• 여성건강간호학회지
• /
• 제10권3호
• /
• pp.226-234
• /
• 2004

Purpose: This study was to examine health status, reproductive health problems and the degree of prenatal management in working women. Method: The subjects were 902 married working women among 2,000 women selected by cluster sampling. The work area was classified to product factory, school, office, etc. After an Informed consent was obtained, participants were asked to fill out a self-administered questionnaire. The instruments included a questionnaire, parity check list, menstrual problems and gynecologic problem check list. Result: Many women have experienced menstrual cycle change during the past year. There was a significant difference in general health, menstrual regularity, reproductive health and prenatal management by occupation type. 40.6 percent of the subjects have gynecological problems such as menstrual cycle change, perineal inflammation, irregular vaginal bleeding, amenorrhea, ovarian/uterine disease, infertility, or abortion. Prenatal care was received in only 28.5% of the total subjects. In addition, 16.3% answered they had experienced low birth weight babies. Conclusion: We can conclude that working woman have changes in menstruation cycle and in reproductive health status. Therefore, we suggest that some occupational characteristics may affect subject's reproductive health, these should be clear and avoided as much as possible.

• 한국산학기술학회논문지
• /
• 제19권4호
• /
• pp.403-411
• /
• 2018

본 연구의 목적은 현상학적 접근을 통하여 고강도 초음파 치료를 받은 자궁양성종양 환자에 대한 경험의 본질을 심도 있게 파악하기 위해 이루어졌다. 연구 대상자는 자궁양성종양을 진단받고 고강도 초음파 집속술 치료를 받은 5명의 환자였다. 본 연구의 자료 수집은 2018년 2월부터 3월까지 이루어졌으며, 고강도 초음파 집속술을 시술하고 있는 D시 여성전문병원에서 시행되었다. 연구방법은 일대일 심층 면담을 통해 이루어졌으며, 자료는 비구조적이고 개방된 질문형태를 사용하여 자신의 의견과 경험을 자유롭고 유연하게 표현할 수 있도록 하였다. 인터뷰 자료는 Colaizzi의 현상학적 분석 방법을 사용하였다. 연구결과 5명의 대상자로부터 얻은 고강도 초음파 집속술 치료에 따른 건강문제는 총 3개의 범주로 구성되었고, 각각의 범주는 다시 하부 요인으로 구성되었다. 3개의 범주로는 '불편감', '양가감정', '의지와 요구' 로 나타났다. 본 연구는 고강도 초음파 치료를 받은 자궁양성종양 환자들의 경험을 이해하는데 도움을 줄 것이다. 나아가 본 결과는 향후 여성건강을 위한 새로운 치료법의 개발과 발전에 따라 올바른 간호학적 이해 및 고강도 초음파 치료를 받는 환자에 대한 지속적인 연구와 효과적인 간호 교육프로그램 개발이 이어져야 할 것이다.

• 한국멀티미디어학회논문지
• /
• 제23권7호
• /
• pp.812-818
• /
• 2020

Cervical cancer is the second most common female cancer in the world. In Korea, cervical cancer accounts for 13 percent of female cancers and 4,200 cases occur annually[1]. The purpose of this study is to use a deep learning model to identify the possibility of lesions in the cervix and to evaluate the efficient image preprocessing in order to diagnose diverse types of cervix in form. The study used 4,107 normal photographs of uterine cervix and 6,285 abnormal photographs of uterine cervix. Two types of image preprocessing were resized to square. The methods are cropping based on height and filling the space up and down with black images. In addition, all images were resampled to 256×256. The average accuracy of cropped cases is 94.15%. The average accuracy of the filled cases is 93.41%. According to the study, the model performance of cropped data was slightly better. But there were several images that were not accurately classified. Therefore, the additional experiment with pre-treatment process based on cropping is needed to cover images of the cervix in more detail.

• Journal of Preventive Medicine and Public Health
• /
• 제19권1호
• /
• pp.123-129
• /
• 1986

