• Title/Summary/Keyword: under 40 years old

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A COMPARATIVE STUDY ON THE VITAL SIGN AND BEHAVIOR APPEARANCE DEPENDING ON THE ROUTE OF FLUMAZENIL ADMINISTRATION IN CONSCIOUS SEDATION BY MIDAZOLAM (Midazolam을 이용한 의식진정시 flumazenil의 투여경로에 따른 생징후 및 행동양상의 비교 연구)

  • Kim, Hyun-Sik;Lee, Chang-Seop;Lee, Sang-Ho
    • Journal of the korean academy of Pediatric Dentistry
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    • v.29 no.2
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    • pp.159-167
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    • 2002
  • The purpose of this study was to evaluate the efficacy and safety depending on the route of flumazenil, as an antagonist against midazolam. The subjects of this study were 15 volunteers of $22{\sim}24$ years old. They were sedated with midazolam 0.2mg/Kg intranasal spray, and then 40 minutes after midazolam administration, they were given flumazenil 0.2mg intranasal spray for their reversal. For evaluation of the efficacy and safety of intranasal spray for flumazenil, they were monitored with pulse-oxymeter(Nellcor symphony N-3000, Nellcor Puritan CO. USA) and electric sphygmomanometer (Heartcare 200, National CO. Japan), and were assessed themselves using visual analogue scale(VAS) for tranquilization, sleep, fatigue and attitude. All of these subjects were reduced completely without any undesired situations. The results from this study can be summarized as follows ; 1. Nasaly administered flumazenil using spray device produced much more rapid reduction than intravenously administered flumazenil, but soon after fell in more deep sedated state than intravenously administered flumazenil. 2. There were no considerable side effects or bad influence on vital signs of both nasaly administered flumazenil and intravenously administered flumazenil. These results suggested that the flumazenil administered nasaly using spray device for reversal, we could treat patients safely and effectively under conscious sedation using midazolam administration. But, We will have to research about its optimal dosages for flumazenil, used as intranasal spray for reversal agents against the midazolam by evaluating the blood plasma concentration of midazolam and flumazenil.

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Walking Accident Characteristics and Walking Factors for Road Crossing of the Transportation Vulnerable in the Case of Yeosu (교통약자의 보행 교통사고 특성과 보행 횡단요소 분석 (여수시를 사례로))

  • Kim, Sang Gu
    • Journal of Digital Convergence
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    • v.14 no.6
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    • pp.439-448
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    • 2016
  • The population over 65 years old is 12.7% of total population in 2014 and Korea is going to be an aged society in the near future. The transportation vulnerable including the aged should be guaranteed in walking mobility under safe and comfortable environment for their socio-economic activities. For the era of fusion and convergence this paper investigated the characteristics of walking accidents related to the aged pedestrians and analyzed the aged-oriented walking factors with a reaction time and a walking speed at crosswalks in Yeosu. In the results, the crashes for the aged occur at 9.9% of total crashes and the fatalities of the aged are 40.3% of total fatalities in 2014. The 47.4% of the aged fatalities is also attributed to vehicle-to-pedestrian accidents. The 49.3% of all pedestrian fatalities occurs at the aged pedestrians with a very high proportion. The reaction time and walking speed for the aged were determined as the values located at the lower 15%-tile of the elderly physical ability. It is shown that the reaction time is 4.56 seconds and the walking speed is 0.76 m/s in the case of Yeosu. From two factors' standpoint, the walking environment at crosswalks in Yeosu is inappropriate for the aged.

Distribution of Sexually Transmitted Viral Diseases in Busan (부산지역 바이러스성 성병 감염양상 연구)

