• Title/Summary/Keyword: volume change ratio

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Treatment Response Evaluation by Computed Tomography Pulmonary Vasculature Analysis in Patients With Chronic Thromboembolic Pulmonary Hypertension

  • Yu-Sen Huang;Zheng-Wei Chen;Wen-Jeng Lee;Cho-Kai Wu;Ping-Hung Kuo;Hsao-Hsun Hsu;Shu-Yu Tang;Cheng-Hsuan Tsai;Mao-Yuan Su;Chi-Lun Ko;Juey-Jen Hwang;Yen-Hung Lin;Yeun-Chung Chang
    • Korean Journal of Radiology
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    • v.24 no.4
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    • pp.349-361
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    • 2023
  • Objective: To quantitatively assess the pulmonary vasculature using non-contrast computed tomography (CT) in patients with chronic thromboembolic pulmonary hypertension (CTEPH) pre- and post-treatment and correlate CT-based parameters with right heart catheterization (RHC) hemodynamic and clinical parameters. Materials and Methods: A total of 30 patients with CTEPH (mean age, 57.9 years; 53% female) who received multimodal treatment, including riociguat for ≥ 16 weeks with or without balloon pulmonary angioplasty and underwent both non-contrast CT for pulmonary vasculature analysis and RHC pre- and post-treatment were included. The radiographic analysis included subpleural perfusion parameters, including blood volume in small vessels with a cross-sectional area ≤ 5 mm2 (BV5) and total blood vessel volume (TBV) in the lungs. The RHC parameters included mean pulmonary artery pressure (mPAP), pulmonary vascular resistance (PVR), and cardiac index (CI). Clinical parameters included the World Health Organization (WHO) functional class and 6-minute walking distance (6MWD). Results: The number, area, and density of the subpleural small vessels increased after treatment by 35.7% (P < 0.001), 13.3% (P = 0.028), and 39.3% (P < 0.001), respectively. The blood volume shifted from larger to smaller vessels, as indicated by an 11.3% increase in the BV5/TBV ratio (P = 0.042). The BV5/TBV ratio was negatively correlated with PVR (r = -0.26; P = 0.035) and positively correlated with CI (r = 0.33; P = 0.009). The percent change across treatment in the BV5/TBV ratio correlated with the percent change in mPAP (r = -0.56; P = 0.001), PVR (r = -0.64; P < 0.001), and CI (r = 0.28; P = 0.049). Furthermore, the BV5/TBV ratio was inversely associated with the WHO functional classes I-IV (P = 0.004) and positively associated with 6MWD (P = 0.013). Conclusion: Non-contrast CT measures could quantitatively assess changes in the pulmonary vasculature in response to treatment and were correlated with hemodynamic and clinical parameters.

Evaluation on the Deterioration and Resistance of Cement Matric due to Seawater Attack (시멘트 경화체의 해수침식에 의한 성능저하 및 저항성 평가)

  • 문한영;이승태;김홍삼
    • Journal of the Korea Concrete Institute
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    • v.13 no.2
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    • pp.175-183
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    • 2001
  • Immersion tests with artificial seawater were carried out to investigate the resistance to seawater attack of 5 types of cement matrices. From the results of compressive strength and length change, it was found that blended cement mortars due to mineral admixtures, were superior to portland cement mortars with respect to the resistance to seawater attack. Moreover, XRD analysis indicated that the peak intensity ratio of low heat portland cement(LHC) paste, in portland cement pastes, had better results, and so did that of blended cement Paste. Pore volume of pastes by mercury intrusion porosimetry method demonstrated that total pore volume of ordinary portland cement(OPC) paste had a remarkable increase comparing with that of other pastes. In case of immersion of artificial seawater, the use of ground granulated blast-furnace slag and fly ash, however, showed the beneficial effects of 56% and 32% in reduction of total pore volume, respectively.

