• Proceedings of the PSK Conference
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• 2003.04a
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• pp.252.2-252.2
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• 2003

It was difficult that we analysed the polymeric drugs for the physico-chemical properties. Sodium hyaluronate is a linear polysaccharide composed of repeating disaccharides of sodium glucuronate and N-acetyl glucosamine found throughout the tissues of the body with high concentrations in the vitreous humor. synovial fluid and umbilical cord. It has a role in regulating the interaction between adjoining tissues. (omitted)

• Journal of Veterinary Clinics
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• v.22 no.2
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• pp.163-165
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• 2005

An 18-month-old, female American Cocker Spaniel was presented with a cataract of left eye. The left eye was blind, and anterior uveitis was noted on ocular examination. Ultrasonography of the eye revealed a hyperechoic mass with distinct borders in the vitreous indicative of lens fiber or mass lesion extending from ciliary body. The eye was enucleated after ultrasonographic examination. On gross examination, rupture of posterior capsule was noted adjacent to the ciliary body.

• The Korean Journal of Soil Zoology
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• v.5 no.2
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• pp.101-112
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• 2000

Spiders usually have poor vision but not the jumping spiders. Their eight eyes are located on its distinctive box-shaped head and relatively well developed. The Spiders were fixated with 3% glutaraldehyde and thin section was performed with ultra-microtome. The specimens were observed with light microscopy, transmission and scanning electron microscopy. Eye area of jumping spider is competed of three rows. The first eye row comprise four eyes. Among them, two anterior median eyes are the largest and two anterior lateral eyes are relatively small. The former are main-eyes and have excellent vision. The second row, which has the two smallest eyes, is located about midway between the first and third rows. The third row is about half-way back on the thorax and eyed of which are middle size. To investigate ultrastructure of salticid spiders'eye, Menemerus fulvus was chosen. All of Menemerus fuvus's eyes are composed of cornea, lens, vitreous body and retina in histologically. Cornea layer, linked to exocuticle of exoskeleton. is regular layer structure without any cell tripe. Lenses are biconvex type. Retinas comprise well developed microvilli-shape rhabdomeres, unpigmented supporting cells, and pigmented cell. Retinas of anterior median eyes are surrounded by circular cylinder-shaped vitreous body, photoreceptor, i.e. rhabdomeres, of it is irregularly arranged compared to the other eyes.

• Journal of the Korean Society of Radiology
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• v.18 no.3
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• pp.283-292
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• 2024

Radiation side effects and complications on the ocular adnexa during electron beam therapy for orbital lymphoma can increase the incidence of posterior subcapsular cataracts. This study simulated a medical linear accelerator and a mathematical model of the eye using monte carlo simulations to evaluate the dose to the ocular adnexa and compare the shielding effectiveness on different parts of the ocular adnexa based on lens shield thickness. The dose assessment results of the ocular adnexa showed that the lens's sensitive area had the highest absorbed dose distribution when no shield was used, followed by the lens's non-sensitive area, the anterior chamber, vitreous humor, cornea, and eyelid in descending order. With the use of a shield, a 2 mm thick shield demonstrated a dose reduction effect of over 90% in the lens's sensitive area, over 83% in the non-sensitive area and anterior chamber, and a dose reduction effect of 30 to 62% in the vitreous body, cornea, and eyelid. For dose reduction in the lens's sensitive area during electron beam therapy for orbital lymphoma, it is necessary to use a shield of at least 2 mm thickness. Additionally, shielding strategies considering the thickness and area of the shield for other ocular adnexa besides the lens are required.

• Applied Microscopy
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• v.30 no.1
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• pp.1-9
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• 2000

The wandering spider, Pardosa astrigera, had four pairs of ocelli that arranged in three rows on the cephalothorax. Along the anterior margin lay a pair of small anterior median (AM) eye flanked on each side by anterior lateral (AL) eye. Two large posterior median (PM) eye was situated on the clypeus behind the anterior row and still more posteriorly was a pair of posterior lateral (PL) eye. The visual cell of retina consisted of cell body, rhabdome, and intermediate segment. Bipolar neuron was found in anterior median eye (principal eye) and unipolar neuron in others (secondary eye). Rhabdome showed that arranged in PMeye and PLeye. But rhabdomes of AMeye and ALeye were irregular in retina. Except AMeye, incontinuous tapetum found in ALeye, PMeye, PLeye. Anterior median eye was similar to anterior lateral eye in length and posterior median eye similar to posterior lateral eye. Component size of eye were similar to 4 pairs eye in cornea. Size of lens, cell body, and rhabdome was similar not only anterior median eye and anterior lateral eye but also posterior median eye and posterior lateral eye. Vitreous body was large posterior median eye than others.

• Journal of Korean Ophthalmic Optics Society
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• v.9 no.1
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• pp.135-143
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• 2004

The Human body is subject to two patterns of senescence, both of which are represented in the eye and vision. This article discusses the anatomical and physiological changes in anterior and posterior segments which occur with age. The areas covered include the globe, lids, tears, conjunctiva, cornea, sclera, anterior chamber angle, iris, lens, choroid, vitreous and retina. A sample of 219 individuals between the ages of 50 and 79 years was tested with case history, slit lamp examination, palpebral fissure, horizontal visible iris diameter(HVID) and pupil size. The palpebral fissure decreases with age while HVID remains constant in all age classes. This study suggests that an understanding of anatomical and physiological changes which occur with age is helpful to all eye clinicians because the aging process affects all of the ocular tissues.

