• Title/Summary/Keyword: two-dimensional treatment

Search Result 452, Processing Time 0.023 seconds

The Determination of Optimum Beam Position and Size in Radiation Treatment (방사선치료시 최적의 빔 위치와 크기 결정)

  • 박정훈;서태석;최보영;이형구;신경섭
    • Progress in Medical Physics
    • /
    • v.11 no.1
    • /
    • pp.49-57
    • /
    • 2000
  • New method about the dose optimization problem in radiation treatment was researched. Since all conditions are more complex and there are more relevant variables, the solution of three-dimensional treatment planning is much more complicate than that of current two-dimensional one. There(ore, in this study, as a method to solve three-dimensional dose optimization problem, the considered variables was minized and researched by reducing the domain that solutions can exist and pre-determining the important beam parameters. First, the dangerous beam range that passes critical organ was found by coordinate transformation between linear accelerator coordinate and patient coordinate. And the beam size and rotation angle for rectangular collimator that conform tumor at arbitrary beam position was also determined. As a result, the available beam position could be reduced and the dependency on beam size and rotation angle, that is very important parameter in treatment planning, totally removed. Therefore, the resultant combinations of relevant variables could be greatly reduced and the dose optimization by objective function can be done with minimum variables. From the above results, the dose optimization problem was solved for the two-dimensional radiation treatment planning useful in clinic. The objective function was made by combination of dose gradient, critical organ dose and dose homogeniety. And the optimum variables were determined by applying step search method to objective function. From the dose distributions by optimum variables, the merit of new dose optimization method was verified and it can be implemented on commercial radiation treatment planning system with further research.

  • PDF

Clinical Observation of Three Dimensional Conformal Radiotherapy with Tamoxifen in Treatment of Postoperative Malignant Glioma

  • Zhou, Shao-Bing;Liu, Yang-Chen;Yin, Xiao-Xiang;Ding, Wen-Xiu;Guo, Xin-Wei;Gu, Liang;Huang, Xin-En
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.16 no.5
    • /
    • pp.1743-1745
    • /
    • 2015
  • Objective: To evaluate the efficacy and adverse effects of three dimensional conformal radiotherapy (3D-CRT) with tamoxifen in treating patients with postoperative malignant glioma. Patients and Methods: 60 patients of postoperative malignant glioma were randomly assigned into two groups, 30 patients were treated with 3D-CRT plus tamoxifen (treatment group), and the other 30 patients with 3D-CRT plus temozolomide (control group). All patients were radiated by 6MV X-ray, 2.0Gy per fraction, once daily, with a total dose (DT) of 56~60Gy. Tamoxifen was delivered at $60mg/m^2/d$, temozolomide was given at $75mg/m^2/d$. All patients were treated with concurrent radiotherapy. Results: One, 2, 3 year survival rates of treatment and control group were 63.3%, 30.0%, 23.0% and 70.0%, 33.3%, 26.7%, respectively (${\chi}^2=0.01$, 0.23, 0.09, P>0.05). The rate of thromboembolism in treatment group was 6.7%. Conclusion: Therapeutic efficacy of two groups was similar, but it was more cost-effective in treatment group, and toxicity did not increase.

COMPUTATIONAL STUDY ON TWO DIMENSIONAL DAM BREAKING SIMULATION USING LATTICE BOLTZMANN METHOD (LBM을 이용한 Dam Breaking 수치해석 연구)

  • Jung, Rho-Taek;Hasan, Md. Kamrul
    • 한국전산유체공학회:학술대회논문집
    • /
    • 2011.05a
    • /
    • pp.54-57
    • /
    • 2011
  • In this paper we present an algorithm about how to simulate two dimensional dam breaking with lattice Boltzmann method (LBM). LBM considers a typical volume element of fluid to be composed of a collection of particles that represented by a particle velocity distribution function for each fluid component at each grid point. We use the modified Lattice Boltzmann Method for incompressible fluid. This paper will represent detailed information on single phase flow which considers only the water instead of both air and water. Interface treatment and conservation of mass are the most important things in simulating free surface where the Interface is treated by mass exchange with the water region. We consider the surface tension on the interface and also bounce back boundary condition for the treatment of solid obstacles. We will compare the results of the simulation with some methods and experimental results.

