• Title/Summary/Keyword: verifications

Search Result 271, Processing Time 0.025 seconds

SNP and Expression Analyses of Myostatin Gene in Korean Cattle (Hanwoo) (한우 myostatin 유전자의 SNP 및 발현분석)

  • Yu, Seong-Lan;Jung, Kie-Chul;Sang, Byung-Chan;Lee, Jun-Heon
    • Korean Journal of Agricultural Science
    • /
    • v.31 no.2
    • /
    • pp.97-104
    • /
    • 2004
  • Myostatin is a transforming growth and differentiation factor-${\beta}$ family member that acts as a negative regulator of muscle growth. Previously, mutations in the myostatin gene were known to be related to double muscling phenotypes in cattle. Because myostatin gene is highly related to muscle mass, also meat quality, in cattle, we sequenced whole myostatin mRNA and investigated the SNPs (Single Nucleotide Polymorphisms) in Korean cattle (Hanwoo). The results indicated that Hanwoo had an SNP in nt2385 and this mutation can be a useful marker with further verifications. We also investigated expression patterns of the myostatin gene from various muscle tissues and organs. Northern blotting results indicated that myostatin expression was restricted in muscles with variable expression levels. The results presented here can be used as a valuable information for meat quality related traits and muscle mass in cattle.

  • PDF

Undrained Analysis of Soft Clays Using an Anisotropic Hardening Constitutive Model: I. Constitutive Model (비등방경화 구성모델을 적용한 연약 지반의 비배수 거동 해석: I. 구성모델)

  • 오세붕
    • Journal of the Korean Geotechnical Society
    • /
    • v.15 no.6
    • /
    • pp.121-130
    • /
    • 1999
  • The objective of this study is to perform finite element analyses(FEA) using the anisotropic hardening constitutive model on the basis of the total stress concept. An anisotropic hardening model was then developed to solve the problem and its mathematical formulations and experimental verifications were also described. In a companion paper, the constitutive equation will be formulated for accurate and efficient solutions of FEA, and coded into a nonlinear analysis program, and finally a field problem will be analyzed. The proposed model includes the failure criterion of a von Mises type and the anisotropic hardening rule based on the generalized isotropic hardening description, which can model the nonlinearity and the anisotropy of the stress-strain relationship. As a result this study could verty the experimental results for UU triaxial tests, CU triaxial tests for overconsolidated samples, and anisotropic loading tests with the rotation of principal stress axes for $K_0$consolidated samples.

  • PDF

Verification of the Korean Version of the Dental Fear Survey

  • Kim, Ah-Hyeon;Ahn, Eun-Suk;An, So-Youn
    • Journal of Dental Anesthesia and Pain Medicine
    • /
    • v.19 no.6
    • /
    • pp.361-367
    • /
    • 2019
  • Background: Although studies on dental fear in relation to sex and age have been conducted, there have been few nationwide studies particularly on the youth sector. In addition, no validity and reliability verifications have been implemented for new research groups on the Korean version of the Dental Fear Survey (K-DFS). Therefore, this study aimed to apply the K-DFS developed in a previous study on Korean youth to draw conclusions on dental fear among the youth. Methods: This study used the K-DFS, a Korean translation of Kleinknecht's Dental Fear Survey for elementary school, middle school, and high school students. This study selected 2,161 young people of various ages as participants and increased the validity of the research results by expanding nationwide the scope of the study area. Results: Differences in fear levels according to sex were higher in boys fear behavior scores than in girls' regarding dental treatment (P < 0.05). Students with dental fear had higher scores on items associated with dental treatment and fear of dental stimuli compared with students without dental fear (P < 0.05). Differences were observed among the three groups (P < 0.05). However, the results of logistic regression analysis showed no statistically significant differences for dental visits based on sex, grade, and other subcomponents (P > 0.05). Conclusion: By verifying the validity of the newly developed K-DFS, this research confirmed its utility as a dental fear questionnaire. Therefore, there can be no objection that the grounds for criticism have been established according to conventional wisdom. In the future, however, developing and studying the limits of K-DFS that overcome the factors of dental fear, especially pain, will help reduce dental fear in adolescents.

