• 한국생물공학회:학술대회논문집
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• 2003.10a
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• pp.356-358
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• 2003

The use of cultured epidermal sheet grafts for large full-thickness wound has been tempered by weak points such as long culture periods, difficulty in handling the fragile sheets, high costs and the detachment of the skin cells from the culture dishes by enzymatic digestion. To overcome the drawback of epidermal sheet grafts, we have developed a transplantation method to spray the cultured human keratinocytes with the mixtures of rhEGF and fibrin gel matrix to the full-thickness wounds on the dorsum of the athymic mice to regenerate epithelial layers. Wound biopsies were retrieved at 7, 14 and 21 days after transplantation and retrieved biopsies were analyzed by histology and immunohistochemistry. Transplanted keratinocytes and EGF-fibriin gel accelerated wound regeneration compared with control groups. The technique developed in this study overcomes the drawbacks of the current cultured epidermal sheet grafts and accelerates epidermal wound healing.

• Journal of Environmental Science International
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• v.11 no.1
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• pp.41-56
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• 2002

In order to estimate the quantitative roles of the tide induced residual currents, density currents and wind driven currents on the residual currents in Kwangynag Bay Korea, numerical experiments with a diagnostic multi-level model were carried out. Density currents were calculated from the temperature and salinity data observed in January, May, August and November 1998. Anti-clockwise circulations are formed at the western inner part of the bay, the location from the east of Myodo Is. to the south of POSCO Co. and the place between Yeosu peninsula and Namhae Is. from the calculation results of the tide induced residual currents. Velocities of the density currents are less than 3cm/s at the western inner part of the bay and about 5cm/s at the southern entrance of the bay. Density currents get strong in summer and weak in autumn. Wind driven currents at the surface layer flow in the directions of the given winds which are the daily mean winds when the temperature and salinity observations are carried out. In the middle and lower layers, however the wind driven currents flow in the opposite direction to the surface currents as supplementary currents. The surface wind driven currents are greater than the tide induced residual currents or the density currents. The calculated residual currents including the tide induced residual currents, density currents and wind driven currents agree with the results of the current observations approximately. In the Bay, the wind driven currents affect on the residual currents greatestly and tide induced residual currents and density currents do in the second place and the third place.

• Journal of the Korean Geosynthetics Society
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• v.8 no.4
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• pp.27-34
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• 2009

In this paper, characteristics of shear strength and deformation of geosynthetics-reinforced slag materials are described. In order to investigate the effect of geosynthetics on shear strength and deformation behavior of slags, when they are reinforced with geosynthetics or geomat such as PET mat, large triaxial tests were performed under consolidated-drained condition. The materials used in the study are real ones as they are in the field, so that the scale effect of samples disappeared. From the large triaxial tests, it was observed that the stress-strain relationship of geosynthetics-reinforced slags shows relatively small dilatancy and weak tendency of strain hardening, compared with that of slags without reinforcement. The shear strength parameters such as apparent cohesion and internal friction angle increase with PET mat reinforcement, consequently result in about 1.2 (for low confining pressure) to 1.4 (for high confining pressure) times of shear strength of un-reinforced sample. Therefore, the adoption of geomat-reinforced slag layers leads to an increase in the factor of safety for embankment design on soft soil formations.

• Geotechnical Engineering
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• v.14 no.4
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• pp.91-102
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• 1998

Electrical resistivity method, one of the most widely used geophysical prospecting methods. has been usually applied to explorations for groundwater and underground resources. However, it has been extending its scope to civil & environmental engineering areas since it twas been developed so as to image underground structures effectively. A FEM algorithm for the dipole-dipole array was developed to correct topographic effects which have a serious influence on electrical methods. Applicability of the electrical resistivity imaging technique to civil & environmental engineering areas was verified through three case histories in this study First, thickness of soil layers was profiled to judge the possibility of developing borrow-pits tn an industrial complect site. Second, weak zones such as fractures and coal seams were detected to provide geological information for design and construction in a high mountain tunnel site. Third, horizontal/vertical distribution of the contaminated zone and depth of waste disposal were delineated in a completed industrial waste disposal site.

• Journal of the Korean Chemical Society
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• v.22 no.2
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• pp.86-94
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• 1978

The crystal and molecular structure of theophylline hydrochloride has been determined from X-ray data by Patterson techniques. The structure has been refined by block-diagonal least-squares and Fourier synthesis on three dimensional data. The unit cell is orthorhombic, space group $P_{na21}$, with a = 14.01, b = 11.49, c = 6.77${\AA}$, and contains four molecules. The final R value based on 743 observed reflexions is 12.2%. The intramolecular distances are similar to those in other compounds containing a purine or pyrimidine group. The molecules are nearly planar and are stacked in layers parallel to the (001)plane. The chlorine atom is coordinated to N(1) atom at a distance of 3.06${\AA}$. The structure is stabilized mainly by van der Waals interactions; however, a short N${\cdot}{\cdot}{\cdot}$Cl contact of length $3.06\AA$, which is slightly less than the expected van der Waals separation, suggest that weak charge transfer interaction may be present. The relationship between this structure and the known structures of theophylline monohydrate and caffeine monohydrate are discussed.

