• Title/Summary/Keyword: trial test

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Effect of Bee-venom Acupuncture on Upper Limb Spasticity of Stroke Patients (중풍 환자의 상지 경직에 대한 봉약침의 효과)

  • Noh, Ju-Hwan;Park, Jung-Ah;Cho, Sung-Woo;Youn, Hyoun-Min;Jang, Kyung-Jeon;Song, Choon-Ho;Ahn, Chang-Beohm;Kim, Cheol-Hong
    • Journal of Acupuncture Research
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    • v.27 no.4
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    • pp.115-125
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    • 2010
  • Objectives : The purpose of this study is to determine the effect of Bee-venom Acupuncture on upper limb spasticity control in stroke patients. Methods : Ten stroke patients with upper limb spasticity were randomly divided into two groups, a Bee-Venom Acupuncture group(group I) and a normal saline group(group II). After 1 week resting phase, this trial was used a cross-over trial. The numbers of Pharmacopuncture treatment were 3 times a week for 3 weeks. Modified Ashworth Scale(MAS), WMFT(Wolf Motor Function Test), The 10-second Test were used for evaluation of spasticity control before experiment, after 1 week, 2 weeks, 3 weeks. Results : Group I showed significant improvement(p<.05) in MAS, WMFT, The 10-second Test. But Group II showed no significant improvement(p<.05) in MAS, WMFT, The 10-second Test. The results showed significant difference in WMFT, The 10-second Test, but no significant difference in MAS between two groups. Conclusions : These results showed that Bee-venom Acupuncture might decrease upper limb spasticity and increase arm motor function in stroke patients. Further studies will be required to examine more cases in the long period for the effect on upper limb in spasticity by Bee-Venom Acupuncture.

Behavior Analysis of Particle Crushing about Sabkha Layer under Hydrotest (Sabkha층의 Hydrotest 시 입자파쇄 거동분석)

  • Kim, Seokju;Han, Heuisoo
    • Journal of the Korean GEO-environmental Society
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    • v.14 no.9
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    • pp.57-65
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    • 2013
  • Carbonate sands can be crushed under low confining pressure to achieve high compressibility. So particle crushing has significant influence on characteristics of strength and deformation. Trial embankment and hydrotest are conducted on Sabkha layer, consisting of carbonate sand to build tank structure. In this paper the settlement behavior was analyzed from each test. Particle crushing happened from 80 to 170kPa stress under compression test, and calcium was detected from chemical test. The test result came out Sabkha soil was very weak and easy to be crushing. About trial embankment test, particle crushing was not happen, and then extinction of pore water pressure and settlements were finished just during 2 days. On the other hand, the long-term settlement was happened in hydrotest. So the two test results did not correspond to each other. If loading stress is higher than yielding stress, instant settlement and secondary compression settlement are happened as a result of the particle crushing.

Performance Test and Model-Ship Correlation for a Waterjet Propulsion System (실선 물분사 추진장치 성능시험 및 모형선-실선 상관관계)

  • Jong-Woo Ahn;Chang-Yong Lee;Young-Ha Park;Jong-Ahn Chung;Byung-Hyun Kim
    • Journal of the Society of Naval Architects of Korea
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    • v.35 no.4
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    • pp.11-18
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    • 1998
  • This study describes sea trial tests for a waterjet propulsion system attached in the hybrid super high speed cargo ship named "Narae". A measuring technique of jet velocity, gross thrust and impeller torque for the waterjet system is explained. From the measured data in sea trial test, performance of the waterjet propulsion system is analyzed and compared with model test results of a similar waterjet system which was carried out in 1996. The erective horse power estimated from sea trial tests shows a good agreement with resistance test results of the model ship. The optimum rising height is estimated as 0.75 m, and the overall efficiency of the waterjet system is predicted as 0.315 at 15 knots. Useful data such as the pump performance, the jet efficiency, the losses of inlet duct and nozzle were obtained. Test results show a similar behavior to the model test results.