Development of Designation Criteria for Ecological Protected Areas and its Application Methodology (생태계 보호지역의 합리적 지정을 위한 평가방법의 개발과 적용방안)

  • Park, Yong-Ha;Lee, Hyun-Woo;Kim, Ki-Gyoung;Lee, Gwan-Gyu;Choi, Jae-Yong;Heo, Soo-Jin;Seo, Gyoung-Won
    • Journal of Environmental Impact Assessment
    • /
    • v.17 no.3
    • /
    • pp.177-188
    • /
    • 2008
  • Attempts to develope designation criteria for ecological protected areas were made for rational and scientific designation and management of 'ecosystem and landscape conservation areas', 'wetland protection areas', 'special islands protection areas', and 'wildlife protected areas' which have been designated and managed by the Ministry of Environment. Through analysis of the requisites and criteria of IUCN, UNESCO, Natura 2000, the Ramsar convention, the United States, the United Kingdom, Japan, and Germany as well as various academic researches, evaluation items of the protected areas were classified into naturalness, biodiversity, ecosystem, and scientific values. These classification titles are reflection of Korean laws concerning the 4 protected areas described above. Of these items 'naturalness' is composed of 3 factors of wilderness, geomorphology and landscape, and vegetation. 'Biodiversity' is composed of the 5 factors of species diversity, endangered species, rare species, indigenous biological resources, and habitat of wetland wild animals. 'Ecosystem' is composed of 5 factors of typicalness, diversity, rarity, restoration ability, and degree of interference. All factors are scored using a 3 point scale of high, middle, or low and are then transformed into the numerical index for designating and zoning purposes. Conclusively, it is expected that the developed methodology will be highly applicable with field verifications.

Probabilistic Neural Network for Prediction of Compressive Strength of Concrete (콘크리트 압축강도 추정을 위한 확률 신경망)

  • Kim, Doo-Kie;Lee, Jong-Jae;Chang, Seong-Kyu
    • Journal of the Korea institute for structural maintenance and inspection
    • /
    • v.8 no.2
    • /
    • pp.159-167
    • /
    • 2004
  • The compressive strength of concrete is a criterion to produce concrete. However, the tests on the compressive strength are complicated and time-consuming. More importantly, it is too late to make improvement even if the test result does not satisfy the required strength, since the test is usually performed at the 28th day after the placement of concrete at the construction site. Therefore, strength prediction before the placement of concrete is highly desirable. This study presents the probabilistic technique for predicting the compressive strength of concrete on the basis of concrete mix proportions. The estimation of the strength is based on the probabilistic neural network which is an effective tool for pattern classification problem and gives a probabilistic result, not a deterministic value. In this study, verifications for the applicability of the probabilistic neural networks were performed using the test results of concrete compressive strength. The estimated strengths are also compared with the results of the actual compression tests. It has been found that the present methods are very efficient and reasonable in predicting the compressive strength of concrete probabilistically.

Genotype Analysis of apoVLDL-II Gene in Korean Chicken Breeds (한국 재래닭의 경제형질 개량을 위한 apoVLDL-II 유전자의 유전자형 분석)

  • Jung, K.C.;Lee, Y.J.;Bhuiyan, M.S.A.;Jang, B.K.;Choi, K.D.;Lee, J.H.
    • Korean Journal of Poultry Science
    • /
    • v.35 no.4
    • /
    • pp.335-339
    • /
    • 2009
  • The very low density apolipoprotein-II (apoVLDL-II) gene is closely related with the constitution of the lipoprotein in various tissues. The apoVLDL-II gene have main functions for reducing fat elements from tissues and muscles. Previous results indicated that the polymorphisms in apoVLDL-II gene were positively related with growth and body composition traits in chicken. In this study, we analyzed previously identified apoVLDL-II gene polymorphisms using the PCR-RFLP method and investigated allele and genotype frequencies in three chicken breeds. Data indicated that Korean native chicken and Korean Oge chicken have similar B and F gene frequencies, indicating that this marker can be used for the improvement of growth and body composition traits in those breeds and can be used as marker assisted selection with further verifications.

A Study on the Survey for the Application Status and the Improvement of Korean Medical Health Insurance for Ob & GY Disease ( II ) (부인과 질환에 대한 한방건강보험 적용실태 및 개선방안에 대한 조사연구 2)

  • Choi, Min-Sun;Kim, Dong-Il
    • The Journal of Korean Obstetrics and Gynecology
    • /
    • v.21 no.1
    • /
    • pp.150-167
    • /
    • 2008
  • Purpose: This is a following study of preceding study about application and improvement of acupuncture benefits in OB & GY disease that was performed in 2007. And this study was performed to complement and compare with a preceding study. Methods: The questionnaire used in preceding survey was distributed to general korean medical doctors who have mainly worked in oriental medical clinic. And results of this survey was compared with results of preceding survey. Results: Results of two surveys were almost similar. 1. The common suitable the sick and wounded name of Ob & Gy disease thought be added in Intra-abdominal acupuncture(腹腔內; CV13 ${\cdot}$ CV16 ${\cdot}$ CV10) in two surveys were dysmenorrhea(K05). infertility(K15), JingHa(pelvic tumor) (K11). In Puncture each adjoining acu-points in one insertion(透刺; SP6-GB39)were dysmenorrhea(K05), climacteric syndrome(K04). amenorrhea (K03), In Puncture each adjoining acu-points in one insertion(透刺; PC6-TE5) were climacteric syndrome(K04), hyperemesis(K16.0), dysmenorrhea(K05). 2. The common acupuncture benefits items that postpartum pain syndrome(K29) should be added as suitable the sick and wounded name were Intra-articular acupuncture(關節內; LI15, SI10, GB30), Intervertebral acupuncture (脊椎間; GV14, 16, 6, 4, 12, 11, 9, 8, 3), Puncture each adjoining acu-points in one insertion (透刺; SP6-GB39). Conclusion: Based on this study, Survey to more KMDs should be performed. And the academic and clinical verifications that supports this results should be supplied.

