• 한국독성학회:학술대회논문집
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• 한국독성학회 2003년도 춘계학술대회 논문집
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• pp.57-57
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• 2003

Epidemiological studies of arsenic have shown that chronic exposure to arsenic can result in an increased incidence of cancer of the lung, skin, bladder and liver. It is impossible that the toxicity study of arsenic in the human, we become to measure in vitro cytotoxicity of inorganic and organic arsenic in the human normal liver cells including Chang Liver and WRL. (omitted)

• 한국독성학회:학술대회논문집
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• 한국독성학회 2003년도 춘계학술대회 논문집
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• pp.53-53
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• 2003

Certain chlorinated propanols occur as contaminants in hydrolysed vegetable proteins. Processing of defatted vegetable proteins by traditional hydrochloric acid hydrolysis leads to the formation of 3-monochloro-1, 2-propanediol(3-MCPD). The objective of this study was to determine the toxicity of 3-MCPD in the rat following oral(gavage) administration for 13 weeks. (omitted)

• 한국환경성돌연변이발암원학회:학술대회논문집
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• 한국환경성돌연변이발암원학회 2002년도 Current Trends in Toxicological Sciences
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• pp.71-72
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• 2002

• 한국독성학회:학술대회논문집
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• 한국독성학회 2002년도 Molecular and Cellular Response to Toxic Substances
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• pp.204-204
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• 2002

Alcohol drinking during pregnancy can result in abnormal fetal development including fetal alcohol syndrome (FAS). The molecular mechanisms of FAS, however, is not completely elucidated. In the present study, we evaluated the developmental toxicity of ethanol and its metabolite, acetaldehyde using post implantation whole embryo culture and determined changes of gene expression by ethanol treatment by cDNA microarray.(omitted)

• 한국독성학회:학술대회논문집
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• 한국독성학회 2003년도 추계학술대회
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• pp.181-181
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• 2003

The aims of present study were to compare the effects of in utero exposure of several chemicals which have antiandrogenic characteristics on the development of reproductive organs and to investigate the specific mechanisms related to the abnormalities observed in the male reproductive system.(omitted)

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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• pp.173.1-173.1
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• 2003

The present study was conducted to determine the effects of bis-carboxyethyl germanium sesquioxide(Ge-132) and caffeic acid phenethyl ester(CAPE) on immune system in female BALB/c mice. The mice were orally exposed continuously to Ge-132 (0, 50, 100, or 200mg/kg), or CAPE (0, 5. 10, or 20mg/kg) for 14 days. Immunomodulatory activity was evaluated by assessment of body and organ weight, lymphocytes blastogenesis, (omitted)

• 한국수의병리학회지
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• 제2권1호
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• pp.9-16
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• 1998

Apodemus agrarius Pallas has been known to be a reservoir of hanta virus. But there was no report of immune organs. So this study was performed to clarify the relation between Structure and function of immune organ. In the present investigation an immunocytochemistry procedure was used to examine the distribution of T and B cell and macrophage populations in the thymus spleen and lymph nodes. Most of lymphoid organ showed decreased pattern of Ly1 positive T and IgM positive B cells. Macrophage positive cells were deceased in vivo. The present study gives an overview on the immune organ structure and function of Apodemus agrarius Pallas.

• 한국독성학회:학술대회논문집
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• 한국독성학회 2001년도 International Symposium on Dietary and Medicinal Antimutgens and Anticarcinogens
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• pp.116-117
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• 2001

The phthalates have been shown to produce hepatic peroxisome proliferation and certain peroxisome proliferators (PPs) are also known to increase the incidence of liver tumors in rodents. In this study we investigated the correlation between oxidative injury, changes in peroxisomal and microsomal enzymes and tumor formation in PP-treated rats.(omitted)

• 한국독성학회:학술대회논문집
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• 한국독성학회 2003년도 춘계학술대회 논문집
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• pp.105-106
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• 2003

Diisodecyl phthalate (DIDP) which has high physical flexibility, various colors, low viscosity, high stability is used as coating material in ballon, vinyl ink, tent, textile, home and cars interior design and electric cable. In rodents, DIDP is suspected to be a peroxisome proliferator, a nongenotoxic carcinogen. In this study, we performed the carcinogenicity test of DIDP. (omitted)

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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• pp.99.2-99.2
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• 2003

One of the major limitations in using adenoviral vector for gene therapy is inefficient infection of host cells. The presence of coxsackievirus and adenovirus receptor (CAR) and ${\alpha}$-integrin on cell surfaces is required for efficient adenovirus infection. In this study, we investigated the effect of trichostatin A, a histone deacetylase inhibitor, on transfection efficiency after transduction of adenovirus mediated p16$\^$INK4a/ gene transfer. In our previous study, p16$\^$INK4a/ tumor suppressor gene transfer in the non-small cell lung cancer cells (A549 cells) by transduction of recombinant adenovirus (Ad5CMV-p16) resulted in significant inhibition of cancer cell proliferation. (omitted)