• Asian Pacific Journal of Cancer Prevention
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• v.15 no.20
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• pp.8797-8800
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• 2014

Objective: To analyze cost-effectiveness of morphine, MS contin and oxycodone in the treatment of cancer pain, providing guidance for rational drug use in the clinic. Methods: Confirmed by histology, a total of 171 patients with various cancers who required analgesic treatment were selected and divided into 3 groups, 57 cases for each group, given morphine, MS contin and oxycodone, respectively. If there appeared a poor short-term effect or aggravated sudden pain during the treatment, a short-acting morphine injection was given and adverse reactions were processed by symptomatic treatment. The pain relief rate and adverse reactions of groups were observed and pharmacoeconomics evaluation was undertaken. Results: The pain relief rates with morphine, MS contin and oxycodone were 89.5%(51/57), 91.2%(52/57) and 93.0%(53/57), respectively, with no difference samong groups (${\chi}^2=4.4489$, P=0.6162). The occurrence rates of adverse reactions were 59.7%(34/57), 54.4%(31/57) and 43.9%(25/57), again with no significant variation (P>0.05). The ratios of cost-effectiveness (C/E) for the 3 groups were $14.6{\pm}7.21$, $15.0{\pm}7.44$ and $16.1{\pm}8.10$. When the price of 3 kinds of analgesics was reduced by 10%, the ratios of cost-effectiveness were $12.2{\pm}6.53$, ($13.4{\pm}6.08$ and $14.5{\pm}6.74$ but there was no differences when compared with before the price adjustment (t=1.86, P=0.0651; t=1.30, P=0.1948; t=1.17, P=0.2453). Conclusion: Morphine, MS contin and oxycodone give similar pain relief and adverse reaction rates but of all, morphine is the preferred drug for the treatment of cancer pain from the perspective of pharmacoeconomics.

• Journal of Korean Society of Water and Wastewater
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• v.14 no.1
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• pp.45-53
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• 2000

The optimum operation of domestic wastewater treatment plant can give influence on operational cost and future expansion in Korea where has 93 operational domestic wastewater treatment plants. Also, the study on optimum operation can reduce operation cost and budget of municipalities whom have responsibility of wastewater treatment plant operation. In this study, 9 domestic wastewater treatment plants which can represent 93 plants in Korea have been selected and operational data are gathered. The collected data are inputted to computer simulator based on IAWQ's Activated Sludge Model No.1 and optimum operation methods are developed. Also, the electric power for aeration which has large portion of overall operation cost are calculated based on design and operation conditions and these are compared. In this study, it was found that design wastewater characteristics are 1.6 times higher than those of daily maximum except for E plant and that estimation methods for design wastewater characteristics have to be improved. Based on computer simulation, we found there is no need to operate all aeration tanks due to weak influent overall power for aeration can be reduced to about 43% of design one.

• Journal of the Korean institute of surface engineering
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• v.43 no.5
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• pp.211-216
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• 2010

Vacuum carburizing process is well known process for its environment-friendly, low-cost, high-quality characteristics, compared with gas carburizing. In this study, a research was carried out to develop a process of vacuum carburizing for essential components of automotive transmission that is difficult to control its distortion. As a result, vacuum carburizing process is superior to gas carburizing in terms of cost, environment and quality.

• Journal of Korean Society of Water and Wastewater
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• v.16 no.6
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• pp.700-709
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• 2002

Present condition of the Youngsan River pollution is serious. Concentrations of organic materials and nutrients are high and algal bloom takes place frequently. The pollution is mainly caused by domestic wastewater input from urban areas like Kwangju and Naju City. In this study, 6 times of water quality surveys were done for mainstream and tributaries. Delivery ratios of each tributaries are calculated with the water quality and flow data. With Arc/View GIS, sub-basin are divided and pollution loads are estimated. These data are used for water quality modeling. River quality improvement effects are analysed with 5 scenarios including process upgrade of present WWTPs and construction of new WWTPs. These scenarios are applied for the Youngsan River based on the 7Q10 and Q275. And total wastewater treatment cost in the basin is analysed for each scenario.

• Journal of The Korean Society of Integrative Medicine
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• v.4 no.3
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• pp.39-47
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• 2016

PURPOSE : This study attempts to find the effects of water perturbation exercise performed on stroke patients in their physiological cost index and gait ability tests. METHOD : The subjects were 30 stroke patients, water perturbation exercise group was performed 3 day per week, for 40 minutes a day, for a period of eight weeks. The physiological cost index and gait of all subjects were assessed by using the polar, 6 Minute Walk Test (6MWT), and 10 meter Walk Test(10mWT) at pre training and post training. Paired t-test was used to analyze change before and after intervention in group. Pearson's correlation was used to analyze correlation of all variables. RESULT : Water perturbation exercise group showed increased physiological cost index. Water perturbation exercise increased gait ability, showing a significant difference. Showing the correlation between the relatively high amount between physiological cost index and 6 minutes walking test. CONCLUSION : From the result of the study, we found that water perturbation exercise was effective in improving physiological cost index and gait ability. The patient is considered to be used by itself to involve the treatment and the risk of falling from the lowered state into the treatment method for the intensive treatment of stroke patients to be useful in improving the cardiovascular system and ability to walk. Through underwater training for stroke patients in the future on the basis of this study it is considered to require additional clinical studies on the impact on daily living and quality of life of stroke patients.

