• Asian-Australasian Journal of Animal Sciences
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• v.31 no.4
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• pp.489-498
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• 2018

Objective: Foot and mouth disease (FMD) and porcine reproductive and respiratory syndrome (PRRS) are major diseases that interrupt porcine production. Because they are viral diseases, vaccinations are of only limited effectiveness in preventing outbreaks. To establish an alternative multi-resistant strategy against FMD virus (FMDV) and PRRS virus (PRRSV), the present study introduced two genetic modification techniques to porcine cells. Methods: First, cluster of differentiation 163 (CD163), the PRRSV viral receptor, was edited with the clustered regularly interspaced short palindromic repeats-CRISPR-associated protein 9 technique. The CD163 gene sequences of edited cells and control cells differed. Second, short hairpin RNA (shRNAs) were integrated into the cells. The shRNAs, targeting the 3D gene of FMDV and the open reading frame 7 (ORF7) gene of PRRSV, were transferred into fibroblasts. We also developed an in vitro shRNA verification method with a target gene expression vector. Results: shRNA activity was confirmed in vitro with vectors that expressed the 3D and ORF7 genes in the cells. Cells containing shRNAs showed lower transcript levels than cells with only the expression vectors. The shRNAs were integrated into CD163-edited cells to combine the two techniques, and the viral genes were suppressed in these cells. Conclusion: We established a multi-resistant strategy against viral diseases and an in vitro shRNA verification method.

• Journal of Positioning, Navigation, and Timing
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• v.6 no.4
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• pp.195-203
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• 2017

A 2U cube satellite called SNUGLITE has been developed by GNSS Research Laboratory in Seoul National University. Its main mission is to perform actual operation by mounting dual-frequency global positioning system (GPS) receivers. Its scientific mission aims to observe space environments and collect data. It is essential for a cube satellite to control an Earth-oriented attitude for reliable and successful data transmission and reception. To this end, an attitude estimation and control algorithm, Attitude Determination and Control System (ADCS), has been implemented in the on-board computer (OBC) processor in real time. In this paper, the Extended Kalman Filter (EKF) was employed as the attitude estimation algorithm. For the attitude control technique, the Linear Quadratic Gaussian (LQG) was utilized. The algorithm was verified through the processor in the loop simulation (PILS) procedure. To validate the ADCS algorithm in the ground, the experimental verification via a single axis Hardware-in-the-loop simulation (HILS) was used due to the simplicity and cost effectiveness, rather than using the 3-axis HILS verification (Schwartz et al. 2003) with complex air-bearing mechanism design and high cost.

• Korean Security Journal
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• no.18
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• pp.143-167
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• 2009

As of entering the 21st century, a trend in the field of a private security industry among the advanced countries have been increased a qualification system and train session to meet the needs of professionalism. Intensifying the professionalism in Korea, education and train system has been initiated to change but the oligopoly market already formulated due to impractical selection standard and management of education system. Issuing certification and offering basic training through a designated institution for the purpose of improving quality of the private security industry worker, its practical effectiveness were lower than expectation. Rather certification-holder or security agency, institution or truster's rent-seeking behavior have been increased by occupational licensing system. The founded results, which were associated to problems in selecting and educating to the private security guard, in this study were that any verification has been initiated towards dual-system in official approval and structural problems in education system, and non-existence of verification for professionalism and management capability to security agency owner and its upper managerial level. Current a dual system in an officially authorized verification system and completion of security guard credential requested change to an unified official qualification verification system to solve those problems. Ranges of an applicant to the unified official qualification verification system should be extend to the whole population in the private security industry. Moreover, minimization of the dead-weigh loss, which is caused by oligopoly phenomenon while using its market-dominant status, increasement number of designated institution, which allows self-regulating competition, and endowment of autonomy, which is in selecting education and agency, were requested to solve the problems in selecting and educating to the private security guard. In order to minimize stated problems while maintaining objectiveness, a new manage and supervise institution, which is called a 'private security industry committee', should be establish. The private security industry committee is a formation of governance network which are participated from professional group to civil organization.

• Journal of Korea Port Economic Association
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• v.24 no.2
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• pp.209-239
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• 2008

The purpose of this paper is to investigate the effectiveness of Korean port investment by using the newly developed slack-based multi-year panel congestion model of DEA(Data Envelopment Analysis). Inputs[port investment amount, cargo handling capacity, and berthing capacity], and outputs[cargo handling amount, number of ship calls, revenue, and score of customer service satisfaction] are used during 1994-2004 for 20 Korean seaports. Empirical analysis identified congestion especially in port investment as input at the ports of Gunsan, and Busan in the all 3 models, and the ports of Pyungtag, Mogpo, Yeosu, and leju in over 2 models. Port investment induced the rapid increase of port efficiency from the ports of Masan, Incheon, Donghae, and Samcheok. Therefore other ports except these ports should examine the reason about the inefficiency of port investment by searching out the situation of each ports directly. The main policy implication based on the findings of this study is that The Ministry of Land, Transport and Maritime Affairs in Korea should introduce the new measurement way after reviewing the multi-year slack-based congestion approach when the amount of port investment for each port is decided.

