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Effectiveness of Microsatellite Markers for Parentage Analysis of Giant Grouper (Epinephelus lanceolatus) Broodstock (Microsatellite 마커를 이용한 대왕바리(Epinephelus lanceolatus) 친어 집단의 가계도 분석 효율)

  • Kim, Keun-Sik;Noh, Choong Hwan;Sade, Ahemad;Bang, In-Chul
    • Korean Journal of Ichthyology
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    • v.27 no.1
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    • pp.10-15
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    • 2015
  • Giant grouper (Epinephelus lanceolatus) is a endangered species considered as a vulnerable grade-organism in the International Union for Conservation of Nature (IUCN) red list. As a fundamental baseline study for establishing a giant grouper broodstock management system, the efficiency for parentage analysis was evaluated by using microsatellite makers previously available in this species. The eight microsatellites generated a total 52 alleles from 32 individuals, the mean expected heterozygosity was 0.663, and mean inbreeding coefficient was 0.011, consequently suggesting that the present broodstock has retained the high level of genetic diversity. However, our analysis also recommended the collection of more broodfish for more stable brood line, since the estimated value of the effective population size was proven to be 35. The average probability of identity was $6.85{\times}10^{-11}$. NE-2P and NE-PP of paternity non-exclusion probabilities were 0.00835 and 0.00027, respectively. As the result of principle coordinate analysis, the genotype of broodstock was not overlapped, suggesting that the management system of giant grouper based on eight selected microsatellite markers might be effective, although further validation with extended number of broodfish might also be needed in future. Data of present study could be a useful basis to avoid the unwanted selection of broodfish that possess close genetic relationship with current broodstock, and consequently to establish effective broodstock management system allowing the production of progeny with high genetic diversity.

The Modified Coefficient of the Orthotropic Rigidity for Stiffened Plates with Open Ribs (개단면 리브를 갖는 보강판의 직교이방성 강성 수정 계수)

  • Chu, Seok Beom;Choi, Young
    • Journal of Korean Society of Steel Construction
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    • v.17 no.1 s.74
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    • pp.23-32
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    • 2005
  • In this paper, the modified coefficient of the orthotropic rigidity for stiffened plates with open ribs is proposed to improve the inaccurate results of the orthotropic plate analysis. For stiffened plates with rectangular and angle ribs having various aspect ratios and boundary conditions, the aspect ratio and the rigidity ratio are selected as parameters and the parametric study on the modified coefficient is performed. Analyzed results of stiffened plates modeling with the isotropic and orthotropic plate element show that the modified coefficient can be expressed as a function of the rigidity ratio for each rib space regardless of the aspect ratio in case of the aspect ratio under 1 and can be represented as a single union function without regard to rib spaces and aspect ratios in the other case. The results also shows that the effects of the boundary condition on the modified coefficient is small and coefficient functions have different values according to rib shapes. The application to examples shows that the modified coefficient of the orthotropic rigidity improves accuracy. Therefore, the orthotropic plate analysis of stiffened plates with open ribs can easily achieve more accurate results using the coefficient function proposed in this study

Current Status of Plastic Recycling in Korea (국내 플라스틱 리싸이클링 현황)

  • Lee, Sang-hun
    • Resources Recycling
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    • v.28 no.6
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    • pp.3-8
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    • 2019
  • Recently, plastic waste in Korea has been recognized as a critical issue due to an increase in massive production of plastics, difficulty in disposal of waste plastics, and public recognition of toxicity in micro-plastics, etc. To resolve those problems, the regulation to reduce plastics consumption may be primarily considered but, in this case, clarification should be made on the rationales and the action plans in the regulation for individual waste plastic items. Another problem is the small capital sizes of domestic recycling companies, which leads to poor R&D capacity, low recycling yields and thus lowering values of recycling items. This adversely affects consumers' perception. The R&D toward recycling technical progress should take into account the environmental friendliness and recyclability from the early product design stages. Certainly, this should be supported in governmental policy and public action plans. In addition, by referring to advanced policies of i.e. European Union, the recycling industry should be recognized as an opportunity toward new investment & employment. If necessary, the regulation of plastic consumption through a formal evaluation process such as Life Cycle Assessment (LCA) will also be helpful. The values of recycled plastics should be improved through the identification and elimination of harmful chemical substances potentially contained in the products.

