• Title/Summary/Keyword: trial

Search Result 8,033, Processing Time 0.041 seconds

The effects of Sa-am Acupuncture Simpojeongkyeok Treatment on Hwa-byung : Randomized, patient-assessor blind, placebo-controlled acupuncture, pilot clinical trial (화병에 대한 사암침 심포정격의 치료 효과 : 환자-평가자 눈가림, 무작위배정 대조군 임상시험)

  • Choi, Woo-Jin;Lee, Seung-Gi;Son, In-Bong;Sun, Seung-Ho
    • Journal of Oriental Neuropsychiatry
    • /
    • v.22 no.2
    • /
    • pp.1-13
    • /
    • 2011
  • Objectives : The purpose of this research is to examine the effects of Sa-am acupuncture Simpojeongkyeok treatment on Hwa-byung. Methods : The study was performed through a patient-assessor blind, randomized, placebo-controlled trial in which the volunteers, data collector and analyst were unaware of individuals which were receiving the treatment. Fifty volunteers were divided into a trial and a control group, each of which consisted of 25 subjects. The trial group was treated with Sa-am acupuncture Simpojeongkyeok, while needle insertion at non-acupoints was given to the control group. The Likert scale for major symptoms of Hwa-byung was measured as the 1st evaluative instrument, and then a comparative analysis was conducted by comparing the results with those measured by of STAXI-K, STAI-K and BDI-K. Results : In the Likert scale comparison of major symptoms, total scores in both groups were decreased after treatment. However, a more significant decrease was found in those of trial group compared to those of the control group from a statistical perspective. The results measured by BDI scores also decreased significantly in the trial group after treatment. In comparison of STAXI and STAI scores, there were no significant differences found between the groups. Conclusions : The results suggest that Sa-am Acupuncture Simpojeongkyeok treatment is effective in the treatment of Hwa-byung.

Critical reviews of job training and employment support trial plans for immigrant women by marriage (결혼이민여성의 직업교육훈련 및 취업관련 시행계획의 비판적 검토)

  • Seong, Hyang-Sook
    • Journal of the Korea Academia-Industrial cooperation Society
    • /
    • v.14 no.12
    • /
    • pp.6186-6195
    • /
    • 2013
  • The aim of this study was to learn what directions need to be reflected when establishing the next-term trial plans by analyzing the current trial plans being implemented in Korea regarding job training and employment support for immigrant women by marriage. For this purpose, the job training suggested in the Healthy Family Basic Plan and Multicultural Family Policy Basic Plan as well as in the Basic Economic Activity Stimulation Plans for Out-of-employment Women were analyzed. Based on this, job training was reconstructed into four categories: 1) education and training program; 2) human resource development; 3) employment support; and 4) delivery system. For the analysis, the policy analysis methods reported by N. Gilbert and P.Terrile were used. The results showed that the current trial plans exhibited immaturity in the Tomorrow Learning Card and Successful Employment Package as well as in the specialization process, lack of a human resource development system, and the absence of governance. Several proposals should consider these when making the next-term trial plans.

The Effects of Acupuncture Treatment on Hwa-byung patient's Insomnia: Patient-assessor blind, Randomized, Placebo-controlled Clinical trial (화병환자의 불면증상에 대한 침치료 유효성 평가연구: 환자-평가자 눈가림, 무작위배정, 일반대조군 임상시험)

