• Journal of Microbiology and Biotechnology
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• v.23 no.11
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• pp.1544-1553
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• 2013

Despite the importance of acetate kinase in the metabolism of bacteria, limited structural studies have been carried out on this enzyme. In this study, a three-dimensional structure of the Escherichia coli acetate kinase was constructed by use of molecular modeling methods. In the next stage, by considering the structure of the catalytic intermediate, trifluoroethanol (TFE) and trifluoroethyl butyrate were proposed as potential inhibitors of the enzyme. The putative binding mode of these compounds was studied with the use of a docking program, which revealed that they can fit well into the enzyme. To study the role of these potential enzyme inhibitors in the metabolic pathway of E. coli, their effects on the growth of this bacterium were studied. The results showed that growth was considerably reduced in the presence of these inhibitors. Changes in the profile of the metabolic products were studied by proton nuclear magnetic resonance spectroscopy. Remarkable changes were observed in the quantity of acetate, but other products were less altered. In this study, inhibition of growth by the two inhibitors as reflected by a change in the metabolism of E. coli suggests the potential use of these compounds (particularly TFE) as bacteriostatic agents.

• Journal of Pharmacopuncture
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• v.26 no.1
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• pp.1-9
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• 2023

Objectives: Polycystic ovary syndrome (PCOS) is a condition that occurs frequently among women of reproductive age and is a polygenic, multifactorial, endocrine, and metabolic disorder. PCOS is becoming more common as a result of risk factors such as current lifestyle, overnutrition, and stress. The use of traditional herbal medicine is higher among the global population. Hence, this review article focuses on the potential of Nigella sativa to manage women with PCOS. Methods: A literature search was carried out using databases including Medline, Google Scholar, EBSCO, Embase, and Science Direct, as well as reference lists, to identify relevant publications that support the use of N. sativa in the management of women with PCOS. Results: Several clinical and preclinical studies have demonstrated that the major bioactive constituent of black seed (N. sativa), thymoquinone, has potential for managing women with PCOS. Moreover, N. sativa may help to manage oligomenorrhea and amenorrhea in women with PCOS through its anti-inflammatory and antioxidant properties. Conclusion: N. sativa has potential for use as a herbal medicine for managing women with PCOS as an integrative medicine along with traditional and modern medicine in conjunction with calorie restriction and regular exercise.

• International conference on construction engineering and project management
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• 2020.12a
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• pp.291-300
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• 2020

Newly graduated students are shown to constitute an important source of innovation within the architectural, engineering and construction (AEC) industry. In relation to digital technologies like BIM (Building Information Modelling) that is claimed to have a potential to transform the industry, newly graduated students may play a vital role in innovating with BIM. The paper aims to explore determinants for students perceived potential of BIM use (PPBU) and the role of the educational background. The aim will be achieved by analysing the results from a survey conducted among third- and fourth-year students in construction and civil engineering in Hong Kong, Sweden, and Thailand (n = 194). When the different groups are compared Swedish and Thai students perceive a significant higher PPBU than Hong Kong students. In a step-wise multiple regression analysis five predictors for PPBU were identified for Thai respectively Swedish students, and one predictor was identified for Hong Kong students. It is concluded that in the contemporary BIM-discourse it is claimed that BIM can/should transform the industry, and BIM is even seen as a disruptive technology, and newly graduated students will contribute to (digitally driven) innovation. However, from the predictors of PPBU, the question can raised if the awareness of the need for structural changes is lacking in the education, if students later in their working life should contribute to a BIM-induced transformation of the industry?

