Journal of the Korean Magnetic Resonance Society (한국자기공명학회논문지)

Korean Magnetic Resonance Society (한국자기공명학회)
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Three Sterol Sulfates Isolated from a Marine Sponge Acanthodoryx Fibrosa

  • Park, Su-Young (Department of Oceanography, Kunsan National University) ;
  • Hwang, Byung-Su (Department of Oceanography, Kunsan National University) ;
  • Ji, Kwang-Hee (Department of Oceanography, Kunsan National University) ;
  • Rho, Jung-Rae (Department of Oceanography, Kunsan National University)
  • Published : 2007.12.20
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Abstract

Three sterol sulfates were isolated from AMPK activity-guided fraction of a marine sponge Acanthodoryx fibrosa. Their structures were determined by an extensive NMR analysis, MS data, and two compounds were confirmed as unusual phosphorylated sterol sulfates by comparing with NMR data of the known compounds. Compound 3 was given to be a new dephosphated sterol sulfate derivative. Compound 1 moderately showed AMPK activation effect on L6 myoblast cell through Western blot analysis.

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