• Title/Summary/Keyword: warm storage

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Clinical study of 1 case of patient with Hypothyroidism (갑상선(甲狀腺) 기능저하증(機能低下症) 환자(患者) 1례(例)에 대(對)한 임상적(臨床的) 고찰(考察))

  • Kim, Yong-Sung;Kim, Kyung-Su
    • Herbal Formula Science
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    • v.9 no.1
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    • pp.397-403
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    • 2001
  • Tyroid gland is the biggist endocrine organ which is located in front of trochea. The role of the thyroid gland in the total body economy comprises the synthesis, storage, and secretion of thyroid hormones, which are necessary to growth, development, and normal bodymetabolism. Hypothyroidism is the state of a dificiency in the secretion of Thyroid hormone. This may result from idiopathic myxedema, or distruction or removal of thyroid, or goiter, or thyroid adenomas. Hypothyroidism corresponds to thick lips, dry skin, puffy eyelids, coars hair, megaloglossia, and pudgy hands etc. On one case of Hypothyroidism who was hospitalized for the chief complaints of fatigue, general weakness, coldness, edema in head, neck site, lumbago. I diagnosed this case as dificiency of Qi and blood(氣血兩虛) or dificiency of warm-Qi in spleen and kidney(脾腎陽虛). And then I used Moxa treatment to increase Qi and blood, and Acupuncture treatment to reduce shoulder and neck pain, lumbago. And Herb-med is used to increase Qi and blood, and recover of general condition. As a result, this patient got better more quickly.

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Preparation and Evaluation of Solid lipid Microspheres Containing Cyclosporine A (사이클로스포린을 함유한 고형 지질미립구의 제조와 평가)

  • 양수근;박준상;최영욱
    • YAKHAK HOEJI
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    • v.39 no.5
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    • pp.487-494
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    • 1995
  • Solid lipid microspheres (SLMs) were prepared using various lipids and solidifying agents, in order to enhance the gastrointestinal absorption of Cyclosporine A (Cs A) which is a practically water-insoluble drug with low systemic bioavailability. Egg lecithin and HCO-60 (polyoxyethylated 60 mol, hydrogenated castor oil) were used as lipids. Stearic acid and stearyl alcohol were used as solidifying agents. Emulsion concentrates containing Cs A were prepared by mixing the melted lipid and solidifying agent with water, employing bile salts as a cosurfactant. SLMs were obtained by dispersing the warm emulsion concentrate in cold distilled water under mechanical stirring, followed by freeze drying. Physical characteristics of each SLM were investigated by particle size analysis, optical microscopy and scanning electron microscopy. Mean particle size of SLMs was in the range of 30 to 40.mu.m. The SLMs were in good appearance with spherical shape before freeze drying, but were deformed partially after freeze drying. Drug loading efficiencies of SLMs were observed as high as 80 to 90% in average. The systemic bioavailability of Cs A from different SLM formula was investigated in rats following oral administration. Cs A in whole blood was extracted and assayed by HPLC. SLMs revealed the higher bioavailabilities than the standard formula based on the marketed product. SLMs might have several advantages over standard formula for enhanced gastrointestinal absorption, controlled release properties, high loading capacity of the water-insoluble drug, and feasibility of solid dosage forms with better stability in storage.

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Effects of hydrogen peroxide pretreatment and heat activation of silane on the shear bond strength of fiber-reinforced composite posts to resin cement

