• Natural Product Sciences
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• v.10 no.6
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• pp.253-261
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• 2004

Ten terpenes (1-10), two sterols (11 and 12), and two unusual phenylpropanoids (13 and 14) were isolated from the brittle star Ophioplocus japonicus (Family Ophiuridae). Their structures were identified by analyses of the spectral data and by comparison with the literature data. The terpenes (1-10) and phenylpropanoids (13 and 14) are first encountered in brittle stars. These compounds were evaluated for cytotoxicity against a small panel of human solid tumor cell lines. Compounds 6-10 and 14 displayed moderate to significant cytotoxicity. The compounds were evaluated for antibacterial activity against 20 clinically isolated strains. Compound 5 exhibited antibacterial activities against three Streptococcus and three Staphylococcus strains.

• Journal of the Korean Magnetic Resonance Society
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• v.11 no.2
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• pp.122-128
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• 2007

Three sterol sulfates were isolated from AMPK activity-guided fraction of a marine sponge Acanthodoryx fibrosa. Their structures were determined by an extensive NMR analysis, MS data, and two compounds were confirmed as unusual phosphorylated sterol sulfates by comparing with NMR data of the known compounds. Compound 3 was given to be a new dephosphated sterol sulfate derivative. Compound 1 moderately showed AMPK activation effect on L6 myoblast cell through Western blot analysis.

• Biotechnology and Bioprocess Engineering:BBE
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• v.9 no.5
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• pp.414-418
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• 2004

A 'minimally complex problem set' for ab initio protein Structure prediction has been proposed. As well as consisting of non-redundant and crystallographically determined high-resolution protein structures, without disulphide bonds, modified residues, unusual connectivities and heteromolecules, it is more importantly a collection of protein structures. with a high probability of being the same in the crystal form as in solution. To our knowledge, this is the first attempt at this kind of dataset. Considering the lattice constraint in crystals, and the possible flexibility in solution of crystallographically determined protein structures, our dataset is thought to be the safest starting points for an ab initio protein structure prediction study.

• Proceedings of the Korean Geotechical Society Conference
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• 2009.03a
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• pp.1020-1025
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• 2009

Recently, unusual change of weather occurred in world wide region causes localized heavy rainfall and consequently disasters like landslide and debris flow in steep slope area. And the main factors of these disasters are rainfall and forest fire. To verify the existing landslide prediction and warning system, information about landslide and rainfall were collected for a data base system and analysed.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.22 no.51
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• pp.1-10
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• 1999

In recent industry society, it is revealed that, as an increase in the use of automated manufacturing and process inspection technology, the data from mass production system exhibits some degrees of autocorrelation. The operation characteristics of traditional control charts developed under the independence assumption are adversely affected by the presence of serial correlation. Therefore, when autocorrelated construction contacted with time-series models explain, the time-series models are the Box-Jenkins forecast models which have been proposed as the best forecasting tool which allows for partitioning of variation into result from the autocorrelation structure and variation due to unusual but assignable causes. In this paper, for the AR(1) process of Box-Jenkins forecast models, when the constant term ξ are zero and different from zero, I want to analyze the sensitivity of (equation omitted), CUSUM and EWMA control chart for forecast residuals.

• Proceedings of the KSR Conference
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• 2009.05a
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• pp.148-151
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• 2009

In these days it is important to secure the life and stability of the structure such as aircrafts, automobiles and building. So the structural health monitoring is needed. In conventional lamb wave techniques, damage is identified by comparing the measured data (baseline signals) and the current data. But this method can lead to high false signal in the intact condition of the structure due to environmental conditions of the structure. As a solution to resolve it, the structural health monitoring method which doesn't use baseline signals is necessary. Damaged structure has unusual elastic wave. This paper proposed a PC(pitch-catch) method which doesn't use baseline signal. New baseline signals can get from detection signal. Damage signals based on new baseline signals. This paper made an image includes damage information by applying damage-signals to beamformming.

• The Transactions of the Korea Information Processing Society
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• v.6 no.6
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• pp.1571-1580
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• 1999

When a hierarchical structure is derived from data set for data mining and machine learning, using a conceptual clustering algorithm, one of the unsupervised learning paradigms, it is not unusual to have a different set of outcomes with respect to the order of processing data objects. To overcome this problem, the first classification process is proceeded to construct an initial partition. The partition is expected to imply the possible range in the number of final classes. We apply center sorting to the data objects in the classes of the partition for new data ordering and build a new partition using ITERATE clustering procedure. We developed an algorithm, REIT that leads to the final partition with stable and best partition score. A number of experiments were performed to show the minimization of order bias effects using the algorithm.

