• Title/Summary/Keyword: volume change ratio

Search Result 483, Processing Time 0.036 seconds

Treatment Response Evaluation by Computed Tomography Pulmonary Vasculature Analysis in Patients With Chronic Thromboembolic Pulmonary Hypertension

  • Yu-Sen Huang;Zheng-Wei Chen;Wen-Jeng Lee;Cho-Kai Wu;Ping-Hung Kuo;Hsao-Hsun Hsu;Shu-Yu Tang;Cheng-Hsuan Tsai;Mao-Yuan Su;Chi-Lun Ko;Juey-Jen Hwang;Yen-Hung Lin;Yeun-Chung Chang
    • Korean Journal of Radiology
    • /
    • 제24권4호
    • /
    • pp.349-361
    • /
    • 2023
  • Objective: To quantitatively assess the pulmonary vasculature using non-contrast computed tomography (CT) in patients with chronic thromboembolic pulmonary hypertension (CTEPH) pre- and post-treatment and correlate CT-based parameters with right heart catheterization (RHC) hemodynamic and clinical parameters. Materials and Methods: A total of 30 patients with CTEPH (mean age, 57.9 years; 53% female) who received multimodal treatment, including riociguat for ≥ 16 weeks with or without balloon pulmonary angioplasty and underwent both non-contrast CT for pulmonary vasculature analysis and RHC pre- and post-treatment were included. The radiographic analysis included subpleural perfusion parameters, including blood volume in small vessels with a cross-sectional area ≤ 5 mm2 (BV5) and total blood vessel volume (TBV) in the lungs. The RHC parameters included mean pulmonary artery pressure (mPAP), pulmonary vascular resistance (PVR), and cardiac index (CI). Clinical parameters included the World Health Organization (WHO) functional class and 6-minute walking distance (6MWD). Results: The number, area, and density of the subpleural small vessels increased after treatment by 35.7% (P < 0.001), 13.3% (P = 0.028), and 39.3% (P < 0.001), respectively. The blood volume shifted from larger to smaller vessels, as indicated by an 11.3% increase in the BV5/TBV ratio (P = 0.042). The BV5/TBV ratio was negatively correlated with PVR (r = -0.26; P = 0.035) and positively correlated with CI (r = 0.33; P = 0.009). The percent change across treatment in the BV5/TBV ratio correlated with the percent change in mPAP (r = -0.56; P = 0.001), PVR (r = -0.64; P < 0.001), and CI (r = 0.28; P = 0.049). Furthermore, the BV5/TBV ratio was inversely associated with the WHO functional classes I-IV (P = 0.004) and positively associated with 6MWD (P = 0.013). Conclusion: Non-contrast CT measures could quantitatively assess changes in the pulmonary vasculature in response to treatment and were correlated with hemodynamic and clinical parameters.

시멘트 경화체의 해수침식에 의한 성능저하 및 저항성 평가 (Evaluation on the Deterioration and Resistance of Cement Matric due to Seawater Attack)

  • 문한영;이승태;김홍삼
    • 콘크리트학회논문집
    • /
    • 제13권2호
    • /
    • pp.175-183
    • /
    • 2001
  • 국내에서 생산되는 5종류 시멘트로 제조한 시멘트 경화체의 해수침식에 대한 저항성을 알아보기 위한 목적으로 2배농도 인공 해수에 각각 400일 및 800일동안 침지시켜 모르타르의 압축강도 및 길이변화를 측정한 결과, 혼합시멘트계 모르타르가 광물질혼 화재의 영향으로 포틀랜드시멘트계 모르타르와 비교하여 좋은 결과를 나타내었다. 또한 시멘트 페이스트의 XRD분석에 의한 수 화 및 반응생성물의 피크강도비를 살펴보면, 포틀랜드시멘트계 페이스트 중 저열포틀랜드시멘트의 피크강도비가 가장 작았으며, 혼합시멘트계 페이스트의 경우 portlandite 및 brucite의 피크강도비가 포틀랜드시멘트계 페이스트보다 작았다. 인공해수 침식으 로 인한 시멘트 페이스트의 공극량을 수은압입법으로 측정한 결과에 의하면 보통포틀랜드시멘트 페이스트의 총공극량이 가장 크게 나타났으나, 포틀랜드시멘트에 고로슬래그미분말 및 플라이애시를 혼합한 혼합시멘트계 페이스트의 경우 총공극량이 각각 약 56% 및 약 32 % 정도 저감되는 효과가 있었다.

