It is believed that traditional Korean medicines can be managed more scientifically through the development of logical criteria to verify their region of cultivation, and that this could contribute to the advancement of the traditional herbal medicine industry. This study attempted to determine such criteria for Sansuyu. The volatile compounds were obtained from 20 samples of domestic Corni fructus (Sansuyu) and 45 samples of Chinese Sansuyu by steam distillation. The metabolites were identified in the NIST Mass Spectral Library via the obtained gas chromatography/mass spectrometer (GC/MS) data of 53 training samples. Data binning at 0.2 min intervals was performed to normalize the number of variables used in the statistical analysis. Multivariate statistical analyses, such as principle component analysis (PCA), partial least squares-discriminant analysis (PLS-DA), and orthogonal partial least squares-discriminant analysis (OPLS-DA) were performed using the SIMCA-P software package. Significant variables with a variable importance in the projection (VIP) score higher than 1.0 were obtained from OPLS-DA, and variables that resulted in a p-value of less than 0.05 through one-way ANOVA were selected to verify the marker compounds. Finally, among the 11 variables extracted, 1-ethylbutyl-hydroperoxide (9.089 min), nonadecane (20.170 min), butylated hydroxytoluene (25.319 min), 5β,7βH,10α-eudesm-11-en-1α-ol (25.921 min), 7,9-bis(2-methyl-2-propanyl)-1-oxaspiro[4.5]deca-6,9-diene-2,8-dione (34.257 min), and 2-decyldodecyl-benzene (54.717 min) were selected as markers to indicate the origin of Sansuyu. The statistical model developed was suitable for the determination of the geographical origin of Sansuyu. The cultivation areas of four Korean and eight Chinese Sansuyu samples were predicted via the established OPLS-DA model, and it was confirmed that 11 of the 12 samples were accurately classified.
Servitization presents an innovative model to create business value in the automotive industries. This study set out to introduce a servitization model based on the rental business of the tire industry and identify determinants to affect the renewal of contracts around the service types of servitization and the characteristics of customers. Independent variables include the service types, demographics and regions, and inflow channels in 163,742 contracts by case companies in the nation in 2016~2019 with the renewal of contracts as a dependent variable. Correlations between variables were analyzed through cross-tabulation and binary logistic regression analysis. The findings show that the contract renewal rate had positive(+) relations with customized service and negative(-) ones with vehicle maintenance service. There were differences in the contract renewal rate according to such customer characteristics as gender and region, but no clear correlations were found in the age group and vehicle type(domestic/foreign). Of the inflow channels, offline channels tended to have a higher renewal rate than online channels. At open malls, contract renewal increased by 8.4 times due to contract switches at offline channels. Based on these findings, the study discussed directions for practical strategies with regard to the development of new service, implementation of customer-centric servitization, and management of sales channels according to the servitization of manufacturers.
Journal of Korean Society of Coastal and Ocean Engineers
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v.29
no.3
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pp.162-168
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2017
Shallow-water bathymetry survey has been conducted using high definition color images obtained at the altitude of 100 m above sea level using a drone. Shallow-water bathymetry data are one of the most important input data for the research of beach erosion problems. Especially, accurate bathymetry data within closure depth are critically important, because most of the interesting phenomena occur in the surf zone. However, it is extremely difficult to obtain accurate bathymetry data due to wave-induced currents and breaking waves in this region. Therefore, optical remote sensing technique using a small drone is considered to be attractive alternative. This paper presents the potential utilization of image processing algorithms using multi-variable linear regression applied to red, green, blue and grey band images for estimating shallow water depth using a drone with HD camera. Optical remote sensing analysis conducted at Wolpo beach showed promising results. Estimated water depths within 5 m showed correlation coefficient of 0.99 and maximum error of 0.2 m compared with water depth surveyed through manual as well as ship-board echo-sounder measurements.
