• Title/Summary/Keyword: vulnerable populations

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Effects of GR89696 on parvalbumin positive neurons after cerebral ischemia in the Mongolian gerbil (몽고리안 저빌에서 뇌허혈시 GR89696이 parvalbumin 발현 신경세포에 미치는 영향)

  • Kwon, Young-bae;Yang, Il-suk;Lee, Jang-hern
    • Korean Journal of Veterinary Research
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    • v.39 no.1
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    • pp.34-44
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    • 1999
  • Ischemic damage in the selectively vulnerable populations of neurons is thought to be caused by an abnormal accumulation of intracellular calcium. It has been reported that the neurons, expressing specific calcium binding proteins, might effectively control intracellular calcium concentrations because of a high capacity to buffer intracellular calcium in the brain ischemic condition. It is uncertain that parvalbumin, one of the calcium binding proteins, can protect the neurons from the cerebral ischemic damage. Recently, treatment of kappa opioid agonists increased survival rate, improved neurological function, and decreased tissue damage under the cerebral ischemic condition. Many evidences indicate that these therapeutic effects might result from regulation of calcium concentration. This study was designed to analyze the changes of number in parvalbumin-positive neurons after cerebral ischemic damage according to timepoints after cerebral ischemic induction. In addition, we evaluated the effect of GR89696 (kappa opioid agonist) or naltrexone(non selective opioid antagonist) on the changes of number in parvalbumin expressing neurons under ischemic condition. Cerebral ischemia was induced by occluding the common carotid artery of experimental animals. The hippocampal areas were morphometrically analyzed at different time point after ischemic induction(1, 3, 5 days) by using immuno-histochemical technique and imaging analysis system. The number of parvalbumin-positive neurons in hippocampus was significantly reduced at 1 day after ischemia(p<0.05). Furthermore, the number of parvalbumin-immunoreactive neurons was dramatically reduced at 3 and 5 days after cerebral ischemic induction(p<0.05) as compared to 1 day group after ischemia, as well as sham control group. Significant reduction of parvalbumin positive neurons in CA1 region of hippocampus was observed at 1 day after cerebral ischemic induction. However, significant loss of MAP2 immunoreactivity was observed at 3 day after cerebral ischemia. The loss of parvalbumin-positive neurons and MAP2 immunoreactivity in CA1 region was prevented by pre-administration of GR89696 compared to that of saline-treated ischemic group. Furthermore, protective effect of GR89696 partially reversed by pre-treatment of naltrexone. These data indicate that parvalbumin-positive neurons more sensitively responded to cerebral ischemic damage than MAP2 protein. Moreover, this loss of parvalbumin-positive neurons was effectively prevented by the pretreatment of kappa opioid agonist. It was also suggested that the changes of number in parvalbumin-positive neurons could be used as the specific marker to analyze the degree of ischemic neuronal damage.

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Distribution Aspect and Extinction Threat Evaluation of the Endangered Species, Rhodeus pseudosericeus (Pisces: Cyprinidae) in Korea (멸종위기어류 한강납줄개 Rhodeus pseudosericeus (Pisces: Cyprinidae)의 분포양상 및 멸종위협 평가)

  • Ko, Myeong-Hun;Han, Mee-Sook;Kwan, Sun-Man
    • Korean Journal of Ichthyology
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    • v.30 no.2
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    • pp.100-106
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    • 2018
  • The distribution aspect and extinction threat evaluation of the endangered species, Rhodeus pseudosericeus were investigated from 2012 to 2017 in Korea for the subject of this study. The number of appearance sites in the past literature of available and identified R. pseudosericeus was 26. During the study period, the samples of R. pseudosericeus were collected in 44 sites (Hangang River 35 sites, Sapgyocheon Stream 4 sites, Daecheoncheon Stream 5 sites) among the noted 214 sampling stations investigated. Among these, the newly appearance streams were Ilricheon Stream, Samsancheon Stream, Bangyecheon Stream and Hanpocheon Stream in the Hangang River. In addition, the habitats and populations in the upper Seomgang River (Hoengseong Dam), lower Heukcheon Stream, Muhancheon Stream and Daecheoncheon Stream decreased due to dam construction, river work, water pollution, and the spread of the exotic species Micropterus salmoides. The main habitat of R. pseudosericeus was the middle-upper stream of clean water with slow water velocity, sand-pebble bottoms and lots of aquatic plants. Given this evidence as noted for the 30.2% reduction in occupancy within 10 years, due to the qualitative decline of habitat, the overfishing risk of ornamental fish and the spread of M. salmoides, in this case R. pseudosericeus is considered to be Vulnerable (VU A2cde) based on the IUCN Red List categories and criteria.

