• 한국ITS학회:학술대회논문집
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• 한국ITS학회 2006년도 제5회 추계학술대회 및 정기총회
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• pp.18-24
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• 2006

• Journal of the Korean Data and Information Science Society
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• 제22권4호
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• pp.631-641
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• 2011

과거 시행의 승패 결과에 의해 현재 시행의 승패 확률이 결정되는 과거 의존 파론도 게임을 고려한다. 여러 명의 게임자들이 과거 의존 파론도 게임을 구성하는 공정한 두 게임 중에서 한 게임을 임의로 선택하는 전략과 매 시행 때마다 현재의 상태를 이용하여 그 기대상금이 최대인 게임을 선택하는 전략을 비교한다. 현재의 상태를 고려하지 않고 임의적으로 게임을 선택하는 전략은 점차 기대상금이 양수가 되어 결국 이기는 게임이 되는 반면에 현재의 상태를 이용하여 최적의 게임을 선택하는 전략은 게임이 진행될수록 오히려 기대상금이 0으로 일정하게 되는 역설적인 현상이 나타남을 확인하고, 이러한 역설적인 현상이 발생하는 확률 모수의 범위를 찾는다.

• BMB Reports
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• 제43권6호
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• pp.407-412
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• 2010

Homeodomain (HD) is a highly conserved DNA-binding domain composed of helix-turn-helix motif. Drosophila Vnd (Ventral nervous system defective) containing HD acts as a regulator to either enhance or suppress gene expression upon binding to its target sequence. In this study, kinetic analysis of Vnd binding to DNA was performed. The result demonstrates that DNA-binding affinity of the recombinant protein containing HD and NK2-specific domain (NK2-SD) was higher than that of the full-length Vnd. To access whether phosphorylation sites within HD and NK2-SD affect the interaction of the protein with the target sequence, alanine substitutions were introduced. The result shows that S631A mutation within NK2-SD does not contribute significantly to the DNA-binding affinity. However, S571A and T600A mutations within HD showed lower affinity for DNA binding. In addition, DNA-binding analysis using embryonic nuclear protein also demonstrates that Vnd interacts with other nuclear proteins, suggesting the existence of Vnd as a complex.

• BMB Reports
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• 제36권6호
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• pp.552-557
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• 2003

Oligomers with $\alpha$-aminooxy acids are reported to form very stable turn and helix structures, and they are supposed to be useful peptidomimetics for drug design. A recent report suggested that homochiral oxa-peptides form a strong eight-member-ring structure by a hydrogen bond between adjacent aminooxy-acid residues in a $CDCl_3$ solution. In order to design an $\alpha$-MSH analog with a stable turn conformation, we synthesized four tetramers and one pentamer, based on $\alpha$-MSH sequence, and determined the solution structures of the molecules by two-dimensional NMR spectroscopy and simulated annealing calculations. The solution conformations of the three peptidomimetic molecules (TLV, TDV, and TLL) in DMSO-$d_6$ contain a stable 7-membered-ring structure that is similar to a $\gamma$-turn in normal peptides. Newly-designed tetramer TDF and pentamer PDF have a ball-type rigid structure that is induced by strong hydrogen bonds between adjacent amide protons and carbonyl oxygens. In conclusion, the aminooxy acids, easily prepared from natural or unnatural amino acids, can be employed to prepare peptidomimetic analogues with well-defined turn structures for pharmaceutical interest.

• 복식
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• 제50권7호
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• pp.219-233
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• 2000

This paper is designed to suggest marketing strategies suitable for each classified group by subdividing high school students, the new-generation consumers, by clothes-shopping orientation at jean markets and by identifying the demographic characteristics and the purchasing behavior of each classified group. The subjects consist of 644 high school students. female and male, in Seoul, who responded to my questionnaire research. In terms of the clothes-shopping orientation, pleasure shopping orientation, brand-based shopping orientation, fashion-oriented one, convenience-oriented one and economic one are in sequence. In light of the consumer group based on the factors of clothes-shopping tendencies, the convenience-oriented group ranks first, which is followed by pleasure shopping group, brand-based shopping group and economic one. The subjects turn out to have purchased jeans at time of necessity, The subjects are most liable to get information from their friends, which is followed by their shopping experiences and display. And they turn out to be little affected by family members, salespersons and the press. They regarded aesthetic standards as one of the most important standards, which are followed by size, fitting, personality expression and prices in order. On the other hand, they think little of such factors as friends and similarity. In terms of the standards to make a selection of shops, the respondents cite the quality of goods, the prices of jeans, and service. They didn't think much of the importance of the persuasion of those around them, the convenience of mass transportation facilities, and the approving rate of brands and so on. They resort to wholesale markets, department stores and low-pricing shops in sequence. They turn out not to be satisfied with product guarantees, and fashion. They relied on aggressive approaches like exchanges and refund in case they were dissatisfied with jeans.

