• Title/Summary/Keyword: vitexin

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Norisoprenoids and Hepatoprotective Flavone Glycosides from the Aerial Parts of Beta vulgaris var. cicla

  • Kim, In-Kyum;Chin, Young-Won;Lim, Song-Won;Kim, Young-Choong;Kim, Jin-Woong
    • Archives of Pharmacal Research
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    • v.27 no.6
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    • pp.600-603
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    • 2004
  • (+)-Dehydrovomifoliol (1). 3-hydroxy-5$\alpha$,6$\alpha$-epoxy-$\beta$-ionone (2), vitexin 7 -O-$\beta$-D-glucopyrano-side (3), and vitexin 2'-O-$\beta$-D-glucopyranoside (4) were isolated as new constituents from the aerial parts of Beta vulgaris var. cicla. Compounds 3 and 4 demonstrated hepatoprotective activity with values of 65.8 and 56.1%, respectively, in primary cultured rat hepatocytes with $CCl_4$-induced cell toxicity, compared to controls. This was comparable to that of silibinin (69.8%) which was used as a positive control.trol.

Antioxidative and anti-inflammatory activities of Phaseolus aureus

  • Hong, In-Taik;Kim, Beom-Jun;Yu, Duck-Cho;Kim, Jung-Haeng;Kim, Jung-Han;Heo, Moon-Young;Lee, Song-Jin;Kim, Hyun-Pyo
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.22 no.2
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    • pp.41-51
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    • 1996
  • Phaseolus aureus (mung bean), Leguminosae, has been used as an antidote from the ancient time. Especially, it has been widely used for cleaning face and skin in oriental countries. Although several constituents such as fatty acids, phytoallexin and phaseol derivatives were reported in P. aureus and related species including seedlings, there has been a few report to describe its biological activity. Therefore, in this investigation, the ethanol extract from P. aureus was obtained and its biological activities including the antioxidative and anti-inflammatory activities were studied. The 70% ethanol extract from P. aureus showed dose-dependent antioxidative activity (52.3% inhibition at 4 mg/ml) against lipid peroxidation assay, while the extract did not show the inhibitory activity of superoxide radical formation. The extract also showed the topical anti-inflammatory activity against croton-oil and arachidonic acid induced mouse ear edema test (18-19% inhibition at 7.5 mg/ear) as well as mild inhibitory activity against picryl chloride induced delayed hypersensitivity in mouse. For investigating active principles, vitexin and isovitexin (apigenin C-glycoside) as flavonoids, and adenosine were isolated from the extract using silica gel chromatography. The actual contents of vitexin and isovitexin were found to be 3.7 and 2.4 mg/g extract, respectively. Vitexin and isovitexin showed the antioxidative activity. They showed the topical anti-inflammatory activity, although the activities were not potent compared to the reference compounds. These results suggested that vitexin and isovitexin may be, at least in part, the compounds contributing the antioxidative activity in vitro and the topical anti-inflammatory activity of P. aureus in vivo. All results of present study might be one of the scientific rationale in using mung bean for skin care from the ancient time.

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Pharmaco-Constituents of Crataegus Pinnatifida var. Pubescens Leaves (털산사나무잎의 약효성분)

  • 김정수;김일혁
    • YAKHAK HOEJI
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    • v.37 no.2
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    • pp.193-197
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    • 1993
  • For the investigation of medicinal resources in Crataegus species, a study was carried out to clarify the constituents in the leaves of Crataegus Pinnatifida var. pubescens (Rosaceae), of which fruits have been used to stomachic, digestive, astringent, analgesic, and cardiotonic, etc. as a folk medicine in Korea. From the n-BuOH fraction of MeOH extract two flavone glycosides, vitexin(apigenin-8-C-$\beta$-D-glucopyranoside) and 2"-O-rhamnosyl vitexin(apigenin-8-C-$\alpha$-L-rhamnosyl-(1$\rightarrow$2)-$\beta$-D-glucopyrano side) were isolated and identified on the basis of their physico-chemical properties and spectroscopic evidences(UV, IR, NMR, FAB-Mass etc.) in comparision with authentic samples.amples.

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Effect of Seeding Times on Yield and Flavonoid Contents of Mungbean (녹두 파종기에 따른 수량과 Flavonoid 함량 변화)

  • Kim, Dong-Kwan;Chon, Sang-Uk;Lee, Kyung-Dong;Kim, Kyong-Ho;Rim, Yo-Sup;Jeong, Seok-Cheol
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.53 no.3
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    • pp.273-278
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    • 2008
  • This study set out to investigate the changes to the growth, yield, and flavonoid contents of mungbean according to different seeding times from mid May to mid July in the southern region of Korea. Days to first flowering, days to first maturing, and cultivation period were shorter at later seeding time than earlier seeding time. But later the seeding time was, days from first maturing to first harvesting, days required between harvesting increased. Number of pods at first harvesting and yield of mungbean were highest when seeded at late June, showing increase in yield 14% more than at early June as standard seeding time. However number of seeds per pod and 1,000-seed weight at first harvesting were highest when seeded at mid July. The number of harvesting was smallest at two times when seeded at June or mid July. The contents of average vitexin and isovitexin in mungbean were highest in the order of mid July, late June, and mid May. In particular, their contents reached its highest point in the seeds of the second harvest. Considering the results of the cultivation period, yield, harvesting times, vitexin and isovitexin contents, the proper seeding time of mungbeans in the southern region of Korea will be from late June to mid July.