Preparation of Si/C Anode with PVA Nanocomposite for Lithium-ion Battery Using Electrospinning Method

  • Choi, Sung Il;Lee, Ye Min;Jeong, Hui Cheol;Jung, Eun-Jin;Lee, Mi Sun;Kim, Jinyoung;Kim, Yong Ha;Won, Yong Sun
    • Korean Chemical Engineering Research
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    • v.56 no.1
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    • pp.139-142
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    • 2018
  • Silicon (Si) is a promising anode material for next-generation lithium ion batteries (LIBs) because of its high capacity of 4,200 mAh/g ($Li_{4.4}Si$ phase). However, the large volume expansion of Si during lithiation leads to electrical failure of electrode and rapid capacity decrease. Generally, a binder is homogeneously mixed with active materials to maintain electrical contact, so that Si needs a particular binding system due to its large volume expansion. Polyvinyl alcohol (PVA) is known to form a hydrogen bond with partially hydrolyzed silicon oxide layer on Si nanoparticles. However, the decrease of its cohesiveness followed by the repeated volume change of Si still remains unsolved. To overcome this problem, we have introduced the electrospinning method to weave active materials in a stable nanofibrous PVA structure, where stresses from the large volume change of Si can be contained. We have confirmed that the capacity retention of Si-based LIBs using electrospun PVA matrix is higher compared to the conservative method (only dissolving in the slurry); the $25^{th}$ cycle capacity retention ratio based on the $2^{nd}$ cycle was 37% for the electrode with electrospun PVA matrix, compared to 27% and 8% for the electrodes with PVdF and PVA binders.

The Change of the Structure of Green Space by the Change of the Floor Area Ratio in Apartment Complex (용적률 변화에 따른 공동주택 단지내 녹지구조 변화특성)

  • 김정호;이경재;김정호
    • Korean Journal of Environment and Ecology
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    • v.18 no.1
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    • pp.42-52
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    • 2004
  • The purpose of this study was to propose the change of green area and green structure according to the change of the Floor Area Ratio(FAR) of apartment complex. The survey site was selected two each of apartment complex after due consider three type that is, the FAR below 100%, the FAR below 250% and the FAR over 250%. Green rate is 40.23~44.23%, green width is 3~15m, green volume is 1.06~1.71㎥/$m^2$, planting density of cannopy layer is 0.04~0.06tree/$m^2$, planting density of understory layer is 0.06~0.20tree/$m^2$ in case of Hwagok 2nd Jugong apartment(FAR 99%) and Gaepo Jugong apartment(FAR 73%) constructed in the 1970~1980. Green rate is 24.16~26.16%, green width is 3~7m, green volume is 0.84~1.54㎥/$m^2$, planting density of cannopy layer is 0.18~0.31tree/$m^2$, planting density of understory layer is 0.15~0.35tree/$m^2$ in case of Deungchon Jugong aparment(FAR 226%) and Gaehwa apartment(FAR240%) construsted in the mid-1990's. Green rate is 23.47~25.53%, green width is 2~6m, green volume is 1.06~2.12㎥/$m^2$, planting density of cannopy layer is 0.25tree/$m^2$, planting density of understory layer is 0.22~0.37tree/$m^2$ in case of Hanbo Guam apartment(FAR 269%) and Donga 3rd apartment(FAR 376%) constructed in the last-1990's. As the results of analysis of green structure according to changes of the Floor Area Ratio(FAR), the greater the FAR, the higher the rate of green area. The green volume and planted density is low without the change of the FAR and planted structure was simple-layer structure composed of alien woody species.

