• Clinical and Experimental Pediatrics
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• 제59권sup1호
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• pp.129-132
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• 2016

Ictal tachycardia and bradycardia are common arrhythmias; however, ictal sinus pause and asystole are rare. Ictal arrhythmia is mostly reported in adults with temporal lobe epilepsy. Recently, ictal arrhythmia was recognized as a major warning sign of sudden unexpected death in epilepsy. We present an interesting case of a child with ictal sinus pause and asystole. A 27-month-old girl was hospitalized due to 5 episodes of convulsions during the past 2 days. Results of routine electroencephalography (EEG) were normal, but she experienced brief generalized tonic seizure for 3 days. During video-monitored EEG and echocardiography (ECG), she showed multiple myoclonic seizures simultaneously or independently, as well as frequent sinus pauses. After treatment with valproic acid, myoclonus and generalized tonic seizures were well controlled and only 2 sinus pauses were seen on 24-hour Holter ECG monitoring. Sinus dysfunction should be recognized on EEG, and it can sometimes be treated successfully with only antiepileptic medication.

• 대한불안의학회지
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• 제12권1호
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• pp.21-27
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• 2016

Objective : The aim of this study was to investigate the relationship between subjective sleep problems and various types of traumatic events of patients with depressive disorder. Methods : A total of 411 patients diagnosed with depressive disorders were recruited in this study. The participants filled out Life Time Events Checklist (LEC), Pittsburgh Sleep Quality Index (PSQI), Beck Depression Inventory (BDI), and State-Trait Anxiety Inventory (STAI). We used the independent t-test and analysis of covariance to compare each component of PSQI between depressive patients with and without traumatic experiences. Results : The groups of patients who experienced a serious accident at work, home or during recreational activity, sexual assault, other unwanted or uncomfortable sexual experience, life-threatening illness or injury, and sudden, unexpected death of a near and dear one showed lower scores in a few components of PSQI. Sleep disturbance was a common problem in all five groups. Lower subjective sleep quality and longer sleep latency was observed in three groups. There were no differences in the other components of PSQI among groups. Conclusion : This study showed that various types of traumatic events may have different effects on subjective sleep quality as a consequence of the traumatic event which they had experienced.

• The Korean Journal of Legal Medicine
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• 제42권4호
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• pp.153-158
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• 2018

Staphylococcus aureus is an important cause of human infections, and it is also a commensal that colonizes the nose, axillae, vagina, throat, or skin surfaces. S. aureus has increasingly been recognized as a cause of severe invasive illness, and individuals colonized with this pathogen are subsequently at increased risk of its infections. S. aureus infection is a major cause of skin, soft tissue, respiratory, bone, joint, and endovascular disorders, and staphylococcal bacteremia may cause abscess, endocarditis, pneumonia, metastatic infection, foreign body infection, or sepsis. The authors describe a case of a fisherman who died of sepsis on a fishing boat during sailing out for fish. The autopsy shows paravertebral abscess, pus in the pericardial sac, infective endocarditis with vegetation on the aortic valve cusp, myocarditis, pneumonia and nephritis with bacterial colonization, and also liver cirrhosis and multiple gastric ulcerations.

• 미술이론과 현장
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• 제2호
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• pp.7-26
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• 2004

Since the 20th century, it was often announced that a painting was dead, but it is still alive. Even in the epoch of recently increasing virtuality, painting is still appealing, consistently pursed by many with a thirst. Thus, it is said that the mission of a picture is to maintain its reality without being trapped in virtuality. In the history of Western painting spanning over several hundreds of years the myriad of techniques and styles have emerged, going though a huge variety of changes: namely, its not possible any longer to find the new ways of expression in painting. Hence, painters today feel that it becomes more gradually difficult for them to execute something. In the midst of swiftly changing, diversely evolving trends of contemporary art, the painters incessantly pose a question why they go on working on painting, and seek to find its answer. Why the painters still try to say something about painting? Is that because they consider it the quintessence of fine arts or think that it is in no way possible or meaningful to comment on fine arts without relying on painting? If then, is there any avenue of escape for the painting? The question of the 'crisis of painting' is still raised, when reviewing the rapidly changing conditions of inventing artworks. That is also why the recent works failed to offer a conceptually unified, universally shared perspective of painting. Moreover, painting is left to shrink comparatively with the pervasive existence of videos and installations briskly employing digital images and technologies in their creations. Whats more problematic is the fact that there is a growing sense of crisis not only in the sphere of painting hut also in the entire realm of art. As the organizers and curators of big-scale exhibitions and art projects tend to exploit their space spectacularly, focusing primarily on their abilities to control the space, there is a pervasive notion amongst them that painting is a medium that is not properly to suit such purposes and requests. Today, the death of painting is, in fact, the death of modernist painting, which assumed a central role in the history of art for a considerable amount of time, rather than the death of painting itself. Employing a new paradigm of invention, a picture is now entering a new domain which is perhaps unknown to us. Moving beyond the stereotypical concepts of painting, physical property and flatness, pictures today reveal the introduction of time and space and the penetration of new media such as installation, photography, video and the Internet. Despite such trends, the dexterity and tactile capability of painters is still to be considered significant in the future. The renewal of painting is made in an entirely unexpected manner and place.