• 한국보건간호학회지
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• 제10권1호
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• pp.118-138
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• 1996

Because of accelerated urbanization public body visiting nursing project that started according as matter of health on urban class in the lower brackets of income was concentrated on Social interests has a unsatisfied points to propel project efficiently from the lack of rating materials. Therefore centering around written contents in documentary literature of citizen health by household in five years from starting year of project to now. visiting frequency by medical manpower was evaluated quantitatively and qualitatively in aspect of management hereupon. for the sake of giving a basic materials for public health project of this field. This research presents documentary literature of citizen health which become materials is that as one person's charged region of nurse in duty scale. district is Kang-Buck Gu. the object is resident in the lower brackets of income grounded livelihood protection law and who is admitted by the head of organ~chief of health care). and the number of material centering around the head of a household is 415 copy. The result of research is summarized. as follow. 1. Average visiting frequency examinated by medical manpower show difference according to valuables of supervision characteristics namely average visiting. Frequency of nurse has long term residence in case registration season is early and supervision season is the first year and is high incase a kind of house is unlicdnsed mountain town. Average visiting frequency with doctor is high incase supervision season is the first year and the medical insurance system is admitted by chief of health care. That shows that a man of discomfort behavior left alone are yet many in local society. The meaning of this result shows that the continuity of official relation about class in the lowest brackets of income of long term residence goes well between househole who is a user of visiting nursing service of the object according to midway income under management influences a given duty of nurse s and so causes quantitative decrease. 2. In case behavier and condition of health that nurse diagnoses are bad. as the type matter is a lack of health and the number of patient is large. the average visiting frequency of nurse is high. because average visiting frequency with doctor is high as the condition of health is bad and the number of patient is large. That is similar with that of nurse. CD Average visiting frequency of nurse s seen by matter of disease is very high only in apoplexy by 39.50 and is confined within limits from 7.63 to 11.36 in other disease. But average visiting frequency with doctor is double as many as that of nurse but defined in apoplexy hypertension and articulate. (1) Average visiting frequency of nurse by existence in inoculation of hepatitis is low by 6.73 in unidentified group and very high by 26.89 in group of non-inoculation and the case of the antigenic positive man of B type hepatitis or epileptic who can't be inoculated shows 13.00 and that even family nursing service is needed to them. That result shows that though one person nurse of local charge has a large scale of duty. as visting nursing service is given a class who has a large demand preferentially by respectively accurate nursing diagnosis. the number of diagnosis service is similar with it. 3. During five years. average visiting frequency of nurse is 10.84 and average visiting frequency with doctor is 76.50 seeing from the official scale of nurse. visiting by household is performed two more per year to the average. Seeing this by type of service. average visiting frequency of nurse is higher in indirectly nursing than in directly nursing and that suggests that at the time of visiting household nurse performs education of protection lively save patient but at the time of contrastedly visiting with doctor. directly nursing is more contents of service show no difference by man power and medication dressing by demand is 14.3 and 18.6 the aid of hardship term of doctor and nurse is high by 18.7 and 17.00 in the request of hospitalization when seeing by demands. 4. Action by turns exemplified 1994 is well in sequence of 2/4 turn. 3/4 turn. 1/4 turn. 4/4 turn. When seen by average visiting frequency of nurse but gradually is even. Without difference by turns. average visiting frequency of doctor is much higher in 1/4 turn than other turns. Type of service by turns is all even but directly nursing is inactive in 4/4 and indirectly nursing. Very increases in 4/4 and so. Nurse's quantity of duty is plentiful that shows that by evaluation of last turn and plan of project. Contents of service follows that medication and dressing is the highest by' 5.57 in 1/4turn. goes down gradually by turn. becomes 3.57 in 3/4 turn. and increases again by 4.83 in 4/4 turn. the rest service is higher in 2/4 turn than other turns. 5. Total visiting frequency of nurse is explained to total $37.5\%$ by six valuables of visiting frequency of doctor. nursing demand. demand of diagnosis. condition of behavior. year. Special terms and magnitude of influential power is the same as sequence of enumerated valuables. Namely. the higher the visiting frequency of doctor. the bigger nursing and demand of diagnosis is. the worse the condition of behavior is. the older the object is and the more the household of special terms is. the high total visiting frequency of nurse is.