• The Journal of Information Systems
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• v.32 no.3
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• pp.225-251
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• 2023

Purpose The purpose of this study is to examine the future direction of in-vehicle app development and service, the relationship between potential customers' intention to use and the factors that affect it was explored. It was also checked whether the two types of app development platform and the experience of the existing smartphone app platform had a moderating effect on these relationships. Design/methodology/approach Data was gathered through surveys, collecting responses from 904 potential consumers of vehicle app services in Korea. Structural equation modeling was utilized to analyze the data. Findings According to the empirical analysis result, it was found that potential customers considered enjoyment as the most important benefit factor in in-vehicle app service, and the most important external factor affecting enjoyment was functional compatibility with smartphone. The type of vehicle app development platform did not have a meaningful moderating effect on the factor relationship, whereas the smartphone app platform experience showed a meaningful moderating effect on the relationship between factors. It was analyzed that the risk of app performance, personal information privacy, and driving safety data did not have a negative effect on the intention to use the vehicle app service.

• Journal of Korean Society for Atmospheric Environment
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• v.11 no.E
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• pp.13-21
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• 1995

This Pilot study identifies potential dioxin and furan sources and medical plastic wastes produced from hospital solid waste streams. In this study, air emissions of dioxins and furans from sources in the U.S., which were estimated by the U.S. Environmental Protection Agency (EPA), were summarized. Potential loading routes of dioxins and furans to the U.S.-Canada Great Lakes region have also been identified in trcent surveys. In addition, medical and hospital solid wastes produced in typical large city hospitals were characterized as important potential sources of dioxins and furans. Plastic contents in medical Plastics Characterization Survey (MMPCS), plastics composition data were obtained from a survey of five Massachusetts Hospitals and Medical Centers. By identifying plastic wastes as a percentage of total hospital wastes, we were able to use data from a preliminary study that analyzed the waste stream of 16 major New York City hospitals (NYCMWS) characterizing the plastic content of the wasters. This study determined the types of plastic wastes included in each medical waste stream (regulated medical waste or non regulated medical waste) and it discussed the potential for recyclibility of hospital plastic wastes. The combination of the NYCMWS and the MMPCS surveys provides for the first overview of the size of the recycling task of hospital plastic wastes and the potential of dioxin elimination if dioxin generating plastics were to be eliminated from hospital use.

• KCID journal
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• v.17 no.2
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• pp.82-94
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• 2010

Recently, biomass application for energy is getting more interests from many countries since biomass is widely available over the nation wide, whereas fossil fuels are produced in several limited regions. Recognizing the importance, government is promoting renewable energy use in Korea. The locational characteristics of the existing biomass potential directly can be used to decide scale of power plant for local agricultural facility. Although there are a few studies on feasible biomass potential in local areas, it is expected that both government and commercial sectors recognize the potential of biomass energy and the importance of reducing greenhouse gases. When planning biomass energy systems, biomass price is determined by the costs of collection, transportation, chipping, drying if required. In this paper investigates the economic and spatial characteristic of biomass location by land use map. However typical area of each categories in local region is not correct to agricultural census data. Therefore we concerned about how to calculate feasible biomass potential which it can be describing total amount of plant scale, and to match both of data. Even though its spatial distribution, in rural area in Korea, to expand biomass energy programs in the area, government serve to find areas of higher biomass production with suitable locations for plants to convert to bio-energy in order to increase the usage of renewable energy.

• Journal of Distribution Science
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• v.21 no.5
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• pp.93-102
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• 2023

Purpose: This study aims to investigate a meaningful connection between the service supply chain and the power to influence potential customers for airline booking. This investigation will cover various topics, including customer service, product quality, and marketing strategies. Additionally, the literature review will examine the various strategies and tactics airlines use to influence customer behavior. Research design, data, and methodology: The data collection process conducted by the author could obtain the justification and establish the quality of the instrument between independent factor (Service Supply Chain) and dependent factor (Power to Influence Potential Customers), selecting peer-reviewed articles mostly for the current study. Results: The findings section thoroughly studied the research findings indicating a potential link between service supply chain management and the ability to persuade potential consumers to book an airline. The research findings will be explored concerning the numerous variables that may affect customers' decision-making in the airline business, the techniques used by airlines to sway consumers. Conclusions: The research has provided evidence that airlines use a variety of strategies to influence potential customers and that these strategies are generally successful in increasing customer loyalty and satisfaction, as well as sales. By utilizing these strategies, airlines can increase their customer base and profitability.

