• 제목/요약/키워드: type of a ring

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다중 질량 분석법을 이용한 인체 면역글로불린 G의 N-연결 글라이칸 분석 (Tandem Mass Spectrometry of N-linked Glycans from Human Immunoglobulin G)

  • 주황수;김윤곤;장경순;김병기
    • KSBB Journal
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    • 제22권4호
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    • pp.234-238
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    • 2007
  • 본 연구에서는 전극분무 이온화-이온 포획 질량 분석기를 이용하여 인체 IgG의 N-연결 글라이칸 중 이중촉각 구조를 가지면서 비환원 말단의 갈락토오즈 개수가 0, 1, 2 개인 서로 다른 세 가지 글라이칸의 단일 쪼개짐 (MS/MS) 및 다중 쪼개짐 현상을 관찰하고 이를 구조 분석에 이용하였다. MS/MS 분석에서는 퓨코오즈가 결합된 환원 말단의 N-아세틸 글루코사민의 0,2-고리 쪼개짐으로 파생되는 조각 피크가 가장 높은 세기로 나타나는 것을 관찰할 수 있었고, 전구체 피크와 별개로 연속적인 당 단위체의 쪼개짐이 일어나는 것을 알 수 있었다. 또한 G1 글라이칸의 경우에서만 비환원 말단의 갈락토오즈와 N-아세틸글루코사민이 결합된 채 쪼개지는 현상이 일어나는 것을 관찰할 수 있었다. 다중 쪼개짐 질량 분석 기법을 이용하여 MS/MS 스펙트럼에서 나타나는 조각 피크들의 구조를 재확인할 수 있었고, 이를 트리 구조로 정리할 수 있었다. 또한 추가적인 2,4-고리 쪼개짐 현상이 환원 말단 하나 바깥쪽의 N-아세틸 글루코사민에서 공통적으로 일어나는 것을 관찰할 수 있었다. 이와 같은 다중 쪼개짐 질량 분석기법을 이용하여 보다 복잡한 구조의 글라이칸 구조 분석에 이용될 수 있을 것으로 기대된다.

섬유 근접센서를 이용한 복약 여부 평가에 관한 연구 (A Study of Medication Adherence Using Textile Proximity Sensor)

  • 호종갑;왕창원;민세동
    • 전기학회논문지
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    • 제65권7호
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    • pp.1257-1262
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    • 2016
  • The purpose of this study is to evaluate whether to take a medicine based on a measuring data using textile proximity sensor. We developed a proximity sensor of ring type using conductive textile, and acquired a data in accordance with the quantity of each pills. To evaluate our approach, we designed an experimental protocol that is counting pills subtracting the one which contains range of 0 T(Tablet, 4,100mg) from 20 T. And, The experiments were performed a nine times in the same way. In order to remove a noise and smoothen data, data preprocessing were performed using resampling method and moving average filter which has ten points. Then, we calculated a linear trend line equation, and analyzed a correlation between pill quantity and trend line equation. As a results, correlation coefficient was shown at 0.833 through using a Spearman's correlation method and we could be determined that data was continuos decreases when take a medicine.

직류 마이크로그리드의 전력 공유 정확도 및 전압 제어 성능 향상을 위한 전압 민감도 행렬 기반의 분산 제어 방법 (A Distributed Control Method based on Voltage Sensitivity Matrix in DC Microgrids for Improvement of Power Sharing Accuracy and Voltage Regulation Performance)

  • 이기영;고병선;이재석;김래영
    • 전력전자학회논문지
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    • 제23권5호
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    • pp.345-351
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    • 2018
  • A distributed control method is proposed to improve the power sharing performance of bidirectional distributed generators and the voltage regulation performance of a DC bus in a DC microgrid. Voltage sensitivity analysis based on power flow analysis is conducted to analyze the structural characteristics of a DC microgrid. A distributed control method using a voltage sensitivity matrix is proposed on the basis of this analysis. The proposed method uses information received through the communication system and performs the droop gain variation method and voltage shift method without additional PI controllers. This approach achieves improved power sharing and voltage regulation performance without output transient states. The proposed method is implemented through a laboratory-scaled experimental system consisting of two bidirectional distributed generators, namely, a load and a non-dispatchable distributed generator in a four-bus ring-type model. The experimental results show improved power sharing accuracy and voltage regulation performance.