  • Lee, Go-Eun;Kim, Nam-Kwon;Kim, Hang-Yi;Kang, Hyung-Won
    • Journal of Oriental Neuropsychiatry
    • /
    • v.23 no.1
    • /
    • pp.31-48
    • /
    • 2012
  • Objectives: The purpose of this research is to examine the effects of acupuncture treatment on Hwa-byung patient's insomnia. Methods: The study was performed through a patient-assessor blind, randomized, placebo-controlled trial in which the volunteers, data collectors and analysts were unaware of individuals who were receiving the treatment. A total of thirty-seven volunteers were divided into 2 groups. 18 subjects were placed into a trial group and 19 subjects into a control group by a randomization table. The trial group was treated on bilateral Shigu, Ahnmyun, B62 (Shinmaek), and K6 (Chohae), while the control group was not given any other treatment. The ISI(Insomnia Severity Scale) was measured as the 1st evaluative instrument, and then a comparative analysis was conducted by comparing the results with those measured by a Likert scale for major symptoms of Hwa-byung, PSQI, Hwa-byung scale, BDI, STAI, and STAXI. Results: In the ISI, PSQI, and the Likert scale regarding major symptoms of Hwa-byung, Hwa-byung scale, BDI, and STAI, more significant decreases were found in those concerning the trial group compared to those of the control group from a statistical perspective. However, in the STAXI, regarding the trial group, there was no significant decrease compared to the control group. Conclusions: The results suggest that acupuncture treatment is effective in the treatment regarding Hwa-byung patients who suffer from insomnia.

Effects of Different Fatty Acids and Levels on the Lipogenesis Capacity and Lipolysis Rate of Broilers In Vitro

  • Lien, T.F.;Wu, C.P.;Chen, K.L.;Yang, K.H.
    • Asian-Australasian Journal of Animal Sciences
    • /
    • v.13 no.9
    • /
    • pp.1285-1289
    • /
    • 2000
  • This study investigated the lipogenesis capacity of hepatocytes and lipolysis rate of adipocytes of broilers as affected by different fatty acids (trial one) and different linoleic acid (C18:2) levels (trial two). Twenty 6-wk old broilers were used; their hepatocytes and adipocytes were isolated for the in vitro study. In trial one, four treatments were tested. The control group in which no fatty acid was added, and the test groups to which were added $300{\mu}M$ of C16:0, C18:1 and C18:2, respectively. For trial two, different levels (0, $300{\mu}M$ and 1 mM) of C18:2 combined to fatty acid-free bovine serum albumin (BSA) were added to the medium. According to results of trial one, added fatty acids significantly reduced the incorporation by hepatocytes of [U,$^{14}C$]glucose into total lipid (p<0.05); the lipogenesis capacity in C18:2 group was the lowest. Although a similar pattern was found with [l,$^{14}C$]acetate, the groups only slightly differed in terms of lipogenesis capacity (p=0.11). In addition, the C18:2 group had a significantly (p<0.05) greater lipolysis rate than the C16:0 and control groups. Results of trial two indicated that C18:2 significantly (p<0.05) reduced lipogenesis capacity both for [U,$^{14}C$]glucose and [l,$^{14}C$]acetate, and markedly stimulated the lipolysis rate (p<0.05), displaying a dose response. Results presented herein demonstrate that C18:2 can reduce lipogenesis capacity and stimulate the lipolysis rate in broilers.

Speed Trial Analysis of Korean Ice Breaking Research Vessel 'Araon' on the Big Floes (큰 빙판에서 아라온 호 쇄빙 속도 성능 해석)

  • Kim, Hyun Soo;Lee, Chun-Ju;Choi, Kyungsik
    • Journal of the Society of Naval Architects of Korea
    • /
    • v.49 no.6
    • /
    • pp.478-483
    • /
    • 2012
  • The speed performances of ice sea trial on the Arctic(2010 & 2011) area were shown different results depend on the ice floe size. Penetration phenomena of level ice was not happened on medium ice floe and tore up by the impact force because the mass of medium ice floe is similar to the mass of Araon which is Korean ice breaking research vessel and did not shut up by the ice ridge or iceberg. The sea trial on the Amundsen sea was performed at the big floe which is classified by WMO(World Meteorological Organization). Three measurements of ice properties and five results of speed trial were obtained with different ice thicknesses and engine powers. To evaluate speed of level ice trial and model test results at the same ice thickness and engine power, the correction method of HSVA(Hamburg Ship Model Basin) was used. The thickness, snow effect, flexural strength and friction coefficient were corrected to compare the speed of sea trial. The analyzed speed at 1.03m thickness of big floe was 5.85 knots at 10MW power and it's 6.10 knots at 1.0m ice thickness and the same power. It's bigger than the results of level ice because big floe was also slightly tore up by the impact force of vessel based on the observation of recorded video.

