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Norisoprenoids and Hepatoprotective Flavone Glycosides from the Aerial Parts of Beta vulgaris var. cicla  

Kim, In-Kyum (College of Pharmacy and Research Institute of Pharmaceutical Science, Seoul National University)
Chin, Young-Won (College of Pharmacy and Research Institute of Pharmaceutical Science, Seoul National University)
Lim, Song-Won (College of Pharmacy and Research Institute of Pharmaceutical Science, Seoul National University)
Kim, Young-Choong (College of Pharmacy and Research Institute of Pharmaceutical Science, Seoul National University)
Kim, Jin-Woong (College of Pharmacy and Research Institute of Pharmaceutical Science, Seoul National University)
Publication Information
Archives of Pharmacal Research / v.27, no.6, 2004 , pp. 600-603 More about this Journal
Abstract
(＋）-Dehydrovomifoliol (1）. 3-hydroxy-5$\alpha$,6$\alpha$-epoxy-$\beta$-ionone (2）, vitexin 7 -O-$\beta$-D-glucopyrano-side (3）, and vitexin 2'-O-$\beta$-D-glucopyranoside (4） were isolated as new constituents from the aerial parts of Beta vulgaris var. cicla. Compounds 3 and 4 demonstrated hepatoprotective activity with values of 65.8 and 56.1％, respectively, in primary cultured rat hepatocytes with $CCl_4$-induced cell toxicity, compared to controls. This was comparable to that of silibinin (69.8％） which was used as a positive control.trol.
Keywords
Beta vulgaris var. cicla; Hepatoprotective activity; Flavonoid; (＋)-Dehydrovomifo-liol; $3-Hydroxy-5{\alpha}$,$6{\alpha}-epoxy-{\beta}-ionone$; $Vitexin{\; }7-O-{\beta}-D-glucopyranoside$; $Vitexin{\; }2"-O-{\beta}-D-glu-copyranoside$;
Citations & Related Records

Times Cited By Web Of Science : 7  (Related Records In Web of Science)
Times Cited By SCOPUS : 6
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