• Genomics & Informatics
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• v.10 no.2
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• pp.110-116
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• 2012

Recent several studies have shown that the genetic variation of SCN5A is related with atrioventricular conduction block (AVB); no study has yet been published in Koreans. Therefore, to determine the AVB-associated genetic variation in Korean patients, we investigated the genetic variation of SCN5A in Korean patients with AVB and compared with normal control subjects. We enrolled 113 patients with AVB and 80 normal controls with no cardiac symptoms. DNA was isolated from the peripheral blood, and all exons (exon 2-exon 28) except the untranslated region and exon-intron boundaries of the SCN5A gene were amplified by multiplex PCR and directly sequenced using an ABI PRISM 3100 Genetic Analyzer. When a variation was discovered in genomic DNA from AVB patients, we confirmed whether the same variation existed in the control genomic DNA. In the present study, a total of 7 genetic variations were detected in 113 AVB patients. Of the 7 variations, 5 (G87A-A29A, intervening sequence 9-3C>A, A1673G-H558R, G3578A-R1193Q, and T5457C-D1819D) have been reported in previous studies, and 2 (C48G-F16L and G3048A-T1016T) were novel variations that have not been reported. The 2 newly discovered variations were not found in the 80 normal controls. In addition, G298S, G514C, P1008S, G1406R, and D1595N, identified in other ethnic populations, were not detected in this study. We found 2 novel genetic variations in the SCN5A gene in Korean patients with AVB. However, further functional study might be needed.

• Journal of Bio-Environment Control
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• v.17 no.3
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• pp.210-214
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• 2008

This experiment was carried out investigation of optimum concentration of supply nutrient solution in hydroponics of sweet pepper using coir substrates (coconut dust fiber=70% : 30%, v/v). During the growing period, it was found out that the electric conductivity (EC) would increase in proportion to the supply nutrient concentration but it was in inverse proportion to the moisture content. The pH of drainage was stable, while EC was high showing EC $7.3\;dS{\cdot}m^{-1}$ in EC $4.0\;dS{\cdot}m^{-1}$ of supply nutrient concentration. Also, standard deviation and coefficient of variation were high. Plant length was no difference by the supply nutrient concentration. Photosynthesis rate was generally high in supply nutrient concentration EC$4.0\;dS{\cdot}m^{-1}$. Fruit weight was heavy in supply nutrient concentration EC $4.0\;dS{\cdot}m^{-1}$, fruit shape was close to a regular square in supply nutrient concentration EC $3.5dS{\cdot}m^{-1}$.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2018.10a
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• pp.514-516
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• 2018

We have investigated the effect of interface trap charge on the characteristics of a monolithic 3D inverter by TCAD simulation. The interface trap charge affects the variation of the threshold voltage and threshold voltage. also The interface trap charge affects the IN/OUT characteristics of the monolithic 3D inverter.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.33 no.3
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• pp.1027-1035
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• 2013

In this study, two rainfall patterns are utilized for practical consideration of rainfall phenomena in unsaturated soil slope design. One is the I.D.F (Intensity-Duration-Frequency) method which is an existing design rainfall method and ignores the effect of the variation of the rainfall according to the time. The other is the Huff method which considers this effect oppositely. First, the safety of factor of the slope according to the variation of an initial suction which means the precedent rainfall effect was examined by means of the application of the I.D.F method. Through the application of two rainfall patterns, it was discussed how the rainfall pattern affects the factor of safety of the slope. As a result, it is found that the Huff method is more practical on the evaluation of the slope stability than the I.D.F method.

• Bulletin of the Korean Chemical Society
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• v.33 no.2
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• pp.663-669
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• 2012

The nucleophilic substitution reactions of dibutyl chlorophosphate (3) with substituted anilines ($XC_6H_4NH_2$) and deuterated anilines ($XC_6H_4ND_2$) are investigated kinetically in acetonitrile at $55.0^{\circ}C$. The obtained deuterium kinetic isotope effects (DKIEs; kH/kD) are secondary inverse ($k_H/k_D$ = 0.86-0.97) with the strongly basic anilines while primary normal ($k_H/k_D$ = 1.04-1.10) with the weakly basic anilines. The DKIEs, steric effects of the two ligands, activation parameters, cross-interaction constants, variation trends of the kH/kD values with X, and mechanism are discussed for the anilinolyses of the nine ($R_1O$)($R_2O$)P(=O)Cl-type chlorophosphates. A concerted mechanism is proposed with a backside nucleophilic attack transition state for the strongly basic anilines and with a frontside attack involving a hydrogen-bonded four-center-type transition state for the weakly basic anilines on the basis of the magnitudes, secondary inverse and primary normal, and variation trends of the $k_H/k_D$ values with X.