Implications in UNESCO's Concept of 'Cultural Diversity' and Its Application to the 「World Geography」 Subject (유네스코 '문화 다양성' 개념의 함축과 「세계지리」 과목에서의 실천 방안)

  • Jeon, Jong-Han
    • Journal of the Korean Geographical Society
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    • v.51 no.4
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    • pp.559-576
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    • 2016
  • The concept of 'cultural diversity' has emerged as a key concept and the buzzword of the 21st century's international community in education, science and culture sectors since UNESCO's "World Declaration on Cultural Diversity"(2001). However, the appropriate and correct implementation in educational level and in a subject scale can not be pursued without special understanding of multilateral implications of UNESCO's 'cultural diversity' because the concept of cultural diversity has been distributed to various applications according to individual scholars and institutions before the "World Declaration on Cultural Diversity" was released. The ultimate orientation of 'cultural diversity', the concept presented in "World Declaration on Cultural Diversity" is 'world peace' and 'the coexistence of various cultures of mankind'. In this regard, 'cultural diversity' has special 'educational' meaning to the next generation as well as the current one. Also, it is meaningful to take educational practices on cultural diversity in case of the "World Geography" subject in view of that international society of geographical education came up with "International Declaration of Geographical Education for Cultural Diversity" in the IGU(International Geographical Union) 2000. From this point of view, the author proposes that the 'cultural diversity' concept implies four folds of meanings as an ideology, as a symbol, as a vision, and as a epistemological turn based on the analysis of literatures on 'cultural diversity' of UNESCO, then presents an educational practice centering around the examples and its usage of teaching materials of cultural diversity.

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Evaluation of the Anti-obesity Activity of Platycodon grandiflorum Root and Curcuma longa Root Fermented with Aspergillus oryzae (도라지, 울금의 Aspergillus oryzae 발효에 의한 항비만효과 연구)

  • Kang, Yun Hwan;Kim, Kyoung Kon;Kim, Tae Woo;Yang, Chun Su;Choe, Myeon
    • Korean Journal of Food Science and Technology
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    • v.47 no.1
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    • pp.111-118
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    • 2015
  • In the present study, the phenolic compound level, antioxidant activity, and inhibition of lipid accumulation in Aspergillus oryzae-fermented water extracts of the Platycodon grandiflorum (PG) root and the Curcuma longa (CL) root were determined. Total polyphenol and flavonoid contents were decreased after fermentation. However, the flavonoid content of the fermented PG (FPG) was increased by 2.9-fold that of the PG before fermentation. In addition, the antioxidant activities were significantly decreased following fermentation. The potential anti-obesity activity was assessed by determining lipid accumulation and mRNA expression of sterol regulatory element-binding protein 1c (SREBP-1c) and peroxisome proliferator-activated receptor gamma ($PPAR{\gamma}$) in 3T3-L1 cells. Aspergillus-fermented extracts of PG and CL roots decreased lipid accumulation, and mRNA expression of SREBP-1c and $PPAR{\gamma}$ in 3T3-L1 cells. These results indicate that Aspergillus fermentation augments the anti-obesity activity of PG and CL by regulating the expression of the genes involved in lipid accumulation and cell differentiation of 3T3-L1 cells.

Proof Algorithm of Erdös-Faber-Lovász Conjecture (Erdös-Faber-Lovász 추측 증명 알고리즘)

  • Lee, Sang-Un
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.15 no.1
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    • pp.269-276
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    • 2015
  • This paper proves the Erd$\ddot{o}$s-Faber-Lov$\acute{a}$sz conjecture of the vertex coloring problem, which is so far unresolved. The Erd$\ddot{o}$s-Faber-Lov$\acute{a}$sz conjecture states that "the union of k copies of k-cliques intersecting in at most one vertex pairwise is k-chromatic." i.e., x(G)=k. In a bid to prove this conjecture, this paper employs a method in which it determines the number of intersecting vertices and that of cliques that intersect at one vertex so as to count a vertex of the minimum degree ${\delta}(G)$ in the Minimum Independent Set (MIS) if both the numbers are even and to count a vertex of the maximum degree ${\Delta}(G)$ in otherwise. As a result of this algorithm, the number of MIS obtained is x(G)=k. When applied to $K_k$-clique sum intersecting graphs wherein $3{\leq}k{\leq}8$, the proposed method has proved to be successful in obtaining x(G)=k in all of them. To conclude, the Erd$\ddot{o}$s-Faber-Lov$\acute{a}$sz conjecture implying that "the k-number of $K_k$-clique sum intersecting graph is k-chromatic" is proven.