다태동물의 경태반성독성학실험시 자중내적 요인의 하나로서 자궁내 착상위치가 태자의 출생시 체중에 미치는 영향을 관찰하고, 급 만성 일산화탄소중독으로 저산소상태를 만들었을 때 이러한 외부 요인이 자궁내적 요인에 어떻게 작용하는가를 관찰하고자 백서를 이용하여 정상대조군 및 급 만성 일산화탄소 폭로군에서의 착상부위별 태자의 출생시 체중을 관찰한 바 다음과 같은 소견을 얻었다. 1) 대조군에 있어서는 자궁중앙부에 위치한 태자가 가장 무거운 출생시체중을 나타내었으며 그 다음이 자궁경부, 난소부의 순서였다. 그러나 부위별 체중은 통계적으로 유의한 차이를 보이지 않았다. 2) 급성 CO폭로군에서는 자궁중앙부의 태자체중이 가장 무겁고 자궁경부, 난소부의 순서로 대조군과 양상이 같았으나, 부위별 태자체중의 차이는 통계적으로 유의하였다. 만성 CO 폭로군에서는 자궁중앙부, 난소부, 자궁경부의 순서였으며 자궁부위별 태자체중의 차이는 유의하였다. 이상의 결과를 통하여 정상상태에서는 태자의 자궁내위치는 출생시 체중에 영향을 주지 않으나, 급 만성 CO중독으로 조직저산소증을 일으킨 경우에는 자궁내 착상부위에 따라 태자의 출생시 체중에 영향을 주는 것으로 나타나 다태동물의 출생시 체중을 종속변수로 사용하는 실험연구에서는 태자의 자궁내 착상부위가 교란변수로서 간주되어야 할 것으로 생각된다.

• 대한임상검사과학회지
• /
• 제37권3호
• /
• pp.197-206
• /
• 2005

To determine the correlation between mast cells(MCs) and neoangiogenesis in the growth and progression of cervical cancer, we investigated mast cell density(MCD), microvessel density(MVD) and the expression of vascular epithelial growth factor(VEGF) in cervical intraepithelial neoplasia and invasive suqamous cell carcinoma of the uterine cervix. Forty-five cervical intraepithelial neoplasia(CIN I, II and III), 15 microinvasive carcinomas, 15 invasive squamous cell carcinomas and 20 normal cervical epithelia were included in this study. MCs were stained with anti-c-Kit antibody and alcian blue, microvessels with anti-factor VIII antibody and VEGF with anti-VEGF antibody. The adjacent fields of both normal and neoplastic epithelium were used for counting MCs and microvessels. Computerized image analysis was used to evaluate MCD and MVD. MCD and MVD were the mean numbers per $1mm^2$ counted in 5-10 high and low power fields respectively. In both c-Kit and alcian blue stained sections, MCD progressively increased along the continuum from CIN I to invasive squamous cell carcinoma(p<0.001). MVD increased significantly with cervical neoplasia progression, from CIN to invasive squamous cell carcinoma (p<0.001). In double c-Kit and Factor VIII-stained sections, MCs were mainly present in the areas adjacent to newly formed blood vessels. However, there were no significant differences in MCD and MVD between normal epithelum and CIN I. A strong correlation was also observed between MCD and MVD. In double VEGF and alcian blue-stained sections, VEGF was expressed in only MCs. Strong VEGF-positive MCs were particularly abundant around the tumorous region. Our results suggest that MCs may upregulate neoangiogenesis by VGEF secretion in the development and progression of cervical neoplasia.

• Asian Pacific Journal of Cancer Prevention
• /
• 제15권16호
• /
• pp.6749-6754
• /
• 2014

Background: There are limited data in the literature related to concomitant genital or extra-genital organ pathologies in patients with borderline ovarian tumors (BOTs). The aim of this study was to evaluate our experience with 183 patients to draw attention to the accompanying organ pathologies with BOTs. Materials and Methods: One hundred eighty-three patients with BOTs, diagnosed and/or treated in our center between January of 2000 and March of 2013 were evaluated retrospectively. Data related to age, tumor histology, lesion side, disease stage, accompanying incidental ipsilateral and/or contralateral ovarian pathologies, treatment approaches, and follow-up periods were investigated. Incidental gynecologic and non-gynecologic concomitant organ pathologies were also recorded. Results: The mean age at diagnosis was 40.6 years (range: 17-78). Ninety-five patients (51%) were ${\leq}40$ years. A hundred and forty-seven patients (80%) were at stage IA of the disease. The most common type of BOT was serous in histology. Non-invasive tumor implants were diagnosed in 4% and uterine involvement was found 2% among patients who underwent hysterectomies. There were 12 patients with positive peritoneal washings. Only 17 and 84 patients respectively had concomitant ipsilateral and concomitant contralateral incidental ovarian pathologies. The most common type of uterine, appendicular and omental pathologies were chronic cervicitis, lymphoid hyperplasia and chronic inflammatory reaction. Conclusions: According to our findings most of accompanying pathologies for BOT are benign in nature. Nevertheless, there were additional malignant diseases necessitating further therapy. We emphasize the importance of the evaluation of all abdominal organs during surgery.