• Fashion & Textile Research Journal
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• v.9 no.6
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• pp.651-657
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• 2007

This study was carried out to analyse body configuration and to observe any space between skin and foundation. A special 3D scanner was used to analyze this foundation. Experimental foundations were brassiere, girdle, and all-in-one. Four subjects volunteered, each subject was scanned while wearing foundation and not wearing foundation. Body shape variations were analyzed with an Auto CAD and ScanWax program which analyzes cross section of the skin surface to look for any changes. Height was increased all parts of body, circumference was increased in breast and bust while wearing the foundation. The hip thickness was not increased with wearing the foundation. Therefore this foundation makes people have a different appearance due to unexpected body shape variations. The effects of this foundation should be classified by observing height, circumference, and thickness changes in the body.

• International Journal of Internet, Broadcasting and Communication
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• v.7 no.1
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• pp.57-61
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• 2015

The level of change in distant PTC, near PTC, distant NTC, and near NTC was measured divided by before and after viewing 3D images. The 50 examinees were categorized into Low/ Middle/ High groups according to the level of change by test subject. Among all the entries, the exophoria group showed the highest change distribution, and in the distant and near NTC entries showed statistically significant differences in variation.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.16 no.12
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• pp.1071-1076
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• 2003

The nonlinear properties and their stability of ZPCCD- based varistors, which are composed of ZnO P $r_{6}$ $O_{ll}$ - CoO-C $r_2$ $O_3$-D $y_2$ $O_3$-based ceramics, were investigated in the D $y_2$ $O_3$ content range of 0.0∼2.0 mol%. The incorporation of D $y_2$ $O_3$ greatly affected the nonlinear properties and the best nonlinearity was obtained from 0.5 mol% D $y_2$ $O_3$ with nonlinear exponent of 66.6 and leakage current of 1.2 $\mu$A. Further addition of D $y_2$ $O_3$ deteriorated the nonlinear properties. In stability against DC accelerated aging stress state: 0.95 $V_{1mA}$/15$0^{\circ}C$/24 h, the 0.5 mol％ D $y_2$ $O_3$-doped varistor exhibited the highest stability, in which the variation rate of varistor voltage and nonlinear exponent are -1.9% and 10.5%, respectively. The remainder varistors resulted in thermal runaway due to low density of ceramics.s.s.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.24 no.12
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• pp.2917-2925
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• 2000

Tensile strength and failure process of composite materials depend on the variation in fiber strength, matrix properties and fiber-matrix interfacial shear strength. A Monte-Carlo simulation considering variation in these factors has been widely used to analyze such a complicated phenomenon as a strength and simulated the failure process of unidirectional composites. In this study, a Monte Carlo simulation using 2-D and 3-D(square and hexagonal array) model was performed on unidirectional graphite/epoxy and glass/polyester composites. The results simulated by using 3-D hexagonal array model have a good agreement with the experimental data which were tensile strength and failure process of unidirectional composites.

• Journal of Korean Clinical Health Science
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• v.1 no.3
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• pp.33-37
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• 2013

Purpose. In this study, we divided elementary school students into two investigated groups. The A group is the lower graders(boys 9, girls 18), and the B group is the higher graders(boys 10, girls 13). The myopia progression has been compared with to each group and it has been investigated for variable terms. Methods. We have analyzed the refraction inspection record of 50 students(boys 19, girls 31) who visited optical shops and more than two times in one year. Results. The subject of study were 50 students(boys 19, girls 31). 1. The distribution of spherical equivalent power with ages : boys A group -2.42D, girls A group -2.53D, boys B group -2.63D, girls B group -2.78D. boys B group -2.63D, girls B group -2.78D. 2. The monthly variation of spherical equivalent power : -0.055D(A), -0.04D(B) in boys, and -0.065D(A), -0.07D(B) in girls. Conclusions. Considering monthly variations and Supposing that the time of changing spectacles degrees were the time of refracting inspection. The result : 3.8 month for A group, 4.5 month for B group in boys, and 3.5 month for A group, 5.2 month for B group in girls.