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Study on the Improvement of Adhesion between Cu Laminate and PSR (동박과 PSR간의 접합력 향상에 관한 연구)

  • 김경섭;정승부;신영의
    • Journal of Welding and Joining
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    • v.17 no.2
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    • pp.61-65
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    • 1999
  • Because of the need for packages which accommodate high pin count, high density and high speed device, PBGA(plastic ball grid array) package gets more spotlight. But the substrate material which is used for PBGA package is in nature susceptible to moisture penetration. The objective of the study is to find out the path of delamination in the stacked structure of substrate. To increase the adhesion between the cooper laminate and PSR(photo solder resist) which is the weakest part, experiments were performed by changing parameters of printing pre-treatment and post-treatment process. As a result of experiments, the factor effects on the adhesion between the cooper laminate and PSR is caused by all of the pre-treatment and post-treatment condition. A considerable change was observed depending on the amount of UV irradiation after thermal cure which is typical of printing post-treatment condition rather than pre-treatment condition.

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Deciphering the molecular mechanisms of epitranscriptome regulation in cancer

  • Han, Seung Hun;Choe, Junho
    • BMB Reports
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    • v.54 no.2
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    • pp.89-97
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    • 2021
  • Post-transcriptional regulation is an indispensable cellular mechanism of gene expression control that dictates various cellular functions and cell fate decisions. Recently, various chemical RNA modifications, termed the "epitranscriptome," have been proposed to play crucial roles in the regulation of post-transcriptional gene expression. To date, more than 170 RNA modifications have been identified in almost all types of RNA. As with DNA modification-mediated control of gene expression, regulation of gene expression via RNA modification is also accomplished by three groups of proteins: writers, readers, and erasers. Several emerging studies have revealed that dysregulation in RNA modification is closely associated with tumorigenesis. Notably, the molecular outcomes of specific RNA modifications often have opposite cellular consequences. In this review, we highlight the current progress in the elucidation of the mechanisms of cancer development due to chemical modifications of various RNA species.

Prediction of the load-displacement response of ground anchors via the load-transfer method

  • Chalmovsky, Juraj;Mica, Lumir
    • Geomechanics and Engineering
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    • v.20 no.4
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    • pp.359-370
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    • 2020
  • Prestressed ground anchors are important structural elements in geotechnical engineering. Despite their widespread usage, the design process is often significantly simplified. One of the major drawbacks of commonly used design methods is the assumption that skin friction is mobilized uniformly along an anchor's fixed length, one consequence of which is that a progressive failure phenomenon is neglected. The following paper introduces an alternative design approach - a computer algorithm employing the load-transfer method. The method is modified for the analysis of anchors and combined with a procedure for the derivation of load-transfer functions based on commonly available laboratory tests. The load-transfer function is divided into a pre-failure (hardening) and a post-failure (softening) segment. In this way, an aspect of non-linear stress-strain soil behavior is incorporated into the algorithm. The influence of post-grouting in terms of radial stress update, diameter enlargement, and grout consolidation is included. The axial stiffness of the anchor body is not held constant. Instead, it gradually decreases as a direct consequence of tensile cracks spreading in the grout material. An analysis of the program's operation is performed via a series of parametric studies in which the influence of governing parameters is investigated. Finally, two case studies concerning three investigation anchor load tests are presented.

Post-Processing for JPEG-Coded Image Deblocking via Sparse Representation and Adaptive Residual Threshold

  • Wang, Liping;Zhou, Xiao;Wang, Chengyou;Jiang, Baochen
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.11 no.3
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    • pp.1700-1721
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    • 2017
  • The problem of blocking artifacts is very common in block-based image and video compression, especially at very low bit rates. In this paper, we propose a post-processing method for JPEG-coded image deblocking via sparse representation and adaptive residual threshold. This method includes three steps. First, we obtain the dictionary by online dictionary learning and the compressed images. The dictionary is then modified by the histogram of oriented gradient (HOG) feature descriptor and K-means cluster. Second, an adaptive residual threshold for orthogonal matching pursuit (OMP) is proposed and used for sparse coding by combining blind image blocking assessment. At last, to take advantage of human visual system (HVS), the edge regions of the obtained deblocked image can be further modified by the edge regions of the compressed image. The experimental results show that our proposed method can keep the image more texture and edge information while reducing the image blocking artifacts.

