• Title/Summary/Keyword: trial test

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A Clinical Trial about Anti-anxiety and Anti-stress Effect of a modified formula consisted with Several Herbs (발아현미와 수종한약재 추출액의 스트레스 및 불안상태 개선 효과에 대한 임상연구)

  • Kim Lak Hyung;Jang In Soo;Kim Jeong Yun;Song Jeong Mo
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.17 no.6
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    • pp.1533-1537
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    • 2003
  • This double-blind randomized clinical trial was performed to evaluate the anti-anxiety, anti-stress effect of a modified formula WS-01 consisted with several herbs(Jujubae Fructus. Longanae Arillus. Poria Cocos) and germinated rice. The extract of the formula was administered (p.o) to 24 students and placebo was to 23 students for 4 weeks. STAI-KYZ(Hahn. Hakjisa), ABR2000(Meridian, Korea), CBC, LFT, U/A were checked before and after the administration period. There was no difference between the STAI score of WS-01 and that of placebo group in first test. But the STAI state anxiety score was 5.33±7.33 reduced in WS-01 group and it was 0.52±6.42 increased in placebo group in second test. this result was significant stastically. 10 students in WS-01 group showed improving result, but only 1 student in placebo group showed improving result of ABR2000 test. The result of ABR2000 was analyzed with curve 2, Regulation 2, and graph 1,2,3, because those reflect central nerve system and stressful condition of the body. There was no significant result in first and second CBC, LFT, Urine test. The results of this clinical study suggest that WS-01 has anti-anxiety, anti-stress effect, and it could be applied to various conditions or disorders related with anxiety and stress.

Reproducibility and Sample Size in High-Dimensional Data (고차원 자료의 재현성과 표본 수)

  • Seo, Won-Seok;Choi, Jee-A;Jeong, Hyeong-Chul;Cho, Hyung-Jun
    • The Korean Journal of Applied Statistics
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    • v.23 no.6
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    • pp.1067-1080
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    • 2010
  • A number of methods have been developed to determine sample sizes in clinical trial, and most clinical trial organizations determine sample sizes based on the methods. In contrast, determining sufficient sample sizes needed for experiments using microarray chips is unsatisfactory and not widely in use. In this paper, our objective is to provide a guideline in determining sample sizes, utilizing reproducibility of real microarray data. In the reproducibility comparison, five methods for discovering differential expression are used: Fold change, Two-sample t-test, Wilcoxon rank-sum test, SAM, and LPE. In order to standardize gene expression values, both MAS5 and RMA methods are considered. According to the number of repetitions, the upper 20 and 100 gene accordances are also compared. In determining sample sizes, more realistic information can be added to the existing method because of our proposed approach.

DEVELOPMENT OF GENERAL PHYSICS CAI PROGRAM FOR UNIVERSITY SCIENCE AND ENGINEERING STUDENT (이공계(理工系) 학생을 위한 일반물리학 CAI 프로그램의 개발)

  • Kim, Chang-Sik;Yoon, Sung-Ro;Cho, Young-Suk;Kim, Chul-Sung
    • Journal of The Korean Association For Science Education
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    • v.9 no.1
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    • pp.53-67
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    • 1989
  • General Physics CAI Program was developed for university science and engineering student. The program was restricted in the field of mechanics and was mainly aimed for individual tutorial. This project was supported by Government. Department of Education, physics attending their general physics classes in university. The program was written in BASIC and constructed by frame, 4 professors and 6 graduate students were involved in the project. Summary of this study is as follows. 1. The theory of CAI was illuminated from a new point of view to enhance usefullness of CAI. Also the structure of frame type CAI was studied. 2. The program was developed as follows 1) The program consisted of main program, pretest routine, tutorial routine, final test routine, and several other routines for program control. Whole program was written in BASIC. 2) 20 problems for pretest, 90 problems and subsequent hints and solutions for tutorial, 20 problems for final test were developed. 3) According to student's pretest result, tutorial course was routed through several different courses which contain different number of problems 4) The expected rate of achievment for final test was set to 75%. 5) Data of students response to problems including number of tries and time used were recorded for the purpose of achievment analisys 3. 22 students went through whole course and the results were as follows. 1) Pretest marks were widly distributed from 20 points to 100. It means that achievement of high school physics course were not enough. 2) Throughout tutorial course, students who had got higher mark in pretest answered correctly in the first trial at a higher rate of 78 %. Overall rate of correct answer in the second trial was distributed appropriatly. 3) Average mark of final test was 78.8 points, rather a higher rate of achievement than expected. This means that the program was constructed well.

