• YAKHAK HOEJI
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• v.35 no.5
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• pp.384-388
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• 1991

To explore the effect of monosodium-L-glutamate(MSG) on CCI$_{4}$-damaged liver in Wister male rat, 5% MSG solution as drink water were administered after S.C. injection of 0.1 mg/kg CC1$_{4}$ twice a week for 4 weeks. After last administration of MSG, heptic glutathione(GSH) dependent system was assayed. It showed that MSG increased significanly hepatic glutathione(GSH) and glutathione peroxidase(GSH$_{px}$), but decreased glutathione-S-transferase(GST) acivity in normal rats. MSG increased significantly the GSH$_{px}$ and GST activities in rats with CCI$_{4}$-induced liver damage. These results indicate that decrease of GSH dependent systems in CC1$_{4}$ liver injury might be partially elevated by coadministration of MSG.

• YAKHAK HOEJI
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• v.54 no.1
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• pp.67-74
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• 2010

Some of the benzopyrene (BP)-DNA adduct are known to build intercalated motif between flanking base pairs in damaged DNA depending on the structural condition. The size of benzopyrene itself is definitely not comparable with any of the DNA bases and thus the question whether the lesion of some base pair by insertion of benzopyrene can happen with or without a dramatic distortion of the helical structure is a highly interesting theme. In this work we used a molecular dynamics simulation based on the theory of molecular mechanics. The specific consequences about the structural properties of the intercalated structures and benzopyrene motif in minor groove of the double helix are deduced after 5 ns simulation time.

• Journal of the Korea institute for structural maintenance and inspection
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• v.1 no.1
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• pp.125-132
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• 1997

This study was intended to investigate the effects of epoxy grout on compressive strength for damaged concrete structures. For this purpose, concrete molds were manufactured and tested for compressive strength at 28 days after water curing. Two kinds of Korea-made and one Japan-made epoxy grouts were injected into the broken concrete molds with the automatic low-pressure injecting method or the hand injecting method.

• 한국방재학회:학술대회논문집
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• 2008.02a
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• pp.229-232
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• 2008

The Central East Sea Tsunami caused huge damage to the eastern coast of the Korean Peninsula, eapecially Imwon port was damaged relatively strongly beacause of water depth variation which makes the wave concentration on this port. there are many virtual tsunami in east sea which has a possibility of happening. So, it is very important to expect the region which may be damaged by vritual tsunmis. In this study, modified dispersion-correction terms are used. The modified scheme has the advantage of using the constant spatial grid size and time step size even in real topography. Dynamic linking technique and staggered grid system are used. Using this model some cases of virtual tsunami was simulated and check the region which is occured maximum wave heights on the eastern sea of the Korean peninsula.

• Journal of Veterinary Clinics
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• v.25 no.6
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• pp.466-470
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• 2008

The purpose of this study is to investigate whether the effects of topically applied petrolatum and glycerin on the barrier repair of acetone-induced skin damage in 6 beagle dogs. To confirm the effects of petrolatum and glycerin on acetone disrupted skin models, we performed to evaluate the characteristics of transepidermal water loss and SC hydration and scanning electron microscopic observations. TEWL and SC hydration measurements were carried out 3, 6, 12, 24, 48h after applying petrolatum and glycerin during recovery from acute disruption. Our results showed that there were some different effects between petrolatum and glycerin on the acetone damaged skin such as barrier function repair process and SC hydration status. The results indicate that the significant improvement could be observed in glycerin apply more than petrolatum after acetone damages, and further study will be required.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2020.06a
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• pp.167-168
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• 2020

In this study, we attempted to present a method for diagnosing the depth of the early frost damage concrete using organic pigments under the cold weather. As a result, it is considered that the organic pigment did not penetrate into the voids of the concrete that had been damaged by the early frost damage and only the surface was adhered. Therefore, when fine particles that can be melted in water and pass through voids are used, it is analyzed that it can penetrate damaged part of the concrete.