  • PDF

Use of cone-beam computed tomography and three-dimensional modeling for assessment of anomalous pulp canal configuration: a case report

  • Sinanoglu, Alper;Helvacioglu-Yigit, Dilek;Mutlu, Ibrahim
    • Restorative Dentistry and Endodontics
    • /
    • v.40 no.2
    • /
    • pp.161-165
    • /
    • 2015
  • Three-dimensional (3D) reconstruction of cone-beam computed tomography (CBCT) scans appears to be a valuable method for assessing pulp canal configuration. The aim of this report is to describe endodontic treatment of a mandibular second premolar with aberrant pulp canal morphology detected by CBCT and confirmed by 3D modeling. An accessory canal was suspected during endodontic treatment of the mandibular left second premolar in a 21 year old woman with a chief complaint of pulsating pain. Axial cross-sectional CBCT scans revealed that the pulp canal divided into mesiobuccal, lingual, and buccal canals in the middle third and ended as four separate foramina. 3D modeling confirmed the anomalous configuration of the fused root with a deep lingual groove. Endodontic treatment of the tooth was completed in two appointments. The root canals were obturated using lateral compaction of gutta-percha and root canal sealer. The tooth remained asymptomatic and did not develop periapical pathology until 12 months postoperatively. CBCT and 3D modeling enable preoperative evaluation of aberrant root canal systems and facilitate endodontic treatment.

Dosimetric Characteristic of Digital CCD Video Camera for Radiation Therapy

  • Young Woo. Vahc;Kim, Tae Hong.;Won Kyun. Chung;Ohyun Kwon;Park, Kyung Ran.;Lee, Yong Ha.
    • Progress in Medical Physics
    • /
    • v.11 no.2
    • /
    • pp.147-155
    • /
    • 2000
  • Patient dose verification is one of the most important parts in quality assurance of the treatment delivery for radiation therapy. The dose distributions may be meaningfully improved by modulating two dimensional intensity profile of the individual high energy radiation beams In this study, a new method is presented for the pre-treatment dosimetric verification of these two dimensional distributions of beam intensity by means of a charge coupled device video camera-based fluoroscopic device (henceforth called as CCD-VCFD) as a radiation detecter with a custom-made software for dose calculation from fluorescence signals. This system of dosimeter (CCD-VCFD) could reproduce three dimensional (3D) relative dose distribution from the digitized fluoroscopic signals for small (1.0$\times$1.0 cm$^2$ square, ø 1.0 cm circular ) and large (30$\times$30cm$^2$) field sizes used in intensity modulated radiation therapy (IMRT). For the small beam sizes of photon and electron, the calculations are performed In absolute beam fluence profiles which are usually used for calculation of the patient dose distribution. The good linearity with respect to the absorbed dose, independence of dose rate, and three dimensional profiles of small beams using the CCD-VCFD were demonstrated by relative measurements in high energy Photon (15 MV) and electron (9 MeV) beams. These measurements of beam profiles with CCD-VCFD show good agreement with those with other dosimeters such as utramicro-cylindrical (UC) ionization chamber and radiographic film. The study of the radiation dosimetric technique using CCD-VCFD may provide a fast and accurate pre-treatment verification tool for the small beam used in stereotactic radiosurgery (SRS) and can be used for verification of dose distribution from dynamic multi-leaf collimation system (DMLC).

