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국소 진행된 비소세포 폐암에서 복합요법과 단일요법의 비교 (Comparison of Single vs Combined Modality Treatment in Locally Advanced Non-Small Cell Lung Cancer)

  • 김애경;정성수;신경상;박상기;조혜정;이종진;서지원;김주옥;김선영
    • Tuberculosis and Respiratory Diseases
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    • 제42권4호
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    • pp.502-512
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    • 1995
  • 연구배경: 최근까지 국소 진행된 비소세포 폐암의 치료율을 높이려는 여러 노력들이 있어왔지만 향상은 보이지 않는 설정에서 최근의 유도 화학요법 및 다각적 병합요법의 치료결과와 본 병원의 예를 봄으로 반응률 및 치료 성적을 비교하고 생존에 영향을 미치는 제반 요소들과의 상호 관계에 대해 조사하여 보고하는 바이다. 방법: stage III로 진단된 비소세포 폐암환자 총 67 명을 각각의 치료별로 분류하여 화학치료만 받은 군은 A 군이라 칭하였고, 화학 치료및 방사선 치료를 받은 군은 B군, 수술과 화학 치료를 받은 군은 C군, 비 치료군으로는 D군으로 명하여 이들 군간의 반응률 및 치료 성적을 상호 비교하였고 생존에 영향을 미칠 여러 제반요소들과의 상관관계를 알아 보았다. 결과: 1) 화학 치료만 받은 군은 27 명, 화학 치료 및 방사선 치료를 같이 받은 군은 18 명, 수술 및 화학 치료를 받은 군은 15 명, 비 치료군은 7 명으로 각 군간의 나이, 운동능력, 혈액형, 조직학적, 성별, 흡연력의 분포에 있어서 차이가 없었다(p>0.05). 2) 화학 치료만 받은 군과 방사선 치료도 병합하여 받은 군의 총 반응률은 47%으로 A군의 경우가 10%, B군이 11%를 차지하였으며 이들 간에 의미있는 반응율의 차이는 없었다(p=0.97). 3) 나이, 성별, 운동능력, 혈액형, 조직학적 차이, 흡연력의 치아가 반응률에 영향을 미치지는 않았다(p>0.05). 4) 치료별 A, B, C, D 각 군에 따론 생존 기간은 8.6개월, 13.4개월, 19.2개월, 5.4 개월로 의미있는 차이를 보였다(p=0.003). 비치료군보다는 치료군이, 화학 치료로 단독 치료만 받은 군보다는 병합 치료를 받은 군이 오랜 생존 기간을 보였다. 5) 치료시 생존기간에 영향을 미칠 요소라는 운동능력과 진단 당시 임상병기로 나타났으나 그 외 나이, 성별, 혈액형, 조직학적 분류, 흡연력이 의미있는 차이를 가져오지는 않았다. 결론: 국소 진행된 비소세포 폐암환자에서 복합 화학요법을 포함하여 수술 및 방사선 치료와의 병행은 화학요법 단독으로 치료한 군이든지 혹을 비치료군에 비해 월등하게 생존 기간의 향상을 가져옴으로 좋은 적응증을 가진 환자들을 선택하여 효과적인 화학 치료 및 다른 치료법을 병행하여야 할 것으로 사료된다. 하지만 이러한 여러 치료법들이 표준 치료로 정립되기 위해서는 보다 충분한 증례에서 추후연구가 필요하리라 여겨지는 바이다.