• Proceedings of the Korean Geotechical Society Conference
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• 2010.09c
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• pp.3-10
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• 2010

Case study was carried out on the interpretation of the mechanical behavior of a severely damaged reinforced earth wall comprising geotextile with the concrete panel facing. In this part I, the outline of the damaged reinforced earth wall is in detail described. The background and cause of the damage are discussed based on the results of site investigation. The engineering properties of the fill were examined by performing various in-situ and laboratory tests, including the surface wave survey (SWS), PS-logging, RI-logging, soaking test, the direct shear box (DSB) test, bender element (BE) test, etc. The background as well as the cause for the damage of the wall may be described such that i) a considerable amount of settlement took place over a 3m thick weak soil layer in the lower part of the reinforced earth due to seepage of rainfall water, ii) the weight of the upper fill was partially supported by the geo-textile hooked on the concrete panels (n.b., named conveniently "hammock state" in this paper), and iii) the concrete panels to form the hammock were severely damaged by the unexpectedly large downwards compression force triggered by the tension force of the geotextile. The numerical simulation for the hammock state of the wall, together with counter-measures to re- stabilize the wall is subsequently described in Part II.

• Journal of the Korean Society of Marine Environment & Safety
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• v.28 no.2
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• pp.394-405
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• 2022

This paper presents the numerical estimation results of oil outflows from damaged single-hull and double-hull ships by using computational fluid dynamics (CFD) simulations. A CFD method for multi-phase flow analysis was used, and the effects of numerical parameters on oil flows was investigated. Numerical simulations were conducted to predict the changes in oil outflows under various damage conditions owing to grounding or collision accidents and verified through available experimental results. The present numerical results showed a good agreement with the experimental results according to the geometrical characteristics of single and double hulls. In particular, the oil outflows from double hulls accompanying complex interactions between water and oil were reasonably predicted a shown in the experiment. This study established a reliable CFD technique necessary for estimating the oil outflows of damaged ships.

• Journal of the Korean Society of Food Science and Nutrition
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• v.14 no.2
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• pp.145-150
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• 1985

This study was conducted to examine the pharmacological effect of water soluble extract of Lichens (Parmelia, Physcia and Cladonia species) on liver-damaged rat by $CCl_4$ injection. Rat livers were damaged acutely and chronically by one-time injection of $CCl_4$ just prior to five days of experimental period and continuous injections in every three days for eight weeks of experimental period, respectively. During each period the experimental group was fed Lichens extract(5.5 mg of dry wt/ml) instead of water given to the control group. For both acute and chronic liver damage, the experimental group showed higher oxidative activity of hepatic mitochondria measured by state 3 respiration, P/O ratio, respiratory control and ATP synthesized, compard to the control group. Serum glucose was slightly higher in the experimental group but liver glycogen showed no significant difference between experimental and control groups. In experimental group, liver glucose-6-phosphatase activity was increased during first two days after acute liver damage, but not significantly different from control group during chronic damage. Liver lactate, malate plus fumarte and glutamate tended to be higher in the experimental group, especially for chronic liver damaged rat. It is concluded that Lichens extract stimulate cytoplasmic and mitochondrial oxidative activities and the possible mechanism of the latter is supposed to involve the preservation of membrane integrity by certain component(s) of water-soluble Lichens extract.

• Proceedings of the Korea Concrete Institute Conference
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• 2003.11a
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• pp.577-580
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• 2003

Problem of repairing by boring is that it deteriorates stabelety and durability of structure by permeation of seawater from underneath after damage and repair of reinforcing rod regarding of spot. The purpose of this study is to improve the porblem by using the repair method of general boring to mend the of large mat basis. Direction of thes experiment is to apply the new repair material and the method to control the blazing fire factor caused by the crack from the foundation of large mat and also to estimate it's integrity. New method of construction is method of contruction that do speace scurity in vertical drilling and bottom useing water jet. New material used bantonite and rubberized asphalt. Test result existent repair method of construction large size mat basis perforation is difficult and reinforcing rod can be damaged coule there were a lot of problems with re-water leakage of crack repair region, but overcomes existent short coming by method that apply in this study.