Study on the development of environment-friendly tetrapod using recycled aggregate (순환골재를 이용한 환경 친화형 호안 블록제품의 개발에 관한 연구)

  • Park Do-Kyong;Lee Myung-Kue;Yang Keek-Young
    • Journal of the Korea Institute of Building Construction
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    • v.6 no.2 s.20
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    • pp.73-79
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    • 2006
  • The purpose of this study is to enhance the development of construction waste-recycling technologies and its economical efficiency by developing environment-friendly tetrapod, precast concrete, where recycled aggregate is used in order to promote recycling of waste concrete. The results of concrete mechanic characteristics experiments by the circulation coarse aggregate-replacement ratio are as the following. The circulation aggregate is lower and higher than natural aggregate in specific gravity and absorption ratio, respectively so that in case of mix proportioning, unit volume increases, while unit aggregate amount decreases. From the result, sufficient experiments of physical characteristics of circulation aggregate are required to get proper mix proportioning. When circulation aggregate-replacement ratio increases, compressive strength tends to decrease comprehensively, but 50% of replacement ratio is good enough to use. When circulation coarse aggregate's replacement ratio is 0%, drying shrinkage, which causes cracks in concrete and deteriorates durability, shows the minimum length change and the higher the ratio, the larger the length change. Thus. when using circulation coarse aggregate, drying shrinkage should be fairly examined. In freezing-and-thawing resistance, weight loss tends to comprehensively increase its loss at the circulation aggregate-mixed site. And the examination of surface aggregate-omission ratio is further needed and dynamic elastic modulus and durability factor(DF) require more study as well. In order to use circulation aggregate to tetrapod, a clear standard for strength should be first prepared and at the same time, more study about durability is needed.

A Study on the Estimation Method of Loss Ratio in Dredged Fills (준설매립토의 유실율 평가방법 정립에 관한 연구)

  • Kim, Seog-Yeol;Choi, Hyo-Pum;Park, Jae-Eock;Kim, Seung-Wook
    • Journal of the Korean GEO-environmental Society
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    • v.3 no.1
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    • pp.67-77
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    • 2002
  • Volume change of the dredged soils is composed of the volume loss of soil particle flowing over an outflow weir with water and settlement due to both the self-weight consolidation in reclaimed layer and the desiccation at the surface of reclaimed layer. In order to estimate the amount of soil particles flowing over an outflow weir with water, the evaluation procedure of loss ratio of the dredged soils is proposed in the present study based on the Marsal's modified breakage theory and the results of hydrometer analyses. To verify a validity of the proposed procedure, evaluated loss ratio is compared with results from the other existing methods. The model test results and those of field test were compared and analyzed. Also, the variation of soil loss ratio was examined through the model test in the lab.

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Assessment of Consolidation Properties Using Modified Oedometer for Radial Drainage Condition (개량형 수평배수 압밀시험 장치에 의한 압밀특성 평가)

  • Jeon, Jesung
    • Journal of the Korean GEO-environmental Society
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    • v.10 no.7
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    • pp.143-150
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    • 2009
  • Material functions about effective stress, permeability, coefficient of consolidation and coefficient of volume change has important role to predict consolidation velocity and settlement of soft ground. Modified oedometer for radial drainage is adapted to find out material functions on laboratory tests. Undisturbed sample for laboratory tests were taken from construction sites of industrial complexes on southern coastal area which consists of upper dredged fill and lower original clay layer. For different drainage condition in consolidation process void ratio, effective stress, permeability, coefficient of consolidation and coefficient of volume change has been assessed with results of existing standard oedometer tests. It is worthwhile to note that consolidation material functions could be expressed as regression equation by Stark (2005), heterogeneity for permeability could be assessed from these relationships.