  • PDF

THE STUDY OF ARCH DIMENSIONAL CHANGES BEFORE AND AFTER ORTHODONTIC TREATMENT IN ANGLE CLASS I MALOCCLUSION CASES (Angle씨 I급 부정교합 환자에서 교정치료 전, 후의 악궁크기 변화에 관한 연구)

  • Jeong, Mi;Ryu, Young Kyu
    • The korean journal of orthodontics
    • /
    • v.20 no.1
    • /
    • pp.183-195
    • /
    • 1990
  • The purposes of present study were to identify possible relationships between post-treatment changes and post-retention changes. The patient's models were composed of 58 samples, and were classified non-extraction group (30 samples) and extraction group (28 samples). For each sample the first models were taken prior to the start of treatment, the second models just after the end of treatment, and the third models two years after. The results were as follows: 1. In the cases of non-extraction group, increases were in intermolar width of maxilla, interbicuspid width of maxilla and arch perimeter of mandible during treatment period, but decreases were in the same measurements during post-retention period. 2. In the cases of extraction group, decreases were in intermolar width of mandible, interbicuspid widths of maxilla and mandible, arch length of mandible, arch perimeters of maxilla and mandible during treatment period. 3. Significant decreases were in the irregularity index of both extraction and non-extraction group during treatment period. 4. There were significant differences of arch dimensional changes in intermolar widths of maxilla and mandible, interbicuspid widths of maxilla and mandible, arch lengths of maxilla and mandible, arch perimeters of maxilla and mandible between non-extraction and extraction group.

  • PDF

A Comparative Study of PISO, SIMPLE, SIMPLE-C Algorithms in 3-dimensional Generalized Coordinate Systems (3차원 일반 좌표계에서의 PISO, SIMPLE, SIMPLE-C 알고리즘의 비교)

  • Park J. Y.;Baek J. H.
    • Journal of computational fluids engineering
    • /
    • v.1 no.1
    • /
    • pp.26-34
    • /
    • 1996
  • The performance of the SIMPLE, SIMPLE-C and PISO algorithms for the treatment of the pressure-velocity coupling in fluid flow problems were examined by comparing the computational effort required to obtain the same level of the convergence. Example problems are circular duct and 90-degree bent square-duct. For circular duct case, laminar and turbulent flow were computed. For 90-degree bent square-duct case, laminar flow was simulated by the time-marching method as well as the iterative method. The convergence speed of the other two algorithms are not always superior to SIMPLE algorithm. SIMPLE algorithm is faster than SIMPLE-C algorithm in the simple laminar flow calculations. The application of the PISO algorithm in three dimensional general coordinates is not so effective as in two-dimensional ones. Since computational time of PISO algorithm is increased at each time step(or iterative step) in three dimension, the total convergence speed is not decreased. But PISO algorithm is stable for large time step by using time marching method,.

  • PDF

Retrospective analysis of intensity-modulated radiotherapy and three-dimensional conformal radiotherapy of postoperative treatment for biliary tract cancer

  • Lee, Hyo Chun;Lee, Jong Hoon;Lee, Sea-Won;Lee, Joo Hwan;Yu, Mina;Jang, Hong Seok;Kim, Sung Hwan
    • Radiation Oncology Journal
    • /
    • v.37 no.4
    • /
    • pp.279-285
    • /
    • 2019
  • Purpose: This study was conducted to compare the outcome of three-dimensional conformal radiotherapy (3D-CRT) and intensity-modulated radiotherapy (IMRT) for the postoperative treatment of biliary tract cancer. Materials and Methods: From February 2008 to June 2016, 57 patients of biliary tract cancer treated with curative surgery followed by postoperative 3D-CRT (n = 27) or IMRT (n = 30) were retrospectively enrolled. Results: Median follow-up time was 23.6 months (range, 5.2 to 97.6 months) for all patients and 38.4 months (range, 27.0 to 89.2 months) for survivors. Two-year recurrence-free survival is higher in IMRT arm than 3D-CRT arm with a marginal significance (25.9% vs. 47.4%; p = 0.088). Locoregional recurrence-free survival (64.3% vs. 81.7%; p = 0.122) and distant metastasis-free survival (40.3% vs. 55.8%; p = 0.234) at two years did not show any statistical difference between two radiation modalities. In the multivariate analysis, extrahepatic cholangiocarcinoma, poorly-differentiated histologic grade, and higher stage were significant poor prognostic factors for survival. Severe treatment-related toxicity was not significantly different between two arms. Conclusions: IMRT showed comparable results with 3D-CRT in terms of recurrence, and survival, and radiotherapy toxicity for the postoperative treatment of biliary tract cancer.