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The Clinical Effect of Bosingunyang-tang on Chronic Non-bacterial Prostatitis/Chronic Pelvic Pain Syndrome : Randomized Double-blind, Placebo-controlled Clinical Trial

  • Song, Moon-Koo;Kang, Ji-Suck;Kang, Cheol-Ho;Ahn, Young-Min;Ahn, Se-Young;Doo, Ho-Kyung;Lee, Byung-Cheol
    • The Journal of Internal Korean Medicine
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    • v.29 no.3
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    • pp.800-809
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    • 2008
  • Objective : Although chronic prostatitis/chronic pelvic pain syndrcme(CP/CPPS) is a common disease, there is no consensus on the etiology or pathology and treatment. This was a double-blinded, placebo-controlled, randomized clinical trial, investigating the therapeutic effects of the traditional Korean medicine, Bosingunyang-tang(BSGYT). Method : Participants who met US National Institutes of Health (NIH) consensus criteria for CP/CPPS were entered after applying inclusion/exclusion criteria. They were randomized to the BSGYT or placebo group. and treated three times a day for 6 weeks. NIH-Chronic Prostatitis Symptom Index (NIH-CPSI) was used to estimate the clinical symptoms of CP/CPPS. Prostaglandin E2 and ${\beta}$-endorphin in prostatic fluid, collected by 2-glass pre-massage and post-massage test, were analyzed as factors associated with pain and inflammation. Result : The mean decrease in NIH-CPSI total score of the BSGYT group was 11.0 points, which is 5.7 points more than the placebo group. (Mann Whitney test P=0.038) Also the BSGYT group showed three times higher response rate than the placebo group in NIH-CPSI pain subscale score. (Fisher's exact test P=0.027) In those responders, prostaglandin E2 decreased significantly. (Wilcoxon's signed-ranks test P=0.037). No specific side effects were observed. Conclusion : After a 6-week treatment period, BSGYT improved clinical symptoms of CP/CPPS patients by decreasing PGE2 level in prostatic fluid.

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An Experimental Study on Underwater Concrete Using the Antiwashout Admixture (수중불분리성혼화제를 첨가한 콘크리트의 특성에 관한 실험적 연구)

  • 정범석;최계식;이규재
    • Proceedings of the Korea Concrete Institute Conference
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    • 1993.04a
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    • pp.47-52
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    • 1993
  • Admixtures for concrete placed underwater have been developed to the stage that they are now widely used. The use of this type of product allows concrete to be placed underwater with far less risk than was previously possible. One of the problems facing users of underwater concreting admixtures is how does one test such products in order to access their performance initially while minimizing the expense of carrying out site trials. This paper will introduce three categories of laboratory test for underwater concrete listed next : fluidity test, non-segregation test, strength test. Trial underwater concretes were ordinary Portland cement. Strength and workability development and segregation resistance properties of the concrete under the coexistence of some kinds of superplasticizer were studied for this laboratory tests.