  • Pyun, Jung-Hoon;Shin, Tae-Bong;Lee, Joo-Hee;Ahn, Kang-Min;Kim, Tae-Hyung;Cha, Hyun-Suk
    • The Journal of Advanced Prosthodontics
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    • v.8 no.2
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    • pp.94-100
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    • 2016
  • PURPOSE. To evaluate the effects of hydrogen peroxide pretreatment and heat activation of silane on the shear bond strength of fiber-reinforced composite posts to resin cement. MATERIALS AND METHODS. The specimens were prepared to evaluate the bond strength of epoxy resin-based fiber posts (D.T. Light-Post) to dual-curing resin cement (RelyX U200). The specimens were divided into four groups (n=18) according to different surface treatments: group 1, no treatment; group 2, silanization; group 3, silanization after hydrogen peroxide etching; group 4, silanization with warm drying at $80^{\circ}C$ after hydrogen peroxide etching. After storage of the specimens in distilled water at $37^{\circ}C$ for 24 hours, the shear bond strength (in MPa) between the fiber post and resin cement was measured using a universal testing machine. The fractured surface of the fiber post was examined using scanning electron microscopy. Data were analyzed using one-way ANOVA and post-hoc analysis with Tukey's HSD test (${\alpha}=0.05$). RESULTS. Silanization of the fiber post (Group 2) significantly increased the bond strength in comparison with the non treated control (Group 1) (P<.05). Heat drying after silanization also significantly increased the bond strength (Group 3 and 4) (P<.05). However, no effect was determined for hydrogen peroxide etching before applying silane agent (Group 2 and 3) (P>.05). CONCLUSION. Fiber post silanization and subsequent heat treatment ($80^{\circ}C$) with warm air blower can be beneficial in clinical post cementation. However, hydrogen peroxide etching prior to silanization was not effective in this study.

Anaerobic Biotreatment of Animal Manure - A review of current knowledge and direction for future research -

  • Hong, Jihyung
    • Journal of Animal Environmental Science
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    • v.11 no.2
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    • pp.97-102
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    • 2005
  • Anaerobic decomposition is one of the most common processes in nature and has been extensively used in waste and wastewater treatment for several centuries. New applications and system modifications continue to be adapted making the process either more effective, less expensive, or suited to the particular waste in question and the operation to which it is to be applied. Animal manure is a highly biodegradable organic material and will naturally undergo anaerobic fermentation, resulting in release of noxious odors, such as in manure storage pits. Depending on the presence or absence of oxygen in the manure, biological treatment process may be either aerobic or anaerobic. Under anaerobic conditions, bacteria carry on fermentative metabolisms to break down the complex organic substances into simpler organic acids and then convert them to ultimately formed methane and carbon dioxide. Anaerobic biological systems for animal manure treatment include anaerobic lagoons and anaerobic digesters. Methane and carbon dioxide are the principal end products of controlled anaerobic digestion. These two gases are collectively called biogas. The biogas contains $60\~70\%$ methane and can be used directly as a fuel for heating or electrical power generation. Trace amounts of ammonia and hydrogen sulfide ($100\~300\;ppm$) are always present in the biogas stream. Anaerobic lagoons have found widespread application in the treatment of animal manure because of their low initial costs, ease of operation and convenience of loading by gravity flow from the animal buildings. The main disadvantage is the release of odors from the open surfaces of the lagoons, especially during the spring warm-up or if the lagoons are overloaded. However, if the lagoons are covered and gases are collected, the odor problems can be solved and the methane collected can be used as a fuel. Anaerobic digesters are air-tight, enclosed vessels and are used to digest manure in a well-controlled environment, thus resulting in higher digestion rates and smaller space requirements than anaerobic lagoons. Anaerobic digesters are usually heated and mixed to maximize treatment efficiency and biogas production. The objective of this work was to review a current anaerobic biological treatment of animal manure for effective new technologies in the future.

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Depositional Landforms in Jiwoo Drainage Basin (지우천 유역의 퇴적지형 연구)

  • Oh, In-Sun
    • Journal of the Korean association of regional geographers
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    • v.15 no.2
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    • pp.192-203
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    • 2009
  • The purpose of this paper is to elucidate the formative processes of depositional landforms in Jiwoo drainage basin which located in the most upstream reach of Namgang River. Through the analysis of morphologic characteristics and sedimentary facies, the formative processes can be summarized as follow: First, the high depositional landforms(Sapyeong, Eungam, Naedongdyttle site) were formed by gelifluction process in the periglacial environment during the last glacial period. And the relative height over river bed of them is getting lower from upper to downstream. The extent of the high depositional landforms is assumed about 1 kilometer downstream far from the confluence of Jiwoo stream and Namgang River. Second, the sediments in the gentle slope at Jangseungbuldle were carried by gelifluction process during the last glacial stage after the deep-weathered bedrock had formed a gentle slope. Third, the high depositional landforms were dissected during warm and humid environment of postglacial stage, and some sediments of them were left in the river bed. Later, as the more upstream high depositional landforms were dissected completely, stream power was getting more than resistance(sediment storage) and the low depositional landforms(Sapyeong, Yongchusa, Deungbangdle site) were formed.

