• Title/Summary/Keyword: trial records

Search Result 89, Processing Time 0.023 seconds

Archival Program for Daily Life (일상생활과 기록)

  • Lee, Young-nam
    • The Korean Journal of Archival Studies
    • /
    • no.63
    • /
    • pp.167-225
    • /
    • 2020
  • The author conducted a records research named 'daily life and records.' The purpose of the research was to find an archive, if possible, that would be effective in promoting exchange and cooperation among people in their daily lives, and to distinguish what type of archive it would be, as well as how to let it naturally take place in their ordinary lives. For 4 months (August-December 2019) with 100 college students in their 20s, trial and error were repeated. There was no separate laboratory for the research, and it used regular school hours at universities. Although it is true that there was a control through power by the college system, the plot was centered on the sunshine policy. To human being there is a voluntary and positive attitude. If anyone begins to take this attitude it is difficult to stop such action. Through emotional support, this voluntary action was encouraged to take root. The experiment was an attempt to doubt the obvious, and to search for something new. From afar, this may seem irrelevant to archives. However, for the author who is a professional archivist, it was a time of records through control by Records principles. By organizing into a form of story, its archival implications are observed.

All Records in Gyeongnam Are Stored in the Gyeongsangnam-do Archives (경남의 모든 기록은 경상남도기록원으로 통한다)

  • Jeon, Ga-Hee
    • Journal of Korean Society of Archives and Records Management
    • /
    • v.19 no.3
    • /
    • pp.293-300
    • /
    • 2019
  • Gyeongsangnam-do Archives is the first permanent record management organization built in the province. In 2007, the Local Archives Management Agency was obliged to establish under the "Public Archives Management Act," and it was not until about 10 years after that the first plan was made for the construction of all 17 attempts. Unlike the initial plan, many parts of the building were reduced because of the building remodeling; nonetheless, the construction was successful. The Gyeongsangnam-do Archives, which first came to the fore in Gyeongnam, is constantly committed to the development of records management and the spread of recording culture from 2014 to 2019. However, the first time was unfamiliar and difficult because of many challenges. Furthermore, it is necessary to carry out various tasks that have been set aside such as the actual implementation of declarative laws and realization of the spread of the recording culture with citizens. Therefore, the first trial may require more responsibility than glory. As the researcher, I will manage various tasks and results of the work done at Gyeongsangnam-do Archives, as well as record every day to be recognized as a leader and director of spreading the recording culture.

Efficacy and Safety of Bolus 5-Fluorouracil and L-Leucovorin as Salvage Chemotherapy for Oral Fluoropyrimidine-Resistant Unresectable or Recurrent Gastric Cancer: A Single Center Experience

  • Muranaka, Tetsuhito;Yuki, Satoshi;Komatsu, Yoshito;Sawada, Kentaro;Harada, Kazuaki;Kawamoto, Yasuyuki;Nakatsumi, Hiroshi;Sakamoto, Naoya
    • Journal of Gastric Cancer
    • /
    • v.16 no.3
    • /
    • pp.177-181
    • /
    • 2016
  • Purpose: The International Organization for Standardization-5fluorouracil (FU) 10 trial found that bolus 5-FU and l-leucovorin was not inferior to S-1 in the treatment of gastric cancer (GC). Continuous 5-FU and the rapid injection of 5-FU have different anti-cancer effects. Thus, bolus 5-FU and l-leucovorin treatment might be useful for oral FU-resistant GC. Materials and Methods: We retrospectively analyzed the medical records of all patients with S-1 or capecitabine-resistant, unresectable, or recurrent GC treated with bolus 5-FU and l-leucovorin between January 2010 and December 2015 at Hokkaido University Hospital. The bolus 5-FU and l-leucovorin regimen consisted of intravenous l-leucovorin ($250mg/m^2/2h$) and bolus 5-FU ($600mg/m^2$) administered once weekly followed by a 2-week rest period; each cycle was repeated every 8 weeks. Results: A total of 14 patients were identified. The disease control rate was 35.7%. The median progression-free survival was 1.6 months (95% confidence interval [CI], 1.3~2.0 months), and the median overall survival was 6.3 months (95% CI, 4.7~7.9 months). No patient died from treatment-related causes. The most common severe adverse event associated with bolus 5-FU and l-leucovorin was neutropenia, which occurred in 21.4% of patients. Conclusions: Bolus 5-FU and l-leucovorin treatment might be useful for oral FU-resistant GC. We are planning a multi-center prospective phase II trial to evaluate the efficacy and safety of bolus 5-FU and l-leucovorin treatment for pre-treated unresectable or recurrent GC to confirm the results of this limited, retrospective study.