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Durability Evaluation of a Lightweight 40-feet Container Trailer (40피트 경량 컨테이너 트레일러의 내구성 평가)

  • Kim, J.G.;Kim, J.Y.;Yoon, H.J.
    • Journal of Power System Engineering
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    • v.15 no.4
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    • pp.31-36
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    • 2011
  • The need for the lightweight of special vehicle trailer frame is substantially growing due to high gasoline prices and serious environmental issues. In this study, we develop a new lightweight sub-frame for large container trailers and evaluate its durability through a fatigue test. To this end, a reliable three-dimensional parametric finite element model of a sub-frame is constructed and then an optimized lightweight sub-frame is newly developed by using the Taguchi method. Next, we make a trial product of the optimized lightweight sub-frame and conduct a driving test to identify the driving load history at vulnerable areas. Finally, we evaluate the durability of the developed lightweight sub-frame through a fatigue test based on the load history.

A study on design and control of hydraulic test rig for performance evaluation of active suspension system (능동 현가시스템의 성능평가를 위한 유압식 시험기의 설계 및 제어에 관한 연구)

  • 손영준;이광희;이진걸
    • 제어로봇시스템학회:학술대회논문집
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    • 1996.10b
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    • pp.1445-1449
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    • 1996
  • To evaluate of active suspension, it is necessary for special equipment - so called Test Rig which can perfectly realize the road condition and the impact from the road. And most of the test rig systems controlling force accurately and rapidly consist of electro-hydraulic servo mechanism, and they need robust controller which can endure outer road change. But in the case of PID controller, we should choose its best gains by trial and error method, and once its gains are fixed, they cannot get changed, so we should reset PID controller gains respectively when the road is changed. Therefore based on the load pressure feedback compensation method, our aim at constructing electro-hydraulic test rig is not affected by various road disturbance.

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A Study on Practical PMM Test Technique for Ship Maneuverability Using System Identification Method (선박의 조종성능 추정에 있어서 시스템식별법을 이용한 PMM 시험 기법에 대한 연구)

  • 이태일;권순홍
    • Journal of Ocean Engineering and Technology
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    • v.16 no.6
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    • pp.25-31
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    • 2002
  • A system identification method is introduced to increase the prediction accuracy of a ship's maneuverability in PMM test, analysis. To improve the accuracy of linear hydrodynamic coefficients, the analysis techniques of pure sway and yaw tests are developed, and confirmed. In the analysis of sway tests, accuracy to linear hydrodynamic coefficients depends on the frequency of sway motion. To obtain nonlinear hydrodynamic coefficients for large drift angles, a combined yaw test is introduced. Using this system identification method, runs of PMM test can be reduced while retaining sufficient accuracy, compared to the Fourier integration method. Through the comparisons with sea trial results and the Fourier integration method, the accuracy and efficiency of the newly proposed system identification method, based on least square method, has been validated.

Test Database Management Program Development of Hanvit 350 (한국형 고속열차 시운전시험데이터 통합관리 프로그램 개발)

  • Lee, Tae-Hyung;Park, Choon-Soo;Choi, Seong-Hoon
    • Proceedings of the KSR Conference
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    • 2007.11a
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    • pp.1586-1589
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    • 2007
  • A prototype high-speed train system, Hanvit-350, has been developed in Korea since 1996. The train has reached the maximum speed of 352.4km/h during a test run on December 2004. It is presently undergoing various tests to stabilize its performance and to secure reliability. Until now, around 420 runs have been conducted and accumulates 190,000km trial run. The test database management program is developed using existing analysis program, LabVIEW and database program, Microsoft-SQL. The test database management program is used to analysis of test results and will be used to find out the correlation characteristics between parameters.

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Study on the Report Conformance Test of IEC 61850 based IED (IEC 61850기반 IED 대상 리포트 적합성 시험에 관한 연구)

  • Lee, N.H.;Jang, B.T.;Kim, J.H.;Song, I.J.;An, Y.H.
    • Proceedings of the KIEE Conference
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    • 2008.07a
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    • pp.241-242
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    • 2008
  • Korea Electric Power Research Institute has being carried out an IEC 61580 communication service test on IED trial products developed related to power IT project, "The verification of Performance of the Substation Automation System and Its Field Test". This paper presents reporting services of IEC 61850-8-1 and related UCA Test procedures, reporting test items are widely divided into unbuffered report and buffered report and this paper is dealing with unbuffered report.

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