A Study on a Comparative Analysis of 2D and 3D Planning Using CT Simulator for Transbronchial Brachytherapy (전산화단층모의치료기를 이용한 경기관지 근접치료환자의 치료계획에 관한 고찰)

  • Seo, Dong Rin;Kim, Dae Sup;Back, Geum Mun
    • The Journal of Korean Society for Radiation Therapy
    • /
    • v.25 no.1
    • /
    • pp.69-75
    • /
    • 2013
  • Purpose: Transbronchial brachytherapy used in the two-dimensional treatment planning difficult to identify the location of the tumor in the affected area to determine the process analysis. In this study, we have done a comparative analysis for the patient's treatment planning using a CT simulator. Materials and Methods: The analysis was performed by the patients who visited the hospital to June 2012. The patient carried out CT-image by CT simulator, and we were plan to compare with a two-dimensional and threedimensional treatment planning using a Oncentra Brachy planning system (Nucletron, Netherland). Results: The location of the catheter was confirmed the each time on a treatment planning for fractionated transbronchial brachytherapy. GTV volumes were $3.5cm^3$ and $3.3cm^3$. Also easy to determine the dose distribution of the tumor, the errors of a dose delivery were confirmed dose distribution of the prescibed dose for GTV. In the first treatment was 92% and the second was 88%. Conclusion: In order to compensate for the problem through a two-dimensional treatment planning, it is necessary to be tested process for the accurate identification and analysis of the treatment volume and dose distribution. Quantitatively determine the dose delivery error process that is reflected to the treatment planning is required.

  • PDF

Three-dimensional evaluation of the correlation between lip canting and craniofacial planes

  • Kim, Jun-Young;Park, Hee-Keun;Shin, Seung-Woo;Park, Jin Hoo;Jung, Hwi-Dong;Jung, Young-Soo
    • The korean journal of orthodontics
    • /
    • v.50 no.4
    • /
    • pp.258-267
    • /
    • 2020
  • Objective: This study aimed to analyze the correlation of horizontal and sagittal planes used in two-dimensional diagnosis with lip canting by using three-dimensional (3D) analysis. Methods: Fifty-two patients (25 men, 27 women; average age: 24 years) undergoing treatment for dentofacial deformity were enrolled. Computed tomography images were acquired, and digital imaging and communication in medicine files were reconstructed into a 3D virtual model wherein horizontal and sagittal craniofacial planes were measured. Subsequently, the correlations of lip canting with these horizontal and sagittal planes were investigated. Results: The mandibular symmetry plane, the occlusal plane, Camper's plane, the mandibular plane, Broadbent's plane, and the nasal axis plane were correlated with the amount of lip canting (Pearson's correlation coefficients: 0.761, 0.648, 0.556, 0.526, 0.438, and 0.406, respectively). Planes associated with the lower part of the face showed the strongest correlations; the strength of the correlations decreased in the midfacial and cranial regions. None of the planes showed statistically significant differences between patients with clinical lip canting (> 3°) and those without prominent lip canting. Conclusions: The findings of this study suggest that lip canting is strongly correlated with the mandibular symmetry plane, which includes menton deviation. This finding may have clinical implications with regard to the treatment of patients requiring correction of lip canting. Further studies are necessary for evaluating changes in lip canting after orthognathic surgery.