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Safety of Ojeok-san Extract Powder and Soft Extract in Healthy Male Volunteers, Single Center, Randomized Controlled, Cross-over Study (오적산 혼합단미엑스산제와 혼합단미연조엑스제의 안전성 평가를 위한 단일 기관, 무작위 배정, 교차 연구)

  • Shin, Hee-Ra;Park, Kyungtae;Yeom, Seung-Ryong;Kwon, Young-Dal
    • Journal of Korean Medicine Rehabilitation
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    • v.29 no.1
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    • pp.63-73
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    • 2019
  • Objectives The purpose of this study is to evaluate the safety of Ojeok-san extract powder and soft extract in healthy male volunteers. Methods Randomized controlled, cross over study was carried out in healthy male volunteers. Total 27 of 31 subjects meeting the inclusion criteria were enrolled and three subjects for waiting were included. To each group 12 subjects were randomly allocated by random number table. Group A took the extract powder in the first period and then took the soft extract in the second period. Group B took the medicine in the opposite order. Trial was conducted through two times of hospitalizations and all subjects had a seven-days of wash out period. Vital sign and laboratory test were checked before and after the medication. The mean difference of safety evaluation variables were analyzed by paired t-test (p<0.001) or wilcoxon signed rank test (p<0.05). The mean difference between two groups were analyzed by independent t-test (p<0.05) or Mann whitney test (p<0.05). Results As a result of all data related to vital sign and laboratory test in both group, There were no significant differences associated with the clinical trial drug between before and after the medication. And there was no adverse event associated with the clinical trial drug. Conclusions Both Ojeok-san extract powder and soft extract were found to be safe for healthy male volunteers.

Alternation of Topical Heat and Cold for Chronic Low Back Pain : A Randomized Controlled Pilot Trial

  • Choi, Young Doo;Jo, Su Jeong;Jung, Chan Yung;Kim, Kap Sung;Lee, Seung Deok
    • Journal of Acupuncture Research
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    • v.33 no.2
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    • pp.77-87
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    • 2016
  • Objectives : This is a pilot study for a large randomized controlled trial to investigate the efficacy and safety of a newly developed contrast therapy device-- alternating topical heat and cold -- for patients with chronic low back pain. The main objective of this study is to confirm the feasibility of the study design. Methods : The design was a randomized, 2-arm, parallel-group, single-blind, placebo controlled trial. Patients in each group received real or sham contrast therapy in an acupuncture point 10 times over four weeks. The primary outcome measure was pain intensity on a 100-mm visual analogue scale (VAS). The secondary outcomes were back-related dysfunction based on the Oswestry Disability Index (ODI), the Roland-Morris disability questionnaire (RMDQ), and range of motion of lumbar spine based on the modified Schober test (mSchober test), Finger-to-Floor distance (FTF distance), and Finger-to-Thigh distraction (FTT distraction). Results : A total of 30 subjects with chronic low back pain were randomly assigned to a contrast therapy group (n=15) or a sham group (n=15). A repeated-measures analysis of variance showed statistically significant group time interaction for VAS, RMDQ, mSchober test and FTF distance (p<0.05). The treatment group showed significant improvement in pain intensity and functional disability as compared to the sham group. Conclusion : Contrast therapy may be an effective and safe treatment for chronic low back pain.

The effect of single trial transcutaneous electrical nerve stimulation on balance and gait function in elderly people with dementia: a pilot study