Study for trial project of Intelligent Train Control System (MBS) at Korail Bundang Line (분당선 지능형열차제어시스템 (MBS) 시범설비구축 사업에 관한 고찰)

  • Kim, Yun-Bae;Yoon, Ho-Sok
    • Proceedings of the KSR Conference
    • /
    • 2008.06a
    • /
    • pp.339-342
    • /
    • 2008
  • In this paper, the lessons and learns are introduced from the result of the trial project which is the first CBTC(Communication Based Train Control System) at Korail Bundang Line. This project has started end of 2002 and finished recently by Samsung SDS. The main purpose of this project was that new technology was seek for next generation of railway signal control system adapted in Korea. In 2002, there was no any revenue service system using Radio Frequency CBTC in the world at that time. Just a few trial project was on going in USA and EU. In well developed cities, the metro system have been built and old enough therefore they have to be considering re-signalling their existing system with advanced system for increasing availabilities of line usage and safety. This Bundang Line Trial Project was the first Korean CBTC project for above reasons. Most sub systems have been developed using local technology such as Electronics Controlled Interlocking System and Track Circuit Systems etc. Specially, in this project the RF-Communication devices are developed by local technology using DSSS(Direct Sequency Spread Spectrum) instead of FHSS(Frequency Hopping Spread Spectrum). This project has lasted for more than five years originally planned for three years because it was only accessible only night time in the main line from Ori to Suseo about 20km long. Each night only 2 and half hours are available to use the main line. Now the trial project has been done successfully with meet the customer's requirement, therefore the upgrade the mainline of Bundang line and another extension area up to Wangsipli to make revenue service using this new technology. This paper shows this result of the trial project and the strategy of upgrade and extension project as well.

  • PDF

Effects of Kamigyemyoungsan and Each Compositive Herbs on the Intravascular Coagulation and Subcutaneous Hematoma in Rats (加味鷄鳴散 및 그 構成藥物이 白鼠의 瘀血病態模型에 미치는 影響)

  • Ji, Sun-Young;Jung, Dae-Gyu
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
    • /
    • v.10 no.1
    • /
    • pp.1-38
    • /
    • 1997
  • This study was performed to investigate the effects of Kamigyemyoungsan and each compositive herbs on the intravascular coagulation and subcutaneous hematoma. The intravascular coagulation was induced by the injection of endotoxin into the caudal vein of the rats. These rats were treated with endotoxin after administering orally extracts of Kamigyemyoungsan and each compositive herbs. Then the number of platelet, prothrombin time, the concentration of fibrinogen and FDP(fibrinogen degration product), hematocrit and RBC and WBC were measured. The subcutaneous hematoma was induced by the subcutaneous injection of the autologous whole blood to produce clotting in situ in rats. Then the extracts of Kamigyemyoungsan and each compositive herbs were administered orally. The lesions were then dissected and observed. The results were obtained as follows ; 1. The number of platelets of the trial groups was increased as compared with the control group, and revealed significance in sample Ⅰ. 2. The concentration of fibrinogen of the trial groups was increased as compared with the control group, and revealed significance in sample Ⅰ, sampleⅡ and sample Ⅴ. 3. The prothrombin time was shortened significantly in the trial groups, except sampleⅡ and sampleⅣ as compared with the control group. 4. The concentration of FDP decreased in the trial groups, and revealed significance in sample Ⅰ and sample Ⅵ as compared with the control group. 5. The hematocrit significantly increased in sample Ⅰ, sampleⅢ and sample Ⅵ as compared with the control group. 6. The number of RBC significantly increased in sample Ⅵ only as compared with the control group. 7. The number of WBC significantly increased in the trial groups, except sampleⅣ and sample Ⅵ as compared with the control group. 8. Histologically, the lesions in the trial groups showed significantly thinner fibroblastic neomembrane than the control group, except sampleⅢ. According to the above results, it is considered that Kamigyemyoungsan and each compositive herbs have inhibitive effects on the thrombosis and the fibroblastic neomembrane development. Therefore, it seems to be applicable to the diseases related to thrombosis and hematoma.

