• Transactions of the Korean Society of Mechanical Engineers A
• /
• v.38 no.12
• /
• pp.1373-1377
• /
• 2014

Hot-stamping is a method of obtaining ultrahigh-strength steel by simultaneously forming and cooling boron steel in a press die after it has been heated at $900^{\circ}C$ or above. After heat treatment, boron steel has a strength of 1500 MPa or more. This material ensures a high level of quality because it overcomes the spring-back phenomenon, which is a problem associated with high-strength steel materials, and the degree of dimensional precision is improved by 90 or more because of the good formability compared with existing types of steel. In this study, the welding characteristics were identified through the butt and lap welding of hot-stamped steel using a disk laser. Full penetration was obtained at a faster speed with butt welding compared to lap welding, and a white band was observed in every specimen.

• The Korea Journal of Herbology
• /
• v.30 no.3
• /
• pp.19-24
• /
• 2015

Objectives : HPL-1, a novel herbal medicine which is composed of five herbs such as Kalopanacis Cortex, Chaenomelis Fructus, Raphani Semen, Atractylodis Rhizoma and Pulvis Aconiti Tuberis Purificatum, was developed for treatment of osteoarthritis. This study is aimed to develop analytical method for consistent quality control of HPL-1 and validate chromatographic method. Methods : Chromatographic analysis was performed using ultra-high performance liquid chromatography - diode array detector (UHPLC-DAD) equipped with RP-amide column, column oven, and auto sampler. Marker compounds [protocatechuic acid, chlorogenic acid, liriodendrin, 3,5-dicaffeoylquinic acid, ${\beta}$-D-(3-O-sinapoyl)-fructofuranosyl-$\alpha$-D-(6-O-sinapoyl)glucopyranoside and benzoylmesaconine] were separated by step gradient elution of acetonitrile and 0.1% phosphoric acid/water. The method validation was evaluated by quantitative validation parameters of linearity, accuracy, precision, limit of detection (LOD) and limit of quantification (LOQ) according to KFDA guideline.Results : An optimized method for six marker compounds in HPL-1 was established by UHPLC-DAD. The correlation coefficient (R²) with each calibration curve was greater than 0.99. The LOD and LOQ were within the range of 0.008-0.090 and $0.023-0.274{\mu}g/mL$, respectively. The relative standard deviation (RSD) of intra- and inter-day variability were less than 4.0%. The result of recovery test was range from 93.3-106.3% with RSD < 4.0%.Conclusions : These results suggest that the quantitative UHPLC method is precise, accurate, effective for quality evaluation of HPL-1. The method may also contribute to improve quality of crude drug preparations used for treatment of various diseases.

• Tribology and Lubricants
• /
• v.33 no.2
• /
• pp.52-58
• /
• 2017

An ultra-high precise ejection process is essential in a dispensing system for fabricating various precision parts such as a semiconductor, LED, and camera module. The size of such parts has been decreasing, which implies that a precise ejecting technique is required. A phosphor-containing liquid is ejected via a dispenser using dual piezoelectric actuators that are used for generating a high-speed dispensing mechanism. The rod and nozzle continuously contact in high speed to eject the liquid. However, the high-strength filler or phosphor in the liquid causes wear on the surfaces of the rod and nozzle during the dispensing process. As a result, the ejection reliability decreases as the wear on the surfaces increases. Therefore, it is necessary to estimate the wear characteristics of the rod and nozzle via an experiment and FE analysis. Reliability rests up to 1,000 cycles are conducted under relatively severe conditions. The flow rate and surfaces roughness of the rod and nozzle are measured in each ejection cycle. The surface images and wear volume are obtained before and after the tests and the ejection reliability is confirmed by measuring the flow rate of the liquid. The experimental results show that the ejection reliability is maintained up to 1,000k cycles; these results are validated by the simulation results.

• Transactions of the Korean Society of Mechanical Engineers A
• /
• v.39 no.8
• /
• pp.759-763
• /
• 2015

The laser machining process has been proposed as an advanced process for the selective fabrication of electrodes without a mask. In this study, we adapt laser machining to metals that have different thermal properties. Based on the results, the metals exhibit a different surface morphology, heat-affected zone (HAZ), and a recast layer around the machined surface according to their thermal conductivity, boiling point, and thermal diffusivity. Then, we apply ultrasonic-assisted laser machining to remove the recast layer. The ultrasonic-assisted laser machining exhibits a better surface quality in metals with higher diffusivity than those having lower diffusivity.

• Natural Product Sciences
• /
• v.26 no.1
• /
• pp.64-70
• /
• 2020

Citrus junos seeds (CS) have been traditionally used for the treatment of cancer and neuralgia. They are also used to manufacture edible oil and cosmetic perfume. A large amount of CS shells without oil (CSS) are discarded after the oil in CS is used as foods or herbal remedy. To efficiently utilize CSS as a by-products, it needs to be studied through chemical analysis. Therefore, we developed an ultra-performance liquid chromatography (UPLC)-diode array detection (DAD) method for simultaneous determination and quantitative analysis of five components (two flavonoids and threes limonoids) in CSS. A Waters Acquity UPLC HSS T3 column C18 (2.1 × 100 mm, 1.8 ㎛) was used for this separation. It was maintained at 40 ℃. The mobile phase used for the analysis was distilled water and acetonitrile with gradient elution. To identify the quantity of the five components, a mass spectrometer (MS) with an electrospray ionization (ESI) source was used. The regression equation showed great linearity, with correlation coefficient ≥ 0.9912. Limits of detection (LOD) and limits of quantification (LOQ) of the five compounds were 0.09 - 0.13 and 0.26 - 0.38 ㎍/mL, respectively. Recoveries of extraction ranged from 97.45% to 101.91%. Relative standard deviation (RSD) values of intra- and inter-day precision were 0.06 - 1.15% and 0.19 - 0.25%, respectively. This UPLC-DAD method can be validated to simultaneously analyze quantities of marker flavonoids and limonoids in CSS.