• 대한수사과학회지
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• 제2권2호
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• pp.50-66
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• 2007

사건 사고현장에서 가장 먼저 접근하는 초동조치 활동은 원인을 규명하는데 결정적인 역할을 한다. 법의학적 지식이 부족한 자가 최초현장에 접근하여 결정적인 사건해결 증거를 멸실케 한다면 억울한 죽음은 물론이고 무고한 혐의자를 발생시키며 유사범죄의 발생을 막을 수 없을 것이다. 본 연구는 119구급대 응급구조사에 대한 법의학교육의 필요성을 제시하고자 전국 대학(교) 응급구조학과 및 2급 양성기관의 법의학교육 실태분석을 위한 조사를 시행하였으며, 119구급대원 중 1 2급 응급구조사 307명(1급 43%, 2급 57%)을 대상으로 설문조사를 실시하였다. 그 결과 업무 중 범죄와 관련된 경험 94.8%, 죽음(변사체)의 경험이 91.9%였고, 이러한 현장에 92.8%가 경찰보다 먼저 현장에 도착하였다. 응답자의 72%는 법의학지식이 부족하여 업무 중에 어려움을 겪은 경험이 있었고, 수사경찰관과 문제, 법적증언, 유가족과의 문제 등을 경험하였다. 90.9%는 응급구조사의 업무수행에 법의학관련 지식이 도움이 된다고 긍정적으로 밝혔으며, 법의학교수에 의해 정기적인 교육을 희망하고 있었다. 응급구조사들의 법의학적 검시관련 지식을 알아보기 위해 국가 및 지방자치단체가 억울한 죽음이 없도록 감시하고, 정책적 차원에서 법의학적인 검시가 필요한 것에 대한 질문에 1급 2급 응급구조사 두 군 모두 20개 항목 중 각각 8.86개와 7.99개만 인식하고 있어, 법의학교육이 절실히 필요한 것으로 나타났다. 따라서 법의학은 응급구조사에게 단순히 범죄와 관련된 상황에서만 필요한 것이 아니라 각종 대량재해 교통사고 보험관련 사고 산업재해 등의 죽음과 관련된 법률적 문제를 해결하는 데에도 연관되어 있다. 신고체계가 다원화 되어 있는 우리나라 현실에서 119구급대의 응급구조사들은 의학적 판단에 기초한 신속하고 정확한 응급처치와 더불어 현장을 보존하고 결정적 사건해결의 물적 증거 보존을 위한 법의학적 지식을 가지기 위해서는 체계적인 법의학교육이 시행되어져야 할 것이다.

• Environmental Analysis Health and Toxicology
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• 제17권2호
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• pp.109-115
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• 2002

This study was conducted to investigate the reference value of mercury (Hg) in liver and kidney of Korean population. The mercury concentration in 244‘sudden and unexpected death’autopsies (male: 180, female: 64) aged from 0 to 87 years was analyzed. The concentration of mercury was measured by atomic absorption spectrophotometer (Perkin-Elmer Model 5100) with mercury/hydride generating system (FIAS 400). The contents of mercury in liver and kidney fitted well the log-normal distribution rather than normal distribution. Geometric mean concentration of mercury in liver and kidney was 0.115 $\mu\textrm{g}$/g wet weight and 0.149 $\mu\textrm{g}$/g wet weight, respectively. Geometric mean concentration of mercury in female was higher than in male (p < 0.01). The mercury content in liver and kidney increased with age up to the forties and slightly decreased there-after. The regression model of mercury deposit in liver and kidney by age was predicted as the following equation : Log LHg : -1.0576＋0.0045$.$Age-0.0001$.$Age$^2$＋0.0873$.$Sex, Log KHg = -1.0576＋0.0152$.$Age-0.0002$.$Age$^2$＋0.1935$.$Sex. The liver burden of mercury was estimated to be 158.3∼161.3 $\mu\textrm{g}$ in male and 163.0∼166.9 $\mu\textrm{g}$ in female. The kidney burden of mercury was estimated to be 42.0∼42.9 $\mu\textrm{g}$ in male and 55.5∼57.1 $\mu\textrm{g}$ in female.