  • PDF

A Simplified Series-Parallel Structure for the RPPT (Regulated Peak Power Tracking) system (저궤도 인공위성용 Regulated Peak Power Tracking(RPPT) 시스템을 위한 단순화된 직-병렬 구조)

  • Yang, Jeong-Hwan;Bae, Hyun-Su;Lee, Jea-Ho;Cho, Bo-Hyung
    • The Transactions of the Korean Institute of Power Electronics
    • /
    • v.13 no.2
    • /
    • pp.110-118
    • /
    • 2008
  • The regulated peak power tracking (RPPT) systems such as the series structure and the parallel structure are commonly used in the satellite space power system. However, this structure processes the solar array power to the load through two regulators during one orbit cycle, which reduces the energy transfer efficiency. The series-parallel structure for the RPPT system can improve the power conversion efficiency, but an additional regulator increases the cost, size and weight of the system. In this paper, a simplified series-parallel space power system that consists of two regulators is proposed. The proposed system has the similar energy transfer efficiency with the series-parallel structure by adding one switch to the series structure, which reduces the cost, size and the weight. The large signal stability analyses is provided to understand the four main modes of system operation. In order to compare the energy efficiency with a series structure, the simulation is performed. The experimental verifications are performed using a prototype hardware with TMS320F2812 DSP and 200W solar arrays.

Cumulative Angular Distortion Curve of Multi-Pass Welding at Thick Plate of Offshore Structures

  • Ha, Yunsok;Choi, Jiwon
    • Journal of Advanced Research in Ocean Engineering
    • /
    • v.1 no.2
    • /
    • pp.106-114
    • /
    • 2015
  • In the fabrication of offshore oil and gas facilities, the significance of dimension control is growing continuously. But, it is difficult to determine the deformation of the structure during fabrication by simple lab tests due to the large size and the complicated shape. Strain-boundary method (a kind of shrinkage method) based on the shell element was proposed to predict the welding distortion of a structure effectively. Modeling of weld geometry in shell element is still a difficult task. In this paper, a concept of imaginary temperature pair is introduced to handle the effect of geometric factors such as groove shape, plate thickness and pass number, etc. Single pass imaginary temperature pair formula is derived from the relation between the groove area and the FE mesh size. By considering the contribution of each weld layer to the whole weldment, multi-pass imaginary temperature is also derived. Since the temperature difference represents the distortion increment, cumulative distortion curve can be drawn by integrating the temperature difference. This curve will be a useful solution when engineers meet some problems occurred in the shipyard. A typical example is shown about utilization of this curve. Several verifications are conducted to examine the validity of the proposed methodology. The applicability of the model is also demonstrated by applying it to the fabrication process of the heavy ship block. It is expected that the imaginary temperature model can effectively solve the modeling problem in shell element. It is also expected that the cumulative distortion curve derived from the imaginary temperature can offer useful qualitative information about angular distortion without FE analysis.

A Study on a Plan to Activate the Space of Small-Scale Art Museums by Using Space Analysis Program - Focused on Body Movement Elements - (공간분석 프로그램을 활용한 소규모 미술관의 공간 활성화 방안 연구 - 신체의 운동 요소를 중심으로 -)

  • Choi, Jin-Seok;Kim, Moon-Duck
    • Korean Institute of Interior Design Journal
    • /
    • v.24 no.3
    • /
    • pp.59-68
    • /
    • 2015
  • As the economical and cultural levels become higher, the public have more various and new cultural desires, leading to an increase in the number and kinds of cultural facilities. Out of all the cultural facilities built in such a trend, art museums are the yardstick for a certain nation's cultural level, and the number of art museums is gradually increasing every year in Korea, as a cultural space where the public can make cultural exchanges with artists. On the contrary to the increasing number of art museums, however, the number of art museum visitors is decreasing every year, so various attempts are made to activate art museums in Korea. Thus, this study aims to seek a plan to activate the space of an art museum by improving the physical movement of art museum visitors, especially targeting small-sized ones out of all the art museums in Korea. For accurate analyses and verifications, this study used the visibility-ERAM program. As a result of analyses, this study found out and reconsidered several problems related to the space of art museums, and based on the results, the researcher could verify the related hypotheses, further comprehending possible errors of the proposed solution to those problems and supplement in a short period of time. Since such an analysis method and process has objective accuracy, it is expected that the results of this study will be used as basic data for future plans to activate the space of art museums.