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A Study on the Seed Germination and Seedling Density of Fraxinus mandshruica in Nursery (포지(圃地)에 있어서 들메나무의 종자발아(種字發芽) 및 묘목생육밀도(苗木生育密度)에 관한 연구(研究))

  • Chung, Seung Ho;Kim, Jong Won;Lee, Geun Soo
    • Journal of Korean Society of Forest Science
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    • v.63 no.1
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    • pp.9-11
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    • 1984
  • This study was carried out to compare the seed germination and seedling growth of Fraxinus mandshurica growing in natural forests of the interior of Korea. Three stimulation methods were used for germination and the seedlings were planted with various densities. The results obtained were summarized as follows: 1) It was suggested that the 80 seedlings per square meter were proper densities for their growth at a nursery bed. 2) Among the three stimulation methods, 19.9% of germination was shown by the moisture storage, 2.3% by cold and warm stratification, and 0.4% by cold stratification. 3) The 8.1% of the total seedlings showed secondary height growth.

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A Study on Interactive Talking Companion Doll Robot System Using Big Data for the Elderly Living Alone (빅데이터를 이용한 독거노인 돌봄 AI 대화형 말동무 아가야(AGAYA) 로봇 시스템에 관한 연구)

  • Song, Moon-Sun
    • The Journal of the Korea Contents Association
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    • v.22 no.5
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    • pp.305-318
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    • 2022
  • We focused on the care effectiveness of the interactive AI robots. developed an AI toy robot called 'Agaya' to contribute to personalization with more human-centered care. First, by applying P-TTS technology, you can maximize intimacy by autonomously selecting the voice of the person you want to hear. Second, it is possible to heal in your own way with good memory storage and bring back memory function. Third, by having five senses of the role of eyes, nose, mouth, ears, and hands, seeking better personalised services. Fourth, it attempted to develop technologies such as warm temperature maintenance, aroma, sterilization and fine dust removal, convenient charging method. These skills will expand the effective use of interactive robots by elderly people and contribute to building a positive image of the elderly who can plan the remaining old age productively and independently

Application of High Resolution Multi-satellite Precipitation Products and a Distributed Hydrological Modeling for Daily Runoff Simulation (고해상도 다중위성 강수자료와 분포형 수문모형의 유출모의 적용)

  • Kim, Jong Pil;Park, Kyung-Won;Jung, Il-Won;Han, Kyung-Soo;Kim, Gwangseob
    • Korean Journal of Remote Sensing
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    • v.29 no.2
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    • pp.263-274
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    • 2013
  • In this study we evaluated the hydrological applicability of multi-satellite precipitation estimates. Three high-resolution global multi-satellite precipitation products, the Tropical Rainfall Measuring Mission (TRMM) Multi-satellite Precipitation Analysis (TMPA), the Global Satellite Mapping of Precipitation (GSMaP), and the Climate Precipitation Center (CPC) Morphing technique (CMORPH), were applied to the Coupled Routing and Excess Storage (CREST) model for the evaluation of their hydrological utility. The CREST model was calibrated from 2002 to 2005 and validated from 2006 to 2009 in the Chungju Dam watershed, including two years of warm-up periods (2002-2003 and 2006-2007). Areal-averaged precipitation time series of the multi-satellite data were compared with those of the ground records. The results indicate that the multi-satellite precipitation can reflect the seasonal variation of precipitation in the Chungju Dam watershed. However, TMPA overestimates the amount of annual and monthly precipitation while GSMaP and CMORPH underestimate the precipitation during the period from 2002 to 2009. These biases of multi-satellite precipitation products induce poor performances in hydrological simulation, although TMPA is better than both of GSMaP and CMORPH. Our results indicate that advanced rainfall algorithms may be required to improve its hydrological applicability in South Korea.