  • Cho, Kyung-Soon;Na, Young-Ran;Joe, Hyeon-Cheol;Lee, Jung-Hee;Jung, Myung-Ju
    • Korean Journal of Microbiology
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    • v.42 no.3
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    • pp.177-184
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    • 2006
  • This study was performed to evaluate the prevalence of high risk Human papilloma virus (HPV), Herpes simplex virus type 1, 2 (HSV-1,2), Hepatitis B virus (HBV) and Human Immuno deficiency virus (HIV) infection with sexual transmitted viral diseases in Busan during 2004 to 2005. six hundred seventy four samples of cervical swabs were tested for sexually transmitted viral diseases. Among the isolated viruses, 23 (3.4%) samples were HPV and 3 (0.4%) and 9 (1.3%) samples were HSV 1 and 2, respectively. Among the 586 serum samples tested for viruses, HSV IgM 121 (3.6%), HSV-1 IgG 487 (83.1%), HSV-2 IgG 135 (23.0%), HBsAg 26 (4.4%), HBeAg 7 (1.2%), and HIV (0%) types were found. HPV genotypes were detected in 16 patients, of which 13 cases were high risk type HPV, 3 cases were low risk type HPV, and multi infection were detected in 7 cases. In the age distribution of the patients, 7.2% of infection tested from cervical swabs occurred in under the age of 20, while 100% of infection was found to occur in those who were 40 years old or older in the serum samples. The outbreak pattern in their occupations was found to be the highest at the health organization (amusement quarter) for the cervical swabs, and at infirmary (commercial sex worker) for the serum samples, respectively.

Emission Rates Estimation by Vehicle Type in Seoul Using the Vehicle Inspection Data (차량 검사 데이터를 활용한 서울시 자동차 유형별 배출 가스량 원단위 산정)

  • Lee, Hyosun;Han, Yohee;Park, Shin Hyoung;Hwang, Ho Hyun;Kim, Youngchan
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.20 no.6
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    • pp.177-191
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    • 2021
  • One of the major causes of serious air pollution worldwide is emissions from road transportation. A number of countries are working to reduce vehicle emissions, and the Seoul Metropolitan Government is also implementing active policies to reduce emissions by setting a target of 40% by 2030. Implementing these policies requires the introduction of practical indicators. Most of the domestic emissions are calculated by the emission coefficient, a function of speed at the National Institute of Environmental Research under the Ministry of Environment, but the dynamic variable speed is limited to being used as an indicator of the number of eco-friendly vehicles. Therefore, this study calculated the emission rates in Seoul using the vehicle registration data of Seoul and the vehicle inspection data from the Korea Transportation Safety Authority. The tendency of emissions was determined according to key variables such as vehicle type, fuel and mileage. Emissions were based on carbon monoxide, hydrocarbons, nitrogen oxides and particulate matter measured by vehicle inspection from the Korea Transportation Safety Authority. As a result, the emission rates showed a significant trend according to the model year and mileage. This can be used as a policy indicator to preferentially switch commercial vehicles with old model years and long mileage when switching eco-friendly vehicles in Seoul.

Geochemical Evolution of CO2-rich Groundwater in the Jungwon Area (중원 지역 탄산수의 지구화학적 진화)

  • 고용권
    • Economic and Environmental Geology
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    • v.32 no.5
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    • pp.469-483
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    • 1999
  • Two different types of deep groundwaters occur together in the Jungwon area: $CO_2$-rich water and alkali water. Each water shows distrinct hydrogeochemical and environmental isotopic characteristics. The $CO_2$-rich waters are characterized by lower pH(6.0~6.4), higher Eh (25~85mV) and higher TDS content (up to 3,300 mg/l), whereas the alkali type waters have higher pH (9.1~9.5), lower Eh (-136~-128mV) and lower TDS content (168~254 mg/l). The CO2-rich waters ($Pco_2$=up to 1atm) were probably evolved by the local supply of deep $CO_2$ during the deep circulation, resulting in enhanced dissolution of surrounding rocks to yield high concentrations of $Ca^{2+}, Na^+, Mg^{2+}, K^+\; and \;HCO_3\;^-$ under low pH conditions. On the other hand, the alkali type waters ($Pco_2$=about 10-4.6 atm) were evolved through lesser degrees of simple wate/rock (granite) interaction under the limited suppy of $CO_2$. The alkali waters are relatively enriched in F- (up to 14mg/l), whereas the F- concentration of$CO_2$-rich water is lower (2.2~4.8 mg/l) due to the buffering by precipitation of fluorite. The oxygen-hydrogen isotopes and tritium data indicate that compared to shaltion ($\delta$18O=-9.5~-7.8$\textperthousand$),two different types fo deep groudwaters (<1.0TU)were both derived from pre-thermonuclear (more than 40 years old) meteoric waters with lighter O-H isotopic composition ($\delta$18O=-9.5~-7.8$\textperthousand$) and have evolved through prolonged water/rock interaction. The $CO_2$-rich waters also show some degrees of isotopic re-equilibration with $CO_2$ gas. The $\delta^{34}S$ values of dissolved sulfates (+24.2~+27.6$\textperthousand$) in the $CO_2$-rich waters suggest the reduction of sulfate by organic activity at depths. The carbon isotope data show that dissolved carbon in the $CO_2$-rich waters were possibly derived either from dissolution of calcite or from deep $CO_2$ gas. However, strontium isotope data indicate Ca in the $CO_2$-rich waters were derived mainly from plagioclase in granite, not from hydrothermal calcites.