A Randomized Controlled Trial To Motivate Worksite Fecal Occult Blood Testing (암위험사정이 직장인의 혈변검사에 미친 영향에 관한 실험연구)

  • 이정렬
    • Journal of Korean Academy of Nursing
    • /
    • v.20 no.3
    • /
    • pp.300-306
    • /
    • 1990
  • Colorectal cancer is second only to lung cancer as a cause of death due to cancer in the united States. Studies have shown that fecal occult blood(FOB) tests are effective in detecting colorectal cancer in its early stages. To motivate worksite FOB testing, a randomized controlled trial was conducted. Employees 40 years or older from three federal agencies in Washington State were randomized to a control group(n=139) which received a letter stating the availability of the FOB test at the worksite clinic or to an intervention group(n=139) which received the letter about facts on colorectal cancer and a Colorectal Cancer Risk Appraisal. The Colorectal Cancer Risk Appraisal included a feedback on an individual's risk of developing colorectal cancer compared to his / her peers in terms of ‘normal’, ‘moderate’, or ‘high’ risk status. After 3 months, a follow-up questionnaire was sent to all participants to measure the effectiveness of the intervention. In the analysis of the three major outcomes, two possible confounding factors(dietary fat and family history of colorectal cancer) were controlled by logistic regression. Based on a review of the worksite clinic records, the Intervention group had 4.3% higher compliance rate with the FOB test during the follow-up period compared to the control group(p=.10). The largest effect of the intervention was on the employees' intention to get a FOB test within the next year(62.6% in the intervention group vs. 36.2% in the control group, OR=3.18, p<.001). In the final Multivariate logistic model, the employees who were more likely to intend to get a FOB test within the next year were in the intervention group ; were at ‘moderate’ or ‘high’ risk of colorectal cancer ; knew more about the availability of the FOB test at the worksite clinic ; and had a FOB test during the last three years.

  • PDF

Clinical Analysis of Foreign Bodies in Gastrointestinal Tract in Children (소아에서 위장관내 이물질의 임상적 고찰)

  • Choi, Eunsoo;Lee, Hyo Gyun;Choi, Soo Jin Na;Chung, Sang Young
    • Advances in pediatric surgery
    • /
    • v.20 no.1
    • /
    • pp.12-16
    • /
    • 2014
  • Foreign body ingestion is a common problem among paediatric populations. Most of the ingested foreign bodies spontaneously pass through the gastrointestinal tract, but approximately less then 10% of them remain without being discharged, and trigger complications. Therefore, proper evaluation and treatment according to the situation is required. In this study, clinical progress and complications were analyzed according to the clinical features and treatment in children who ingested foreign bodies. Among pediatric patients under 18 who were admitted to Chonnam National University Hospital after ingesting foreign bodies between January 2008 to June 2012, only the patients who had their foreign body in the gastrointestinal tract were included in this study. Based on medical records, age, type of foreign body, time spent till admission, and whether the endoscopy was done or not, complication were researched retrospectively. According to symptoms and plain abdomen X-ray findings, treatment was chosen and conducted among endoscopy, observation and emergency operation. Among 273 patients, 9 (3.3%) of them had surgical removal. Seven (2.6%) of them had an emergency operation on the day of admission, and the rest 2 (0.7%) had operation during observation. Removal through initial endoscopic approach was tried in 157 (57.5%) patients. Eleven (70.8%) of them had their foreign body removed at the initial trial, and 5 (4.9%) of them at the second trial. Among 109, who were on observation status, 9 (8.3%) of them needed endoscopic removal, and 2 (1.8%) of them suffered from surgical removal. It is thought to be better to approach slowly considering the type, size and symptoms in foreign body ingestion of pediatric patients, rather than immediate and invasive removal.