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흡연 습관에 따른 폐암 발생의 차이 (The Difference of Lung Cancer Prevalence According to Smoking Habits)

  • 박무석;정재호;정재희;김영삼;김세규;지선하;장준;김성규
    • Tuberculosis and Respiratory Diseases
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    • 제55권3호
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    • pp.267-279
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    • 2003
  • 연구배경 : 흡연과 폐암 발생 사이의 인과관계는 잘 알려진 사실이지만, 흡연 습관 즉 흡연량 및 기간, 흡연을 처음 시작한 나이, 담배 연기의 흡입 정도, 그리고 담배의 종류 등 다양한 요소들이 폐암 발생에 더욱 크게 작용한다고 한다. 그러나 우리나라에서는 이에 대한 연구 특히 일상동안의 흡연으로 흡입된 타르, 니코틴이 폐암 발생에 미치는 영향에 대한 연구는 없는 실정이다. 방 법 : 연세대학교 의과대학 세브란스병원에 내원한 45세에서 75세 사이의 폐암 환자 150명과 나이와 성별을 일치시킨 폐암이 아닌 질병을 가진 환자 300명을 대상으로 흡연 습관에 따른 폐암 발생 및 폐암 조직형의 교차비, 일생동안 흡입한 티르와 니코틴 총량을 설문지를 통해 조사하여 산술적으로 합산하여 흡입 총량에 따른 교차비를 알아보고자 환자-대조군 연구를 시행하였다. 각 담배에 포함된 개피 당 타르, 니코틴 함량을 문헌을 통해 조사하였고, 개개인의 흡연 습관의 차이에 따른 일생동안 흡입된 타르와 니코틴의 함량을 구하였다. 결 과 : 폐암 환자군 150명 중 현재 흡연자가 가장 많았고, 여자들 중에서는 비흡연자가 가장 많았으며, 대조군도 유사하였다. 폐암 환자군의 흡연 습관 중 통계적으로 의미가 있었던 것은 흡연 기관과 총 갑년, 최근 2년간 피운 하루 당 개피 수이었고, 흡연 시작 나이와 필터 없는 담배를 피운 기간은 대조군과 차이가 없었다. 폐암 조직형 중 편평상피세포암과 소세포암은 남자와 현재 흡연자가 가장 많았으며, 선암은 여자와 비흡연자가 가장 많았다. 흡연 습관들 중 Kreyberg I에서는 흡연 시작 나이가 어릴수록, 흡연 기간이 길수록, 총 갑년이 높을수록, 최근 2년간 피운 하루 당 개피수가 많을수록, 필터없는 담배를 피운 기간이 길수록 교차비는 증가하였다. 또한 산술적으로 합산한 일생동안 흡입된 타르와 니코틴의 총량이 높을수록 교차비가 높았다. 그러나 Kreyberg II에서는 각 흡연 습관들의 교차비는 통계적으로 의미가 없었다. 결 론 : 본 연구는 단일 병원에서 조사되었고, 환자의 기억에 의존하는 제한점이 있으나, 흡연 습관이 폐암 발생, 폐암 조직형 등과 상당한 연관이 있는 것으로 조사되었고, 일생동안 흡연 습관의 변화를 타르와 니코틴의 흡입된 총량으로 산술적으로 계산하였다는 의의가 있다. 향후 이에 대한 대규모 연구가 필요할 것으로 생각된다.

설비공학 분야의 최근 연구 동향: 2011년 학회지 논문에 대한 종합적 고찰 (Recent Progress in Air-Conditioning and Refrigeration Research: A Review of Papers Published in the Korean Journal of Air-Conditioning and Refrigeration Engineering in 2011)