Implementation of an ASP Upload Component to Comply with RFC 1867 (RFC 1867 규격을 준수하는 ASP 업로드 컴포넌트 설계)

  • Hwang Hyun-Ju;Kang Koo-Hong
    • The Journal of the Korea Contents Association
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    • v.6 no.3
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    • pp.63-74
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    • 2006
  • Recently many ASP applications have been released which enable them to accept, save and manipulate files uploaded with a web browser. The files are uploaded via an HTML POST form using RFC 1867 In particular, the file transfer via the HTTP port is getting more important because of the current Internet security issues. In this paper, we implement a form-based ASP upload component and disclose explicitly most of the main codes. That is, the open source might be helpful to develop the new ASP applications including file upload function in the future. We also show the upload time and CPU usage time of the proposed upload component and compare with the well-known commercial ones, showing the performance metrics of the proposed component are comparable to those of commercial ones.

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Enhancement of Airfoil Post-Stall Characteristics via a Jet Blowing (제트 블로잉에 의한 에어포일의 실속후 특성 향상)

  • Lee, Ki-Young;Chung, Heong-Seok;Cho, Dong-Hyun;Sohn, Myong-Hwan
    • Journal of the Korea Institute of Military Science and Technology
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    • v.10 no.2
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    • pp.188-197
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    • 2007
  • Active flow control, in the form of steady and unsteady momentum injection via jet blowing was studied. A jet was obtained by pressing a plenum inside the airfoil and ejecting flow out of a thin slot. The normal and drag forces were measured with leading edge or trailing edge blowing Jet and compared with the results obtained with no blowing. The blowing jet has been shown to improve the aerodynamic performance of the airfoil. The steady jet proved more effective than pulsating jet in these experimental conditions. Furthermore for the case of leading edge steady blowing jet, the alleviation of non-linearity in the normal force curve slope can be seen at higher angles of attack. No effective trailing edge jet was observed in this highly separated flow. This shows that the stall control is highly depends on the characteristics of the boundary layer near the jet slot.

The Efficacy of Percutaneous Steroid Injection via Cricothyroid Membrane for Reinke's Edema (라인케씨 부종 환자에서 경윤상 갑상막 접근을 통한 성대 내 스테로이드 주입술의 효용)

  • Nam, Woojoo;Kim, Sun Woo;Jin, Sung Min;Lee, Sang Hyuk
    • Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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    • v.30 no.2
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    • pp.101-106
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    • 2019
  • Background and Objectives Reinke's edema is a benign vocal fold disease caused by an edematous laryngeal superficial layer of lamina propria. The first line treatment is cessation of smoking and laryngeal microsurgery. The aim of the study is to evaluate the feasibility and efficacy of percutaneous steroid injection via cricothyroid membrane in patients with Reinke's edema. Materials and Method From Jan 2010 to July 2018, 33 Patients with Reinke's edema managed by vocal fold steroid injection via the cricothyroid membrane were included in this study. We compared medical records of laryngoscopy, stroboscopy and Multi-Dimensional Voice Program analysis at pre-treatment and post-treatment. Subjective voice improvement was evaluated using Voice Handicap Index-30 (VHI-30). Results 75.7% of the patients showed partial response and 6.06% showed complete response. 93.94% were present smokers and only 4 patients ceased smoking after the treatment. In acoustic analysis, the pre-treatment mean value of jitter, shimmer, and noise to harmonic ratio was 2.30±3.21, 9.34±10.37, 1.11±2.90 each. The post-treatment value was 2.20±1.89, 6.96±5.30, 0.20±0.09 respectively and none of the parameters were statistically significant. For subjective symptom improvement, 25 (75.8%) patients showed a better score on post-treatment VHI-30 compared to pre-treatment. Conclusion According to our study, steroid injection is a relatively safe and effective procedure for patients with Reinke's edema. A vocal fold steroid injection via the cricothyroid membrane can be an alternative treatment option for those who are not able to undergo conventional laryngeal microscopic surgery, however cessation of smoking is necessary for effective treatment.