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DENTAL TREATMENT OF A PATIENT WITH CATCH22 SYNDROME UNDER GENERAL ANESTHESIA: A CASE REPORT (CATCH22 syndrome 환아의 전신마취 하 치아우식 치료: 증례보고)

  • Kim, Min Jin;Song, Ji-Soo;Shin, Teo Jeon;Kim, Young-Jae;Kim, Jung-Wook;Jang, Ki-Taeg;Lee, Sang-Hoon;Hyun, Hong-Keun
    • The Journal of Korea Assosiation for Disability and Oral Health
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    • v.14 no.1
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    • pp.36-40
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    • 2018
  • CATCH22 syndrome or DiGeorge syndrome is a medical acronym of cardiac defects, abnormal facial appearances, thymic hypoplasia, cleft palate, and hypocalcemia. Patients with CATCH22 syndrome are susceptible to infection due to an absent or hypoplastic thymus and often have difficulties in maintaining good oral hygiene, which may require dental treatment. We present a case of dental treatment for the uncooperative child with CATCH22 syndrome under general anesthesia. A 4-year-old, 14.8 kg boy with CATCH22 syndrome visited Seoul National University Dental Hospital for dental check up. The patient had multiple caries requiring dental treatment. He experienced the corrective heart surgery due to Tetralogy of Fallot a few years ago. General anesthesia was planned because his heart rate and vital sign had shown unstable during the previous conscious sedation procedure. Dental restorative treatments were successfully performed and no complications were observed during and after the procedure. Safe and effective dental management of the patients with CATCH22 syndrome could be performed with the help of general anesthesia and careful monitoring.

Benthic Foraminiferal Assemblage and Sedimentary Environment of Core Sediments from the Northern Shelf of the East China Sea (북동중국해 대륙붕 코아 퇴적물의 저서유공충 군집 특성과 퇴적환경 연구)

  • Kang, So-Ra;Lim, Dhong-Il;Kim, So-Young;Rho, Kyoung-Chan;Yoo, Hae-Soo;Jung, Hoi-Soo
    • Journal of the Korean earth science society
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    • v.29 no.6
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    • pp.454-465
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    • 2008
  • Benthic foraminiferal assemblage and AMS radiocarbon dating of core sediments from the northern shelf of the East China Sea were analyzed in order to understand the paleoenvironment and sedimentary environmental changes around the Korean marginal seas since the last glacial maximum (LGM). The core sediments, containing continuous records of the last 16,000 years, reveal a series of well-defined vertical changes in number of species (S), P/T ratio and species diversity (H) as well as foraminiferal assemblage. Such down-core variations display a sharp change at a core depth of approximately 240 cm, which corresponds to ca. 10,000 year B.P. The sediments of the lower part of the core (240${\sim}$560 cm, Zone I), including the well-developed tide-influenced sedimentary structures, are characterized by high abundances of Ammonia beccarii and Elphidium clavatum (s.l.) and low values in number of species, P/T ratio and diversity. These tide-influenced signatures and foraminiferal assemblage characters suggest that the sediments of Zone I were deposited in a coastal environment (water depths of 20${\sim}$30 m) such as tidal estuary with an influence of the paleo-rivers (e.g., old-Huanghe and Yangtze rivers) during the early phase of the sea-level rise (ca. 16,000 to 10,000 years) since the LGM. In contrast, the upper core sediments (0${\sim}$240 cm, Zone II) are characterized by abundant Eilohedra nipponica and Bolivina robusta with a minor contribution of A. ketienziensis angulata and B. marginata. and high values in number of species, P/T ratio and diversity. Based on relative abundance of these assemblage, Zone II can be divided into two subzones (IIa and IIb). Zone IIa is interpreted to be deposited under the inner-to-middle shelf environment during the marine transgression in the early Holocene (after ca. 9,000 yr B.P.) when sea level rapidly increased. The sediments of zone IIb most likely deposited after 6,000 yr B.P. under the outer shelf environment (80${\sim}$100 m water depth), which is similar to modem depositional environments. The muddy sediments of zone IIb were probably transported from the old-Huanghe and Yangtze Rivers during the late Holocene. We suggest that the present-day oceanographic conditions over the Yellow and the East China Seas have been established after ca. 7,000${\sim}$6,000 yr B.P. when the Kuroshio Current began to influence this area.