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Preparation and Characterization of KOH-Activated Carbons Developed from Petroleum Coke

  • Sayed Ahmed, S.A.;Abo El-Enin, Reham M.M.;El-Nabarawy, Th.
    • Carbon letters
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    • v.10 no.4
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    • pp.293-299
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    • 2009
  • Potassium hydroxide activated carbons were prepared from Egyptian petroleum cokes with different KOH/coke ratios and at different activation temperatures and times. The textural properties were determined by adsorption of nitrogen at $-196^{\circ}C$. The adsorption of iodine and methylene blue was also investigated at $30^{\circ}C$. The surface area and the non-micropore volume increased whereas the micropore volume decreased with the increase of the ratio KOH/coke. Also the surface area and porosity increased with the rise of activation temperature from 500 to $800^{\circ}C$. Textural parameter considerably increased with the increase of activation time from 1 to 3 h. Further increasing of activation time from 3 to 4 h was associated with a less pronounced increase in textural parameters. The adsorption of iodine shows the same trend of surface area and porosity change exhibited by nitrogen adsorption, with KOH/coke ratio and temperature of activation. Adsorption of methylene blue follows pseudo-first-order kinetics and its equilibrium adsorption follows Langmuir and D-R models.

Effect of Gastrodiae Rhizoma on Apoptosis in Cerebral Infarction Induced by Middle Cerebral Artery Occlusion in Rats (천마가 중대뇌동맥 폐쇄 흰쥐의 신경세포 자연사에 미치는 영향)

  • Youn, You-Suk;Lee, Jong-Soo
    • Journal of Korean Medicine Rehabilitation
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    • v.19 no.3
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    • pp.1-13
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    • 2009
  • Objectives : This study evaluates neuroprotective effect of Gastrodiae Rhizoma on apoptosis in the cerebral infarct. Methods : Cerebral infarct was induced by the middle cerebral artery occlusion (MCAO) for 2 hours with intraluminal thread method in Sprague-Dawley rats. Then ethanol extract of Gastrodiae Rhizoma was administered orally for 3 days. Infarct area and volume were evaluated with TTC staining. Neuronal apoptosis was identified with TUNEL labeling. Apoptosis modulatory effect was observed with immunohistochemical Bax, Bcl-2, iNOS, and MMP-9 expressions in penumbra. Results : 1. Ethanol extract of Gastrodiae Rhizoma reduced infarct size partly and volume significantly of in the MCAO rat brain. 2. Ethanol extract of Gastrodiae Rhizoma reduced TUNEL positive cell ratio in the penumbra of MCAO rat brain significantly. 3. Ethanol extract of Gastrodiae Rhizoma suppressed Bax, iNOS and MMP-9 expression in the penumbra of MCAO rat brain significantly. 4. Ethanol extract of Gastrodiae Rhizoma did not change Bcl-2 expression in the penumbra of MCAO rat brain. But expression ratio of Bcl-2 against Bax was increased in the Gastrodiae Rhizoma group. Conclusions : These results suggest that Gastrodiae Rhizoma plays an anti-apoptotic neuroprotective effect through suppression of Bax, iNOS, and MMP-9 expressions and relative up-regulation of Bcl-2 in the ischemic brain tissue.

Prediction of the Plastic Strain Ratio Evolution of a Dual-phase Steel (3차원 미세조직에 기반한 잔류응력 하의 이상 조직강의 소성변형률비 예측)

  • Ha, J.;Lee, J.W.;Lee, M. G.;Barlat, F.;Kim, J. H.
    • Transactions of Materials Processing
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    • v.24 no.6
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    • pp.395-399
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    • 2015
  • A microstructure-based finite element simulation was conducted to predict the plastic strain ratio (R-value) of a dual-phase (DP) steel. The representative volume elements (RVEs) concept was adopted for the image-based FE modeling and a 3D model was constructed using sequential 2D images. Each phase was considered with the von-Mises yield criterion and the Swift model. The Swift parameters were defined by the empirical equations based on the chemical composition. The developed model was applied to analyze the effect of residual stress on the R-value and stress distribution. In order to consider the residual stress development after cold rolling, 10 % compression was applied in the thickness direction and unloaded before the tensile stress was applied in the rolling direction. The results showed a reasonable prediction for the R-value evolution: a sharp increase at small strains was well described and a transition followed in the downward direction. The R-value evolution was analyzed using the stress distribution change on the π-plane