  • Jung, Ju Yeon;Jung, Jin-Hwa;Hahm, Suk-Chan;Jung, Kyoungsim;Kim, Sung-Jin;Suh, Hye Rim;Cho, Hwi-young
    • Physical Therapy Rehabilitation Science
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    • v.6 no.2
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    • pp.59-64
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    • 2017
  • Objective: Elderly people with dementia experience not only cognitive dysfunction but also motor function deficits, such as balance and gait impairments. Recently, transcutaneous electrical nerve stimulation (TENS) has been used to reduce pain as well as to control muscle spasm, spasticity and motor performance in various types of subjects. The purpose of this study determined the effect of a single trial TENS on balance and gait function in elderly people with dementia. Design: A randomized controlled trial. Methods: Twenty-two subjects with dementia were assigned to the TENS group (n=12) and ten subjects were assigned to the control group (n=10) randomly. Subjects were classified into two groups: the TENS group (n=12) and the placebo-TENS group (n=10). The TENS group had electrical stimulation applied on the calf muscle for 15 minutes, while the placebo-TENS group had not received real electrical stimulation. The timed up and go test (TUG) and functional reach test (FRT) were used to measure the balance function, and the 10 meters walk test (MWT) and 6MWT were used to assess gait ability. All tests were performed before and after intervention under a single-blinded condition. Results: After intervention, there were significant improvements in TUG, FRT, 10MWT, and 6MWT results in the TENS group (p<0.05), while the placebo-TENS group did not show significant changes in all outcome measurements. There were also differences in all tests between the two groups at post-measurements (p<0.05). Conclusions: This study demonstrated that a single trial TENS application on the calf may be used to improve balance and gait function in elderly people with dementia.

Study on icebreaking performance of the Korea icebreaker ARAON in the arctic sea

  • Kim, Hyun-Soo;Lee, Chun-Ju;Choi, Kyung-Sik;Kim, Moon-Chan
    • International Journal of Naval Architecture and Ocean Engineering
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    • v.3 no.3
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    • pp.208-215
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    • 2011
  • A full-scale field trial in ice-covered sea is one of the most important tasks in the design of icebreaking ships. The first Korean icebreaking research vessel 'ARAON', after her delivery in late 2009, had a sea ice field trial in the Arctic Sea during July-August, 2010. This paper describes the test procedures and data analysis on the icebreaking performance of the IBRV ARAON. The data gathered from the icebreaking performance test in the Chukchi Sea and the Beaufort Sea during the Arctic voyage of ARAON includes the speed and engine power of the ship as well as sea ice thickness and strength data. The air temperature, wind speed and heading of the ship were also measured during each sea ice trial. The ARAON was designed to break 1 m thick level ice with a flexural strength of 630kPa at a continuous speed of 3knots. She is registered as a KR POLAR 10 class ship. The principal dimensions of ARAON are 110 m, 19 m and 6.8 m in length, breadth and draft respectively. She is equipped with four 3,500kW diesel-electric main engines and two Azipod type propulsion motors. Four sea ice trials were carried out to understand the relationship between the engine power and the ship speed, given the Arctic ice condition. The analysis shows that the ARAON was able to operate at 1.5knots in a 2.5m thick medium ice floe condition with the engine power of 5MW, and the speed reached 3.1 knots at the same ice floe condition when the power increased to 6.6MW. She showed a good performance of speed in medium ice floe compared to the speed performance in level ice. More detailed analysis is summarized in this paper.

Safety and antifatigue effect of Korean Red Ginseng capsule: A randomized, double-blind and placebo-controlled clinical trial

  • Yang, Yi;Wang, Hong;Zhang, Ming;Shi, Mengxue;Yang, Cailing;Ni, Qiang;Wang, Qi;Li, Jing;Wang, Xuemei;Zhang, Chen;Li, Zhi
    • Journal of Ginseng Research
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    • v.46 no.4
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    • pp.543-549
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    • 2022
  • Background: In physical activity or labor, the human body is in a state of high intensity stress, and all parts or physiological functions of the body respond positively to maintain or balance the need for movement. The human body has many physiological changes in the process of movement, and fatigue is the external manifestation of various complex changes inside the human body. Fatigue is also a physiological mechanism of self-protection after the body reaches a certain level of activity, which can prevent the occurrence of life-threatening excessive functional failure. The generation of fatigue is a very complex process, and its mechanism has not been concluded yet. Therefore, it is an important work to search and screen the effective components of natural plants that have anti-fatigue effect and to explore their mechanism. Methods: This was a 8-week, randomized, double-blind, placebo-controlled clinical trial. A total of 110 subjects who passed physical examination were included according to the scheme design, and randomly divided into a test group which was given KRG and a placebo control group. The calculation is carried out according to the standard of sub-high-intensity exercise test. Results: There was no adverse effect on safety index of subjects after taking red ginseng capsule. After KRG treatment, subjective strength grade is significant lower than placebo treatment. Blood lactic acid content is significantly get lower after trial in KRG group, and significant lower than placebo group. Creatine phosphokinase(CK) content is significantly get lower after trial in KRG group, and significant lower than placebo group. Conclusion: According to the criterion in the test scheme, the result shows that KRG is helpful on relieving physical fatigue.