• Journal of Ginseng Research
• /
• v.40 no.4
• /
• pp.382-394
• /
• 2016

Background: Ginsenosides are the characteristic and principal components which manifest a variety of the biological and pharmacological activities of the roots and rhizomes of Panax ginseng (GRR). This study was carried out to qualitatively and quantitatively determine the ginsenosides in the cultivated and forest GRR. Methods: A rapid and sensitive ultra-high-performance liquid chromatography coupled with diode-array detector and quadrupole/time of flight tandem mass spectrometry (UPLC-DAD-QTOF-MS/MS) was applied to the qualitative analysis of ginsenosides and a 4000 QTRAP triple quadrupole tandem mass spectrometer (HPLC-ESI-MS) was applied to quantitative analysis of 19 ginsenosides. Results: In the qualitative analysis, all ingredients were separated in 10 min. A total of 131 ginsenosides were detected in cultivated and forest GRR. The method for the quantitative determination was validated for linearity, precision, and limits of detection and quantification. 19 representative ginsenosides were quantitated. The total content of all 19 ginsenosides in the forest GRR were much higher than those in the cultivated GRR, and were increased with the growing ages. Conclusion: This newly developed analysis method could be applied to the quality assessment of GRR as well as the distinction between cultivated and forest GRR.

• Transactions of the Korean Society of Mechanical Engineers B
• /
• v.35 no.11
• /
• pp.1147-1156
• /
• 2011

A contact-type area-varying capacitive displacement sensor, or CLECDiS, can measure displacements over millimeter ranges with nanometer resolution. However, a small changes in the contact condition due to the surface profile or friction, which are inherent characteristics of contact-type sensors, lead to significant distortion of the output signal. Therefore, ensuring reliable contact conditions during CLECDiS measurements is the most important area to be improved in their actual use. Herein, in order to design an instrument for ensuring reliable contact conditions, the contact condition is analyzed by characterizing the signal distortion, observing the pressure distribution between the contacting surfaces, and measuring the motional errors of the sensor using a laser Doppler vibrometer (LDV). The manufactured instrument enables a CLECDiS to be used in an ultraprecise positioning system with improved reliability.

• Journal of Korea Society of Industrial Information Systems
• /
• v.12 no.3
• /
• pp.124-131
• /
• 2007

Aspheric glass lenses was fabricated by glass molding press(GMP), which is a plano-aspheric convox shape and intended for use as an optical design of 3 megapixel and 2.5 magnifications zoom in a camera phone module. Transcription ratio of form accuracy (PV) as well as resolution properties was measured for evaluation the molded lens. Form accuracy (PV) of the mold surface was $0.127\;{\mu}m$ in an aspheric and $0.168\;{\mu}m$ in a plano, in case of the molded lens it shows $0.205\;{\mu}m$ and $0.223\;{\mu}m$, respectively. Resolution of the molded lens was measured as a MTF[Contrast]. The molded lens shows contrast of 32.9% at 80 1p/mm and the value is similar with contrast of 33% obtained simulation.

• Journal of Applied Biological Chemistry
• /
• v.59 no.2
• /
• pp.165-169
• /
• 2016

The quantitative analytical method for the bioactive substance, 3-cyano-4-methoxy-N-methyl-2-pyridone (ricinine) and an index compound, ricinoleic acid in castor plant (Ricinus communis) extract or oil was developed. For the determination of a pyridone alkaloid compound, ricinine, successive cartridge cleanup method combined with ultra-performance liquid chromatography was set up with $ENVI-Carb^{TM}$ (0.5 g) and $C_{18}$ SPE cartridges. Accuracy and precision were evaluated through fortification studies of one biopesticide (PE) at 10 and $100mg\;kg^{-1}$. Mean recoveries of ricinine were 98.7 and 96.0 % associated with less than 10 % RSD, respectively. For the determination of ricinoleic acid in castor extract and oil, saponification and methylation were optimized using gas chromatography-time of flight mass spectrometry. Recovery was more than 84.8 % associated with 6.2 % RSD after derivatization procedure. Both methodologies developed were applied to analyze real samples including three castor oil products and six commercially available biopesticides containing R. communis, collected at Korean market. The contents of ricinine and ricinoleic acid in most commercial biopesticides were less than the oil or extract contents indicated by label.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.14 no.9
• /
• pp.4130-4135
• /
• 2013

This paper is a special-purpose machine studies for processing various patterns on the surface of the stone. We have developed a special-purpose machine that can be applied in various patterns upon the surface treatment of the stone with the water jet. The special-purpose machine is Configured of Transfer mechanism, motion controller, multi-nozzle mechanism, ultra high pressure water control system and S/W. We conducted a performance evaluation experiments of the pattern. We have developed a special-purpose machine with a precision of machining error ${\pm}0.5mm$ and pattern processing of various types.