Hwaunsi(和韻詩) on the Poems of Tu Fu(杜甫) and Su Shi(蘇軾) Written by Simjae(深齋) Cho Geung-seop(曺兢燮) in the Turning Point of Modern Era (근대 전환기 심재 조긍섭의 두(杜)·소시(蘇詩) 화운시)

  • Kim, Bo-kyeong
    • (The)Study of the Eastern Classic
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    • no.56
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    • pp.35-73
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    • 2014
  • This paper examined the poem world of Simjae(深齋) Cho Geung-seop(曺兢燮: 1873-1933) in the turning point of the modern era, focused on his Hwaunsi (和韻詩: Poems written by using the rhymes of other poets' poems). In his poems, there are lots of Hwaunsi on the poems of Tu Fu(杜甫) and Su Shi(蘇軾), especially. This makes him regarded as a medieval poet, engaged in Chinese poem creation in the most traditional method in the turbulent period. Looking at the Hawunsi(和韻詩) alone, Simjae's creative life became the starting point of turnaround at around 40 years old. Before the age of 40, the poets in the Tang Dynasty and Song Dynasty and Ming Dynasty and Qing Dynasty and Korean figures like Lee Hwang(李滉), as well as Tu Fu and Su Shi were the subjects of his Hwanunsi. After the age of 40, some examples of writing poems using the rhymes of other poets' poems, especially Korean figures related to regions, are often found, reducing Hwaunsi on Tu Fu and Su Shi. Simjae called Tu Fu the integration of poets, talking about the integrity of poetic talent and his being highly proficient in mood and view. As reflecting such an awareness, the themes and moods and views are demonstrated diversely in Simjae's Hwaunsi. Although, he did not reveal his thinking about the poems of Su Shi, he seemed to love Su Shi's poems to some degree. The closeness to the original poems, the poems of Tu Fu are relatively higher than those of Su Shi. Roughly speaking, Simjae tried to find his own individuality, intending to follow Tu Fu, but, he seemed to attempt to reveal his intention using Su Shi's poems, rather than trying to imitate. To carefully examine, Simjae wrote Hwaunsi, but he did not just imitate, but revealed the aesthetics of comparison and difference. In many cases, he made new meanings by implanting his intentions in the poems, while sharing the opportunity of creation, rather than bringing the theme and mood and view as they are. The Hwaunsi on Su Shi's poems reveal the closeness to the original poems relatively less. This can be the trace of an effort to make his own theme and individuality, not being dominated by the Hwaun(和韻: using the rhymes of other poets' poems) entirely, as he used the creative method having many restrictions. However, it is noted that the Hwaunsi on Tu Fu's poems was not written much, after the age of 40. Is this the reason why he realized literary reality that he could not cope with anymore with only his effort within the Hwaunsi? For example, he wrote four poems by borrowing Su Shi's Okjungsi(獄中詩: poem written in jail) rhymes and also wrote Gujung Japje(拘中雜題), in 1919, while he was detained. In these poems, his complex contemplation and emotion, not restricted by any poet's rhymes, are revealed diversely. Simjae's Hwaunsi testifies the reality, in which Chinese poetry's habitus existed and the impressive existence mode at the turning point of the modern era. Although, the creation of Hwaunsi reflects his disposition of liking the old things, it is judged that his psychology, resisting modern characters' change, affected to some degree in the hidden side. In this regard, Simaje's Hwaunsi encounters limitation on its own, however, it has significance in that some hidden facts were revealed in the modern Chinese poetry history, which was captured with attention under the name of novelty, eccentricity and modernity.