• The Korean Journal of Pain
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• v.31 no.1
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• pp.27-38
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• 2018

Background: Related to escalating health care costs and the questionable effectiveness of multiple interventions including lumbar facet joint interventions, cost effectiveness or cost utility analysis has become the cornerstone of evidence-based medicine influencing coverage decisions. Methods: Cost utility of therapeutic lumbar facet joint nerve blocks in managing chronic low back pain was performed utilizing data from a randomized, double-blind, controlled trial with a 2-year follow-up, with direct payment data from 2016. Based on the data from surgical interventions, utilizing the lowest proportion of direct procedural costs of 60%, total cost utility per quality adjusted life year (QALY) was determined by multiplying the derived direct cost at 1.67. Results: Patients in this trial on average received $5.6{\pm}2.6$ procedures over a period of 2 years, with average relief over a period of 2 years of $82.8{\pm}29.6$ weeks with $19{\pm}18.77$ weeks of improvement per procedure. Procedural cost for one-year improvement in quality of life showed USD $2,654.08. Estimated total costs, including indirect costs and drugs with multiplication of direct costs at 1.67, showed a cost of USD $4,432 per QALY. Conclusions: The analysis of therapeutic lumbar facet joint nerve blocks in the treatment of chronic low back pain shows clinical effectiveness and cost utility at USD $2,654.08 for the direct costs of the procedures, and USD $4,432 for the estimated overall cost per one year of QALY, in chronic persistent low back pain non-responsive to conservative management.

• Journal of Korean Society on Water Environment
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• v.27 no.3
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• pp.349-356
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• 2011

This study, which evaluated the contribution of the real economic value and system in the Nakdong River Basin, estimated the emergy analysis for environmental accounting of the TMDL program. And an environmental accounting for TMDL is evaluated before and after adopting TMDL program respectively. The value of emergy after adopting the TMDL was 7.90 E+20 sej/yr. Although the real yield of the river after governmental investment was high (before: 9.7118 E+20 sej/yr and after: 9.7224 E+20 sej/yr), the effects of improvement was not great, in terms of an investment cost. The benefit/cost ratio resulted from environmental accounting has decreased from 1.493 to 1.230 due to the cost of managing treatment facilities. The method of improving water quality in the Nakdong River Basin by the TMDL program should be changed into an ecological treatment facilities using resources efficiently from a control of water quality depending on expansion of the wastewater treatment facilities and advanced treatment plant using high cost and non-renewable energies.

• Journal of the Korean Society for Heat Treatment
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• v.2 no.3
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• pp.46-54
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• 1989

• The Journal of Korean Medicine
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• v.40 no.3
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• pp.87-98
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• 2019

Objectives: Patients with respiratory diseases are increasing as air pollution due to fine dust gets worse. Diseases that occupy a large proportion of respiratory diseases in medical institutions are acute bronchitis, chronic bronchitis and Allergic rhinitis. The number of patients with all three diseases is gradually increasing. This study was to suggest assignment of medicine policy for improving accessibility to Korean medical treatment of respiratory diseases analyzing the current treatment status of acute bronchitis, Chronic bronchitis and Allergic rhinitis patients in Western medical and Korean medical institutes in this situation. Methods: This study used 2017 National patient sample data from the Korean Health Insurance Review and Assessment Service for research. Acute bronchitis, Chronic bronchitis, Allergic rhinitis was according to KCD code. This research contains Socio-demographic analysis classified by sex and age, the number of three disease's patients. Also the number of medical treatment, the expense of recuperation cost, medical practices were analyzed compare with Western and Korean medicine. Results: The incidence of three diseases is higher among female than male. There are many patients under the age of 10 in the case of acute bronchitis and allergic rhinitis, while there are many patients over 50 years of age in chronic bronchitis. Western medical treatment take up a larger proportion than Korean medical treatment in part of the number of three disease's patients, the number of medical treatment, the expense of recuperation cost. Conclusions: Much more patients of these diseases visit in Western medical clinic and hospital than Korean medical clinic and hospital for treatment. There are many parts of Korean medical treatment that are not covered by Health insurance benefits like herbal decoction, pharmacopuncture, etc. Korean medicine need to do the efforts for expanding medical field in variety. Also it is demanded for institutional support for reduction of the cost burden and improving on accessibility of Korean medical treatment in order to treat with the increase in respiratory diseases due to fine dust.

• Journal of the Society of Naval Architects of Korea
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• v.47 no.2
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• pp.258-264
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• 2010

Various kinds of ballast water treatment systems (BWTS) have been developed corresponding to reinforced IMO rules for marine environment. Some of them got the certificate of IMO and others are waiting for it. Selection of optimum BWTS is very important. Optimum BWTS means not only functional requirements but also economic efficiency. This paper presents economic analysis model for optimum BWTS according to ship type and size. In this study 10 kinds of BWTS whose initial installation cost and maintenance cost are known are analyzed based on present worth method. It is assumed that all BWTS satisfy minimum functional requirements and we need to consider different economical efficiency. Through the economic analysis we could select optimum BWTS.