  • 한화택;이대영;김서영;최종민;백용규;김수민
    • 설비공학논문집
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    • 제24권6호
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    • pp.521-537
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    • 2012
  • This article reviews the papers published in the Korean Journal of Air-Conditioning and Refrigeration Engineering during 2011. It is intended to understand the status of current research in the areas of heating, cooling, ventilation, sanitation, and indoor environments of buildings and plant facilities. Conclusions are as follows. (1) Research trends of thermal and fluid engineering have been surveyed as groups of fluid machinery and fluid flow, thermodynamic cycle, and new and renewable energy. Various topics were presented in the field of fluid machinery and fluid flow. Research issues mainly focused on the rankine cycle in the field of thermodynamic cycle. In the new and renewable energy area, researches were presented on geothermal energy, fuel cell, biogas, reformer, solar water heating system, and metane hydration. (2) Research works on heat transfer area have been reviewed in the categories of heat transfer characteristics, pool boiling and condensing heat transfer, nanofluids and industrial heat exchangers. Researches on heat transfer characteristics included heat transfer above liquid helium surface in a cryostat, methane hydrate formation, heat and mass transfer in a liquid desiccant dehumidifier, thermoelectric air-cooling system, heat transfer in multiple slot impinging jet, and heat transfer enhancement by protrusion-in-dimples. In the area of pool boiling and condensing heat transfer, researches on pool boiling of water in low-fin and turbo-B surfaces, pool boiling of R245a, convective boiling two-phase flow in trapezoidal microchannels, condensing of FC-72 on pin-finned surfaces, and natural circulation vertical evaporator were actively performed. In the area of nanofluids, thermal characteristics of heat pipes using water-based MWCNT nanofluids and the thermal conductivity and viscosity were measured. In the area of industrial heat exchangers, researches on fin-tube heat exchangers for waste gas heat recovery and Chevron type plate heat exchanger were implemented. (3) Refrigeration systems with alternative refrigerants such as $CO_2$, hydrocarbons, and mixed refrigerants were studied. Heating performance improvement of heat pump systems were tried applying supplementary components such as a refrigerant heater or a solar collector. The effects of frost growth were studied on the operation characteristic of refrigeration systems and the energy performance of various defrost methods were evaluated. The current situation of the domestic cold storage facilities was analyzed and the future demand was predicted. (4) In building mechanical system fields, a variety of studies were conducted to achieve effective consumption of heat and maximize efficiency of heat in buildings. Various researches were performed to maximize performance of mechanical devices and optimize the operation of HVAC systems. (5) In the fields of architectural environment and energy, diverse purposes of studies were conducted such as indoor environment, building energy, and renewable energy. In particular, renewable energy and building energy-related researches have mainly been studied as reflecting the global interests. In addition, various researches have been performed for reducing cooling load in a building using spot exhaust air, natural ventilation and energy efficiency systems.

설비공학 분야의 최근 연구 동향 : 2012년 학회지 논문에 대한 종합적 고찰 (Recent Progress in Air-Conditioning and Refrigeration Research : A Review of Papers Published in the Korean Journal of Air-Conditioning and Refrigeration Engineering in 2012)

  • 한화택;이대영;김사량;김현정;최종민;박준석;김수민
    • 설비공학논문집
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    • 제25권6호
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    • pp.346-361
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    • 2013
  • This article reviews the papers published in the Korean Journal of Air-Conditioning and Refrigeration Engineering during 2012. It is intended to understand the status of current research in the areas of heating, cooling, ventilation, sanitation, and indoor environments of buildings and plant facilities. The conclusions are as follows : (1) The research works on thermal and fluid engineering have been reviewed as groups of fluid machinery, pipes and valves, fuel cells and power plants, ground-coupled heat pumps, and general heat and mass transfer systems. Research issues are mainly focused on new and renewable energy systems, such as fuel cells, ocean thermal energy conversion power plants, and ground-coupled heat pump systems. (2) Research works on the heat transfer area have been reviewed in the categories of heat transfer characteristics, pool boiling and condensing heat transfer, and industrial heat exchangers. Researches on heat transfer characteristics included the results for natural convection in a square enclosure with two hot circular cylinders, non-uniform grooved tube considering tube expansion, single-tube annular baffle system, broadcasting LED light with ion wind generator, mechanical property and microstructure of SA213 P92 boiler pipe steel, and flat plate using multiple tripping wires. In the area of pool boiling and condensing heat transfer, researches on the design of a micro-channel heat exchanger for a heat pump, numerical simulation of a heat pump evaporator considering the pressure drop in the distributor and capillary tubes, critical heat flux on a thermoexcel-E enhanced surface, and the performance of a fin-and-tube condenser with non-uniform air distribution and different tube types were actively carried out. In the area of industrial heat exchangers, researches on a plate heat exchanger type dehumidifier, fin-tube heat exchanger, an electric circuit transient analogy model in a vertical closed loop ground heat exchanger, heat transfer characteristics of a double skin window for plant factory, a regenerative heat exchanger depending on its porous structure, and various types of plate heat exchangers were performed. (3) In the field of refrigeration, various studies were executed to improve refrigeration system performance, and to evaluate the applicability of alternative refrigerants and new components. Various topics were presented in the area of refrigeration cycle. Research issues mainly focused on the enhancement of the system performance. In the alternative refrigerant area, studies on CO2, R32/R152a mixture, and R1234yf were performed. Studies on the design and performance analysis of various compressors and evaporator were executed. (4) In building mechanical system research fields, twenty-nine studies were conducted to achieve effective design of mechanical systems, and also to maximize the energy efficiency of buildings. The topics of the studies included heating and cooling, HVAC system, ventilation, renewable energy systems, and lighting systems in buildings. New designs and performance tests using numerical methods and experiments provide useful information and key data, which can improve the energy efficiency of buildings. (5) In the fields of the architectural environment, studies for various purposes, such as indoor environment, building energy, and renewable energy were performed. In particular, building energy-related researches and renewable energy systems have been mainly studied, reflecting interests in global climate change, and efforts to reduce building energy consumption by government and architectural specialists. In addition, many researches have been conducted regarding indoor environments.