Salmonellosis in Children in Daejeon, Korea, 1994~1999 (대전지역 살모넬라증 환아에 대한 임상적 연구(1994~1999년))

  • Chun, Jung-Soo;Lee, Kyung-Yil;Lee, Hyung-Shin;Kim, Sang-Yong;Han, Ji-Whan;Her, Jae-Kyun;Whang, Tyung-Tai
    • Pediatric Infection and Vaccine
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    • v.7 no.2
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    • pp.211-217
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    • 2000
  • Purpose : Salmonellosis including typhoid fever is still prevalent in Korea. Recently it has been reported that the incidence of salmonella gastroenteritis is increasing with a reduction of typhoid fever. We studied the clinical and laboratory features of salmonellosis. Methods : We evaluated the clinical records of 83 patients with salmonellosis who had been confirmed by stool culture from 1994 to 1999. Results : Annual incidence of salmonellosis showed an increasing tendency during recent 4 years. Seasonally, summer(45.8%) was the most prevalent, followed by fall(32.5%). Male to female ratio was 1.4 : 1. In age distribution, 64 cases(77.1%) were under 5 year-old, and 18 cases(21.7%) were younger than 1 year-old. Clinical features included diarrhea(96.4%), fever(91.6%), vomiting(49.4%), bloody stool(42.1%), abdominal pain(40.1%) and tenesmus(12.0%). In serogroups, there was no group A and group B, group C, group D(including 2 cases of S.typhi) and group E were in 41.0%(34 cases), 3.6%(3 csaes), 51.8%(43cases) and 3.6%(3 cases), respectively. In Widal test, 5 cases(13.5%) and 1 case(2.7%) of group B, C and E(total 37 cases) were observed the O titer above 1 : 80 and 1 : 320, respectively. However, in 36 cases of group D, 19 cases(52.7%) and 9 cases(25.0%) were above the O titer 1 : 80 and 1 : 320, respectively. Antibiotics resistant rates to ampicillin, trimethoprim/sulfamethoxazole and chloramphenicol were 23.2%, 10.1% and 51.4%, respectively. Conclusion : Salmonellosis has become a common cause of gastroenteritis in children, especially under the pre-school age. Isolation of salmonella is neccessary for accurate diagnosis of gastroenteritis and typhoid fever. A careful attention of the use of antibiotics is needed to reduce the muilti-drug resistant strains.

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Evaluation of a Serodiagnostic Method for Tuberculosis by Using Secreted Protein Antigens of Mycobacterium Tuberculosis (결핵균 분비항원을 이용한 결핵의 혈청학적 진단 방법에 대한 평가)

  • Bai, Gill-Han;Park, Eun-Mi;Kim, Sang-Jae
    • Tuberculosis and Respiratory Diseases
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    • v.48 no.3
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    • pp.315-323
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    • 2000
  • Background : An immunochromatographic assay (ICT Diagnostics) which facilitates the diagnosis of tuberculosis(TB) by detecting serum antibodies mainly directed against specific 38KDa of Mycobacterium tuberculosis has come into the market. The test consists of a cardboard folding device containing nitrocellulose strip and absorbent pads. The whole procedure is completed within 15 min and does not require any additional equipment. The test has been reported to be sensitive and specific in diagnosing active TB. Thus the test had been evaluated with sera from TB patients and TB-free subjects. Method : Sera from patients with active pulmonary tuberculosis(40 sputum positives for Mycobacterium tuberculosis, 79 sputum negatives, and 3 extrapulmonary tuberculosis) were obtained from the Double-Cross Chest Clinic of the Korean National Tuberculosis Association (KNTA) in Seoul. The control group consisted of TB-free 68 subjects(21 children under 7 years old and 47 healthy staff members of KNTA). Results : Nine out of 68(13.2%) TB-free controls had positive antibody response. Total 106 of 122(86.9%) radiologically active patients had positive antibodies while 16 (13.1%) showed negative reaction. Antibody was detected in 38 of 40(95.0%) sputum positive patients and 68 of 82(82.9%) sputum negative patients who were under the antituberculosis chemotherapy. The sensitivity and specificity were all 87% and the positive predictive value was 92.2% while the negative predictive value was 78.7%, when the prevalence of TB in the sample was 64.2%. Our results clearly show that the detection of antibodies which mainly react with the 38KDa antigen of M. tuberculosis is not suitable as the first-line method of diagnosis but considered only as an adjunctive test to standard techniques of tuberculosis diagnosis. when considering its high false positivity.

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