• Reproductive and Developmental Biology
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• 제29권1호
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• pp.57-62
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• 2005

본 연구에서는 retrovirus를 이용한 유전자 전이에 있어서 대두되는 큰 문제점의 하나인 외래 유전자의 지속적인 발현으로 인한 개체의 생리적인 손상을 최소화하기 위하여 tetracycline계 물질의 공급 여부에 따라서 발현을 유도적으로 조절할 수 있는 one vector 형태의 Tet-On system을 구축하고자 하였다. 또한 WPRE 서열을 이 vector 상에 도입하여 유도적 조건에서 외래 유전자의 발현이 보다 강하게 일어날 수 있는 효율적인 retrovirus vector system을 확립하고자 하였다. 구축한 각각의 vector system에서 fluorometry와 western blotting을 이용하여 GFP 유전자의 발현 정도를 비교 측정한 결과, RevTRE-EGFP-WPRE-RSVp-rtTA2SM2 virus를 이용하여 유전자를 전이시킨 표적세포에서 GFP의 절대적인 발현량이 가장 큰 것으로 나타났고, 유전자 발현의 turn on/off에 의한 유도율은 RevTRE-EGFP-RSVp-rtTA2SM2-WPRE virus의 경우에서 8∼21배로 가장 높은 것으로 나타났다. 이상의 결과에서 외래 유전자의 발현을 효율적으로 조절할 수 있는 vector system은 WPRE가 rtTA2SM2 서열의 3에 위치한 형태로, 이 system을 이용하여 생산한 고감염가의 virus는 유전자 치료나 형질전환 동물의 생산에 있어서 요구되는 외래 유전자의 발현을 효율적으로 조절할 수 있는 수단이 될 것이다.

• 한국제4기학회지
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• 제18권2호통권23호
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• pp.33-42
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• 2004

In South Korea a Pedo-sedimentary Sequence(PS) indicating the Last Glacial Maximun(LGM) is typified y a brown to dark brown, relatively stiff paleosol layers formed by repetitive freezing and thawing processes which in turn left characteristi glossic textures in soil-solum, polygolnal structures with a flagipans, vertical soil wedges or freezing cracks, and horizontal foliations, As a pre-LGM sedimentary sequences (older than 25Ka), the Old Fluvial Sequence(OFS) overlain by the Slope Sedimentary Sequence(SS) are distributed commonly at the base level higher than 14-15m above present river-bed along the major river basin. After the LGM (ca. 18Ka), the Young Fluvial Sequence(YFS) appears at an altitude ascending order of sedimentary profiles. In this fluvial organic muds of Jangheungri site(Jinju), Sorori site(Cheonwon), and Youngsan estruarine rivermouth(Mokpo) were exemplified in order to interpret their formation ages and environments. As result of $^{14}C$ datings, the formation ages of te organic muds are Boelling to Alleroed (MIS-1). These organic muds were fomed in fluvial backswamp or local pond/bog in response to shifting fluvial system. On the basis of palynological production dominant with Abies/Picea-Betula and Ranunculaceae, Compositae, Cyperaceae, and Graminae, it was interpreted that more boreal to subboreal condition was prevailed rather than temperate like today during the formation of organic muds and soil moisture condition was a repetition of wet and dry condition.

• 한국석유지질학회:학술대회논문집
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• 한국석유지질학회 2000년도 제7차 학술발표회 발표논문집
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• pp.14-30
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• 2000

Hierarchically controlled sequence stratigraphic analysis shows that the Lower Ordovician mixed carbonate-siliciclastic Mungok Formation, Korea consists of three depositional sequences: T1, T2, and T3. Sequence boundaries are generally marked by abrupt transition from coarse-grained shallow-water carbonates to fine-grained deeper-water carbonates mixed with fine-grained siliciclastics, and show indication of subaerial exposure such as karstification. Within this sequence stratigraphic framework, facies characteristics indicate that the Mungok sequences were mostly deposited in subtidal ramp environments. High-frequency cycles consist of upward-shallowing facies successions. Cycles of shallow-water and basinal deposits are not represented well, probably due to cycle amalgamation. Cycle stacking patterns do not show a consistent thickness change that reflects a large-scale sea-level change due to unfilled accommodation space. The Mungok sequences show that many factors including relative sea-level change and topography are involved in controlling sequence development on carbonate ramps. The depositional setting evolved from the high-energy ramps in the sequences T1 and T2 into the low-energy ramp in the sequence T3. Topography is interpreted to have been responsible for the different energy regimes of the carbonate ramps in the Mungok sequences. The high ramp gradient in the sequences T1 and T2 seems to be caused by space-time-dissociated differential sedimentation resulting in spatially narrow distribution of sediment filling, which in turn may be related to high rate of relative sea-level change. In contrast, low ramp gradient was maintained in the sequence T3 during slow changes of relative sea level resulting in broad distribution of sediment filling.

• 천문학회보
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• 제40권2호
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• pp.58.3-58.3
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• 2015

Blue Straggler Stars (BSSs), kind of unusual main sequence stars, are the brighter and bluer stars than the main sequence turn off (MSTS) stars in coeval clusters. Since the first detection in globular clusters (GCs), BSSs have been shown to reveal an anti-correlation between the luminosity of their host star cluster and the number of BSSs in the cluster. Further, conclusions based on this result can be expanded to the open clusters. BSSs seem to play an important role in GCs according to the relation between the dynamical time scale of GCs and the number of BSSs along the cluster radius. This relation, however, remains to be verified in open clusters, In this study, we divide open clusters by the existence of BSSs into two groups. Then we compare parameters between these groups to specify the role of BSSs in open clusters.