• Title/Summary/Keyword: vascular system

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Histological study of the primo vascular system on the falciform ligament (Falciform ligament(간겸상인대)에서 관찰되는 프리모 조직의 조직학적 특성 연구)

  • Yeon, Sun-Hee;Kwon, O-Sang;Lee, Sae-Bhom;Cho, Seong-Jin;Choi, Kwang-Ho;Lee, Sang-Hun;Choi, Sun-Mi;Ryu, Yeon-Hee
    • Korean Journal of Oriental Medicine
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    • v.18 no.2
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    • pp.131-137
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    • 2012
  • Objectives : Primo vascular system is known to new circulatory system and suggested as a anatomical structure of meridian system. Primo-vessels are present throughout the whole body. The purpose of this study is to identify primo tissues taken from falciform ligament and to compare with organ surface primo tissue, blood vessel and lymph vessel. Methods : Male Sprague-Dawley rats (8weeks old, 250~320g) used for this study. The medial line of the abdomen was dissected and searched for primo tissues in falciform ligament and on the internal organs using stereomicroscope. We performed serial cross section and histological investigations. The tissues were stained with hematoxylin-eosin and Masson's trichrome. Results : 1. The primo tissues attached on the falciform ligament had white color and length of 5~8mm. 2. We could observe primo tissues are classified with ligament tissues. 3. Histologically, primo tissue on falciform ligament and organ surface primo tissue could be considered same tissue. Conclusions : In this study, we observed primo tissue discovered on the falciform ligament. And we also histologically compared such discovered primo tissue with organ surface primo tissue. Consequently, we could consider that two tissues have histological similarity and possibility of connection in one network system.

The Transcranial Doppler(TCD) Assesment of Vertebrobasal Vascular Blood Flow in Cerebral Infarction (Transcranial Doppler를 이용(利用)한 급성기뇌경색(急性期腦硬塞)이 추골기저동맥계(椎骨基底動脈係) 혈관(血管)의 혈류속도(血流速度)에 미치는 영향(影響))

  • Ahn, Teck-Won;Kim, Yoon-Sik
    • The Journal of Internal Korean Medicine
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    • v.21 no.5
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    • pp.805-811
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    • 2000
  • Objectives : To determine the effects on blood flow of vertebrobasal vascular system in cerebral infarction, Methods : We altered 33 normal patients and 12 patients who were diagnosed cerebral infarction on Rt. middle cerebral artery(MCA) region and 8 patients who were diagnosed cerebral infarction on Lt, MCA region, and measured the mean velocity, systolic to diastolic rate(SD rate), asymmetrical index(A/I) by TCD. Results : The mean velocity of posterior cerebral artery(PCA), vertebral artery was increased in same direction as infarcted site and the mean velocity of basal artery was more increased than control, and the SD rate of PCA, vertebral artery, basal artery was larger than control. The A/l of PCA, vertebral artery was revealed that mean velocity of vertebrobasal vascular system is increase the same direction as infarcted area. Conclusion : TCD examination within 7 days(acute stage) after stroke can help to predict the infarcted direction.

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Structure and function of vascular endothelial growth factor and its receptor system

  • Park, Seong Ah;Jeong, Mi Suk;Ha, Ki-Tae;Jang, Se Bok
    • BMB Reports
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    • v.51 no.2
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    • pp.73-78
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    • 2018
  • Vascular endothelial growth factor and its receptor (VEGF-VEGFR) system play a critical role in the regulation of angiogenesis and lymphangiogenesis in vertebrates. Each of the VEGF has specific receptors, which it activates by binding to the extracellular domain of the receptors, and, thus, regulates the angiogenic balance in the early embryonic and adult stages. However, de-regulation of the VEGF-VEGFR implicates directly in various diseases, particularly cancer. Moreover, tumor growth needs a dedicated blood supply to provide oxygen and other essential nutrients. Tumor metastasis requires blood vessels to carry tumors to distant sites, where they can implant and begin the growth of secondary tumors. Thus, investigation of signaling systems related to the human disease, such as VEGF-VEGFR, will facilitate the development of treatments for such illnesses.