공기조화, 냉동 분야의 최근 연구 동향 -2004년 및 2005년 학회지 논문에 대한 종합적 고찰- (Recent Progress in Air Conditioning and Refrigeration Research - A Review of Papers Published in the Korean Journal of Air-Conditioning and Refrigeration Engineering in 2004 and 2005 -)

  • 최영돈;강용태;김내현;김만회;박경근;박병윤;박진철;홍희기
    • 설비공학논문집
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    • 제19권1호
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    • pp.94-131
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    • 2007
  • A review on the papers published in the Korean Journal of Air-Conditioning and Refrigerating Engineering in 2004 and 2005 has been done. Focus has been put on current status of research in the aspect of heating, cooling, air-conditioning, ventilation, sanitation and building environment. The conclusions are as follows. (1) Most of fundamental studies on fluid flow were related with heat transportation of facilities. Drop formation and rivulet flow on solid surfaces were interesting topics related with condensation augmentation. Research on micro environment considering flow, heat, humidity was also interesting for comfortable living environment. It can be extended considering biological aspects. Development of fans and blowers of high performance and low noise were continuing topics. Well developed CFD and flow visualization(PIV, PTV and LDV methods) technologies were widely applied for developing facilities and their systems. (2) The research trends of the previous two yews are surveyed as groups of natural convection, forced convection, electronic cooling, heat transfer enhancement, frosting and defrosting, thermal properties, etc. New research topics introduced include natural convection heat transfer enhancement using nanofluid, supercritical cooling performance or oil miscibility of $CO_2$, enthalpy heat exchanger for heat recovery, heat transfer enhancement in a plate heat exchanger using fluid resonance. (3) The literature for the last two years($2004{\sim}2005$) is reviewed in the areas of heat pump, ice and water storage, cycle analysis and reused energy including geothermal, solar and unused energy). The research on cycle analysis and experiments for $CO_2$ was extensively carried out to replace the Ozone depleting and global warming refrigerants such as HFC and HCFC refrigerants. From the year of 2005, the Gas Engine Heat Pump(GHP) has been paid attention from the viewpoint of the gas cooling application. The heat pipe was focused on the performance improvement by the parametric analysis and the heat recovery applications. The storage systems were studied on the performance enhancement of the storage tank and cost analysis for heating and cooling applications. In the area of unused energy, the hybrid systems were extensively introduced and the life cycle cost analysis(LCCA) for the unused energy systems was also intensively carried out. (4) Recent studies of various refrigeration and air-conditioning systems have focused on the system performance and efficiency enhancement. Heat transfer characteristics during evaporation and condensation are investigated for several tube shapes and of alternative refrigerants including carbon dioxide. Efficiency of various compressors and expansion devices are also dealt with for better modeling and, in particular, performance improvement. Thermoelectric module and cooling systems are analyzed theoretically and experimentally. (5) According to the review of recent studies on ventilation systems, an appropriate ventilation systems including machenical and natural are required to satisfied the level of IAQ. Also, an recent studies on air-conditioning and absorption refrigeration systems, it has mainly focused on distribution and dehumidification of indoor air to improve the performance were carried out. (6) Based on a review of recent studies on indoor environment and building service systems, it is noticed that research issues have mainly focused on optimal thermal comfort, improvement of indoor air Quality and many innovative systems such as air-barrier type perimeter-less system with UFAC, radiant floor heating and cooling system and etc. New approaches are highlighted for improving indoor environmental condition as well as minimizing energy consumption, various activities of building control and operation strategy and energy performance analysis for economic evaluation.

