The morphological and functional studies of lymphoid organs in Apodemus agrarius pallas

등줄쥐에서 면역관련 장기의 특성연구

  • Jang, Dong-Deuk (Department of Pathology, National Institute of Toxicological Research, KFDA) ;
  • Lee, Won-Kyu (Department of Pathology, National Institute of Toxicological Research, KFDA) ;
  • Kim, Dae-Jung (Department of Pathology, National Institute of Toxicological Research, KFDA) ;
  • Shin, Dong-Whan (Department of Pathology, National Institute of Toxicological Research, KFDA) ;
  • Hong, Choong-Man (Department of Pathology, National Institute of Toxicological Research, KFDA) ;
  • Yoon, Chang-Yong (Department of Pathology, National Institute of Toxicological Research, KFDA) ;
  • Park, Jin-Soo (Department of Pathology, National Institute of Toxicological Research, KFDA) ;
  • Cho, Jae-Chon (Department of Pathology, National Institute of Toxicological Research, KFDA) ;
  • Bae, Jong-Hee (Department of Veterinary medicine, Cheju National University)
  • 장동덕 (식품의약품안전청 국립독성연구소 병리부) ;
  • 이원규 (식품의약품안전청 국립독성연구소 병리부) ;
  • 김대중 (식품의약품안전청 국립독성연구소 병리부) ;
  • 신동환 (식품의약품안전청 국립독성연구소 병리부) ;
  • 홍충만 (식품의약품안전청 국립독성연구소 병리부) ;
  • 윤창용 (식품의약품안전청 국립독성연구소 병리부) ;
  • 박진수 (식품의약품안전청 국립독성연구소 병리부) ;
  • 조재천 (식품의약품안전청 국립독성연구소 병리부) ;
  • 배종희 (제주대학교 수의학과)
  • Published : 1998.06.01

Abstract

Apodemus agrarius Pallas has been known to be a reservoir of hanta virus. But there was no report of immune organs. So this study was performed to clarify the relation between Structure and function of immune organ. In the present investigation an immunocytochemistry procedure was used to examine the distribution of T and B cell and macrophage populations in the thymus spleen and lymph nodes. Most of lymphoid organ showed decreased pattern of Ly1 positive T and IgM positive B cells. Macrophage positive cells were deceased in vivo. The present study gives an overview on the immune organ structure and function of Apodemus agrarius Pallas.

Keywords