고무 도뇨관을 이용한 간단한 수지 지혈대 (A Tunable Digital Tourniquet Using Nelaton Catheter)

  • 김상화;임영민;정성노;권호
    • Archives of Plastic Surgery
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    • 제35권6호
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    • pp.759-761
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    • 2008
  • Purpose: Surgery on digit requires a clear, bloodless field and it can be achieved by using a tourniquet. Several type of tourniquet have been used including Penrose drains and sterile glove with hemostat. We present a simple digital tourniquet using nelaton catheter, which is easily available, inexpensive, easy-to-apply, and effective for digital surgery. Methods: We made a small incision on the opposite side of an opening at the tip of nelaton catheter. Then the other tip of nelaton catheter is passed through the incision to form a ring. Nelaton catheter is placed aournd the base of the injured finger, making a tight circle to desired pressure. Results: A simple tourniquet using nelaton catheter effectively achieves a bloodless field and allows fine control of the pressure for digital surgery. Conclusion: We present a sismple digital tourniquet using nelaton catheter, which is easily available, inexpensive, tunable, and available for more than one finger.

Non-contact Transportation of Flat Panel Substrate by Combined Ultrasonic Acoustic Viscous and Aerostatic Forces

  • Isobe, Hiromi;Fushimi, Masaaki;Ootsuka, Masami;Kyusojin, Akira
    • International Journal of Precision Engineering and Manufacturing
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    • 제8권2호
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    • pp.44-48
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    • 2007
  • In recent years, the size of plane substrates and semiconductor wafers has increased. As conventional contact transportation systems composed of, for example, carrier rollers, belt conveyers, and robot hands carry these longer and wider substrates, the increased weight results in increased potential for fracture. A noncontact transportation system is required to solve this problem. We propose a new noncontact transportation system combining acoustic viscous and aerostatic forces to provide damage-free transport. In this system, substrates are supported by aerostatic force and transported by acoustic viscous streaming induced by traveling wave deformation of a disk-type stator. A ring-type piezoelectric transducer bonded on the stator excites vibration. A stator with a high Q piezoelectric transducer can generate traveling vibrations with amplitude of $3.2{\mu}m$. Prior to constructing a carrying road for substrates, we clarified the basic properties of this technique and stator vibration characteristics experimentally. We constructed the experimental equipment using a rotational disk with a 95-mm diameter. Electric power was 70 W at an input voltage of 200 Vpp. A rotational torque of $8.5\times10^{-5}Nm$ was obtained when clearance between the stator and disk was $120{\mu}m$. Finally, we constructed a noncontact transport apparatus for polycrystalline silicon wafers $(150(W)\times150(L)\times0.3(t))$, producing a carrying speed of 59.2 mm/s at a clearance of 0.3 mm between the stator and wafer. The carrying force when four stators acted on the wafer was $2\times10^{-3}N$. Thus, the new noncontact transportation system was demonstrated to be effective.

Chordae Tendineae Approximation Technique for Severe Tricuspid Regurgitation with Severe Leaflet Tethering Using a Totally Endoscopic Beating-Heart Strategy: A Case Report

  • Dong Hee Jang;Jae Suk Yoo
    • Journal of Chest Surgery
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    • 제56권1호
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    • pp.56-58
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    • 2023
  • Untreated severe tricuspid regurgitation (TR) is associated with poor outcomes. Functional TR occurs secondary to dilatation of the annulus and tethering of the leaflets. Ring annuloplasty alone can correct most cases, but is insufficient in cases of severe annular dilatation due to severe leaflet tethering. In such cases, a tricuspid edge-to-edge technique may be an option. However, stitching of the leaflet tips alone is likely to result in tearing of the leaflets. Approximation of the durable chordae tendineae is considered helpful for this problem. Herein, we present the case of a 39-year-old man who had undergone open-heart surgery for acute type A aortic dissection 13 months earlier. A right mini-thoracotomy approach with a beating-heart strategy was used, which did not require unnecessary pericardial adhesiolysis and dissection. This technique had the advantage of reducing the operation time and the risk of bleeding. To summarize, we present a case of tricuspid valve repair in a high-risk patient with severe leaflet tethering that was successfully managed using these methods.