Study on GNSS Constellation Combination to Improve the Current and Future Multi-GNSS Navigation Performance

  • Seok, Hyojeong;Yoon, Donghwan;Lim, Cheol Soon;Park, Byungwoon;Seo, Seung-Woo;Park, Jun-Pyo
    • Journal of Positioning, Navigation, and Timing
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    • v.4 no.2
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    • pp.43-55
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    • 2015
  • In the case of satellite navigation positioning, the shielding of satellite signals is determined by the environment of the region at which a user is located, and the navigation performance is determined accordingly. The accuracy of user position determination varies depending on the dilution of precision (DOP) which is a measuring index for the geometric characteristics of visible satellites; and if the minimum visible satellites are not secured, position determination is impossible. Currently, the GLObal NAvigation Satellite system (GLONASS) of Russia is used to supplement the navigation performance of the Global Positioning System (GPS) in regions where GPS cannot be used. In addition, the European Satellite Navigation System (Galileo) of the European Union, the Chinese Satellite Navigation System (BeiDou) of China, the Quasi-Zenith Satellite System (QZSS) of Japan, and the Indian Regional Navigation Satellite System (IRNSS) of India are aimed to achieve the full operational capability (FOC) operation of the navigation system. Thus, the number of satellites available for navigation would rapidly increase, particularly in the Asian region; and when integrated navigation is performed, the improvement of navigation performance is expected to be much larger than that in other regions. To secure a stable and prompt position solution, GPS-GLONASS integrated navigation is generally performed at present. However, as available satellite navigation systems have been diversified, finding the minimum satellite constellation combination to obtain the best navigation performance has recently become an issue. For this purpose, it is necessary to examine and predict the navigation performance that could be obtained by the addition of the third satellite navigation system in addition to GPS-GLONASS. In this study, the current status of the integrated navigation performance for various satellite constellation combinations was analyzed based on 2014, and the navigation performance in 2020 was predicted based on the FOC plan of the satellite navigation system for each country. For this prediction, the orbital elements and nominal almanac data of satellite navigation systems that can be observed in the Korean Peninsula were organized, and the minimum elevation angle expecting signal shielding was established based on Matlab and the performance was predicted in terms of DOP. In the case of integrated navigation, a time offset determination algorithm needs to be considered in order to estimate the clock error between navigation systems, and it was analyzed using two kinds of methods: a satellite navigation message based estimation method and a receiver based method where a user directly performs estimation. This simulation is expected to be used as an index for the establishment of the minimum satellite constellation for obtaining the best navigation performance.

Treatment outcome of hepatic re-irradiation in patients with hepatocellular carcinoma

  • Seol, Seung Won;Yu, Jeong Il;Park, Hee Chul;Lim, Do Hoon;Oh, Dongryul;Noh, Jae Myoung;Cho, Won Kyung;Paik, Seung Woon
    • Radiation Oncology Journal
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    • v.33 no.4
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    • pp.276-283
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    • 2015
  • Purpose: We evaluated the efficacy and toxicity of repeated high dose 3-dimensional conformal radiation therapy (3D-CRT) for patients with unresectable hepatocellular carcinoma. Materials and Methods: Between 1998 and 2011, 45 patients received hepatic re-irradiation with high dose 3D-CRT in Samsung Medical Center. After excluding two ineligible patients, 43 patients were retrospectively reviewed. RT was delivered with palliative or salvage intent, and equivalent dose of 2 Gy fractions for ${\alpha}/{\beta}=10Gy$ ranged from $31.25Gy_{10}$ to $93.75Gy_{10}$ (median, $44Gy_{10}$). Tumor response and toxicity were evaluated based on the modified Response Evaluation Criteria in Solid Tumors criteria and the Common Terminology Criteria for Adverse Events (CTCAE) ver. 4.0. Results: The median follow-up duration was 11.2 months (range, 4.1 to 58.3 months). An objective tumor response rate was 62.8%. The tumor response rates were 81.0% and 45.5% in patients receiving ${\geq}45Gy_{10}$ and $<45Gy_{10}$, respectively (p = 0.016). The median overall survival (OS) of all patients was 11.2 months. The OS was significantly affected by the Child-Pugh class as 14.2 months vs. 6.1 months (Child-Pugh A vs. B, p < 0.001), and modified Union for International Cancer Control (UICC) T stage as 15.6 months vs. 8.3 months (T1-3 vs. T4, p = 0.004), respectively. Grade III toxicities were developed in two patients, both of whom received ${\geq}50Gy_{10}$. Conclusion: Hepatic re-irradiation may be an effective and tolerable treatment for patients who are not eligible for further local treatment modalities, especially in patients with Child-Pugh A and T1-3.

