• The Journal of Engineering Geology
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• v.6 no.3
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• pp.111-118
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• 1996

In general, a three dimensional ground behaviour during tunneling is simulated by using two dimensional analysis programs in consideration of a certain ratio of stress or strain distribution to take into account the effect of construction stage by a tunnel face advance. A series of trree dimensional analyses was conducted to deduce a normalized displacement (surface or crown settlement) curve in longitudinal direction, of which curve is reflecting an effect of a tunnel advance under a various condition. And, by using try and error technique, two dimensional analyses were carried out to determine an optimum stress distribution ratio for a settiement curve coincided with the curve obtained by three dimensional analyses. Finally, monitored results from a subway tunnel were compared with two dimensional analysis results for varification of the deduced stress distribution ratio as well as the two dimensional analysis program employed in this study.

• The Transactions of the Korean Institute of Power Electronics
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• v.4 no.6
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• pp.561-569
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• 1999

In this paper, the diode bridge-type ZVT(Zero- Voltage Transition) inverter is proposed. It consists of one a auxiliaI${\gamma}$ switch, three resonant inductors and six blockin당 diodes. So, the main advantage of the proposed t torXJ!ogy is the reduction of the auxiliar${\gamma}$ switch compare to the conventional ZVT inverter. The topology of t the propostxl lVT inverter is analyztxl with a description of the control conditions based on the load current. A And the resonant period control for operating the proposed inverter optimally is discussed by using resonant i inductor current ftxxlback. To verify the proposed topology, the detailed simulation and exJX끼mental results i indicate that zero volta당e operation during transition can be achieved.

• Resources Recycling
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• v.8 no.5
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• pp.28-33
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• 1999

Trus paper presenls a hydrometallurgical process Tor recovcnng ~uckcals mckcl sulfate fiom the spent nickel-cadrnlum bauery in whch c:,dmi~lm war re~novcdb y vapowing m e h d in vacuum. F ~ s ts,e lcct~vcc rushing and classification mell~odw ere performed to separate iron physically and the nickel-rich sample (over 80% nickel) was obtained. Ths sarnple was dissolved in sulf~ uiuica cid to obtain a luckcl sulfatc soluho~d~o se to its seluradon painl. TIE Cree acid in the unpurificd nickcl solut~onw as neutl-dized and iron war ve~novedk om the solulmn Thc mckel sulhte solution was c~yst~llizeadt around 45'C to obtain ruckel sulfate henahyril-ate.

• Journal of Physiology & Pathology in Korean Medicine
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• v.34 no.3
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• pp.136-141
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• 2020

The purpose of this study was to investigate the action mechanism of the roots of Adenophora triphylla var. japonica extract (ATE) in 3T3-L1 adipocytes. Cell toxicity test by MTT assay and lipid accumulation was performed to evaluate the inhibitory effect on the differentiation of adipocyte from preadipocytes induced by MDI differentiation medium, while adipogenesis related proteins expression level were evaluated by western blotting. As a result, ATE inhibited MDI-induced adipocyte differentiation in 3T3-L1 cells dose-dependently without cytotoxicity. Our results showed that ATE inhibited the phosphorylation of IRS1, thereby decreasing the expression of PI3K110α and reducing the phosphorylation of AKT and mTOR, resulting in attenuated protein expression of C/EBPα, PPARγ, ap2 and FAS in 3T3-L1 cells. These results suggest anti-adipogenic functions for ATE, and identified IRS1 as a novel target for ATE in adipogenesis.

• Transactions of the Korean Society of Mechanical Engineers
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• v.11 no.2
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• pp.331-344
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• 1987

A numerical analysis has been conducted on the interaction of the thermal radiation and natural convection in a rectangular enclosure filled with a gray fluid. P-1 approximation is adopted for the radiative transfer and its application limit is examined. Considered are the Stark number effect, the optical thickness effect and the wall emissivity effect on the flow and heat transfer characteristics. As the Stark number increase or the optical thickness decreases, the boundary layer thickness and the flow velocity increase. Transition to turbulence is retarded with the increase of the radiation effect. When the optical thickness is one, the radiation effect is negligible for the Stark numbers larger than 10.

