However, it is difficult to define the joint behavior of PT flat plate under vertical and lateral loads since there are limit experimental results. For this reason, the experimental study is undertaken to investigate the comparison of behavior of PT flat plate and RC flat plate, and how flat plate(Gravity Load Resisting System) is displaced as lateral loads, like the wind and the earthquake, are occur. The result of this experiment shows that PT flat plate is generally superior to RC flat plate in terms of controlling crack, postponing stiffness deterioration, energy dissipation, etc.

• 대한전자공학회논문지TC
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• 제45권7호
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• pp.1-8
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• 2008

Low Density Parity Check codes(LDPC)는 최근 우수한 성능으로 통신 분야에서 채널 코딩의 중요한 블록으로 주목받고 있다. 그리하여 Wibro를 포함한 여러 표준에서 LDPC 부호를 채널 코딩으로 채택하고 있다. 이러한 LDPC 부호의 Encoder를 구현하는데 있어서의 약점은 기존의 이진 Matrix Vector Multiplier가 throughput의 감소의 원인이 되는 clock cycle이 많다는 것이다. 본 논문은 표준에서 사용되는 H 행렬이 Circulant Permutation Matrix(CPM)로 정의되어 있다는 점을 이용하여 인코더의 구현에 있어서 기존의 Matrix Vector Multiplier 대신에 cyclic shift register와 exclusive-OR을 사용하는 설계구조를 제안한다. 또한, 제안한 구조를 이용하여 WiBro에 포함되는 다양한 부호율에 적용가능한 인코더를 설계하였다. 제안된 WiBro LDPC의 인코더는 기존보다 적은 clock cycle을 가지므로 높은 throughput에 도달한다.

• 천문학회보
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• 제37권2호
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• pp.75.1-75.1
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• 2012

Narrow-Line Seyfert 1 galaxies are arguably the most important AGN subclass in investigating the origin of the black hole mass-galaxy stellar velocity dispersion (MBH-${\sigma}$) relation because of their high accretion rates close to the Eddington limit. Currently, it is still under discussion whether NLS1s are off from the local MBH-${\sigma}$ relation. We select a sample of 325 NLS1 at relatively low redshift (z<0.1) from the SDSS DR7 by constraining FWHM of $H{\beta}$ in the range of 800-2,200 km/s. Among them, we measured stellar velocity dispersion of 40 objects which show strong stellar absorption lines, e.g. Mg b triplet(${\sim}5175{\AA}$), Fe($5270{\AA}$). In contrast, the other 285 objects show too weak stellar absorption lines to measure velocity dispersion. Using the sample of 40 objects with stellar velocity dispersion measurements, we investigate whether NLS1s follow the same MBH-${\sigma}$ relation as normal galaxies and broad line AGNs. We also test the reliability of the width of narrow lines as a surrogate of stellar velocity dispersion by comparing directly measured stellar velocity dispersion with ${\sigma}$ inferred from [O III], [N II], [S II] line widths, respectively. We will discuss the connection between AGN activity in NLS1s and galaxy evolution based on these results.

• Nuclear Engineering and Technology
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• 제48권1호
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• pp.236-245
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• 2016

In a reactor coolant system of a nuclear power plant (NPP), an overpressure protection system keeps pressure in the loop within 110% of design pressure. However if the system does not work properly, pressure in the loop could elevate hugely in a short time. It would be seriously disastrous if a weak point in the pressure boundary component bursts and releases radioactive material within the containment; and it may lead to a leak outside the containment. In this study, a gross deformation that leads to a burst of pressure boundary components was investigated. Major components in the primary pressure boundary that is structurally important were selected based on structural mechanics, then, they were used to study the burst pressure of components by finite element method (FEM) analysis and by number of closed forms of theoretical relations. The burst pressure was also used as a metric of design optimization. It revealed which component was the weakest and which component had the highest margin to bursting failure. This information is valuable in severe accident progression prediction. The burst pressures of APR-1400, AP1000 and VVER-1000 reactor coolant systems were evaluated and compared to give relative margins of safety.

• 한국환경보건학회지
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• 제37권3호
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• pp.193-200
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• 2011

Objective: The purpose of this study is to compare and analyze the level of exposure to volatile organic compounds for different kinds of households in apartments or houses and analyze the relation between atopy-related symptoms and concentration of volatile organic compounds in order to improve indoor air quality and start to build a process to prevent environmental diseases. Method: From July 2010 to November 2010, TVOC concentration levels were measured and analyzed in 402 general households and 236 weak households, totalling 638 households. Residents were asked to fill out a survey on environmental disease. All resources were analyzed using SPSS 12.0 program. Result: In comparing the differences in concentration levels of volatile organic compounds for different types of households, including existing apartments and houses, the type of housing did not affect the concentration level of volatile organic compounds, but the relevance with skin trouble, diagnosed atopy, and atopy systems all had statistical similarities. Moreover, above-limit volatile organic compounds showed statistical relevance with amount of ventilation, time of construction, skin trouble, diagnosed atopy and atopy symptoms. Conclusion: The study concludes that as the time of construction recedes further into the past and as the amount of ventilation is higher, the exposure level to volatile organic compounds was lower and the group that were suffering from atopy symptoms had higher exposure to volatile organic compounds.