볏짚을 이용(利用)한 청국장 제조(製造)에 관(關)한 연구(硏究) (Chungkook-jang Koji Fermentation with Rice Straw)

  • 김경자;류명기;김상순
    • 한국식품과학회지
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    • 제14권4호
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    • pp.301-308
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    • 1982
  • 볏짚을 이용한 재래식 청국장을 $40^{\circ}C$(A구) 및 $50^{\circ}C$(B구)에서 발효시키고, 일반성분, pH 및 적정산도, 질소화합물, protease의 역가 및 유리아미노산의 변화를 분석한 결과는 다음과 같다. 1. 청국장 Koji 발효중의 품온의 변화는 발효온도에 따라 A, B 시험구 모두 상이하였으나 발효시간이 경과함에 따라 상승하였다가 그후 감소하였다. 2. 수분과 조단백질 함량은 모두 발효시간의 경과에 따른 변화가 없었으며 시험구 사이에도 큰 변화를 보이지 않았다. 3. 발효과정중의 pH는 초기 6.4에서 발효 72시간후 pH는 A구가 7.46, B구가 7.82로서 완만하게 증가하였다. 4. 청국장 Koji 발효과정중의 아미노태 질소 및 수용성질소 함량은 모두 증가 현상을 보였으며, 아미노태 질소함량은 숙성후기(60)시간에는 다소 감소하였다. 5 청국장의 조지방 성분은 큰 변화를 보이지 않았으며, 조섬유함량은 완만한 증가현상을 보였다. 6. 청국장 Koji 발효과정중 protease의 역가는 발효 48시간까지는 증가하여 최고에 달하였다가 이후 감소하였다. 7. 청국장 제조과정중 유리아미노산의 함량은 증자직후에는 2.7%이였으나 발효시간이 경과할수록 증가하였으며, 발효 $40^{\circ}C$에서 72시간 숙성시킨 것이(16.2%) $50^{\circ}C$ 시험구(6.9%)보다 유리아미노산의 함량이 현저히 증가하였으며 발효시킨 양시료 중의 유리아미노산의 함량중 glutamic acid가 가장 많았으며 cysteine이 가장 적었다. 8. 이상의 결과를 종합하면 청국장의 최적발효조건은 $40^{\circ}C$에서 72시간이었다. 비교를 통한 치료 선량의 정확성을 평가하고, 방사선 치료의 원활하고 정확한 수행을 위해 실용적이고, 보편적인 치료계획 시스템의 정도관리 방법과 절차서를 수립하는데에 유용할 것으로 사료된다.와 모양에 따라 선택할 수 있도록 하였다. 라디오파를 이용한 온열분포의 측정은 인체조직과 전기적 특성이 비슷한 물질인 한천 팬텀 제작하여 사용하였으며 온도분포 측정은 열전대와 서머그람으로 시행하였다. 생체조직 내에서의 온도분포와 온열효과를 관찰하기 위하여 직접 개의 뇌를 이용하여 시행하였으며 4 개의 전극을 이용하여 43$^{\circ}C$로 50분간 가열하고 일주일후 개를 회생시켜 개 뇌에 대한 조직학적 검사를 시행하였다. 한편 팬텀 표면에서 중앙부로 안테나 길이가 2 cm 인 4 개의 전극을 1 cm 간격으로 정사각형이 되도록 삽입하여 가열하였을 때 90% 등온곡선이 반경 1.25의 원형으로 균일하게 분포되었고 종단면상 삽입관의 길이에 따라 균일한 온도분포가 이루어졌다. 전극을 2 cm 간격으로 삽일 하였을 때 90% 등온곡선이 1.75 반경으로 거의 4 각형의 균일한 분포를 얻었으나 전극의 간격이 증가하면 전도율이 떨어져서 전극 중심부에 불균일한 온도분포를 형성하였다. 동물실험에서 정상 개의 뇌 실질에 자입하여 직접 정방형의 중심을 43$^{\circ}C$로 유지하며 50분간 온열 요법을 시행한 후 관찰한 조직병리학적 소견은 liquefactive necrosis, pyknosis of neuronal element 및 polymorphonuclear leukocytes들의 회백질에서 급성기에 관찰되었고 liquefactive necrosis 주위에 lipid-laden macrophage들이 관찰됨이 공통적인 특정이었으며 후기변화로