Policy Suggestions to Korea from a Comparison Study of the United States, the United Kingdom, Germany, the Netherlands, and Denmark's Polices on Risk Assessment of Contaminated Soils (토양오염 지역의 위해성 평가에 관한 외국 정책의 비교분석 및 우리나라의 정책 개선에 관한 고찰)

  • Park Yong-Ha;Yang Jay-E.;Ok Yong-Sik
    • Journal of Soil and Groundwater Environment
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    • v.10 no.5
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    • pp.1-10
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    • 2005
  • Policies of the United States, the United Kingdom, the Netherlands, Germany and Denmark were compared and analyzed on risk assessment of contaminated sites. These countries were chosen from a feasible preliminary analysis of 18 countries of the European Union and the U. S. All the countries selected met two major criteria : I) implementation of risk assessment to determine the soil contamination and remediation targets of contaminated sites, ii) use of soil guidance values and risk assessment as complementary measures to determine soil contamination. Suggested policy improvements to Korea regarding these issues include i) legislation of a rational risk assessment methodology of contaminated sites, and ii) enactment of collaboration of risk assessment with the soil guidance values. To establish effective risk assessment legislation, additional in-depth research on social, economic and long-term effects of the proposed risk assessment methodologies, as well as the mutual consent of all parties including academia, industry, and administration will be necessary. Linking risk assessment with soil guidance values would be applicable to a site contaminated where the contaminant concentration exceeds a certain soil guidance value. In parallel, application of risk assessment to a site where a contaminant concentration is naturally different such as mining sites would be plausible. The policy suggestions above are not yet conclusive due to a lack of policy implementation, and simulation. Thus, additional research on developing risk assessment methodology is needed. Nevertheless, initiation of the suggested policy would increase the efficacy of Korean policy regarding the survey and remediation of contaminated sites.

A Study on the Architectural Education System for Globalization (국제화시대에 대비한 우리나라 건축교육제도 개선 연구)

  • Yim Chang-Bok
    • Journal of Engineering Education Research
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    • v.2 no.1
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    • pp.39-50
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    • 1999
  • In recent globalization era, Korean architectural education and profession are emerging as the fields with serious problems. There are two major reasons. One is an internal factor caused by Ministry of Education's full scale shift from department to faculty system. Due to the drastic change in this system, most of schools have serious difficulties to deliver the proper professional education. And the other is an external factor. In WTO era, Union of International Architects has adopted $\ulcorner$UIA Accord on Recommended International Standards of Professionalism In Architectural Practice$\lrcorner$. According to the education section of the Accord, it requires 5 years of professional education in the accredited school. So, if it is formally adopted in the Beijing Congress, which is scheduled to be held in June 1999, we may face very serious problems in architectural education. As mentioned above, with the present education system it is believed not easy to meet their new criteria. Within the present system, which does not have any mandatory relationship with professional licence, students might go on to diverse fields such as architectural design, structural engineering, construction management and building equipment engineering. However, if UIA Accord and Engineering Accreditation are required at the same time, it will not be easy to meet their new criteria with present architectural education system. The goal of this paper is to suggest the models to meet the standards of international community while keeping the strengths of existing systems.

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