• Korean journal of communication and information
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• v.55
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• pp.50-73
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• 2011

This paper investigates the effectiveness of Real-Name System on Internet, which has been applied to some Internet service provider bulletin boards in Korea. The goal of the Real-Name system on the Internet is controlling expression of slanderous or abusive language. The effectiveness of the regulation is dependent on the people's perceptions and attitude toward to the legislation. This empirical study examines the antecedents that affect the perceptions and attitude toward the regulation. Further, we investigate the relationships among variables such as internet public sphere participation, attitude to the regulations, and intention to choose detours. Results of regression analysis show that the younger and the more progressive individuals are, the more they oppose the implementation of the law. Also, it was found that people who have more political interest and participate more actively in public sphere via internet, tend to oppose the law. Structural equation models reveal that participation in online public sphere drives negative attitudes about the regulation. In addition, people with negative perceptions about the law tend to choose the detours such as 'cyber asylum' and 'service asylum'.

• Journal of Families and Better Life
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• v.28 no.6
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• pp.1-18
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• 2010

The purpose of this study is to develop and verify the effectiveness of a group art therapy program to help children from multicultural families adapt to school life by using Kinetic School Drawing(KSD). The result of this study showed that the group art therapy program of the multicultural family's children may have a positive effect in aiding their school life adaptation. The results showed considerable and statistical outcome in the fore and after drawing inspection of the dynamic KSD. Also, the size of the self-image became bigger and their expressions has been increased. The qualitative analysis also showed a huge change in dynamistic personal relationships due to the relationship with their peers with the same aged and the tutor. This study emphasizes the importance of the group art therapy program to be applied before children are admitted to school because of growing recognition of concern about the maladjustment of rapidly growing multicultural family's children. It is also suggests that the group art therapy program of growing multicultural family's children should be viewed with an ecological point of view.

• Journal of the Korean Society of Systems Engineering
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• v.10 no.2
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• pp.59-69
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• 2014

In the bidding stage of turn-key based plant construction contracts, owners provide design and performance basis for contractors instead of giving design drawing. To win the bid for a plant construction, the contractors should be obliged to satisfy and ensure owners'requirements such as design and performance basis in a plant construction project, In other words, owners imposes technical risk of the design to the contractors by specifying responsibility for the analysis and verification of the plant construction. Thus, it is very important that contracters make accurate and realistic basic design plan in a short period of time. To deal with such a situation, we propose a systems engineering approach for the analysis and management of the technical risk. Specifically, we first: 1) Analyzes technical risk related with the plant design information for the bidders, followed by 2) Developing stakeholder requirements for the basic engineering design, and 3) System requirements for dealing with technical risk. Also, in this paper, we proposed converting method from MOE(Measure of Effectiveness) to MOP(Measure of Performance) in the risk analysis. To show the effectiveness of the proposed method, we carried out a case study.

• Journal of the Korean Solar Energy Society
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• v.23 no.2
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• pp.81-90
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• 2003

UTAC(unglazed transpired air collector) system has unique advantage for space heating and tempering ventilation air over the conventional collector system such as flat plate and vacuum collector. UTAC can improve radiative and convective loss due to nonglazed component and enhanced plate surface configuration. and heating energy and its equivalent green house emission performance can be improved from the use of this like collector in building application. The Option D Calibration simulation approach of IPMVP(International Performance Measurement and Verification Protocol) in ESCO businesses has been recommended to use of the calibrated computer modules like these Energy-10. DOE2.1E and TRNSYS(transient system simulation). This study is to develop subroutine type-203 of TRNSYS15.2 program and appraise thermal performance of UTAC. With newely addeded subroutine type-203. 1) Thermal performance of unglazed transpired collector could be possible based on dimensionless variables such as efficiency and heat exchanger effectiveness. and 2) Assessement of energy consists of solar useful and insulation saving for UTAC could be possible.

• Smart Structures and Systems
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• v.16 no.6
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• pp.1003-1021
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• 2015

MR dampers have been proposed for the control of cable vibration of cable-stayed bridge in recent years due to their high performance and low energy consumption. However, the highly nonlinear feature of MR dampers makes them difficult to be designed with efficient semi-active control algorithms. Simulation study has previously been carried out on the cable-MR damper system using a semi-active control algorithm derived based on the universal design curve of dampers and a bilinear mechanical model of the MR damper. This paper aims to verify the effectiveness of the MR damper for mitigating cable vibration through a full-scale experimental test, using the same semi-active control strategy as in the simulation study. A long stay cable fabricated for a real bridge was set-up with the MR damper installed. The cable was excited under both free and forced vibrations. Different test scenarios were considered where the MR damper was tuned as passive damper with minimum or maximum input current, or the input current of the damper was changed according to the proposed semi-active control algorithm. The effectiveness of the MR damper for controlling the cable vibration was assessed through computing the damping ratio of the cable for free vibration and the root mean square value of acceleration of the cable for forced vibration.

• International Journal of Internet, Broadcasting and Communication
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• v.14 no.3
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• pp.230-242
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• 2022

The purpose of this study was to verify the effectiveness of the computerized cognitive rehabilitation program in which areas and to suggest effective ways to utilize the program in the future, being conducted for 20 college students. We lasted this study from May 3 to 23, 2021. As a result of analyzing the groups using the Computer-based Cognitive Rehabilitation Program (CoTras), in terms of the difference in accuracy for the case of visual perception group B was statistically significantly improved than group C(p<0.05). In the case of attention, memory, and orientation, there was no significant difference between groups(p>0.05). In the case of reaction time difference, there was no significant difference between groups in visual perception, concentration, memory, and orientation(p>0.05). And in order to improve attention and visual perception, it is recommended to conduct the program three times with a duration of 20 minutes, and in order to improve orientation and memory, it can be said that it is helpful to conduct one experiment for at least 30 minutes rather than conducting short and frequent experiments. Through this study, we found that it is effective to apply different times according to each area to improve cognitive function. In other words, depending on the purpose of which cognitive function is to be improved, the duration of the program should be applied differently.