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지역사회간호학 관련 논문 연구동향 분석 -학회지 발표 논문을 중심으로- (A Trend of Research in Community Health Nursing)

  • 이인숙;김윤아;최경원;진영란
    • 지역사회간호학회지
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    • 제12권1호
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    • pp.288-298
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    • 2001
  • This article makes an attempt to evaluate the extent of developing community health nursing knowledge and to suggest the direction of developing a body of knowledge henceforth through the results of analysis for contents and outcomes of all literatures. which have been published in the Journal related to community health nursing. Refer to the following for the result of this article. 1. The total number of literatures analyzed amounted to 100 pieces in Journal of community health nursing society. 78 in Journal of industrial nursing society, 134 in Journal of school health society. 40 in Journal of home care nursing society. 2. Journal of community health nursing society Health needs and educational-behavioral diagnoses, which are more concrete nursing assessments and diagnoses. formed the main current(54%) of articles published in Journal of community health nursing society since 1992. There was a quantitative growth as well as a qualitative advance. Through a classification by the type of a body of knowledge. It was found that the knowledge providing nursing practice with bases, commanded an overwhelming majority(71.8%). Also, Researches on systemic supports for nursing practice are showing a tendency to increase. 3. Journal of industrial nursing society 52.6% of research papers presented in Journal of industrial nursing society dealt with health problem of workers. assessment of risk factors, diagnosis of health behaviors. Because of the beginning of an industrial nursing, the domain of nursing management to establish the role and task, work condition, training. documentary system made up 23 percent of research, subjects. A knowledge providing nursing practice with bases have a majority, 69.2%. In addition. the subject concerning a systemic support and quality assurance was scarce but continuously presented. 4. Journal of school health society The major point of this journal is the identification of health problems and risk factors which belong to assessment and diagnosis domain(56.8%) regardless of year, Because of the interdisciplinary characteristic. The knowledge on quality assurance of nursing practice is relatively rare. But, articles related to a systemic support is plentiful. 5. Journal of home care nursing society In its infancy, there was a large number of papers concerning need assessment and diagnosis, Comparing others, this journal has introduced a good many of articles related to program management. delivery system. service fee, etc that belong to domain of systemic support for nursing practice. 6. It is showing definitely that quantity and extent of research have grown for a short period. See the analysis in terms of nursing process, studies related to the domain of assessment and diagnosis command an absolute majority regardless of kinds of journal. Although articles referring to program management and implementation is increasing in number, it is scarce to evaluate a nursing program and grope for an improvement. Also, program development based on a theoretical framework is little. Therefore much more scientific effort to ensure profession should be executed. 7. In the methodological aspect, longitudinal study needs to be carried out so that we could show the evidence based nursing theory. To develop a more general theory, we have to conduct a study of various subjects and improve a validity of tools through a repeat test. In addition, the effort for interdisciplinary cooperation is needed.