• Journal of Korean Ophthalmic Optics Society
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• v.16 no.1
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• pp.91-95
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• 2011

Purpose: In this study, we investigated the dye to staining for selective accumulation in rabbit retina. Methods: Rhodamine B was injected into the vitreous body in rabbit. After 24 h, the isolated retina was checked condition of cell staining on the microscope. We used conventional immunocytochemical techniques for recognizing cell type. Results: Well-labeled nuclei were seen in the middle of the inner nuclear layer of the rabbit retina. The number and distrbution of the accumulating cells were similar to those of the m$\ddot{u}$ller glia. To identify m$\ddot{u}$ller cell, we used antibody directed against vimentin. Rhodamine B-immunoreactive nuclei also were labeled with antivimentin antibody. We found that Rhodamine B was accumulated selectively in retinal m$\ddot{u}$ller cell. Conclusions: Specific accumulation in rabbit retinal m$\ddot{u}$ller cell occurred when Rhodamine B was applied to living retina.

• Parasites, Hosts and Diseases
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• v.51 no.2
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• pp.223-229
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• 2013

This study aimed to explore the clinical, radiological, and pathological characteristics of intraocular cysticercosis due to Taenia solium metacestode infection. Total 8 patients diagnosed with intraocular cysticercosis at the Red Cross Hospital of Yunnan Province, China were examined retrospectively. Patients with clear dioptic media had undergone fundus chromophotography. All patients underwent B ultrasonography of the ocular region (CT) successive scanning of the orbit and cerebral tissues. Parasites were extracted surgically and then examined pathologically. The fundus chromophotography showed a white and condensing scolex package in the vesicle. The B ultrasonic examination showed a vesicle-like echogenic mass in the vitreous chamber, in which the high-level echo spot was the cysticercus scolex. The pathological examinations showed that the vesicle wall exhibited hyaline degeneration, inflammatory cell infiltration, neuroglial fiber, and glial cell proliferation layers from the inside to the outside. The scolex is round and is composed of the outer tissue (the body wall) and the inner furrow tissue; these tissues migrated together. Primordially differentiated sucking discs were found in one case, but no hooklets were found. The inner scolex tissue was folded like a paper flower. The severity of intraocular disease is closely correlated with the pathophysiological processes of the cysticercus worm. Pathological examination of the intraocular lesions can help to evaluate the course of the disease as well as to provide a scientific basis for effective antiparasitic medication.

• Toxicological Research
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• v.22 no.4
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• pp.411-416
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• 2006

This study was carried out to investigate the spaciotemporal plasticity of intergeniculate leaflet in postnatal mongolian gerbil using genetically modified pseudorabies virus recombinant, which was a kind of excellent neurotracer with the ability to transpass the neuronal synaptic cleft. In addition, we tried to evaluate the special role of intergeniculate leaflet as a signal controler of circardian rhythm by expression of various nourotransmitters in suprachiasrnatic nucleus. The PRV-BaBlu, a genetically modified strain of PRV-Bartha with lac-Z gene, was injected into vitreous body of postnatal mongolian gerbil, and immunostained. The PRV-Bablu infected the neurons in intergeniculate leaflet of postnatal mongolian gerbil, and the degree of viral infection in postnatal period of experimental animals had tendency to increase with time consuming. This results showed that the mutant PRV-Bar-tha strain with lac-Z gene, PRV-BaBlu, was a very excellent neurotracer to localize the retinogeniculate tract with infection of neurons in intergeniculate leaflet specially.

• Journal of Life Science
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• v.24 no.5
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• pp.498-504
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• 2014

Mammalian hyaluronidases (HAase, EC 3.2.1.35) are a family of enzymes that hydrolyse N-acetyl-D-glucosamine (1-4) glycosidic bonds in hyaluronic acid, which is found in skin, cartilage, and the vitreous body. Although HAase is generally present in an inactive form within subcellular lysosomes, it is released in an active form in some types of inflammation and tissue injuries, thereby contributing to the inflammatory response. The HAase inhibitory activity of 500 methanolic extracts of 500 species from medicinal plants was screened using a Morgan microplate assay. The viscosity of the hyaluronic acid was measured with an Ubbelohde viscometer. Three MeOH extracts inhibited more than 50% of HAase activity at a concentration of 2 mg/ml. HAase inhibitory rates (%) of three species of medicinal plant extracts, Styrax japonica, Deutzia coreana, and Osmanthus insularis were 57.28%, 53.50%, and 53.19%, respectively. The rate of HAase inhibition of the extracts was dose dependent. In the HAase inhibitory assay using the Ubbelohde viscometer, the results were in good agreement with the results from the Morgan assay. The results suggest that HAase inhibitory compounds extracted from the stem of S. japonica, D. coreana, and O. insularis might be multifunctional and prevent the degradation of hyaluronic acid and the induction of allergic reactions and inflammation.