• ALGAE
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• v.24 no.2
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• pp.121-127
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• 2009

The unicellular green alga, Haematococcus pluvialis, accumulates the highest level of astaxanthin among knownastaxanthi.n-producing organisms. Light is the most important factor to induce astaxanthin by H. pluvialis. BIue andred LEDs, whose ${\lambda}_{max}$'s are 470 and 665 nm, respectively, were used for internally illuminated light sources.Fluorescent lamps were also used for both internal and external illumination sources. The astaxanthin levels in thesevarious lighting systems were analyzed and compared each other. The cultures under internally illuminated LEDsaccumulaled 20% more astaxanthin than those under fluorescent lamp. Furthermore, LEDs generated much lessheat than the fluorescent lamps, which gives one more reason for the LEDs being a suitable internal Light source forastaxanthin induction. The results reported here would lead novel designs of photobioreactors with improvementsof illumination methods for high level of astaxanthm production. The maximum astaxanthin concentrations as wellas the astaxanthin yield per supplied photon were increased by at least 20% when blue or red LEDs were supplied.

• Journal of Surface Science and Engineering
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• v.26 no.6
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• pp.291-298
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• 1993

In order to substitute for porous nickel anode in Molten Carbonate Fuel Cell(MCFC), porous cermet elec-trode was fabricated with Ni and Ni-P coated ceramic powder. Ni and Ni-P were coated by electroless plat-ing method in the nickel solution containing of hydrazine and sodium hypophosphate as a reducing agent. The plating solution was stirred by air and mechanical agitator. Ultrasonic irradiation was applied to the plating bath to improved the effect of agitation and coating speed. Electorde was formed by pressing method and doc-tor blade method followed by sinterd at$ 800^{\circ}C$ for 6 hours in H2 environment. Anode performance test carried out by potentiodynamic polarization technique in the MCFC operating condition and 154-161mA/$\textrm{cm}^2$ as ob-tained as a anode current density at the+100mV overpotential.

• Journal of The Geomorphological Association of Korea
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• v.19 no.4
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• pp.39-57
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• 2012

The volcanic edifice of Ulleungdo is largely divided into a shield volcano underwater and a tholoide above seawater. The geological features of the volcano above seawater are basically alkali volcanic rocks that are further divided into five geological strata: agglomerates and tuffs trachyte and phonolite trachytic pumice trachyandesite, and sedimentary layer. The topography of Ulleungdo consists of volcanic landform on the whole, and such volcanic landform is weathered and eroded into various weathering landform, stream landform, coastal landform, structural landform, etc. Major volcanic topography includes caldera basin, central cone, and columnar joint, whereas weathering topography features, tafoni, gnamma, tor, weathered cave, talus, etc. In major coastal topography are sea cliff, wave-cut platform, sea stack, sea arch, sea cave, shingle beach, coastal terrace, etc. For stream topography, its development is minimal except for waterfalls.

• Development and Reproduction
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• v.23 no.2
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• pp.119-128
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• 2019

Melanoma is one of the most aggressive and treatment-resistant malignancies. Antidiabetic drug metformin has been reported to inhibit cell proliferation and metastasis in many cancers, including melanoma. Metformin suppresses the mammalian target of rapamycin (mTOR) and our previous study showed that it also inhibits the activity of extracellular signal-regulated kinase (ERK). Paclitaxel is currently prescribed for treatment of melanoma. However, paclitaxel induced the activation of ERK/mitogen-activated protein kinase (MAPK) pathway, a cell signaling pathway implicated in cell survival and proliferation. Therefore, we reasoned that combined treatment of paclitaxel with metformin could be more effective in the suppression of cell proliferation than treatment of paclitaxel alone. Here, we investigated the combinatory effect of paclitaxel and metformin on the cell survival in SK-MEL-28 melanoma cell line. Our study shows that the combination of paclitaxel and metformin has synergistic effect on cell survival and suppresses the expression of proteins involved in cancer metastasis. These findings suggest that the combination of paclitaxel and metformin can be a possible therapeutic option for treatment of melanoma.

• Computers and Concrete
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• v.16 no.2
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• pp.287-309
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• 2015

FormWorks-Plus is a generalized public domain user-friendly preprocessor developed to facilitate the process of creating finite element models for structural analysis programs. The lack of a graphical user interface in most academic analysis programs forces users to input the structural model information into the standard text files, which is a time-consuming and error-prone process. FormWorks-Plus enables engineers to conveniently set up the finite element model in a graphical environment, eliminating the problems associated with conventional input text files and improving the user's perception of the application. In this paper, a brief overview of the FormWorks-Plus structure is presented, followed by a detailed explanation of the main features of the program. In addition, demonstration is made of the application of FormWorks-Plus in combination with VecTor programs, advanced nonlinear analysis tools for reinforced concrete structures. Finally, aspects relating to the modelling and analysis of three case studies are discussed: a reinforced concrete beam-column joint, a steel-concrete composite shear wall, and a SFRC shear panel. The unique mixed-type frame-membrane modelling procedure implemented in FormWorks-Plus can address the limitations associated with most frame type analyses.