Flood frequency estimate is an essential index for determining the scale of small and middle hydraulic structure. However, this flood quantity could not be estimated directly for practical design purpose due to the lack of available flood data, and indirect method like design rainfall-runoff method have been used for the estimation of design flood. To give the good explain for design flood estimates, regional flood frequency analysis was performed by flood index method in this study. First, annual maximum series were constructed by using the collected data which covers from Japanese imperialism period to 1999. Wakeby distribution recommended by WMO(1989) was used for regional flood frequency analysis and L-moment method by Hosking (1990) was used for parameter estimation. For the homogeneity of region, the discordance and heterogeneity test by Hosking and Wallis(1993) was carried for 4 major watersheds in Korea. Physical independent variable correlated with index flood was watershed area. The relationship between specific discharge and watershed area showed a type of power function, i.e. the specific discharge decreases as watershed area increases. So flood quantity according to watershed area and return period was presented for each watershed(Han rivet, Nakdong river, Geum river and Youngsan/Seomjin river) by using this relation type. This result was also compared with the result of point frequency analysis and its regionalization. It was shown that the dam construction couldn't largely affect the variation of peak flood. The property of this study was also examined by comparison with previous studies.
Hydrogeological modelling was performed to evaluate groundwater flow system in Igsan Area. The study area extends over $790km^2$. The geology consists of Jurassic Daebo granite and gneissose granite and Precambrian metamorphic rocks. The capability of pumping yield is the highest in gneissose granite region among them due to comparatively thick weathered zone with thickness ranging from 10m to 25m. The Colorado State University Finite Difference Model was used for the model simulation. The model was divided into 28 rows and 31 columns with variable grid spacing. The model was calibrated under steady-state and unsteady-state conditions. In the steady-state simulation, the model results were compared with measured water table contours in September 1985 with determining hydraulic conductivities and net recharge rates during rainy season. Unsteady state simulation was done to know the aquifer response due to groundwater abstraction. The non- steady state calibration was conducted to determine the distribution and magnitudes of specific yields and discharge/recharge rates during dry season as matching water level altitudes in May 1986. The calibrated model was used to simulate water level vaiation caused by groundwater withdrawal and natural recharge from 1 October, 1985 until 30 September, 1995. The calibrated model can be used to groundwater development schemes on regional groundwater levels, but it cannot be used to simulate local groundwater level change at a specific site.
This research aims at measuring images density of according to DAP(dose area product), and suggesting the need to quality control of exposure dose. When tube voltage was fixed as 80 kVp and tube current was set as 1, 25, 50, 80, and 100 mAs, with the increase of DAP from 25 mAs to 50 mAs, the dose also rose 1.88 times as much as before, and with the increase from 50 mAs to 100 mAs, it got 2.05 time higher than before. However, the images density obtained as film grew as much as 48% with the increase from 25 mAs to 50 mAs, and 29% with the increase from 50 mAs to 100 mAs. In addition, it has been found out that the higher the DR images density got from 25 mAs to 50 mAs, the bigger it became by 12%, and that it got bigger by 30% with the increase from 50 mAs to 100 mAs. In other words, the differences in the image density by the increase of the dose with the digital imaging equipment in a proper condition was proved to be less than in the film images. Based on the results of this research, medical institutions using a digital imaging equipment are expected to be able to reduce exposure dose of each region of interest than now through the quality control of radiation dose.
Kim, Hyun-Jeong;Kim, Suk;Gang, Hye-Yeong;Bang, Mi-Young
Journal of the Korean Society of School Health
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v.16
no.2
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pp.111-123
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2003
The purpose of this study was to identify the expectation about school health program of primary school parents as an important variable for growth of school health program fore area locked primary school parents 631 by self-administered questionnaire between June 20 and September 29, 2001 The results were as follows 1. General characteristic of the Subjects Age rates of the subjects were 45.5% on 35~39 years old and 34.7% over 40 years old. Economic status were middle level 86%, participation rates of school health education for parent were 16.8%, recognition rates on significance of school health education were 89.9%. 2. Health knowledge of parents The mean score on health knowledge of the subjects was 6.8 from a total of 10. there was a statistically significant difference with regard to health knowledge among the 7school(F=3.46, p=.016). 3. Health behavior of parents The mean score on health behaviors of the subjects was 77.3 from a total of 100. there was no statistically difference in health behavior among the school. 4. The expectation about school health program of the parents The mean score on the expectation about school health program of the subjects was 51.1 from a total of 140. there was a statistically significant difference with regard to the expe ctation about school health program among the school(F=3.75, p=.010). 5. Health behaviors and the expectation about school health program from sociod emogr aphic Backgrounds of the Subjects. In the backgrounds of the subjects, the score on health behavior was higher the mothers(t=2.89,p=.004), the upper class(F=7.38, p=.000), the higher participation level of school health education of parent(F=7.38, p=.000) and the higher recognition level on significance of school health education of parent(F=9.94, p=.000). The score on the expectation about school health program was higher the lower recognition level on significance of school, health education of parent and on the expectation about health screening & preventive services was significant difference by age. however, the difference was not significant in the others.