Preparation of Si/C Anode with PVA Nanocomposite for Lithium-ion Battery Using Electrospinning Method

  • Choi, Sung Il;Lee, Ye Min;Jeong, Hui Cheol;Jung, Eun-Jin;Lee, Mi Sun;Kim, Jinyoung;Kim, Yong Ha;Won, Yong Sun
    • Korean Chemical Engineering Research
    • /
    • 제56권1호
    • /
    • pp.139-142
    • /
    • 2018
  • Silicon (Si) is a promising anode material for next-generation lithium ion batteries (LIBs) because of its high capacity of 4,200 mAh/g ($Li_{4.4}Si$ phase). However, the large volume expansion of Si during lithiation leads to electrical failure of electrode and rapid capacity decrease. Generally, a binder is homogeneously mixed with active materials to maintain electrical contact, so that Si needs a particular binding system due to its large volume expansion. Polyvinyl alcohol (PVA) is known to form a hydrogen bond with partially hydrolyzed silicon oxide layer on Si nanoparticles. However, the decrease of its cohesiveness followed by the repeated volume change of Si still remains unsolved. To overcome this problem, we have introduced the electrospinning method to weave active materials in a stable nanofibrous PVA structure, where stresses from the large volume change of Si can be contained. We have confirmed that the capacity retention of Si-based LIBs using electrospun PVA matrix is higher compared to the conservative method (only dissolving in the slurry); the $25^{th}$ cycle capacity retention ratio based on the $2^{nd}$ cycle was 37% for the electrode with electrospun PVA matrix, compared to 27% and 8% for the electrodes with PVdF and PVA binders.

용적률 변화에 따른 공동주택 단지내 녹지구조 변화특성 (The Change of the Structure of Green Space by the Change of the Floor Area Ratio in Apartment Complex)

  • 김정호;이경재;김정호
    • 한국환경생태학회지
    • /
    • 제18권1호
    • /
    • pp.42-52
    • /
    • 2004
  • 본 연구는 공동주택단지 용적률변화에 따른 녹지면적 및 녹지구조의 변화파악을 목적으로 수행하였다. 대상지는 용적률 100%이하, 용적률 250%이하, 용적률 250%이상의 세 유형으로 구분하여 각 유형별로 2개소씩 선정하였다. 1970~1980년에 조성한 용적률 99%인 화곡제2주공아파트와 용적률 73%인 개포주공아파트는 녹지면적 비율 40.23~44.23%, 녹지 폭 3~ 15m 녹지 량 1.06~1.71㎥/$m^2$, 교목층 식재밀도 0.04~0.06주/$m^2$ 관목층 식재밀도 0.06 ~0.20주/$m^2$이었다. 1990년대에 조성한 용적률 226%인 등촌주공아파트와 용적률 240%인 개화 아파트는 녹지면적비율 24 16~26.16%, 녹지폭3~7m, 녹지량 0.84~l.54㎥/$m^2$, 교목층 식재밀도 0.18~0.31주/$m^2$, 관목층 식재밀도0.15~0.35주/$m^2$이었다. 1990년대말에 조성한 용적률 269%인 한보구암아파트와 용적률 376%인 동아3차아파트는 녹지면적비율 23.47~25.53%, 녹지폭 2~6m, 녹지량1.06~2.12㎥/$m^2$, 교목층 식재밀도 0.25주/$m^2$, 관목층 식재밀도 0.22~0.37주/$m^2$이었다. 용적률변화에 따른 녹지구조 분석결과 녹지면적은 용적률이 높을수록 넓었으나, 녹지량과 식재밀도는 용적률의 변화와 상관없이 전체적으로 낮은 상태이었고 식재구조는 외래종위주의 단층구조이었다.

