• 한국생물공학회:학술대회논문집
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• 2000.11a
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• pp.147-150
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• 2000

Bioprocess chromatography is probably the most widely used unit operation in biopharmaceutics manufacturing. To obtain a good quality product reproducibly, the chromatography process validation should be performed carefully. We developed a miniaturized automatic chromatography system, MiniValChrom, for column performance validation.

• Journal of Korean Institute of Industrial Engineers
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• v.6 no.1
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• pp.27-38
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• 1980

This paper presents the validation of a stochastic model of muscle fatigue during static muscle contractions. Forty four laboratory experiments, covering eleven test conditions for two trained subjects, were run in order to estimate fatigue and recovery rates, based on EMG observations. The validation of the model was made by comparing the model predictions to the experimental fatigue time. The validation study supports that the stochastic model of muscle fatigue accurately represents the underlying fatigue process. The study also provides support that the fatigue model can be used as a monitor of individual muscle capabilities.

• Communications for Statistical Applications and Methods
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• v.12 no.2
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• pp.413-423
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• 2005

Consider the problem of estimating the underlying regression function from a set of noisy data which is contaminated by a long tailed error distribution. There exist several robust smoothing techniques and these are turned out to be very useful to reduce the influence of outlying observations. However, no matter what kind of robust smoother we use, we should choose the smoothing parameter and relatively less attention has been made for the robust bandwidth selection method. In this paper, we adopt the idea of robust location parameter estimation technique and propose the robust cross validation score functions.

• Journal of the Chungcheong Mathematical Society
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• v.32 no.1
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• pp.149-156
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• 2019

This paper present the global generalized cross validation as the appropriate choice of the regularization parameter in the preconditioned Gl-LSQR method in solving image deblurring problems. The regularization parameter, chosen from the global generalized cross validation, with preconditioned Gl-LSQR method can give better reconstructions of the true image than other parameters considered in this study.

• Journal of Engineering Education Research
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• v.18 no.5
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• pp.3-10
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• 2015

Researchers in science and technology has broadened the scope of research in order to solve complex problems, academic exchange has also been actively carried out. If the paper which is a mean of interdisciplinary approach has a limited term and the formula, it can act as barriers to access for many researchers in various fields. This paper proposes a cross-validation method for eliminating documentary barriers based on discrete event system formalism. We expect that our proposed method will improve a cross-validation considering researchers in another fields.

• YAKHAK HOEJI
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• v.57 no.5
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• pp.362-368
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• 2013

High performance liquid chromatograph (HPLC) is the most frequently used analytical instrument in analytical laboratories for pharmaceutical analysis. In order to provide a high level of assurance for reliable data generated from the HPLC analysis, the performance qualification of the HPLC system is required. For this purpose, the performance of HPLC system should be regularly monitored by examining the key functions of the typical HPLC system (solvent delivery system, injector system, column oven, UV-VIS detector system). We have investigated the validation guidelines of the performance verification of these key modules for HPLC system. And we proposed and evaluated its validation guidelines and the related verification methods for pharmaceutical analysis that could be practically applied in Korea.

• Journal of Internet Computing and Services
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• v.17 no.5
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• pp.43-49
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• 2016

This paper presents a workflow validation method for data-intensive graphical workflow models using real-time workflow tracing mode on data-intensive workflow designer. In order to model and validate workflows, we try to divide as modes have editable mode and tracing mode on data-intensive workflow designer. We could design data-intensive workflow using drag and drop in editable-mode, otherwise we could not design but view and trace workflow model in tracing mode. We would like to focus on tracing-mode for workflow validation, and describe how to use workflow tracing on data-intensive workflow model designer. Especially, it is support data centered operation about control logics and exchange variables on workflow runtime for workflow tracing.

• 한국경영정보학회:학술대회논문집
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• 2007.06a
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• pp.557-561
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• 2007

Along with the significance of information systems in today s global business operation, the significance of information systems control and audit is ever increasing in the effort to secure accuracy and integrity of vital business data. A study is undertaken to integrate Food and Drug Administration computerized systems validation regulations. Securities & Exchange Commission Sarbanes-Oxley Act of 200 and other significant regulations, and lastly, People Capability Maturity Model into one comprehensive information system validation model. The initial benefits to this comprehensive model are convenience, time-saving, and synchronization of the regulations. An organization that is striving for a high level of quality system in its essential operating areas of organization may opt for this model. After the complete development of the model, a field test would be scheduled to test its efficacy and validity.

• Proceedings of the KSRS Conference
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• 2002.10a
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• pp.746-749
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• 2002

This paper is introducing a radio control helicopter as a new platform of ground truth measurement. This helicopter is normally used for spraying an agricultural chemical. It can do pinpoint hovering and programing flight using DGPS etc., A spectrometer with dual port can measure ground surface and white reference plate at the same time. And it can also take digital images by digital camera. It is needed to collect ground reflectance information as satellite sensor footprint size for satellite data validation. Generally it is possible to get such ground reflectance by an airplane measurement. But it is high cost and not so easy to make a measurement by airplane. Developed validation system can provide such ground reflectance in low cost and easy.

• Journal of the Korean Society for Aviation and Aeronautics
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• v.22 no.2
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• pp.81-86
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• 2014

In this paper, we states the verification and validation methodology for the modular system of A-SMGCS which defined in the ICAO Manual on Advanced Surface Movement Guidance and Control Systems. Such systems aim to maintain the declared surface movement rate under all weather conditions while maintaining the required level of safety. With the complete concept of an A-SMGCS, air traffic controllers, vehicle drivers, flight crews, and are assisted with surface operations in terms of surveillance, control, routing/planning and guidance tasks. A-SMGCS verification and validation for the development of Real Time Simulation, shadow mode trials, operational trials are conducted through three methods. In this study, the characteristics and the need for such a verification method was examined.