  • PDF

Review of Ethical and Scientific Aspects of Acupuncture Clinical Trials Pointed Out by Institutional Review Board a Part of Development Process of the Acupuncture and Moxibustion Clinical Research Guideline (침구임상시험 가이드라인 개발과정에서 IRB의 윤리적·과학적 지적사항 사례 조사 연구)

  • Leem, Jung Tae;Lee, Seung Hoon;Han, Ga Jin;Kim, Eun Jung;Seo, Byung Kwan;Kim, Tae Hun;Lee, Seung Deok;Kim, Jong Uk;Yu, A Mi;Nam, Dong Woo;Lee, Jun Hee
    • Journal of Acupuncture Research
    • /
    • v.32 no.2
    • /
    • pp.11-21
    • /
    • 2015
  • Objectives : To improve quality of clinical research for acupuncture and moxibustion, a guideline for clinical research protocol is needed. While developing a guideline for acupuncture and moxibustion clinical research, we reviewed the ethical and scientific aspects of protocols pointed out by the institutional review board. This will offer practical assistance to the researchers. Methods : Ethical and scientific aspects of acupuncture and moxibustion research protocols reviewed by Kyung Hee University Korean Medicine Hospital Institutional Review Board were gathered and reviewed. Results : Ethical and scientific aspects of protocol review was reported. Conclusions : The example of review will be helpful for new researchers when developing acupuncture and moxibustion clinical research protocol.

A Study on Assessment of MTF Performance and Theoretical Analysis of Convex Trial Lenses (볼록 검안렌즈의 MTF 성능 분석 및 이론적 해석에 대한 연구)

  • Bang, Hyun Jin;Lee, Jong Ung;Son, Byung Ho;Ahn, Kyo Hoon;Choi, Eun Jung
    • Korean Journal of Optics and Photonics
    • /
    • v.24 no.5
    • /
    • pp.217-223
    • /
    • 2013
  • White light MTF(Modulation Transter Function)s of biconvex trial lenses from 10 to 20 diopter (D) were represented as a function of angular frequency and visual acuity, and then they were compared with AIM(Aerial Image Modulation) curves. All of the biconvex trial lenses evaluated in on-axis mode had MTF performance that could resolve Landolt's ring up to visual acuity 2.0. However, in a half field angle of five degrees, the trial lens of 10 diopters was able to resolve Landolt's ring up to visual acuity 0.9, and that of 20 diopter only up to visual acuity 0.8. This means that the trial lenses in the case of a half field angle of five degrees do not have sufficient resolution to measure visual acuity by 1.0.

The Comparison of Pedalling Performance to according to the Position of Shoe Cleat in Triathletes During Cycling (자전거 운동 중 클릿의 위치 변화에 따른 페달링 수행능력 비교)

  • PARK, Chan-Ho;CHOI, Bo-Kyung;HEO, Bo-Seob;KIM, Yong-Jae
    • Journal of Fisheries and Marine Sciences Education
    • /
    • v.29 no.2
    • /
    • pp.537-543
    • /
    • 2017
  • The purpose of this research is to investigate the effects of different shoe-cleat position on pedalling performance. Four male elite triathletes(age: $22.00{\times}2.16years$, height: $175.12{\pm}8.06cm$, weight: $71.20{\pm}7.89kg$, body fat: $16.62{\pm}3.56%$) and three female elite triathletes(age: $20.00{\pm}1years$, height: $158.40{\pm}2.42cm$, weight: $51.30{\pm}3.89kg$, body fat: $19.26{\pm}2.28%$) participated in 10km time trial and 30sec time trial pedaling tests with the individual time trials based on different shoe-cleat position(cleat front: CF, cleat back: CB). The subjects performed one trial with each type of shoe-cleat position. Maximal power output and average speed were not significantly different during 30s time trial in CF compared with CB. Average power, RPM, and HR were not significantly different during 10k time trial in CF compared with CB. Split time in 1km, 5km, 9km were significantly reduced during 10k time trial in CB compared with CF. We conclude that there was performance advantage in CB using shoe-cleat back position in comparison with CF using shoe-cleat front position.