• Journal of the Korean Vacuum Society
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• v.19 no.1
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• pp.58-65
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• 2010

AlN thin films were deposited on sapphire substrates and ZnO templates by rf-magnetron sputtering. Powder-sintered AlN target was adopted for source material. Thickness of AlN layer was linearly dependent on plasma power from 50 to 110 W, and it decreased slightly when working pressure increased from 3 to 10 mTorr due to short mean free path of source material sputtered from AlN target by Ar working gas. When $N_2$ gas was mixed with Ar, the thickness of AlN layer decreased significantly because of low sputter yield of nitrogen. AlN layer was also deposited on ZnO template. However, it showed weak thermal stability that the interface between AlN and ZnO was deteriorated by rapid thermal annealing treatment above $700^{\circ}C$. In addition, ZnO layer was largely attacked by MOCVD ambient gas of hydrogen and ammonia around $700^{\circ}C$ through inferior AlN layer deposited by sputtering. And AlN layers were fully peeled off above $900^{\circ}C$.

• Journal of the Mineralogical Society of Korea
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• v.14 no.2
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• pp.119-127
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• 2001

FTIR spectroscopic study was undertaken on dickite and pyrophyllite with Si and Al cations in the far-infrared(Far-IR) and mid-infrared (Mid-IR) regions, respectively. Attempts were made to present bonding information and make assignments on the absorption bands of dickite in the Far-IR region. Dickites contain a small proportions or kaolinite or nacrite layers. FTIR can be used as a potential tool for characterizing the presence of mixed-layer with different polytypes of the kaolin minerals. There is no clear relationship between Hinckley index and crystallinity of dickite. Although pyrophyllite shows a strong OH stretching band at 3673-3676 $cm^{-1}$ / corresponding to an inner hydroxyl group, the weak band at $3645-3648 cm^{-1}$ seems to be due to the symmetric vibration if the symmetry of the structure is not ideal, probably due to the presence of trace Fe or mixture phases of 1Tc and 2M polytypes.

• Journal of Korean Society of Water and Wastewater
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• v.30 no.1
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• pp.19-31
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• 2016

The Saemangeum watershed is required to manage water pollution effectively but the effect of liquid manure (LM) on soil and water quality in the basin is not clearly identified as yet. This study aims at assessing the effect on soil of a rice field and water quality of water bodies near the rice field during rice-crop time period to find out the effect of LM, the effect of rainfall, and the effect of rice-crop environment on soil and water quality by analyzing data of nitrogen components. As a result of the LM distribution, $NO_3-N$ was much higher than other N components in the entire soil layers and it was accelerated by rainfall right after the LM distribution. Compared to chemical fertilizer (CF), LM was slightly affected but still influenced on the surface water quality. During weak rainfall, low nitrogen concentration in topsoil was resulted as NH3-N decreased and Org-N and $NO_3-N$ increased. $NO_3-N$ concentration in the water of irrigation canals increased with time. During intensive rainfall, $NO_3-N$ and Org-N of the soil were measured highly in the submerged condition, while the water quality of the rice field was lower due to flooding into the irrigation canal as well as the growth of the rice plants. Also, total nitrogen was increased more than 7 times and it showed serious water quality deterioration due to LM and excessive fertilizer distribution, and rainfall during all rice-crop processes. The effect of LM on water quality should be studied consistently to provide critical data while considering weather condition, cropping conditions, soil characteristics, and so on.

• Proceedings of the Korean Geotechical Society Conference
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• 2009.09a
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• pp.1372-1377
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• 2009

For the remediation of the subsurface contaminated by nonaqueous phase liquids(NAPLs), it is important to characterize the NAPL zone properly. Conventional characterization methods provide data at discrete points. To overcome the weak points of conventional characterization methods, the partitioning tracer method has been developed and studied. The average saturation of NAPL($S_n$), which is the representative and continuous saturation value within contaminated site, can be calculated by comparing the transport of the partitioning tracers to that of the conservative tracer in the partitioning tracer method. In this study, the application of the partitioning tracer method in heterogeneous media was investigated. To represent the heterogeneous condition of subsurface, a two-dimensional soil box was divided into four layers and each layer contained different sized soils. Soils in the soil box were contaminated by the mixture of kerosene and diesel, and partitioning tracer tests were conducted before and after the contamination using methanol as conservative tracer and 4-methyl-2-pentanol, 2-ethyl-1-butanol, and hexanol as partitioning tracers. The response curves of partitioning tracers from contaminated soils were separated and retarded in comparison with those from non-contaminated soils. The contamination of soils by NAPLs, therefore, can be detected by partitioning tracer method considering these retardations of tracers. From our experiment condition, the average saturation of NAPLs calculated by partitioning tracer method using the methanol as conservative tracer and hexanol as partitioning tracer showed the highest accuracy, though all results were underestimated. Further studies, therefore, were needed for improving the accuracy using the partitioning tracer test in heterogeneous media.

• Computational Structural Engineering
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• v.7 no.4
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• pp.57-67
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• 1994

It is usual that underground structures are constructed within a multi-layered medium. In this paper, an efficient numerical modelling of multi-layered structural systems is studied using coupled analysis of finite elements and boundary elements. The finite elements are applied to the area in which the material nonlinearity dominates, and the boundary elements are applied to the far field where the nonlinearity is relatively weak. In the boundary element modelling of the multi-layered medium, fundamental solutions are not readily available. Thus, methods which can utilize existing Kelvin solutions are sought for the interior multi-layered domain problem. The interior domain problem which has piecewise homogeneous layers is analyzed using boundary elements with Kelvin solution, by discretizing each homogeneous subdomain and enforcing compatibility and equilibrium conditions between interfaces. Developed methodology is verified by comparing its results with those from the finite element analysis and it is concluded that coupled analysis using boundary elements and finite elements can be reasonable and efficient.