순환골재를 이용한 환경 친화형 호안 블록제품의 개발에 관한 연구 (Study on the development of environment-friendly tetrapod using recycled aggregate)

  • 박도경;이명규;양극영
    • 한국건축시공학회지
    • /
    • 제6권2호
    • /
    • pp.73-79
    • /
    • 2006
  • The purpose of this study is to enhance the development of construction waste-recycling technologies and its economical efficiency by developing environment-friendly tetrapod, precast concrete, where recycled aggregate is used in order to promote recycling of waste concrete. The results of concrete mechanic characteristics experiments by the circulation coarse aggregate-replacement ratio are as the following. The circulation aggregate is lower and higher than natural aggregate in specific gravity and absorption ratio, respectively so that in case of mix proportioning, unit volume increases, while unit aggregate amount decreases. From the result, sufficient experiments of physical characteristics of circulation aggregate are required to get proper mix proportioning. When circulation aggregate-replacement ratio increases, compressive strength tends to decrease comprehensively, but 50% of replacement ratio is good enough to use. When circulation coarse aggregate's replacement ratio is 0%, drying shrinkage, which causes cracks in concrete and deteriorates durability, shows the minimum length change and the higher the ratio, the larger the length change. Thus. when using circulation coarse aggregate, drying shrinkage should be fairly examined. In freezing-and-thawing resistance, weight loss tends to comprehensively increase its loss at the circulation aggregate-mixed site. And the examination of surface aggregate-omission ratio is further needed and dynamic elastic modulus and durability factor(DF) require more study as well. In order to use circulation aggregate to tetrapod, a clear standard for strength should be first prepared and at the same time, more study about durability is needed.

준설매립토의 유실율 평가방법 정립에 관한 연구 (A Study on the Estimation Method of Loss Ratio in Dredged Fills)

  • 김석열;최효범;박재억;김승욱
    • 한국지반환경공학회 논문집
    • /
    • 제3권1호
    • /
    • pp.67-77
    • /
    • 2002
  • 준설토의 체적변화는 여수토를 통해 물과 함께 빠져나간 토립자의 유실량과 침강되어 새로이 형성된 지반 표면에서의 건조수축과 지반 내에서의 자중압밀에 의한 침하량의 합으로 생각할 수 있다. 그러나 현재까지 체적변화요인과 관련하여 자중압밀과 건조수축에 관한 연구에 비해 토립자의 유실과 관련된 연구는 미미한 실정이다. 따라서 본 연구에서는 준설토의 체적변화요인 중 여수토를 통해 외부로 유실되는 토량을 보다 명확히 규명하기 위해, 준설작업을 실시하기 전의 원지반과 준설토를 투기하여 조성된 매립 지역에서 각각 채취한 시료에 대한 입도분석결과에 Marsal의 수정파쇄율(일본토질공학회, 1990)을 적용하여 유실율을 평가하는 방법을 적용하였고, 이를 검증하기 위하여 기존의 방법을 이용하여 평가한 유실율과 비교 검토해 보았다. 또한 실내모형시험을 실시하여 현장계측 결과와 비교 검토하였으며 마지막으로 준설토를 단계투기법에 의하여 투기했을때 유실율에 미치는 영향을 실내모형시험을 통하여 확인하였다.

  • PDF

개량형 수평배수 압밀시험 장치에 의한 압밀특성 평가 (Assessment of Consolidation Properties Using Modified Oedometer for Radial Drainage Condition)

  • 전제성
    • 한국지반환경공학회 논문집
    • /
    • 제10권7호
    • /
    • pp.143-150
    • /
    • 2009
  • 연약지반의 적정 압밀속도 및 압밀침하량 예측에 있어 유효응력, 투수계수, 압밀계수, 체적변화계수 등의 물질함수는 가장 중요한 요소로 작용한다. 본 연구에서는 수평배수 조건에서의 압밀 물질함수 산정을 위한 개량형 수평배수 압밀시험 장치를 고안하고, 이를 이용하여 고함수비 해성점토에 대한 압밀시험을 실시하였다. 시험에 이용된 시료는 상부 준설매립 지반과 하부 원지반점토로 구성된 남해안 산업단지 조성 현장에서 채취하였다. 기존의 표준압밀시험을 동시에 실시하였으며, 이 결과를 이용하여 배수조건별 간극비, 유효응력, 투수계수, 압밀계수, 체적변화계수 등을 분석하였다. 압밀 물질함수는 Stark(2005)이 제안한 소성지수 포함의 회귀분석 방정식 형태로 표현되었으며, 이를 통해 투수성에 대한 이방성 특성을 산정할 수 있었다.