Comparative Research on Global Policy in ICT Accessibility for Vulnerable Groups -Focusing on Implementation of Legislative System- (취약계층을 위한 정보통신 접근성 정책에 대한 국가 간 비교 연구 -관련제도 중심으로-)

  • Kim, Jung-Yeon;Park, Sung-Woo;Kang, Byung-Gwon;Son, Chang-Yong;Jung, Bong-Keun
    • 재활복지
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    • v.20 no.1
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    • pp.131-150
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    • 2016
  • This study aims to compare global policies on ICT accessibility and to suggest possible solutions that help to enhance ICT accessibility for socially disadvantaged groups. The results indicated that related laws and standards in Korea are relatively well established than Asian countries' whereas they need improvements when compared to the US or the UK. Particularly, in spite of rapid development in information communication technology industry, incorporating the definition of newly developed technologies into existing laws related to ICT accessibility seemed slow that caused reluctancy of related parties to address accessibility issues the new technologies create. In addition, Korean government seems less effortful to develop policies and standards apart from web and mobile application accessibility. In order to resolve the problems, firstly, the period or process of enacting and amending laws can be shorten. Next, a government affiliated research institute can be established to do research and develop ICT accessibility related to user scenarios so that effective policies and standards could be readily provided. Even though other possible solutions can be suggested, what is more important than that is that any interested parties should sustainably make efforts to provide equal opportunities for the underserved populations.

Analysis of Genetic Characteristic of Jujube (Ziziphus jujuba Mill.) Cultivated in Korea Revealed by ISSR Markers (ISSR 표지를 이용한 국내 재배 대추나무의 유전특성 분석)

  • Nam, Jae-Ik;Lee, Uk;Kim, Sea-Hyun
    • Journal of Korean Society of Forest Science
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    • v.107 no.4
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    • pp.378-384
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    • 2018
  • Chinese jujube (Ziziphus jujuba Mill.), a member of family Rhamnaceae, is an economically important species. It has high nutritional value in fruits, and its medicinal properties have led to extensive use in traditional oriental medicine. In this study, we investigated the genetic characteristics of 270 jujube germplasms collected from the six major jujube fruit production areas in Korea including Boeun and Gyeongsan, in order to understand the current situation on cultivated varieties of domestic jujube and to obtain useful data for selection of superior germplasms and establishing their breeding plans. The results of ISSR marker analysis revealed that the Shannon's information index of the 270 germplasms was 0.107 and the genetic similarity was as high as 0.935 showing the dominance of a specific cultivar or germplasm, and almost 67% (180) of them were identified at the same genotype with 'Bokjo'. The domestic commercial jujube populations could be characterized by very low genetic diversity and thus may be vulnerable to external disturbances. In addition, it seems that most of the jujube fruits in domestic market were largely produced through parthenocarpy.

A Study on the Characteristics of Aquatic Insect Fauna in Differently Disrupted Ponds Located in Gungdaeoreum, Jeju (제주도 궁대오름 일대 교란정도가 다른 연못의 수서곤충 분포 특성에 관한 연구)

  • Ko, Gyeong Hun;Kim, Dong-Soon
    • Korean journal of applied entomology
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    • v.59 no.4
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    • pp.433-441
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    • 2020
  • This study was conducted to understand the distribution characteristics of aquatic insects in ecologically different ponds in terms of the disruption. We investigated the fauna of aquatic insects in three artificial ponds (pond 1, 2 and 3) and two natural ponds (pond 4 and 5) located within 1 km each other around Gungdaeoreum in Jeju Island, from March 2018 to June 2020. A total of 50 species belonging to 15 families were found in the surveyed ponds: total 850 individuals with 14 species in 4 families of the order Odonata, total 4,391 individuals with 14 species in 6 families of the order Hemiptera, and total 2,014 individuals with 22 species in 4 families of the order Coleoptera. In overall, total abundance and species numbers were relatively higher than those of artificial pond in natural ponds in which animal and plant ecosystems were well established. In the case of artificial ponds, the number of individuals and species recovered rapidly when reconstituted by introducing aquatic plants, etc. (Pond 1). The nymphs of Odonata were observed largely in ponds without natural enemies such as large fish, and where adults could freely access without interception by artificial structure. Phytophagous Corixidae of the order Hemiptera were abundant, and Haliplidae populations of the order Coleoptera were affected by the distribution of the plants. Accordingly, the major factors affecting aquatic insect abundance were identified as the presence of refuges such as the topography and aquatic plants and presence of predators. Species of the order, Odonata were vulnerable based on these factors. Our results can be useful as basic information for the restoration of wetlands and construction of artificial wetlands or for conservation of species diversity in the future.