• Journal of Korean Medical classics
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• v.32 no.1
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• pp.61-74
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• 2019

Objectives : The purpose of this study is to help select an appropriate word embedding method when analyzing East Asian traditional medicine texts as data. Methods : Based on prescription data that imply traditional methods in traditional East Asian medicine, we have examined 4 count-based word embedding and 2 prediction-based word embedding methods. In order to intuitively compare these word embedding methods, we proposed a "prescription generating game" and compared its results with those from the application of the 6 methods. Results : When the adjacent vectors are extracted, the count-based word embedding method derives the main herbs that are frequently used in conjunction with each other. On the other hand, in the prediction-based word embedding method, the synonyms of the herbs were derived. Conclusions : Counting based word embedding methods seems to be more effective than prediction-based word embedding methods in analyzing the use of domesticated herbs. Among count-based word embedding methods, the TF-vector method tends to exaggerate the frequency effect, and hence the TF-IDF vector or co-word vector may be a more reasonable choice. Also, the t-score vector may be recommended in search for unusual information that could not be found in frequency. On the other hand, prediction-based embedding seems to be effective when deriving the bases of similar meanings in context.

• The Korean Journal of Quaternary Research
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• v.17 no.2
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• pp.55-61
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• 2003

In the year 2000 we culminated a successful five year investigation of climate change by completing a preliminary east-west transect across Mongolia. An earlier tree-ring study at Tarvagatay Pass, Mongolia indicated unusual warming during the 20th century similar to other paleo-investigations of the northern hemisphere. This record had represented one of the few tree-ring records for central Asia. New data from several sites in western Mongolia confirmed the preliminary temperature. The highest twenty-year growth period for the composite record is from 1973-1994. The western Mongolian record was significantly correlated with the Taimyr Peninsula and two northern hemisphere temperature reconstructions reflecting large-scale temperature patterns while showing some important regional differences. These differences should prove useful for climate models. We have also developed a millennial length temperature-sensitive record at the Solongotyin Davaa site (formerly Tarvagatay Pass) using relict wood and living trees. Conspicuous features over the last 1000 years are a century scale temperature decline punctuated by the end of the Little Ice Age in the late-1800s and 20th century warming. The record also shows a cold period early in the 12th century and warm intervals late in the 10th, early in the 15th and at end of the 18th centuries. Despite a limited sample size before 900 AD, the long Solongotyin Davaa record is useful in indicating severe cold events and suggests some cold intervals nearly as severe. These tree ring series, spanning much of the circumpolar northern treeline, have been compiled to create a long-term reconstruction of the Earth's temperature over centuries. The new chronology, in addition to its value as a detailed record of Mongolian climate, provides independent corroboration for such hemispheric and global reconstructions and their indications of unusual warming during the 20th century.

• Journal of the Korean Institute of Landscape Architecture
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• v.30 no.2
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• pp.12-22
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• 2002

This study examines the visitors'evaluations of tourism resources in Insa-dong, which the Seoul metropolitan government has improved recently. This study adopted the method of Importance-Performance Analysis by collecting data through questionnaires. A random sampling of visitors to Insa-dong was conducted in June and July,2001. The survey included questions on the physical and psychological components of Insa-dong's tourism resources. In the case of physical components, eight factors(ancient arts shop, art gallery, atelier, calligraphy shop, pottery arts, traditional tea house, antique shop, traditional clothes) out of thirteen were categorized as 'keeping up the good work'. None of the Physical components was shown as 'low priority'or'possible overkill'. In particular, four factors(restaurant, heritage, Korean-style house and alley, traditional cultural festival) need to be impoved most urgently in terms of visitors'satisfaction. Survey results realize them as high priority in importance but low in performance, thereby designated as, 'concentrate here'. An image of the 'street' showed to be high in importance and identical in performance, so can be categorized between'keeping up the good work'and 'concentrate here'. The results show that unusual outdoor spaces and the festivals of Insa-dong have a significant meaning to the visitors. In the case of psychological components, three factors(general atmosphere experience of unusual atmosphere, appropriateness of stroll time) out of seventeen were categorized as 'keeping up the good work'. Ore factor (shopping) was designated as 'low priority'and not found to be 'possible overkill'. Thirteen factors (various events, possibility of various activity, various flood, richness of play, new experience, education cultural inheritance, parking facilities, resting places, green spaces, meeting places, guide map and information, cleanliness of facilities/convenience) need to be improved mast urgently in terms of visitors' fulfillment. They are perceived as areas of 'concentrate here'. This confirms that attractive events are essential for the recent visitor satisfaction. Furthermore, visitors are not satisfied with its amenity and acccss in Insa-dong despite the improvements. In conclusion, positive impressions, both physical and psychological, should be maintained while factors mentioned to be lacking should be prioritized in order of necessity to improve the image of Insa-dong and solutions need to be found and implemented. The results of this study would be helpful in the planning and management of nsa-dong considering the visitors'requirements.