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한국인 맞춤형 혈압계 커프 블래더 (Blood Pressure Cuff Bladders Tailored For Koreans)

  • 황락훈;박우성;나승권
    • 한국통신학회논문지
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    • 제38C권9호
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    • pp.822-829
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    • 2013
  • 고혈압은 임상 현장에서 매우 흔한 질환인데 그 유병률이 국제적으로 상승세를 보이고 있다. 고혈압의 폐해는 너무 많으며 여러 장기들에 영향을 미친다. 필요 시 보통 평생 동안 치료해야 한다. 한국질병관리본부에 따르면 고혈압 유병률이 날로 증가하고 있다. 2011 조사에서 성인 중 28.9%가 고혈압이었으며, 여자 보다 남자가 약간 더 높았다. 환자를 분류하고, 혈압관련 위험을 확인하고 그리고 치료법을 안내하는 데 있어 정확한 혈압 측정은 필수적이다. 혈압계의 정확도에 영향을 미치는 요인 중 블래더 크기의 일탈이 장비 에러의 주된 원인이 된다. 혈압을 정확히 측정하기 위해, 위 팔 중심의 둘레에 따른 올바른 크기의 블래더 사용은 필수적이다. 시중의 혈압계를 조사한 결과, 커프 블래더들이 국제 규격 ISO 81060-1:2007에서 권유된 크기와 다름을 알 수 있었다. 블래더가 클 경우 혈압이 더 낮게 나오고, 더 작을 경우 더 높게 나온다는 것은 잘 알려져 있다. 미)심장협회(AHA)가 권고하는 어른용 블래더의 크기는 17-25cm의 팔 둘레를 가진 작은 어른, 24-32 cm의 팔 둘레를 가진 어른, 32-42cm의 팔 둘레를 가진 대다수 어른, 그리고 42-50cm의 팔 둘레를 가진 비만 어른으로 구분 된다. 반면에 한국 어른의 팔 둘레는 23-31cm에 불과하므로 AHA의 어른용 블래더 한 가지에 해당한다. 23-31cm의 팔 둘레를 가진 한국 어른을 위한 블래더의 종류는 ISO 81060-1을 따를 경우 3 개의 블래더가 필요하다. 병원들은 어른 환자들을 위해 보통 하나 혹은 두 가지 크기의 서양식 커프를 사용한다. 이 때문에 일부 환자들은 정확한 혈압 측정을 기대할 수 없다. 한국인에서 취합한 인체치수 참조 데이터에 기초한 블래더의 크기는 한국에서 가장 정확한 혈압을 측정하는데 도움이 될 것이다.

표고 등록균주의 초저온 보존에 관한 연구 (Studies on Cryo-preservation of Registered Strains of Lentinula edodes)

  • 유성열;박원철;구창덕;가강현
    • 한국산림과학회지
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    • 제98권1호
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    • pp.115-124
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    • 2009
  • 새로운 균주가 육종되었을 때 그 균주가 장기간 고유특성을 유지하기란 쉽지 않으며, 시간이 경과 할수록 균주는 퇴화를 거듭한다. 이에 따라 현재 많이 이용되고 있는 초저온에서의 균주보존 후 균사의 활력과 온도가 생존에 미치는 영향과 표고균주가 동결하는 동안 나타나는 상태변화를 이해하고자 하였다. 저온 처리별 균주보존결과 표고균주의 생존은 $-20^{\circ}C$에서 50일간 보존하면 사멸했으며, $-80^{\circ}C$$-196^{\circ}C$에서 보존한 균주들은 온도에 영향을 받지 않고 생존하였다. 저온 처리별 균사생장속도는 $-80^{\circ}C$에서 보존한 균주들의 재생속도가 가장 빨랐다. 균사의 정단부분과 말단부분에 대한 저온 처리별 균주보존 결과 부분별 위치는 균사의 활력과 생존에 영향을 끼치지 못했다. 프로그램이 가능한 동결장치를 이용하여 표고균주의 동결과정에서 나타나는 현상을 조사한 결과 균주별 각기 다른 어는점을 가지고 있었다. 또한 표고의 자실체 발생 온도형과 균주별 어는점과의 관계는 관련이 없었다. 프로그램이 가능한 동결장치를 이용하여 표고균주의 동결과정에서 나타나는 상태변화를 최소화하기 위해 일시적으로 낮은 온도로 동결을 시도하였지만 균주들은 온도에 영향을 받지 않았다.

