• Journal of Society of Preventive Korean Medicine
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• v.19 no.1
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• pp.61-70
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• 2015

Objective : The aim of this study is to investigate the features of clinical trial which used symptom differentiation on cancer patients Method : Electronic databases including Ovid-Medline, Ovid-EMBASE, and Cochrane library were searched. Search terms incorporating the concepts of cancer, herbal medicine, clinical trial were used. Articles described using symptom differentiation in methods were selected. Results : Twelve studies used symptom differentiation for prescribing herbal medicine to cancer patients. A total of 36 symptom differentiation were used. The kind of the herbal medicines was varied as much as the kind of symptom differentiation. Conclusion : Most of herbal medicines used for cancer patients focused on quality of life or adverse events rather than tumor size. Symptom differentiation and herbal medicine used in selected studies were too diverse to categorize. To use standardized symptom differentiation, symptom differentiation instrument should be developed and reliability test and validity test are needed.

• Journal of Korean Academy of Nursing
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• v.45 no.3
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• pp.459-468
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• 2015

Purpose: The purpose of this study was to investigate the effects of Wheel of Wellness counseling on wellness lifestyle, depression, and health-related quality of life in community dwelling elderly people. Methods: A parallel, randomized controlled, open label, trial was conducted. Ninety-three elderly people in a senior welfare center were randomly assigned to two groups: 1) A Wheel of Wellness counseling intervention group (n=49) and 2) a no-treatment control group (n=44). Wheel of Wellness counseling consisted of structured, individual counseling based on the Wheel of Wellness model and provided once a week for four weeks. Wellness lifestyle, depression, and health-related quality of life were assessed pre-and post-test in both groups. Results: Data from 89 participants were analyzed. For participants in the experimental group, there was a significant improvement on all of the wellness-lifestyle subtasks except realistic beliefs. Perceived wellness and depression significantly improved after the in the experimental group (n=43) compared to the control group (n=46) from pre- to post-test in the areas of sense of control (p =.033), nutrition (p =.017), exercise (p =.039), self-care (p <.001), stress management (p =.017), work (p =.011), perceived wellness (p =.019), and depression (p =.031). One participant in the intervention group discontinued the intervention due to hospitalization and three in the control group discontinued the sessions. Conclusions: Wheel of Wellness counseling was beneficial in enhancing wellness for the community-dwelling elderly people. Research into long-term effects of the intervention and health outcomes is recommended.

• Journal of Korean Academy of Nursing Administration
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• v.16 no.3
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• pp.348-359
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• 2010

Purpose: This study aimed to evaluate the performance of Clinical Research Nurses (CRNs) and the importance of their roles at the Regional Clinical Trial Centers (RCTCs). Method: A questionnaire focused on the role of CRNs was crafted by a researcher and the content validity was verified by a panel of experts on clinical research. The subjects of this study were 91 CRNs and Clinical Research Coordinators (CRCs), who were Korean registered nurses working at nine RCTCs. 77 subjects yielded valid data were analyzed using descriptive analysis, the Mann-Whitney U test, Spearman's rank order correlation coefficient, and Kruskal-Wallis test. Results: The performance of CRNs and the recognition in the importance of their roles were statistically significant different in age, education, CRN careers, positions, employment status and the phase of clinical trial. The role of direct caregiver was performed most often by CRNs. The role of coordinator of care and research (pre-study) was considered the most important role but performed the least frequent. Conclusions: The role of CRNs can easily be differentiated from CRCs who are not registered nurses. The domains of CRNs should be clearly identified and established. Moreover, research should be carried out on CRN training programs to cultivate competence in CRNs.

• BMB Reports
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• v.43 no.12
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• pp.836-841
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• 2010

In the era of personal genomics, predicting the individual response to drug-treatment is a challenge of biomedical research. The aim of this study was to validate whether interaction information between genetic and transcriptional signatures are promising features to predict a drug response. Because drug resistance/susceptibilities result from the complex associations of genetic and transcriptional activities, we predicted the inter-relationships between genetic and transcriptional signatures. With this concept, captured genetic polymorphisms and transcriptional profiles were prepared in cancer samples. By splitting ninety-nine samples into a trial set (n = 30) and a test set (n = 69), the outperformance of relationship-focused model (0.84 of area under the curve in trial set, P = $2.90{\times}10^{-4}$) was presented in the trial set and validated in the test set, respectively. The prediction results of modeling show that considering the relationships between genetic and transcriptional features is an effective approach to determine outcome predictions of drug-treatment.