N-Acyliminium에의 친핵성 부가에 의한 Octahydro-2,3-dioxo-cyclopenta[b]pyrrole-3a-carboxylates의 합성 (Synthesis of Octahydro-2,3-dioxo-cyclopenta[b]pyrrole-3a-carboxylates by Nucleophilic Addition to N-Acyliminium)

  • 서원준;정창희;최승주;박영규;김태흥;이상규
    • 대한화학회지
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    • 제38권12호
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    • pp.908-914
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    • 1994
  • 5원자 고리형 ${\beta}$-keto ester와 phenylalkylamine의 탈수축합으로 얻은 enamine A의 oxalyl화 및 물이나 메탄올 부가에 의하여 octahydro-2,3-dioxo-cyclopenta[b]-pyrrole-3a-carboxylate의 6a-hydroxy- 및 6a-methoxy-유도체(1~6)를 합성하였다. 헤테로 고리의 형성은 불안정한 N-acyliminium(B)체를 경유하여 일어나며, 안정한 부가체 C (1∼6)는 endo-ene형 pyrrolinium B에 친핵체를 부가하여 얻을 수 있었다.

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Finite Element Analysis of Reinforced Concrete Shear Walls with a Crack under Cyclic Loading

  • Kato, S.;Ohya, M.;Shimaoka, S.;Takayama, M.
    • Computational Structural Engineering : An International Journal
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    • 제1권2호
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    • pp.107-116
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    • 2001
  • The present paper investigates the nonlinear behavior of reinforced concrete shear walls with a crank based on a finite element analysis. The loading type is a horizontal cyclic one such as earthquake loads. Experiments of the shear walls with and without cranks, performed previously to see flow the behavior changes depending on the crank, are compared with the results obtained from the finite element analysis. The finite element analysis is based on an isoparametric degenerated shell formulation. The nonlinear constitutive equations fur concrete are modeled adopting the formulation based on a concept of Ring Typed-Lattice Model. The experiments indicate that the shear walls with a crank have low stiffness and relatively low carrying capacity compared with an ordinary plane shear wall without cranks and that they are more ductile, and the tendency is a1so confirmed based on the finite element analysis. Moreover, a good agreement between the experiments and analyses is obtained, accordingly, it is confined that the present numerical analysis scheme based on the Lattice Model is a powerful one to evaluate the behavior of reinforced concrete shear walls with cranks and without cranks.

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자가발전형 쿼드콥터 설계 및 제작 (Design and manufacture of a self-powered quadcopter)

  • 이윤성;김윤수
    • 한국항공우주학회지
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    • 제44권5호
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    • pp.431-438
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    • 2016
  • 본 논문은 자가발전형 쿼드콥터를 설계하고 제작한 내용을 다룬다. 본 논문에서 제안하는 자가발전형 쿼드콥터는 전자기유도원리를 이용해 설계된 두 가지 발전장치를 통해 추가 전력을 얻는다. 첫 번째 발전장치는 상용 BLDC모터와 프로펠러를 결합해 함께 회전시켜, BLDC모터를 발전기처럼 활용해 전력을 생산하는 장치이다. 두 번째 발전장치는 프로펠러의 회전축에 작은 자석들을 포함한 프레임을 결합해 함께 회전시켜 코일이 감긴 보호링에서 전력을 생산하는 장치이다. 본 발전장치들은 상용 쿼드콥터 프로펠러 하단에 장착되어 실용적인 발전을 할 수 있으리라 기대된다.

DESIGN OF A SINGLE MODE VARIABLE BRIDGE TYPE SPLIT-POWERED CVT WITH AN INNER-SPHERICAL CONTINUOUSLY VARIABLE UNIT

  • Seong, S.H.;Lee, H.W.;Choi, J.H.;Park, N.G.
    • International Journal of Automotive Technology
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    • 제8권6호
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    • pp.799-806
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    • 2007
  • One method for improving the torque capacity of the CVT is to use a split-powered CVT(SPCVT) to reduce the power transmitted into a continuously variable unit(CVU). A variable bridge SPCVT with two planetary gear units(PGUs), which are composed of a sun gear, a ring gear, and carrier and planetary gears, can minimize the power to the CVU. However, a SPCVT with a conventional CVT should possess a dual mode, which would allow the conventional CVT to be used at high speeds and an additional gear train to be used at low speeds. The inner-spherical CVU(ISCVU) with an inner and outer spherical contact mechanism developed in this study can cover the range from low to high speeds. The rated power and the overall speed ratios were 100 kW and $0.09{\sim}0.36$, respectively. Power efficiency was numerically calculated to be over 90% over the speed ratio range of $0.1{\sim}0.29$. The maximum shear stress at the two contact areas of the rotor pairs, the minimum life and the overall size were estimated to be 700 MPa, 276 kh and $350{\times}350{\times}400mm^3$, respectively. This study shows that an ISCVU and a variable bridge type PGU can realize the SPCVT with a single mode for a vehicle.