Neurobiological Factors of Suicide (자살의 신경생물학적 요인)

  • Song, Hoo Rim;Woo, Young Sup;Jun, Tae Youn
    • Mood & Emotion
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    • v.10 no.1
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    • pp.13-21
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    • 2012
  • Suicide is a complex behavior associated with various neurobiological and psychosocial factors. It is considered that genetic polymorphism combined with environmental stress such as child-adolescent trauma make differences in neurobiological systems, which cause psychiatric disorders or pessimistic personality, impulse-aggressive behaviors, lack of judgment, and finally result in suicidal behavior. Much progress in the neurobiology of suicide has been made over the several decades. There seems to be a hereditary disposition to suicide independent of psychiatric disorder. The changes in neurotransmitters, neurohormones, neurotrophic factors, cytokines, lipid metabolisms related with their genetic polymorphism can contribute to disturbance of signal transductions and neuronal circuits vulnerable to suicide. It is likely that the main factors are dysfunctions of serotonin (5-HT) and hypothalamus-pituitary-adrenal (HPA) axis. Our understanding about the neurobiology of suicide is still limited. However, clinical practice could be assisted by neurobiological findings capable of making the detection of risk populations with higher sensitivity and the development of new treatment interventions. The settlement of biological markers in suicidal behaviors and their relationships is required.

Vegetation Structure and Site Characteristics of Rhododendron brachycarpum Population in South Korea (남한에서 만병초(Rhododendron brachycarpum D. Don ex G. Don) 개체군의 식생구조와 입지 특성)

  • Hwang, Yong;Han, Mu-Seok;Kim, Yong-Yul;Kim, Mu-Yeol
    • Korean Journal of Environment and Ecology
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    • v.28 no.6
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    • pp.751-761
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    • 2014
  • This study was carried out to analyze the vegetation properties, soil characteristics and ordination of Rhododendron brachycarpum population in South Korea. Rhododendron brachycarpum were mainly distributed along the Ulleungdo and Baekdudaegan of the Korean penninsula and it's population was located at an elevation of 872m to 1466m. The Rhododendron brachycarpum population was classified into Taxus cuspidata var. latifolia dominant population, Magnolia sieboldii dominant population, Thuja koraiensis dominant population and Rhododendron brachycarpum typical population. The composition of soil properties in the same areas are as follows: organic matter, total nitrogen, available phosphorous, exchangeable $K^+$, exchangeable $Ca^{2+}$, exchangeable $Mg^{2+}$ contained, and soil pH. The capacities of these chemical properties of the soil ranged from 10.45~15.28%, 0.37~0.61%, $0.21{\sim}0.35cmol^+/kg$, $0.39{\sim}2.54cmol^+/kg$, $0.17{\sim}0.50cmol^+/kg$, $18.28{\sim}22.81cmol^+/kg$ and 4.66~5.23 respectively. The results of the correlation between communities and soil conditions of vegetation of Rhododendron brachycarpum by DCCA ordination method are as follows: Taxus cuspidata var. latifolia dominant population was found in the very steep sloped area that has low percentage of total organic matter and nitrogen than other populations. Magnolia sieboldii dominant population and Thuja koraiensis dominant population was found in the steep sloped area that has high percentage of total organic matter and nitrogen than other populations. Thuja koraiensis dominant population was found in the gentle sloped area that has high percentage of altitudinal and rock exposure. Current status of Rhododendron brachycarpum is very vulnerable with a collection of herbs constantly threatening the species' survival. Thus, concrete conservation plans to protect natural habitats should be set up as soon as possible.

A Study on Vegetation Structure and Soil Condition of $Bletilla$ $striata$ Population (자란($Bletilla$ $striata$) 개체군의 식생구조와 토양특성)

  • So, Soon-Ku;Song, Ho-Kyung
    • Korean Journal of Environment and Ecology
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    • v.26 no.2
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    • pp.210-218
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    • 2012
  • This study was carried out to analyze the vegetation properties, soil characteristics and ordination of Bletilla striata population in South Korea. The $Bletilla$ $striata$ population was classified into $Juniperus$ $rigida$ dominant population, $Rhododendron$ $yedoense$ var. $poukhanense$ dominant population, $Rhus$ $javanica$ dominant population, $Bletilla$ $striata$ typical population. $Bletilla$ $striata$ were mainly distributed along the coast of south-western regions of the Korean penninsula and it's population was located at an elevation of 4m to 40m. In the study sites, soil organic matter, total nitrogen, available phosphate, exchangeable potassium, exchangeable calcium, exchangeable magnesium, cation exchange capacity and soil pH were 2.38-6.70%, 0.09-0.27%, 1.81-6.85mg/kg, 1.08-1.72$cmol^+/kg$, 3.56-7.71$cmol^+/kg$, 1.52-3.21$cmol^+/kg$, 5.28-16.95$cmol^+/kg$ and 4.60-6.01 respectively. $Rhododendron$ $yedoense$ var. $poukhanense$ dominant population was found in the steep sloped area that has high percentage of organic matter, total nitrogen, cation exchange capacity and pH than other populations. $Rhus$ $javanica$ dominant population was found in the gentle sloped area that has less percentage of organic matter, total nitrogen, cation exchange capacity and pH. $Juniperus$ $rigida$ dominant population and $Bletilla$ $striata$ typical population were found in the medium sloped area that has medium percentage of organic matter, total nitrogen, cation exchange capacity and pH. Current status of $Bletilla$ $striata$ habitats is very vulnerable with local development constantly threatening the species' survival. Thus, concrete conservation plans to protect natural habitats should be set up as soon as possible.