Rice yield (kg 10a-1) in South Korea was estimated by meteorological variables that are influential factors in crop growth. This study investigated the possibility of anticipating the rice yield variability using a simple but an efficient statistical method, a multiple linear regression analysis, on the basis of the annual variation of meteorological variables. Due to heterogeneous environmental conditions by region, the yearly rice yield was assessed and validated for each province in South Korea. The monthly mean meteorological data for the period 1986-2018 (33 years) from 61 weather stations provided by Korean Meteorological Administration was used as the independent variable in the regression analysis. An 11-fold (leave-three-out) cross-validation was performed to check the accuracy of this method estimating rice yield at each province. This result demonstrated that temporal variation of rice yield by province in South Korea can be properly estimated using such concise procedure in terms of correlation coefficient (0.7, not significant). Furthermore, the estimated rice yield well captured spatial features of observation with mean bias of 0.7 kg 10a-1 (0.15%). This method may offer useful information on rice yield by province in advance as long as accurate agro-meteorological forecasts are timely obtained from climate models.
Objective : We analysed diverse clinical features of the cavernous angioma. Also, we report the experience in differ-ent methods of the management and their results. Method : Data from 80 patients who were confirmed pathologically or diagnosed radiologically between Jan. 1990 and Sept. 1998 at our hospital were analysed. Variable factors that were examined were : clinical features, effects of treatment, and complications. Results : There were 47 male and 33 female patients. The age at the first presentation was from 3 to 57(mean 34.1) years old. Clinical features were seizure in 28 cases(38%), bleeding in 24 cases(32%), neurologic deficits in 12 cases(16%), headache in 10 cases(14%), and six incidental cases. The locations of lesion were cerebral and cerebellar hemisphere in 45 cases(56.2%), brainstem, basal ganglia, and thalamus in 32 cases(40%), multiple in 3 cases (3.8%). Seizure was common at the third decade and occurred frequently with the cavernous angioma in temporal (43%) or frontal lobe(39%). Bleeding was frequent after the third decade with peak at the fourth decade and had high incidence in brainstem or thalamus. The gamma-knife radiosurgery was done in 47 cases. Rebleeding occurred in 3 cases, but it was within postradiosurgery 1 year. Symptomatic radiation change occurred in 2 cases of 8 radiation change on MRI. On follow-up MRI, no evidence of rebleeding was found in 30 cases. Also, The lesion size was decreased in 3 cases. Resection was performed in 23 cases ; total 20, subtotal 2, partial 1. Postoperative complication occurred in 6 cases(26.1%). After surgery, 7(63.6%) of 11 seizure patients had outcome of seizure-free. Subclinical rebleeding occurred in one of two subtotal resected cases. In 11 patients, conservative management was done. There was neither rebleeding nor symptom aggravation during follow-up period of mean 17.2 months. Conclusion : The solution for prevention of rebleeding is complete removal of the lesion located at noneloquent area or accessible region, especially for the patients who presented symptoms or intractable seizure. However, the Gamma knife radiosurgery is considered when the lesions are located at eloquent area or when severe postoperative morbidity is expected.
Proceedings of the Korean Society of Medical Physics Conference
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2004.11a
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pp.91-95
/
2004
Several MRI studies have reported reductions in temporal lobe volumes in Alzheimer's disease (AD). Measures have been usually obtained with regions-of-interest (ROI) drawn manually on selected medial and lateral portions of the temporal lobes, with variable choices of anatomical borders across different studies. We used the automated voxel-based morphometry (VBM) approach to investigate gray matter abnormalities over the entire extension of the temporal lobe in 10AD patients (MM5E 22)and 22 healthy controls. Foci of significantly reduced gray matter volume in AD patients were detected in both medial and lateral temporal regions, most significantly in the right and left posterior parahippocarmpal gyri. At a more flexible statistical threshold (P<0.01, uncorrected for multiple comparisons), circumscribed foci of significant gray matter reduction were also detected in the right amygdala/enthorinal cortex, the anterior and posterior borders of the superior temporal gyrus bilaterally, and the anterior portion of the left middle temporal gyrus. These VBM results confirm previous findings of temporal lobe atrophic changes in AD, and suggest that these abnormalities may be confined to specific sites within that lobe, rather than showing a widespread distribution.
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