The development of a mobile u-Health program and evaluation for self-diet management for diabetic patients

  • Ahn, Yun;Bae, Jeahurn;Kim, Hee-Seon
    • Nutrition Research and Practice
    • /
    • v.10 no.3
    • /
    • pp.342-351
    • /
    • 2016
  • BACKGROUND/OBJECTIVES: This study aims to develop a mobile nutritional management program for integration into the already developed web-based program, Diabetes Mellitus Dietary Management Guide (DMDMG) for diabetic patients. Further, we aim to evaluate the amended DMDMG program. SUBJECTS/METHODS: The mobile application based on an Android operating system includes three parts: 1) record of diet intake, which allows users to take pictures of the meal and save to later add diet records into DMDMG; 2) an alarm system that rings at each meal time, which reminds users to input the data; 3) displays the diet record and the results of nutrient intake, which can be also viewed through the web program. All three parts are linked to the web-based program. A survey was conducted to evaluate the program in terms of nutrition knowledge, dietary attitude, eating behavior and diet intake by non-equivalent control group design among diabetic patients with 14 DMDMG users and 12 non-user controls after a one-month trial of DMDMG. RESULTS: Non-users did not use the program, but participated in the weekly off-line nutrition classes for one month. The program users showed increased healthful dietary behavior (P < 0.01) and dietary attitude scores (P < 0.05). More DMDMG users had higher nutrition knowledge scores after one-month trial than non-users. However, dietary intake significantly increased in non-user group for calcium and sodium (P < 0.05) while the user group did not show significant changes. CONCLUSIONS: The program has created positive changes in patients' dietary life. All the users were satisfied with the program, although some expressed minor difficulties with an unfamiliar mobile app.

Acupuncture for Symptomatic Rotator Cuff Disease: A Systematic Review and Meta-Analysis

  • Choi, Seoyoung;Lee, Jisun;Lee, Seunghoon;Yang, Gi Young;Kim, Kun Hyung
    • Journal of Acupuncture Research
    • /
    • v.38 no.1
    • /
    • pp.20-31
    • /
    • 2021
  • The objective was to evaluate the effectiveness and safety of acupuncture for patients with rotator cuff diseases. There were 12 electronic databases and 3 trial registries searched up to November 30th, 2019. All randomized trials were eligible, regardless of language, date of publication, or settings. The primary outcomes were pain, shoulder function, and proportion of improved participants assessed within 12 weeks of randomization of the trial. The Cochrane risk of bias for the studies was assessed. Effects sizes were presented as a risk ratio, mean difference, or standardized mean difference with a 95% confidence intervals. Grading of Recommendations Assessment, Development and Evaluation approach was adopted to rate certainty of evidence. Of the 3,686 records screened, 28 randomized trials (2,216 participants) were included in this review. The types of acupuncture included manual acupuncture, dry needling, electroacupuncture, acupotomy, warm needle acupuncture, and fire needle acupuncture. All of the studies had an unclear or high risk of bias related to more than 1 domain. Significant benefits of acupuncture in terms of pain and shoulder function were observed in all comparisons, however, the proportion of improved participants was not described in 2 comparisons. There was substantial heterogeneity among meta-analyzed trials. No serious harm was observed. For primary outcomes, the overall certainty of evidence was very low. There was very low certainty of evidence for the benefits of acupuncture for patients with rotator cuff diseases. The safety of acupuncture remains unclear due to the incompleteness of reporting. Future well-designed randomized trials with transparent reporting are required.