A model of Isolated Renal Hemoperfusion (허혈/재관류 손상연구를 위한 체외 신장 재관류 모델)

  • Nam, Hyun-Suk;Woo, Heung-Myong
    • Journal of Veterinary Clinics
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    • v.26 no.5
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    • pp.441-444
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    • 2009
  • Ischemia-reperfusion (I/R) injury is associated with an increased risk of acute rejection, delayed graft function and long-term changes after kidney transplantation. The reperfusion models remain unsolved complications such as vascular obstruction and blood leakage. We developed an alternative model of isolated hemoperfusion in porcine kidneys. In the present study we introduced a newly developed reperfusion method. A connector was used instead of surgical suture for the vascular anastomosis on the inguinal region in which main femoral vessels are parallel and big enough to perfuse the kidney. To assess renal perfusion quality of the modified hemoreperfusion model, we analyzed both hemodynamic values and patterns of I/R injury following a renal reperfusion. Following unilateral nephrectomy, the kidneys were preserved for 0, 24 and 48 hours at $4^{\circ}C$ with histidine-tryptophan ketogluatarate (HTK) solution and reperfused for 3 hours by vascular anastomosis connected to the femoral artery and vein in inguinal region. Histolopathological examinations were assessed on kidney biopsy specimens, taken after each cold storage and reperfusion. No differences of hemodynamic values were observed between aorta and femoral artery. The average warm ischemia time before reperfusion start was $7.0{\pm}1.1$ minutes. There were no complications including vascular obstruction and blood leakage during the reperfusion. I/R injury of the perfused kidneys in this model was dependent upon the cold ischemia time. The results support that the modified perfusion model is simple and appropriate for the study of early renal I/R injury and transplant immunology.

Effects of Gibberellin Treatment on the Dormancy-breaking and Germination Promotion of Carpinus laxiflora Seeds Stored for 16 Years (지베렐린 처리에 따른 서어나무 16년 저장 종자의 휴면타파 및 발아촉진 효과)

  • Han, Sim-Hee;Ku, Ja Jung;Kim, Du Hyun;Lim, Hyo-In
    • Journal of Korean Society of Forest Science
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    • v.108 no.4
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    • pp.531-539
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    • 2019
  • This study assessed the vitality of Carpinus laxiflora seeds stored for more than 15 years in order to discover optimal pre-treatment conditions for removingthe causes of seed dormancy and improving revitalization rate. Seeds were collected in October 2000 and stored at -18℃ for 16 years. Experiments to assess the revitalization ability of the seeds were performed under the following conditions: a controlled environment; in warm stratification (30 days at 23℃); in cold stratification (30 days at 4℃ andfor 30, 45, 60, and 120 days); gibberellin (GA3) treatment (24 hours per day in GA3 solutions of 100, 500, 1000, 2000, and 3000 mg·L-1); and both cold stratification and GA3 treatment (30 days at 4℃, then in a GA3 solution of 100, 500, and 1000 mg·L-1 for 2 hours). The average germination percentage(GP) of untreated seeds was 2%, and the average GP of warm-stratification seeds was 10%. Cold-stratification seeds had the highest GP at 81% for the 45-day process, while the 120-day cold-stratification seeds had the lowest GP at 67.3%. The average GP of seeds treated with GA3 ranged from 77% (100 mg·L-1) to 99% (1000 mg·L-1), indicatingsignificant differences between the treatment concentrations. The treatment effect of GA3 was highest at 500 mg·L-1 and 1000 mg·L-1, and lowest at 100 mg·L-1. The average GP of seeds treated with GA3 following cold stratification was 68%, which was lower than the cold stratification-only (73.2%) and GA3-only (88.4%) treatments. A comprehensive comparison of the seed germination characteristics according to the four treatments determined that a GA3 500 mg·L-1 pre-treatment, with the highest average GP, was ideally suited to the revitalization of long-term stored C. laxiflora seeds. Consequently, C. laxiflora stored at -18℃ for 16 years indicated strong vitality and could be regenerated by proper pre-treatment.