  • PDF

Preparation and Characterization of KOH-Activated Carbons Developed from Petroleum Coke

  • Sayed Ahmed, S.A.;Abo El-Enin, Reham M.M.;El-Nabarawy, Th.
    • Carbon letters
    • /
    • 제10권4호
    • /
    • pp.293-299
    • /
    • 2009
  • Potassium hydroxide activated carbons were prepared from Egyptian petroleum cokes with different KOH/coke ratios and at different activation temperatures and times. The textural properties were determined by adsorption of nitrogen at $-196^{\circ}C$. The adsorption of iodine and methylene blue was also investigated at $30^{\circ}C$. The surface area and the non-micropore volume increased whereas the micropore volume decreased with the increase of the ratio KOH/coke. Also the surface area and porosity increased with the rise of activation temperature from 500 to $800^{\circ}C$. Textural parameter considerably increased with the increase of activation time from 1 to 3 h. Further increasing of activation time from 3 to 4 h was associated with a less pronounced increase in textural parameters. The adsorption of iodine shows the same trend of surface area and porosity change exhibited by nitrogen adsorption, with KOH/coke ratio and temperature of activation. Adsorption of methylene blue follows pseudo-first-order kinetics and its equilibrium adsorption follows Langmuir and D-R models.

천마가 중대뇌동맥 폐쇄 흰쥐의 신경세포 자연사에 미치는 영향 (Effect of Gastrodiae Rhizoma on Apoptosis in Cerebral Infarction Induced by Middle Cerebral Artery Occlusion in Rats)

  • 윤유석;이종수
    • 한방재활의학과학회지
    • /
    • 제19권3호
    • /
    • pp.1-13
    • /
    • 2009
  • Objectives : This study evaluates neuroprotective effect of Gastrodiae Rhizoma on apoptosis in the cerebral infarct. Methods : Cerebral infarct was induced by the middle cerebral artery occlusion (MCAO) for 2 hours with intraluminal thread method in Sprague-Dawley rats. Then ethanol extract of Gastrodiae Rhizoma was administered orally for 3 days. Infarct area and volume were evaluated with TTC staining. Neuronal apoptosis was identified with TUNEL labeling. Apoptosis modulatory effect was observed with immunohistochemical Bax, Bcl-2, iNOS, and MMP-9 expressions in penumbra. Results : 1. Ethanol extract of Gastrodiae Rhizoma reduced infarct size partly and volume significantly of in the MCAO rat brain. 2. Ethanol extract of Gastrodiae Rhizoma reduced TUNEL positive cell ratio in the penumbra of MCAO rat brain significantly. 3. Ethanol extract of Gastrodiae Rhizoma suppressed Bax, iNOS and MMP-9 expression in the penumbra of MCAO rat brain significantly. 4. Ethanol extract of Gastrodiae Rhizoma did not change Bcl-2 expression in the penumbra of MCAO rat brain. But expression ratio of Bcl-2 against Bax was increased in the Gastrodiae Rhizoma group. Conclusions : These results suggest that Gastrodiae Rhizoma plays an anti-apoptotic neuroprotective effect through suppression of Bax, iNOS, and MMP-9 expressions and relative up-regulation of Bcl-2 in the ischemic brain tissue.

3차원 미세조직에 기반한 잔류응력 하의 이상 조직강의 소성변형률비 예측 (Prediction of the Plastic Strain Ratio Evolution of a Dual-phase Steel)

  • 하진진;이진우;이명규;;김지훈
    • 소성∙가공
    • /
    • 제24권6호
    • /
    • pp.395-399
    • /
    • 2015
  • A microstructure-based finite element simulation was conducted to predict the plastic strain ratio (R-value) of a dual-phase (DP) steel. The representative volume elements (RVEs) concept was adopted for the image-based FE modeling and a 3D model was constructed using sequential 2D images. Each phase was considered with the von-Mises yield criterion and the Swift model. The Swift parameters were defined by the empirical equations based on the chemical composition. The developed model was applied to analyze the effect of residual stress on the R-value and stress distribution. In order to consider the residual stress development after cold rolling, 10 % compression was applied in the thickness direction and unloaded before the tensile stress was applied in the rolling direction. The results showed a reasonable prediction for the R-value evolution: a sharp increase at small strains was well described and a transition followed in the downward direction. The R-value evolution was analyzed using the stress distribution change on the π-plane