• 한국동물위생학회지
• /
• 제30권3호
• /
• pp.429-436
• /
• 2007

This study was performed to make helpful standard for discrimination of cows from heifers by uterine and ovarian section inspection. A total of 3,736 heifers and 249 cows were inspected from January to November 2006 in Karak Market Slaughter house. Firstly, it was obvious that non-corpus albicans were observed in almost heifers(3,597/3,736, 96.3%), but there were distinctive corpus albicans in all cows (249/249 100%). Secondly, another evident was that the length and diameter of the horn in uterus was below 30mm in 94.5% (3,267/3,736) heifers, but above 30mm in 90.4% (225/245) cows, and it was easy to distinguish between right and left horn by difference of size in 87.6% (218/249) cows. Thirdly the diameters of pelvic cavity was below 220mm in 96.8% (3,615/3,736) heifers, but was over 200mm in 85.1% (212/249) cows. Fourthly another difference was found in second sacrum union condition and 13th thoracic vertebral process's states. In case of heifers, it was distinctive five lines in each second sacrum, but it was non-distinctive or united in the same each lines of the sacrum in cows. Fifthly in the results of 13th thoracic vertebral colors, the ratio between red color and white color was 7 : 3 in heifers (3,385/3,736, 90.6%), but that was 2 : 8 in cows (199/249, 79.9%). Consequently, it was possible to use the method which discriminated cows from heifers by uterine and ovarian section inspection in large scaled field slaughter house.

• 한국발생생물학회지:발생과생식
• /
• 제24권1호
• /
• pp.1-17
• /
• 2020

Phthalates and those metabolites have long history in industry and suspected to have deficient effects in development and reproduction. These are well-known anti-androgenic chemicals and many studies have examined the effects of these compounds on male reproduction as toxins and endocrine disruptors. Uterus is a key organ for proper embryo development, successful reproduction, and health of eutherian mammals including women. To understand the effects of the phthalate, the horizontal approach with a whole group of phthalate is best but the known phthalates are huge and all is not uncovered. Di-(2-ethylhexyl) phthalate (DEHP) is the most common product of plasticizers in polymer products and studied many groups. Although, there is limited studies on the effects of phthalates on the female, a few studies have proved the endocrine disrupting characters of DEHP or phthalate mixture in female. An acute and high dose of DEHP has adverse effects on uterine histological characters. Recently, it has been revealed that a chronical low-dose exposing of DEHP works as endocrine disrupting chemicals (EDC). DEHP can induce various cellular responses including the expression regulation of steroid hormone receptors, transcription factors, and paracrine factors. Interestingly, the response of uterus to DEHP is not monotonous and the exposed female has various phenotypes in fertility. These suggest that the exposing of DEHP may causes of histological modification in uterus and of disease in female such as endometriosis, hyperplasia, and myoma in addition to developmental and reproductive toxicity.

• 한국임상수의학회지
• /
• 제19권4호
• /
• pp.426-428
• /
• 2002

유산후 반복적인 자궁내 항생물질 주입의 병력이 있는 7세의 말이 자궁내막염을 나타내었다. 이 말은 자궁경관 점막의 충혈과 부종을 보였고, 회백색의 화농성 삼출액이 배설되었다. Candida albicans가 원인균으로 증명되었으며 이 진단은 자궁 삼출액의 직접 현미경 검사와 순수 배양물의 검사에 의해 증명하였다. 실험실적 디스크 확산실험에서 병원체가 amphotericin B, clotrimazole, fluconazole 및 nystatin 등 네 가지의 항진균제에 모두 감수성을 나타내었다. 4일간 nystatin 400,000 단위씩을 자궁내 주입하였더니 성공적으로 치유되었으며, 마지막 주입 후7일에 직접도말 검사와 배양에서 병원체가 다시 발견되지 않았다.

• Journal of Korean Biological Nursing Science
• /
• 제17권2호
• /
• pp.211-217
• /
• 2015

Purpose: The purpose of this study is to identify factors influencing the pregnancy rate among unexplained infertile couples who received treatments of assisted reproductive technology (ART) and intra-uterine inseminations (IUI). Methods: The medical records of 24,201 cases of unexplained infertility among a total of 31,684 intrauterine insemination treatment cases, (which benefited by 'National Medical-aid Program for ART in 2011') were used for this analysis. Results: Woman's age (OR=0.94), frequency of IUI (OR=0.86), and treatment type (OR=1.54) were significant factors on pregnancy rates in the logistic regression analysis. Conclusion: Factors, such as the age of the infertile woman, frequency of IUI, and treatment type used to induce ovulation were shown to positively influence pregnancy rate. However, the age of the spouse was not a significant variable. Infertile couples having unprotected sexual intercourse with unexplained infertility had priority. The results demonstrated that about 70% of infertile Korean couples had unexplained infertility. This was a higher rate of unexplained infertility than that of the clinical standard. Therefore, we should assess for causes through future studies. In addition, affective or emotional factors influencing unexplained infertility need to be researched further.