Chemical Constituents of Kyllinga brevifolia (수오공의 화학성분)

  • Shin, Dong-In;Kim, Jin-Woong
    • YAKHAK HOEJI
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    • v.38 no.6
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    • pp.770-774
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    • 1994
  • The chemical constituents of Kyllinga brevifolia Rottb. var. leiolepsis Hara (Cyperaceae) were studied. From the chloroform and n-butanol soluble fractions, five compounds were isolated by chromatographic purification process. They were identified as ${\beta}-sitostenone$, ergosterol peroxide, ${\beta}-sitosterol$, ${\beta}-sitosteryl$-3-O-{\beta}-D-glucopyanoside and vitexin, respectively. This is the first report of the identification of ${\beta}-sitostenone$, ergosterol peroxide from Cyperaceae.

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Studies on the Components of the Seeds of Phaseolus radiatus (녹두의 성분연구)

  • Shin, Soon-Hee;Kang, Sam-Sik;Kwon, Kyung-Sook
    • YAKHAK HOEJI
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    • v.34 no.4
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    • pp.282-286
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    • 1990
  • An hydrocarbon alcohol and steroids were isolated from the hexane fraction of the extract from the seeds of Phaseolus radiatus L. And also a flavonoid was identified from the ethyl acetate and butanol fraction. The structure of the obtained compound were elucidated by spectroscopic methods (UV, IR, mass and NMR) and their physicochemical properties. As the results, triacontanol, stigmasterol, ${\beta}-sitosterol$ and vitexin were identified.

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Quality characteristics and preparation of Dasik using roasted mung bean (로스팅 녹두를 이용한 다식 제조 및 품질특성)

  • Jang, Si Sung;Kim, Min Jeong;Kim, Ae Jung
    • Korean Journal of Human Ecology
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    • v.23 no.2
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    • pp.357-366
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    • 2014
  • In this study, we manufactured mung bean Dasik (pattern pressed candy) after selecting the optimum roasting conditions through physiochemical analysis and sensory evaluation. Then anti-oxidative abilities of roasted mung bean were measured in order to develop beauty food (Dasik) using roasted mung bean. In the content of vitexin and isovitexin of roasted mung bean, about 10 times the vitexin in the seed(60.85 mg/g) is found in the skin of raw mung bean, and about 9 times the isovitexin in the seed(71.42 mg/g) is also found in the peel. As a result of analyzing the seed and peel of mung bean after roasting it for 10, 20 and 30 minutes respectively, the optimum roasting condition is thought to be $110^{\circ}C$ for 30 minutes as the contents of vitexin and isovitexin showed the highest values of 104.94 mg/g and 122.02 mg/g respectively when the mung bean was roasted at $110^{\circ}C$ for 30 minutes. In the anti-oxidative activity evaluation of the optimum mung bean Dasik, the total content of phenol was shown to be 0.15 mg/mL, and the total content of flavonoid was shown to be 0.026 mg/mL. The DPPH radical scavenging ability showed a high vitality of 58.19%, and the ABTS radical scavenging ability was shown to be 13.26%.

Studies on the flavonoids of the Hibiscus syriacus L. Complex (무궁화 품종내의 flavonoid 성분분포에 관한연구)

  • 유기역
    • Korean Journal of Plant Resources
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    • v.9 no.3
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    • pp.224-229
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    • 1996
  • Floral flavonoids of Hibiscus syriacus L. six complex with 68 formac all in all were examined. Thirteen flavonoids appeared on the two dimensional chromatogtams. Spot 5, however, occupied more than 50% in total flavonoid contents, and other spots were invariably minor pigments in all samples examined. Ten spots among 13 spots showed the characteristics of flavones, having color of purple to dark purple under UV light and yellow under ammonia gas, while spots reagents suggests that 10 purple spots are 4', 5-OH aglycone type. Four spots out of 10 purple spots were possible to be identified: spot 5, saponarin, spot 7, vitexin, spot 9, xylovitexin, and spot 11, rhamnosylvitexin, respectively. It was suggested that spot 13 might be apigenin-7-O-diglycoside.

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Effect of Mulching and Soil Conditioners on Yield and Flavonoids Content of Mungbean (녹두 수량과 Flavonoids 함량에 대한 멀칭과 토양개량제 효과)

  • Kim, Dong-Kwan;Chon, Sang-Uk;Lee, Kyung-Dong;Son, Dong-Mo;Rim, Yo-Sup;Kim, Kyong-Ho
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.53 no.4
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    • pp.353-358
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    • 2008
  • The purpose of this study was to examine the effects of black polyethylene film mulching and soil conditioners on the growth, yield, and flavonoids biosynthesis of mungbeans. The seedling stand rate, plant height, and pods per plant were 98%, 61 cm, and 15.1, respectively, when the mungbean grown black polyethylene film mulches. They were greater than these results when the without mulches was applied by 13%, 9 cm, and 1.8, respectively. Mungbean grown with black polyethylene film mulches ($243\;kg{\cdot}10a^{-1}$) exhibited 38% more seed yield than without mulches ($176\;kg{\cdot}10a^{-1}$). However, no significant difference in contents of vitexin and isovitexin of mungbeans between with black polyethylene film mulches and without mulches was observed. Among soil conditioners, standard fertilizer+oil cake and standard fertilizer+mineral powders increased number of pods. The standard fertilizer+oil cake showed the highest seed yield (119%) of mungbean when it mixed with standard fertilizers, and followed by mineral powders (115%). The mixed combinations of oil cake or mineral powders also seem to have affected the biosynthesis of vitexin and isovitexin, whose content in mungbeans was significantly more.