Feasibility of simultaneous measurement of cytosolic calcium and hydrogen peroxide in vascular smooth muscle cells

  • Chang, Kyung-Hwa;Park, Jung-Min;Lee, Moo-Yeol
    • BMB Reports
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    • v.46 no.12
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    • pp.600-605
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    • 2013
  • Interplay between calcium ions ($Ca^{2+}$) and reactive oxygen species (ROS) delicately controls diverse pathophysiological functions of vascular smooth muscle cells (VSMCs). However, details of the $Ca^{2+}$ and ROS signaling network have been hindered by the absence of a method for dual measurement of $Ca^{2+}$ and ROS. Here, a real-time monitoring system for $Ca^{2+}$ and ROS was established using a genetically encoded hydrogen peroxide indicator, HyPer, and a ratiometric $Ca^{2+}$ indicator, fura-2. For the simultaneous detection of fura-2 and HyPer signals, 540 nm emission filter and 500 nm~ dichroic beamsplitter were combined with conventional exciters. The wide excitation spectrum of HyPer resulted in marginal cross-contamination with fura-2 signal. However, physiological $Ca^{2+}$ transient and hydrogen peroxide were practically measurable in HyPer-expressing, fura-2-loaded VSMCs. Indeed, distinct $Ca^{2+}$ and ROS signals could be successfully detected in serotonin-stimulated VSMCs. The system established in this study is applicable to studies of crosstalk between $Ca^{2+}$ and ROS.

Tissue Specific Expression of Wound-Inducible RCaM-2 Promoter in Transgenic Tobacco Plants (상처에 의해서 유도되는 벼 calmodulin promoter의 transgenic 담배에서조직 특이적 발현)

  • Choi Young Ju
    • Journal of Life Science
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    • v.15 no.2 s.69
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    • pp.176-181
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    • 2005
  • To study calmodulin (CaM) gene expression and its regulation, rice CaM promoter (RCaM-2) was isolated and fused to $\beta-glucuronidase$ (GUS), reporter gene. X-Glue staining patterns revealed that GUS localization is high in meristemic tissues such as the stem apex, stolen tip, and vascular regions. GUS staining in the transverse sections of stem and petiole was restricted to the inside of the vascular system, and cortex and epidermis located outside of the vascular system usually did not show GUS staining even a plant that expressed strong activity. GUS activity was found to be tissue specific expressed and exhibited a dramatic transient increase in response to wounding. These results suggest that the 5'-flanking region of RCaM gene regulates wound-inducible expression.

The Characteristic of Vascular Plants in Cornus officinalis Farmland in Gurye which Designated as Korea's Important Agricultural Heritage System (국가중요농업유산 구례 산수유 농업지의 관속식물상 특성)

  • Kim, Jin-Won;Oh, Choong-Hyeon
    • Journal of Korean Society of Rural Planning
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    • v.24 no.2
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    • pp.101-107
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    • 2018
  • This study has been conducted to understand the relationships such as interspecific interactions between species and landscapes within and outside of agricultural land by identifying the flora features of Cornus officinalis farmlands in Gurye which designated as Korea's Important Agricultural Heritage System. For this, the flora of vascular plants was surveyed in every land uses of two representative districts. These two districts represent the own features of Cornus officinalis farming area which including land uses like forests(especially pine tree), valley, farmland(rice paddy, farms, Cornus officinalis farmland), and residence. Also differences in flora by stone wall's existence and Cornus officinalis's DBH were surveyed. As a result, Cornus officinalis farmlands showed the various vascular plants than the other land uses. According to the existence of stone wall in Cornus officinalis farmlands, there were no differences in appearance flora. But the flora in Cornus officinalis farmlands which have different Cornus officinalis' DBH(Divided into average over 15cm and under 8cm), various plants were showed in average over 15cm than average under 8cm. In conclusion, Cornus officinalis farmlands have been actively engaged in various types of land use and species exchanges, including forests, valleys, villages, and fields, and it has been confirmed that it acts as an ecological axis connecting forests to villages.