Christian Sabbath and Christian Education in the Era of 'Life Crisis' ('생명 위기'의 시대, 기독교의 안식, 그리고 기독교교육)

  • Ryu, Sam Jun
    • Journal of Christian Education in Korea
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    • v.67
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    • pp.339-375
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    • 2021
  • The author considers that contemporary society has entered the era of 'life on earth in peril' as a very serious situation in comparison with the past, and assumes that this life-in-peril situation, known as 'life crisis,' is one of the most urgent and important issues in Christian education as well as in public education. This urgency and importance is mainly based on the belief that Christianity is the religion of life that values all living beings' life and all Christians have the sacred vocation to cope with this crisis of life on earth, given by the life-giving God. For this reason, this study aims at identifying some tasks that Christian education should perform in the era of imperiled life, premising that diverse life-threatening situations and circumstances in today's world are closely related to the Christian Sabbath. More specifically, first of all, this article analyzes some notable phenomena of the life crisis in the contemporary world, such as deaths from intentional self-harm (suicides), deaths from industrial accidents and disasters, the real-life situation of vulnerable populations, people's indifference and insensitivity to the situation, and natural environmental degradation, by reflecting on current global issues as well as issues in Korea. This paper also criticizes neoliberalism, productivism, consumerism, economic materialism, egotism, and anthropocentrism as ideologies for causing these phenomena. After the criticism, the author interprets, from biblical and theological perspectives on the Christian Sabbath, main purposes and meanings of the Sabbath for contemporary society that are deeply connected with the crisis of life on earth: confessing that God takes the initiative to govern every creature's living and being; building the relationship with the God who has given the power of life to all living beings; practicing the Sabbath rest by living a holy life; and participating in the Sabbath rest as 'life-giving ministry.' In conclusion, this article suggests Christian educational practices that confront the life crisis, rooted in the purposes and meanings of the Christian Sabbath: reminding participants of the belief that God is the source of life on earth; cultivating 'life literacy'; helping people to resist the crisis of life; and encouraging humans to pursue the well-being and peace of both humanity and the earth.

Distribution Prediction of Korean Clawed Salamander (Onychodactylus koreanus) according to the Climate Change (기후변화에 따른 한국꼬리치레도롱뇽(Onychodactylus koreanus)의 분포 예측에 대한 연구)

  • Lee, Su-Yeon;Choi, Seo-yun;Bae, Yang-Seop;Suh, Jae-Hwa;Jang, Hoan-Jin;Do, Min-Seock
    • Korean Journal of Environment and Ecology
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    • v.35 no.5
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    • pp.480-489
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    • 2021
  • Climate change poses great threats to wildlife populations by decreasing their number and destroying their habitats, jeopardizing biodiversity conservation. Asiatic salamander (Hynobiidae) species are particularly vulnerable to climate change due to their small home range and limited dispersal ability. Thus, this study used one salamander species, the Korean clawed salamander (Onychodactylus koreanus), as a model species and examined their habitat characteristics and current distribution in South Korea to predict its spatial distribution under climate change. As a result, we found that altitude was the most important environmental factor for their spatial distribution and that they showed a dense distribution in high-altitude forest regions such as Gangwon and Gyeongsanbuk provinces. The spatial distribution range and habitat characteristics predicted in the species distribution models were sufficiently in accordance with previous studies on the species. By modeling their distribution changes under two different climate change scenarios, we predicted that the distribution range of the Korean clawed salamander population would decrease by 62.96% under the RCP4.5 scenario and by 98.52% under the RCP8.5 scenario, indicating a sharp reduction due to climate change. The model's AUC value was the highest in the present (0.837), followed by RCP4.5 (0.832) and RCP8.5 (0.807). Our study provides a basic reference for implementing conservation plans for amphibians under climate change. Additional research using various analysis techniques reflecting habitat characteristics and minute habitat factors for the whole life cycle of Korean-tailed salamanders help identify major environmental factors that affect species reduction.