• 논리연구
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• 제13권2호
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• pp.27-59
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• 2010

작년 7월 28일 고(故) 김영정 교수의 갑작스러운 별세 이후 4편의 미발표 논문이 발견되었다. 그 논문에는 김영정 교수의 원대한 계획이 있었음이 확인되었다. 특히 그의 독자적인 개념과 이론이 확인되었는데, 김영정 교수가 "선제논리" 또는 "장논리"라고 부르는 것이다. 이 글에서는 김영정 교수의 그 계획을 "선제논리 프로그램"이라고 부르고자 한다. 김영정 교수는 논리학과 비판적 사고의 더욱 밀접한 연관관계의 필요성과 가능성을 실현하기 위하여 선제논리라는 새로운 논리체계를 모색하였다. 이 글에서는 김영정 교수의 "선제"와 선제논리가 무엇인지(2절), 왜 김영정 교수가 논리학의 관점에서 선제논리가 필요하다고 보았는지를(3절) 살펴볼 것이다. 이렇게 함으로써 우리는 김영정 교수가 마지막 학문적 열정과 투혼을 쏟아 부었던 작업 내용의 얼개를 파악할 수 있다. 이러한 파악을 바탕으로 나는 김영정 교수로 하여금 최후까지 고뇌에 싸이게 했던 문제를 비판적으로 조명하고자 한다(4절, 5절).

• 항공우주정책ㆍ법학회지
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• 제5권
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• pp.119-169
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• 1993

In this article the present writers have surveyed recent cases on Warsaw Convention especially on the cases emerged in the years between 1986 to 1993. The cases before 1986 were discussed already in the book titled "Liability of International Air Carrier," written by Professor Choi, published in Seoul 1986. In this article the writers have reviewed most of the American cases and some cases from the courts of Germany, France and England. Main subjects which were discussed herein were as follows: Liability of air carriers in Warsaw Convention carriage 1. Exclusivity of the Warsaw Convention as a remedy 2. Warsaw Jurisdiction 3. The scope of the Warsaw Convention's definition of "Accident" under Article 17 of the Warsaw Convention (1) Mental anguish (2) Unusual or unexpected events 4. Adequacy of notice of the limitation of liability to passengers for injuries and death 5. Damages recoverable, punitive damages and burden of proof 6. The wilful misconduct exception; definition of wilful misconduct 7. Cargo and passenger baggage 8. Time limitation of actions After examining articles published world-wide, this article compiles and analyses recent cases involving the Warsaw Convention system. As Warsaw System is based on international convention, maintaining uniformity in interpretation is of utmost importance. Therefore, this type of study is essential for resolving air-transportation disputes in Korea. This article examines the current state and recommends the desired course for the Warsaw Convention. The writers hope that this article is helpful to the Korean courts and those in the air-transportation industry in interpreting the Warsaw Convention.

• Macromolecular Research
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• 제16권8호
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• pp.695-703
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• 2008

Nanoparticles have tremendous potential in cancer prevention, detection and augmenting existing treatments. They can target tumors, carry imaging capability to document the presence of tumors, sense pathophysiological defects in tumor cells, deliver therapeutic genes or drugs based on the tumor characteristics, respond to external triggers to release an appropriate agent, document the tumor response, and identify the residual tumor cells. Nanoparticles < 30 nanometers in diameter show unexpected and unique properties. Furthermore, particles < 5 nanometers in size can easily penetrate cells as well as living tissues and organs. This study evaluated the safety of nano materials in a living body and the relationship between the living tissue and synthetic nano materials by examining the in-vitro cytotoxicity of poly(lactic-co-glycolic) acid (PLGA) nano-spheres and fluorescein isothiocynate(FITC)-labeled dendrimers as polymer nanoparticles. PLGA was chosen because it has been used extensively for biodegradable nanoparticles on account of its outstanding bio-compatibility and its acceptance as an FDA approved material. The dendrimer was chosen because it can carry a molecule that recognizes cancer cells, a therapeutic agent that can kill those cells, and a molecule that recognizes the signals of cell death. Cytotoxicity in L929 mouse fibroblasts was monitored using MTT assay. Microscopic observations were also carried out to observe cell growth. All assays yielded meaningful results and the PLGA nanoparticles showed less cytotoxicity than the dendrimer. These nano-particles ranged in size from 10 to 100 nm according to microscopy and spectroscopic methods.

• The Korean Journal of Legal Medicine
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• 제40권2호
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• pp.61-64
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• 2016

Ehlers-Danlos syndrome type IV (EDS IV) is a hereditary disorder of the connective tissue, characterized by easy bruising, thin skin with visible veins, and spontaneous rupture of the large arteries, uterus, or bowel. EDS IV is caused by mutations of the gene for type III procollagen (COL3A1), resulting in insufficient collagen production or a defect in the structure of collagen. EDS IV can have fatal complications such as the rupture of great vessels or organs, which can cause hemorrhaging and sudden unexpected death. Here, we report a case of a 43-year-old female who collapsed after a struggle with a neighbor. In this patient, the bifurcation of the bilateral common iliac artery ruptured, with no evidence of trauma, inflammation, or atherosclerosis. Genetic analysis of COL3A1 showed the presence of a c.2771G>A (p.Gly924Arg) mutation, which may be associated with EDS IV. The forensic pathologist should consider the possibility that the spontaneous visceral or arterial rupture was caused by EDS IV. Genetic analysis is not currently a routine procedure during autopsy. However, in this case, we suggest that the patient possibly had an underlying EDS IV condition, and we recommended family members of the deceased to seek genetic analysis and counseling.