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Reference Value of Mercury in Liver and Kidney of Korean  

최병선 (중앙대학교 의과대학 예방의학교실)
박영주 (중앙대학교 의과대학 예방의학교실)
권일훈 (국립과학수사연구소)
홍연표 (중앙대학교 의과대학 예방의학교실)
박정덕 (중앙대학교 의과대학 예방의학교실)
Publication Information
Environmental Analysis Health and Toxicology / v.17, no.2, 2002 , pp. 109-115 More about this Journal
Abstract
This study was conducted to investigate the reference value of mercury (Hg) in liver and kidney of Korean population. The mercury concentration in 244‘sudden and unexpected death’autopsies (male: 180, female: 64) aged from 0 to 87 years was analyzed. The concentration of mercury was measured by atomic absorption spectrophotometer (Perkin-Elmer Model 5100) with mercury/hydride generating system (FIAS 400). The contents of mercury in liver and kidney fitted well the log-normal distribution rather than normal distribution. Geometric mean concentration of mercury in liver and kidney was 0.115 $\mu\textrm{g}$/g wet weight and 0.149 $\mu\textrm{g}$/g wet weight, respectively. Geometric mean concentration of mercury in female was higher than in male (p < 0.01). The mercury content in liver and kidney increased with age up to the forties and slightly decreased there-after. The regression model of mercury deposit in liver and kidney by age was predicted as the following equation : Log LHg : -1.0576＋0.0045$.$Age-0.0001$.$Age$^2$＋0.0873$.$Sex, Log KHg = -1.0576＋0.0152$.$Age-0.0002$.$Age$^2$＋0.1935$.$Sex. The liver burden of mercury was estimated to be 158.3∼161.3 $\mu\textrm{g}$ in male and 163.0∼166.9 $\mu\textrm{g}$ in female. The kidney burden of mercury was estimated to be 42.0∼42.9 $\mu\textrm{g}$ in male and 55.5∼57.1 $\mu\textrm{g}$ in female.
Keywords
Reference value; Mercury; Liver; Kidney; Korean;
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Times Cited By KSCI : 1  (Citation Analysis)
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