• Korean Chemical Engineering Research
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• v.53 no.6
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• pp.831-835
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• 2015

This study evaluated the influence of the zeta potential of silica-alumina on the behavior in terms of purity, yield, and precipitate shape and size of fractional precipitation in the fractional precipitation process for the purification of (+)-dihydromyricetin. The optimal silica-alumina amount (surface area per working volume of reacting solution) for zeta potential control was $100mm^{-1}$. As the zeta potential value of silica-alumina increased, (+)-dihydromyricetin yield and precipitate size were increased. The use of silica with the highest value of the zeta potential (+4.99 mV) as a zeta potential-controlling material increased the (+)-dihydromyricetin yield by 2-fold compared with that of the use of alumina with the lowest value of the zeta potential (-19.00 mV). In addition, the (+)-dihydromyricetin yield and precipitate size was inversely correlated with the absolute value of the zeta potential. On the other hand, the purity of (+)-dihydromyricetin had almost no effect on changes in the zeta potential of silica-alumina.

• Korean Journal of Clinical Pharmacy
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• v.24 no.1
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• pp.53-61
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• 2014

Background: The use of health functional food (HFF) is increasing and will continue to rise worldwide. Concerns about HFF-drug interactions are increasing as HFF are becoming more widely used. Therefore, awareness of consumers' perceptions and behaviors associated with HFF use may help health care providers improve their communications with patients. Purpose: The aim of this study was to assess the characteristics, perceptions, and behaviors associated with HFF use in South Korea. Method: The online survey was conducted from September 21th to October 7th, 2013. With the aid of Social Network Service (SNS) and google, the questionnaire was posted online on internet website targeting people aged 15 years or older so that self-reported data covering 4 domains were collected from 257 Koreans. Results: A total of 257 people responded the questionnaire. Among them, 81.3% reported experiences of HFF use. Female were more likely than male to use HFFs. There were no differences in demographic characteristics between HFF users and non-users in relation to age, education, and household income. Higher level of education was associated with high-level perception of HFF function (OR 3.9, 95% CI 1.48, 10.1) and a positive relationship was observed between the maximum number of HFFs used concurrently and age of the respondents. Among the HFF users, 42.6% reported concurrent HFF-medication use. However 73.3% of them did not disclose their use to physician or pharmacist and only 30.2% were informed about potential drug-HFF interactions. Pharmacy was most commonly reported as the source from which the respondents were informed about potential interactions. Conclusion: Many people had used HFF and medications concurrently while not being informed about potential HFF-drug interactions. Pharmacists and physicians should be vigilant for risk of the interactions and actively determine whether the patient is using an HFF before prescribing and administrating medications.

• Journal of Energy Engineering
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• v.11 no.1
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• pp.34-46
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• 2002

Carbon accounting is a key issue in the discussions on global warming/CO$_2$mitigation. This paper applies both the IPCC Approach and the NEAT (Non-Energy use Emission Accounting Tables) model, a bottom-up approach, to estimate the potential CO$_2$ emissions (carbon storage) originating from the non-energy use as to assess the actual CO$_2$ emissions (carbon release) from the use of fossil fuels in Korea. The current Korean carbon accounting seems to overestimate the potential CO$_2$ emissions and with it to underestimate the actual CO$_2$ emissions. The estimation shows that the potential CO$_2$ emissions calculated according to the IPCC Approach are lower than those calculated using the NEAT model. This is because the IPCC default storage fraction for naphtha seems to be low for the Korean petrochemical production structure, on the one hand and because the IPCC Approach does not consider the trade with short life petrochemical products, on the other hand. This paper shows that a bottom-up approach like the NEAT model can contribute to overcome some of limitations of the IPCC guidelines, especially by considering the international trade with short life petrochemical products and by estimating the storage fractions of fossil fuels used as feedstocks for the country in consideration. This paper emphasizes the importance of accurate energy statistics for carbon accounting.