아동의 심리발달과 도서선호의 변화 (A Study on the Relationship of Children's Development and Book Preference)

  • 한윤옥
    • 한국문헌정보학회지
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    • 제17권
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    • pp.105-159
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    • 1989
  • The purpose of this study is (a) to identify physical and content elements of children's books that seem to interest second and fifth graders to read, and (b) to observe how the influence of those elements on children's reading interest shifts as children develop. For the purpose of this study, children's books are classified into two groups: 'books of low preference' and 'books of high preference' as determined by second graders, and fifth graders' library circulation record in the library chosen as the sample for the present study. The physical and content elements of the books belonging to these two groups are analyzed and compared. Main findings and conclusions made in this study are summarised as follows: (1) The physical elements of children's books which have significant relationship with second graders' reading preference are illustration quantity, size of types, space between lines, and size of the book. (2) The content elements of children's books which have significant relationship with second graders' reading preference are the readability level of sentences, and the sex of heroes. (3) The physical elements of children's books which have significant relationship with fifth graders' reading preference are illustration quantity, illustration styles, and size of the book. (4) The content elements of children's books which have significant relationship with fifth graders' reading preference are the readability level, the sex of heroes, subject matters, themes and the environmental settings as the background of stories. (5) Reading preference of the pupils at the second and fifth grades are influenced by the quantity of illustration. Second grade pupils prefer reading books which contain a larger quantity of illustrations, whereas 5th grade pupils prefer books which contain less quantity of illustrations. (6) The relationship between second graders' reading preference and the illustration style are rejected at the $10\%$ significance level. A strong relationship, however, appears to exist between 5th graders' reading preference and the illustration style. The 5th grade pupils prefer more realistic illustrations, while cartoons and semi-abstract drawings do not appeal to them. (7) The type size, and space between lines which have had great influence on the book preference of 2nd grade pupils influence little on the 5th grade pupils book preference. (8) Second grade pupils prefer the book of a small Size, whereas 5th grade pupils whose reading taste has developed at a primary stage prefer the book of a large size beyond a certain standard. (9) Second grade pupils prefer reading books which can be easily read, whreeas 5th grade pupils prefer reading books containing difficult sentences. (10) Second grade pupils and the 5th grade pupils both prefer books in accordance with the sex of there heroes. (11) Relationship between second graders' reading preference and the subject matters are rejected at the 10% significance level. A strong relationship, however, appears to exist between 5th graders' reading preference and the subject matter. Fifth grade pupils prefer reading books of which the themes are mystery, exploration and adventure. (12) The theme of books is not proved to relate with the book preference of the 2nd grade pupils, but it is closely related with the book preference of 5th grade pupils. Fifth grade pupils prefer reading books which contain exploratory stories. (13) Second grade pupils are not influenced by the environmental setting of the story, but 5th grade pupils prefer reading stories with the environmental setting in the air. (14) The quantity of illustrations is the element influencing most on .the book preference of the 2nd grade pupils, followed by the space between the lines, which influences least on the book preference of the 5th grade pupils. (15) The physical element influencing most on the book preference of the 2nd grade pupils is the quantity of the illustrations. The physical element which has the most strong influence on the book preference of the 5th graders is illustration styles. (16) The content elements which has much influence on the book preference of the 5th grade pupils are certain kinds of characteristics of heroes. In case of the 2nd grade pupils book preference, striking evidence of such characteristics of heroes is not traced.

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