Numerical analysis of thermal post-buckling strength of laminated skew sandwich composite shell panel structure including stretching effect

  • Katariya, Pankaj V.;Panda, Subrata Kumar
    • Steel and Composite Structures
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    • v.34 no.2
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    • pp.279-288
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    • 2020
  • The computational post-buckling strength of the tilted sandwich composite shell structure is evaluated in this article. The computational responses are obtained using a mathematical model derived using the higher-order type of polynomial kinematic in association with the through-thickness stretching effect. Also, the sandwich deformation behaviour of the flexible soft-core sandwich structural model is expressed mathematically with the help of a generic nonlinear strain theory i.e. Green-Lagrange type strain-displacement relations. Subsequently, the model includes all of the nonlinear strain terms to account the actual deformation and discretized via displacement type of finite element. Further, the computer code is prepared (MATLAB environment) using the derived higher-order formulation in association with the direct iterative technique for the computation of temperature carrying capacity of the soft-core sandwich within the post-buckled regime. Further, the nonlinear finite element model has been tested to show its accuracy by solving a few numerical experimentations as same as the published example including the consistency behaviour. Lastly, the derived model is utilized to find the temperature load-carrying capacity under the influences of variable factors affecting the soft-core type sandwich structural design in the small (finite) strain and large deformation regime including the effect of tilt angle.

Extended Epitympanotomy for Facial Nerve Decompression as a Minimally Invasive Approach

  • Chao, Janet Ren;Chang, Jiwon;Lee, Jun Ho
    • Journal of Audiology & Otology
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    • v.23 no.4
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    • pp.204-209
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    • 2019
  • For a minimally invasive approach to access the facial nerve, we designed an extended epitympanotomy via a transmastoid approach that has proven useful in cases of traumatic facial nerve palsy and pre-cholesteatoma. To evaluate the surgical exposure through an extended epitympanotomy, six patients with traumatic facial nerve palsy were enrolled in this study. The same surgical technique was used in all patients. Patients were assessed and the degree of facial nerve paralysis was determined prior to surgery, 1-week post-operatively, and 6-months post-operatively using the House-Brackmann grading system. In all cases, surgical exposure was adequate. All patients with traumatic facial nerve palsy were male and the age range was 13 to 83 years. In all cases, the location of the facial nerve damage was limited to the area between the first and second genu. Symptoms of all the patients improved by 6 months post-operation (p=0.024). There were no complications in any of the patients. Extended epitympanotomy is useful for safe, rapid surgical exposure of the attic area, sparing the patient post-operative dimpling, skin incision complications, and lengthy exposure to anesthesia. We suggest that surgery for patients with facial nerve palsy secondary to trauma be performed using this described technique.

Extended Epitympanotomy for Facial Nerve Decompression as a Minimally Invasive Approach

  • Chao, Janet Ren;Chang, Jiwon;Lee, Jun Ho
    • Korean Journal of Audiology
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    • v.23 no.4
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    • pp.204-209
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    • 2019
  • For a minimally invasive approach to access the facial nerve, we designed an extended epitympanotomy via a transmastoid approach that has proven useful in cases of traumatic facial nerve palsy and pre-cholesteatoma. To evaluate the surgical exposure through an extended epitympanotomy, six patients with traumatic facial nerve palsy were enrolled in this study. The same surgical technique was used in all patients. Patients were assessed and the degree of facial nerve paralysis was determined prior to surgery, 1-week post-operatively, and 6-months post-operatively using the House-Brackmann grading system. In all cases, surgical exposure was adequate. All patients with traumatic facial nerve palsy were male and the age range was 13 to 83 years. In all cases, the location of the facial nerve damage was limited to the area between the first and second genu. Symptoms of all the patients improved by 6 months post-operation (p=0.024). There were no complications in any of the patients. Extended epitympanotomy is useful for safe, rapid surgical exposure of the attic area, sparing the patient post-operative dimpling, skin incision complications, and lengthy exposure to anesthesia. We suggest that surgery for patients with facial nerve palsy secondary to trauma be performed using this described technique.