Evaluation of the mechanical properties and clinical efficacy of biphasic calcium phosphate-added collagen membrane in ridge preservation

  • Lee, Jung-Tae;Lee, Yoonsub;Lee, Dajung;Choi, Yusang;Park, Jinyoung;Kim, Sungtae
    • Journal of Periodontal and Implant Science
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    • v.50 no.4
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    • pp.238-250
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    • 2020
  • Purpose: This study aimed to evaluate the biocompatibility and the mechanical properties of ultraviolet (UV) cross-linked and biphasic calcium phosphate (BCP)-added collagen membranes and to compare the clinical results of ridge preservation to those obtained using chemically cross-linked collagen membranes. Methods: The study comprised an in vitro test and a clinical trial for membrane evaluation. BCP-added collagen membranes with UV cross-linking were prepared. In the in vitro test, scanning electron microscopy, a collagenase assay, and a tensile strength test were performed. The clinical trial involved 14 patients undergoing a ridge preservation procedure. All participants were randomly divided into the test group, which received UV cross-linked membranes (n=7), and the control group, which received chemically cross-linked membranes (n=7). BCP bone substitutes were used for both the test group and the control group. Cone-beam computed tomography (CBCT) scans were performed and alginate impressions were taken 1 week and 3 months after surgery. The casts were scanned via an optical scanner to measure the volumetric changes. The results were analyzed using the nonparametric Mann-Whitney U test. Results: The fastest degradation rate was found in the collagen membranes without the addition of BCP. The highest enzyme resistance and the highest tensile strength were found when the collagen-to-BCP ratio was 1:1. There was no significant difference in dimensional changes in the 3-dimensional modeling or CBCT scans between the test and control groups in the clinical trial (P>0.05). Conclusions: The addition of BCP and UV cross-linking improved the biocompatibility and the mechanical strength of the membranes. Within the limits of the clinical trial, the sites grafted using BCP in combination with UV cross-linked and BCP-added collagen membranes (test group) did not show any statistically significant difference in terms of dimensional change compared with the control group.

A Study on the Reliability Demonstration for Korea High Speed Train Control System (한국형고속철도 열차제어시스템 하부구성요소 신뢰도입증에 관한 연구)

  • Lee, Jae-Ho;Lee, Kang-Mi;Kim, Young-Kyu;Shin, Duc-Ko
    • Journal of the Korean Society for Railway
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    • v.9 no.6 s.37
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    • pp.732-738
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    • 2006
  • This research provides a scheme for Highly Accelerated Stress Test that is necessary to demonstrate reliability prediction of Korean Rapid Transit Railway Train Control System sub-equipment, which is calculated by a relevant standard for failure rate prediction of electronic products. Although determining failure information generated in the process of trial running by statistic analysis is widely accepted as a measure of confirmation for reliability prediction, this research suggests the modeling for System Life Test determined by accelerating stress factors as a measure of confirmation for reliability prediction of sub-equipment unit that is generated ahead of a trial running in System Life Cycle. Consequently, the research demonstrates sub-equipment unit reliability test, which is based on the model derived from Accelerated Stress Test, according to accuracy level and the number of samples, and conducts an official experiment by making out a reliability test procedure sheet based on test time as well.