Effectiveness of low-level laser therapy in facilitating maxillary expansion using bone-borne hyrax expander: A randomized clinical trial

  • Abdelwassie, Sara Hassan;Kaddah, Mohammed Amgad;El-Dakroury, Amr Emad;El-Boghdady, Dalia;Abd El-Ghafour, Mohamed;Seifeldin, Nouran Fouad
    • The korean journal of orthodontics
    • /
    • v.52 no.6
    • /
    • pp.399-411
    • /
    • 2022
  • Objective: The objective of this randomized clinical trial was to study the skeletal and dental effects of low-level laser therapy (LLLT) along with a miniscrew-assisted expander (Hyrax) after six months of retention. Methods: After sequence generation, concealed allocation, and implementation, 24 female patients were randomly divided (1:1) into two-groups: bone-borne rapid palatal expansion (BBE) without LLLT (n = 12) and BBE with LLLT (n = 12). Eligibility criteria included female patients aged 10-13 years old with bilateral posterior crossbites. Intraoral and extraoral photographs, cone-beam computed tomography images, and digital study models were obtained before expansion and six months after retention. The 7 mm Hyrax appliance was anchored to four palatal mini-screws, which were activated twice daily for 15 days, then locked and kept in place as a retainer. LLLT was performed in the laser group during expansion and retention, according to the guidelines provided. Results: The records of 24 patients were analyzed. According to the post-retention measurements, both groups showed a significant increase in nasal and maxillary widths and total facial height. In the laser group, the Sella-Nasion-Point A and Point A-Nasion-Point B angles and the interpremolar apical distance were significantly increased. Conclusions: Within the limitations of this study, the results suggest that the parameters and protocol of LLLT do not clinically affect the efficiency of BBE in prepubertal and pubertal patients.

A Study on Current Status and a New Direction for Archival Education (기록 전문직 양성 프로그램의 현황과 개선방향에 관한 연구)

  • Chung, Yeon-Kyoung
    • Journal of Korean Society of Archives and Records Management
    • /
    • v.10 no.1
    • /
    • pp.99-118
    • /
    • 2010
  • The purposes of this study are to find core domains of archival knowledge based upon two guidelines from foreign countries, and to analyze current status of archival education programs and curriculums in Korea and other countries. Based upon the analysis, several new directions for archival education in Korea are suggested as follows: strengthening the archival graduate programs for archival profession, developing and expanding interdisciplinary courses based upon participation and trial of various related disciplines, increment of graduate credits, hiring of the Ph. D. full-time faculty in archival studies, strengthening internship and research courses, developing a standard curriculum for archival education, and active participations and partnerships among archival graduate schools, professional archival societies, and archival related institutions.

Analysis of Hospital Admissions Related to Adverse Drug Events Using ADE Signals

  • Lee Suk-Hyang;Kim Hye-Young;Lee Kyung-Hoon;Koo Hyun-Kyung;Kim Yoon
    • Biomolecules & Therapeutics
    • /
    • v.14 no.1
    • /
    • pp.56-65
    • /
    • 2006
  • Adverse drug events (ADEs) are the most common type of adverse events in medical practice. Hospital admissions related to ADEs cost high and should be monitored to prevent them. While concerns about the ADEs are increasing, the frequency and characteristics of admissions related to ADEs have not been reported in Korea. The objective of the study was to assess the rate of hospital admission related to ADEs and their characteristics through ADE signal-based retrospective reviews of medical records. As results, a total of 1,420 patients had ADE signals suggesting potential ADEs from 3,494 patients who discharged from an academic medical center over one month period. Six pharmacists independently assessed the presence of ADEs after the review of patients' medical records. Among the 3,494 discharges, 62 admissions (1.8%) were found to be realted to ADEs. Of admissions with ADEs, 83.9% were moderate (category F by the NCC MERP classification), 37.2% were preventable, and 85.5% were type A reaction. The most frequent suspected drugs causing ADEs were antineoplastics (48.9%), and the most frequent ADE signal detecting hospital admissions related to ADEs was white blood cell count (24.2%). Hospital admissions related to ADEs were found through screening the ADE signals. The ADE signal-based retrospective review could be a practical approach for identifying hospital admissions related to ADEs.