• Journal of Korean Critical Care Nursing
• /
• v.4 no.2
• /
• pp.27-38
• /
• 2011

Purpose: The purpose of this study was to examine the effect of tooth-brushing oral care on oral health and ventilator-associated pneumonia of patients in Intensive Care Unit (ICU). Methods: A total of 74 participants were recruited from a medical, surgical, or neurosurgical ICU at S Hospital in Seoul, Korea, from September of 2010 to January of 2011. An experimental group (n= 36) received oral care with tooth-brushing while a control group (n=38) received oral care with cotton ball and gauze. In both group, the oral care was done three times a day at least one minute for 7 days. Oral health was examined by the Modified Oral Assessment Guide before the intervention and each night. Results: There is no difference between the groups in aspect of passage of time (p = .603), interaction between time and intervention (p =.300), the performance intervention (p = .766), and the incidence of VAP (p = .486). Conclusion: The effect of oral care with tooth-brushing on oral health and VAP was not different from that of usual oral care in ICU. However, further study is necessary due to high attrition in this study.

• Journal of Microbiology and Biotechnology
• /
• v.32 no.4
• /
• pp.531-540
• /
• 2022

Due to the high incidence of malignant melanoma, the establishment of in vitro models that recapitulate the tumor microenvironment is of great biological and clinical importance for tumor treatment and drug research. In this study, 3D printing technology was used to prepare GelMA/PEGDA composite scaffolds that mimic the microenvironment of human malignant melanoma cell (A375) growth and construct in vitro melanoma micro-models. The GelMA/PEGDA hybrid scaffold was tested by the mechanical property, cell live/dead assay, cell proliferation assay, cytoskeleton staining and drug loading assay. The growth of tumor cells in two- and three-dimensional culture systems and the anti-cancer effect of luteolin were evaluated using the live/dead staining method and the Cell Counting Kit-8 (CCK-8) method. The results showed a high aggregation of tumor cells on the 3D scaffold, which was suitable for long-term culture. Cytoskeleton staining and immunofluorescent protein staining were used to evaluate the degree of differentiation of tumor cells under 2D and 3D culture systems. The results indicated that 3D bioprinted scaffolds were more suitable for tumor cell expansion and differentiation, and the tumor cells were more aggressive. In addition, luteolin was time- and dose-dependent on tumor cells, and tumor cells in the 3D culture system were more resistant to the drug.

• 한국생물공학회:학술대회논문집
• /
• 2003.10a
• /
• pp.683-686
• /
• 2003

While genetically modified organisms (GMOs) are producing in many countries, issues related to safeties of GMOs as foods for human have risen. Because of such potential problems, the development of an indication system regarding GMO content contained in foods has been required. Particularly, an immune-chip, as widely demanded diagnostic tool for functional, structural analyses of proteins, has been investigated to simultaneously measure different analytes. We have developed methods for immobilizing antibody on glass surfaces as substrate and for generating chemiluminometric signals.

• Proceedings of the Korean Society for Bioinformatics Conference
• /
• 2005.09a
• /
• pp.383-387
• /
• 2005

One of the most important issues in post-genome era is identifying functions of genes and understanding the interaction among them. Such interactions from complex biochemical pathways, which are very useful to understand the organism system. We present an integrated biochemical pathway database system with a set of software tools for reconstruction, visualization, and simulation of the pathways from the database. The novel features of the presented system include: (a) automatic integration of the heterogeneous biochemical pathway databases, (b) gene ontology for high quality of database in the integration and query (c) various biochemical simulations on the pathway database, (d) dynamic pathway reconstruction for the gene list or sequence data, (e) graphical tools which enable users to view the reconstructed pathways in a dynamic form, (f) importing/exporting SBML documents, a data exchange standard for systems biology.

• Communications for Statistical Applications and Methods
• /
• v.8 no.2
• /
• pp.507-514
• /
• 2001

In recent years, the development and the embodiment of information analysis system has been sprightly carried out in several fields of study. In this study, as and extension of these studies, we develop a system for multivariate analysis which might be widely used in social and natural sciences. This multivariate analysis system is developed by using multivariate analysis procedures in SAS/STAT software. Also, the system supply users with he environment of GUI(Graphical User Interface), which is constructed with AF(application frame) and SCL(screen control language) of SAS software, in order to help users to use the system with easy.

• Journal of Electrical Engineering and Technology
• /
• v.8 no.5
• /
• pp.1212-1220
• /
• 2013

In general, for a large power system like DC distribution system for buildings, several power converters are modularized for parallel operation. However, in parallel operation, inconsistency of parameters in each module causes circulating current in the whole system. Circulating current is directly related to loss, and, therefore, it is most important for the safety of the power system to supply the suitable current to each module. This paper proposes a control method to reduce circulating current caused during parallel operation. Accordingly, the validity of parallel operation system including response characteristics and normal state was verified by simulation and experiment result.

• Proceedings of the KIEE Conference
• /
• 2005.07d
• /
• pp.2843-2845
• /
• 2005

This paper deals with the design of real-time embedded system using RTOS (real-time operating system) and SOPC (system on a programmable chip). It is, in general, known that RTOS has the problem of time delay caused by the multiple tasks and task management approach. Since the increase in time delay in real-time embedded system makes the overall system have the poor performance or the critical behavior of instability and unreliability, the method employed RTOS and SOPC is proposed to attack the above problems. The proposed system is implemented on the RC-motor controller and is verified by real experiment.

• Proceedings of the KIEE Conference
• /
• 2002.07a
• /
• pp.533-535
• /
• 2002

In Korea, power requirement has been increasing. But the large generation unit is hardly installed because of economic and environment problem. Therefore, the concern of dispersed generation system(DGS) is growing. The power distribution system is generally operated with radial type. The protection system is composed of one directive source. But power distribution system inserted DGS changes it to two directive source system. Therefore, the insertion of DGS has the problem of protection coordination. In this paper, we argue fault current affected by interconnected DGS. We analyze fault current flow affected by DGS placement. Then, we find protective coordination problem. Consequently, we study advance point for protection scheme of power system interconnected DGS.

• Proceedings of the IEEK Conference
• /
• 2008.06a
• /
• pp.1199-1200
• /
• 2008

In this paper, we suggest a system architecture for korean air traffic control system through investigating a korean ARTS (Automated radar terminal system) and ACC (Area control center) system. We focus on designing a network architecture for supporting both an approaching control and an area control. This paper will be a base for developing korean air traffic control system by ourselves.

• Proceedings of the KIPE Conference
• /
• 2005.07a
• /
• pp.523-525
• /
• 2005

In this paper, electronic-controlled power supply(EPS) system for solar cell characteristic is proposed to solve various problems and to achieve reliable experimental result on photovoltaic system. This system emulates the solar cell output characteristics, and it can substitute solar cell in laboratory experiment system. New model for solar cell is proposed to realize the EPS system for solar cell, which is based on the interpolation. Both simulation and experiment are executed to show the validity of the proposed EPS system.