• Journal of Ship and Ocean Technology
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• v.10 no.4
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• pp.34-48
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• 2006

The visual observation of wave condition depends on the observer's skill and experience. Also, the environmental conditions such as light and cloud heavily influence the visual measurement. In the speed test of sea trial, the wave measurement should be objective and accurate. In this paper, the problems of visual measurement and their effects on speed test are described. To overcome those problems, we developed the wave measurement system using commercial marine X-band radar, WaveFinder. The system installed at inland base was calibrated by waverider buoy and then the system's operability was defined. Onboard tests had also been performed three times for formal wave measurement to correct the ship speed. The results illustrated very good agreement with visual observation by experts. It can be concluded that the system would be useful to measure wave and swell information for the sea trial, irrespective of day and night.

• Journal of Welding and Joining
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• v.5 no.4
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• pp.47-53
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• 1987

The purpose of this study is to reexamine our test method in the light ofstatistical methods for data interpretation. Our trial to apply Plackett-Burman statistical model in multifactorial welding experiments shows that is saves much time and cost and extracts very accurate results. In this study, the parametric effects of bead shape on pulse MIG process in Cu-Ni alloy are investigated for verifying our trial.

• Journal of the korean Society of Automotive Engineers
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• v.6 no.2
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• pp.33-38
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• 1984

Research and development of automotive hydraulic brake hose has been carried out for domestic production. Four different trial products have been developed according to different design factors, and designated as Lot.. 1 through Lot. 4 respectively. Eleven kinds of static and dynamic performance tests have been conducted on each sample product of Lot. number, and the trial product by the Lot. 2 design factors was found to meet all the test specifications. Therefore, the automotive hydraulic brake hose could be localized in Korea.

• The Korean Journal of Pesticide Science
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• v.13 no.4
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• pp.209-215
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• 2009

This study was performed to produce the processing factors of pesticides in dried carrot. It is essential data for establishing the maximum residue limits (MRLs) of pesticides in dried carrot. The target pesticides were azinphos-methyl, chlorpyrifos, captan, endosulfan and triclorfon. These pesticides are included Korea's MRL list in carrot and USA's MRL list in dried foods. To infiltrate these pesticides up to each MRL level in carrot, the dipping test was performed in laboratory. Also, the supervised residue trial of the pesticide for carrot was conducted in the green house to recognize the field trial's tendency. In the dipping test in laboratory (including drying examination), the processing factors of the carrot at various concentrations and temperatures could be evaluated. In field test, the processing factors were 5.9 for azinphos-methyl, 1.7 for captan, 7.6 for chlorpyrifos, 6 for endosulfan, 0 for trichlorfon, respectively. The dipping test in laboratory on various kinds of conditions showed more precise processing factors than field trial. The processing factors obtained from the dipping test of carrot were 0~4.7 at the various concentration of the pesticides, and 0~6.7 at various drying temperature. The lower level processing factors were 0~0.6 for trichlorfon and the higher level were 3.0~5.8 for chlorpyrifos. The highest processing factor was 9.1 for captan.

• Proceedings of the KSR Conference
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• 2005.11a
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• pp.569-574
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• 2005

In this study, test standards were developed for performance verification of the high speed(350km/h) rolling-stock. The performance test system consist of three type tests; the component test for core item, the completed car test for combined function & operation and the trial driving test for compatibility & interrelationship with infrastructure.

• Journal of Navigation and Port Research
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• v.36 no.1
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• pp.15-20
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• 2012

In order to investigate the maneuverability of tug-barge, sea trial tests such as speed, acceleration/deceleration, $10^{\circ}$ turning, $20^{\circ}$ turning, $10^{\circ}/10^{\circ}$ zigzag and $20^{\circ}/20^{\circ}$ zigzag were conducted with both tug and tug-barge. From the result of turning test, longer tactical diameter and lower rate of turn of tug-barge than those of tug are obtained. From the result of the zigzag test, bigger overshoot angle of tug-barge than that of tug is obtained. When they turned or changed a course, it showed that the barge turned inner side of the trajectory of tug. For the safe navigation, the helmsman of tug-barge should be aware of these maneuvering characteristics.