• Mass Spectrometry Letters
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• v.14 no.3
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• pp.57-78
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• 2023

Understanding the chemical composition of the brain helps researchers comprehend various neurological processes effectively. Understanding of the fundamental pathological processes that underpin many neurodegenerative disorders has recently advanced thanks to the advent of innovative bioanalytical techniques that allow high sensitivity and specificity with chemical imaging at high resolution in tissues and cells. Mass spectrometry imaging [MSI] has become more common in biomedical research to map the spatial distribution of biomolecules in situ. The technique enables complete and untargeted delineation of the in-situ distribution characteristics of proteins, metabolites, lipids, and peptides. MSI's superior molecular specificity gives it a significant edge over traditional histochemical methods. Recent years have seen a significant increase in MSI, which is capable of simultaneously mapping the distribution of thousands of biomolecules in the tissue specimen at a high resolution and is otherwise beyond the scope of other molecular imaging techniques. This review aims to acquaint the reader with the MSI experimental workflow, significant recent advancements, and implementations of MSI techniques in visualizing the anatomical distribution of neurochemicals in the human brain in relation to various neurogenerative diseases.

• Journal of Dental Anesthesia and Pain Medicine
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• v.24 no.4
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• pp.265-272
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• 2024

Effective pain management is crucial for the successful performance of various endodontic procedures. Painless treatments are made possible by anesthetizing the tooth to be treated using various nerve-block techniques. However, certain circumstances necessitate supplemental anesthetic techniques to achieve profound anesthesia, especially in situations involving a "hot tooth" in which intrapulpal anesthesia (IPA) is employed. IPA is a technique that involves the injection of an anesthetic solution directly into the pulp tissue and is often utilized as the last resort when all other anesthetic techniques have been unsuccessful in achieving complete pulpal anesthesia. This review focuses on the IPA procedure and the factors that influence its success. Additionally, the advantages, limitations, disadvantages, and future directions of IPA are discussed.

• JSTS:Journal of Semiconductor Technology and Science
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• v.10 no.4
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• pp.292-299
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• 2010

With scaled technology, timing analysis of circuits becomes more and more difficult. In this paper, we review recently developed circuit simulation techniques created to deal with the cost issues of transistor-level simulations. Various techniques for fast SPICE simulations and Monte Carlo simulations are introduced. Moreover, process and aging variation issues are mentioned, along with promising methodologies.

• Journal of Korean Society for Quality Management
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• v.26 no.4
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• pp.219-238
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• 1998

The objective of this study was to establish a procedure of concurrent engineering which can be easily a, pp.icable in Korean industry. An investigation of various techniques of concurrent engineering was conducted. Problems of Korean companies which can be resolved by concurrent engineering techniques were identified. Techniques which can resolve these problems at the relatively low cost and without complicated computer facilities were selected and form a procedure for this study. The procedure was a, pp.ied to a manufacturing company for validation. It was found that this procedure can substantially reduce time and cost of R&D and manufacturing.

• Economic and Environmental Geology
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• v.29 no.2
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• pp.207-214
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• 1996

For many years oxygen and hydrogen isotope analysis have been used as one of the most valuable research tools to investigate many geological processes. There are many sample preparation techniques of oxygen and hydrogen isotope analysis for various geological samples. We introduce here several important sample preparation techniques for oxygen and hydrogen isotope analysis and discuss the problems of each method in detail.

• Korean Journal of Geomatics
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• v.3 no.1
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• pp.23-32
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• 2003

Rigorous sensor and dynamic modeling techniques are required if spatial information is to be accurately extracted from video imagery. First, a mathematical model for an uncalibrated video camera and a description of a bundle adjustment with added parameters, for purposes of general block triangulation, is presented. This is followed by the application of invariance-based techniques, with constraints, to derive initial approximations for the camera parameters. Finally, dynamic modeling using the Kalman Filter is discussed. The results of various experiments with real video imagery, which apply the developed techniques, are given.

• Journal of the Korean Society of Visualization
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• v.2 no.1
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• pp.52-56
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• 2004

Several visualization techniques of laser diagnostics are presented for combustion phenomena, including Mie scattering for flow, Rayleigh and Raman scattering spectroscopy for major species, laser-induced fluorescence for minor species, and laser-induced incandescence for soot. These techniques have been applied to understand the various combustion phenomena more clearly, including buoyancy-dominant flow system, diffusion flam oscillation, laminar and turbulent lifted flames, flame propagation along a vortex ring, and soot zone characteristics. The usefulness of laser diagnostics on a better understanding of physical mechanism is demonstrated.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 1990.10a
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• pp.91-94
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• 1990

The object of this study is to develop computer programs with which ordinary engineers can analyse or design steel-concrete composite teams using optimization technique. Various design ana construction techniques which could maximize load carrying capacities and control concrete tension cracks effectively are studied and included in the programs. Analysis results show that proposed construction techniques can reduce steel weight by about 10%∼20% compared with ordinary composite beam. Concrete tensile stresses can also be controlled affectively by the suggested techniques.

• Korean Journal of Optics and Photonics
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• v.1 no.1
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• pp.87-97
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• 1990

With the recent advent of various ultrashort pulse lasers, time-resolved laser spectroscopic techniques have been widely recognized as versatile tools to study ultrafast phenomena in many research areas. These techniques are currently being employed not only to study atomic and molecular physics but to characterize the excited state or the carrier dynamics on surfaces of semiconductors, metals and thin layer materials. Also the sweetching speed measurement of ultrafast electro-optic devices using ultrashort laser pulses becomes important in high-speed electronics. Here, some principles of spectroscopic techniques with ps or fs lasers and their applications are summarized briefly.

• Journal of Power Electronics
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• v.17 no.5
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• pp.1244-1255
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• 2017

The space vector pulse width modulation (SVPWM) technique is a popular PWM method for medium voltage drive applications. Conventional SVPWM (CSVPWM) and bus clamped SVPWM (BCSVPWM) are the most common SVPWM techniques. This paper evaluates the performance of various advanced BCSVPWM strategies in terms of their harmonic distortion and switching loss based on a uniform frame work. A uniform frame work, pulse number captures the performance parameter variations of different SVPWM strategies for various number of samples with heterogeneous pulse numbers. This work compares different advanced BCSVPWM techniques based on the modulation index and location of the clamping position (zero vector changing angle ) of a phase in a line cycle. The frame work provides a fixed fundamental frequency of 50Hz. The different BCSVPWM switching strategies are implemented and compared experimentally on a 415V, 2.2kW, 50Hz, 3-phase induction motor drive which is fed from an IGBT based 2 KVA voltage source inverter (VSI) with a DC bus voltage of 400 V. A low cost PIC microcontroller (PIC18F452) is used as the controller platform.