• Journal of Ginseng Research
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• v.15 no.3
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• pp.224-230
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• 1991

The seven traditional quality factors including age and root weight ect. were reviewed in relation to the chemical components as a new quality factor and pharmacological data. The other important factor, production place, appeared to be sum of the eight factors. The important of production place indicated that the best quality ginseng is produced in the optimum environment. The description of ginseng for medicinal use in present materia medica missed most traditional quality factors only indicating the change by processing. Such phenomena do not mean the significant of raw$.$ ginseng quality. since appropriate raw ginseng was supplied in traditional way. For the generation with analytical attitude the description of raw ginseng quality to the processed ginseng products is recommendable. For the quality control with biologically active or index compound, the composition of various compounds seems to be the best. The establishment of physical and chemical quality creteria that will match with the traditional mothod it needed and will accomplished by comparative research on raw ginseng from various production sites and growth conditions. The description of production-place, grade and quantity of raw ginseng to the processed products will give better information and higher popularity of products to consumers.

• Journal of Radiation Protection and Research
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• v.12 no.2
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• pp.37-50
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• 1987

The exposure of the population in the United States to ionizing radiation has recently been evaluated by the National Council on Radiation Protection and Measurements (NCRP). This was done by constituting six organizational groups to address various phases of the work and the results of this work are summarized in this article. The article is based on the report, by the same title, which is scheduled for publication by the NCRP in September, 1987. The six organizational groups are titled Radiation Exposure from Consumer Products, Natural Background Radiation, Radiation Associated with Medical Examinations, Radiation Received by Radiation Employees, Public Exposure from Nuclear Power, and Exposure from Miscellaneous Environmental Sources. These titles are descriptive of the subject areas covered by each of these separate groups. The data evaluated are for the years 1977-1984 with the majority of the data being for the period 1980-1982. Summary information is presented and discussed for the number of people exposed to given sources, the effective dose equivalent, the average effective dose equivalent to the U.S. population, and the genetically significant dose equivalent. The average annual effective dose equivalent from all sources to the U.S. population is approximately 3.6 mSv (360 mrem). Exposures to natural sources make the largest contribution to this total. Radon and radon decay products contribute 2.0 mSv (200 mrem) whereas the other naturally occurring radionuclides contribute 1.0 mSv (100 mrem). Among man-made or enhanced sources, medical exposures make the largest additional contributions, namely 0.39 mSv (39 mrem) for diagnosis and 0.14 mSv (14 mrem) for nuclear medicine. It was not possible to evaluate exposures for therapy. Most of the other sources of population exposure, including nuclear power and consumer products, are minor. A possible exception would be the use of tobacco products. These exposures are discussed in relation to a negligible individual risk level of $10{\mu}Sv/y$ (1 mrem/y). The NCRP considers exposures below the negligible individual risk level as trivial and as such should be dismissed.

• 산업보건소식
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• no.47
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• pp.4-14
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• 1987

The authors investigated estimated amounts of salt intake of workers in manufacturing industries who consisted of 1,506 males in 6 manufacturing fields and 476 females in 3 fields in Pusan area using filter paper method which was developed recently. The obtained results were as follows; 1. Mean excretion amounts of urinary electrolytes were Na 200.7 mEq/l, K 44.2 mEq/l and Cr 1.12g/l in male and Na 190.2 mEq/l, K 44.0 mEq/l and Cr 1.10g/1 in female. 2. Mean daily salt intake amounts were 19.4g in male and l5.3g in female. 3. By the fields of manufacturing industries in male, workers in metal product field had the highest salt intake as 20.0g, and the following were workers in food and tobacco field as 19.7g, workers in textile, wearing apparel and leather field as 19.6g in order. 4. In female, workers in textile, wearing apparel and leather field had the highest salt intake as l5.7g and the next were workers in chemical, coal and rubber products field as l5.0g and workers in fabricated metal products, machinery and equipments as l4.3g, respectively.

• Applied Chemistry for Engineering
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• v.8 no.1
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• pp.8-15
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• 1997

This study was carried out to present a analysis of pyrolytic degradation of 4-hydroxy-3-methoxybenzal dehyde(vanillin) pyrolyzed at $330^{\circ}C{\sim}920^{\circ}C$ by Curie-point pyrolyzer connected with GC/MSD by on-line system. Identified by GC/MSD were 100 pyrolytic products of vanillin. The pyrolysis of the compound gave benzene, phenol, 1,3-cyclopentadiene, methyl benzene, benzaldehyde, benzofuran, and cresol as major products, which were produced by pyrolytic degradation and synthesis of vanillin radicals.

• Korean Journal Plant Pathology
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• v.14 no.6
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• pp.630-635
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• 1998

Tobacco mosaic tobamovirus (TMV), cucumber mosaic cucumovirus (CMV), cucumber green mottle mosaic tobamovirus (CGMMV) and zucchini yellow mosaic potyvirus (ZYMV) from individual fruits and seeds of hot pepper and cucumber were detected by the reverse transcription-polymerase chain reaction (RT-PCR). The dilution end-points for RT-PCR in curde sap from TMV. and CMV - infected hot pepper leaves and CMV - and CGMMV-infected cucumber leaves were 10-5. However, the amount of PCR product obtained from preparation of ZYMV-infected cucumber leaf was 10-fold lower than those of CMV or CGMMV-infected cucumber leaves. In hot pepper, both TMV and CMV were detected in all parts of the fruit wall tissue, but the yields of PCR products in the fruit stalk and its surrounding tissues were higher than those of the end parts of the fruit. On the other hand, in cucumber fruit infected with CMV, CGMMV or ZYMV, the fruit wall tissue and seed located in both stalk and end parts showed higher yields of PCR products than those of intermediate parts. Of five viruses that were analysed, only TMV in hot pepper seed, and CGMMV and CMV in cucumber seed were detected in testa parts.

• Clinical and Experimental Pediatrics
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• v.59 no.12
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• pp.490-493
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• 2016

Electronic cigarettes are novel tobacco products that are frequently used these days. The cartridge contains liquid nicotine and accidental poisoning, even with a small oral dose, endangers children. We present here a mortality case of a 15-month-old child who ingested liquid nicotine mistaking it for cold medicine. When the emergency medical technicians arrived, she was found to have pulseless electrical activity. Spontaneous circulation was restored after approximately 40 minutes of cardiopulmonary resuscitation. The cotinine level in her urine was 1,716 ng/mL. Despite intensive supportive care, severe anoxic brain injury was found on computed tomography and the child ultimately died. This fatality highlights the need for public health efforts to minimize such accidents.

• Journal of Microbiology and Biotechnology
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• v.10 no.2
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• pp.264-266
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• 2000

A new GFP-based T-vector for cloning of PCR products was developed by using a green fluorescent protein (GFP) as a mafker. In order to facilitate the DNA inserts, multiple restriction sites, SP6 and T7 RNA polymerase promoter sites, were introduced close to the PCR DNA insertion site of a pCRGv vector. The XcmI-digested pHNT plasmid can be used to clone a 3' A-overhanged PCR DNA amplified by Taq DNA polymerase. A potential method of easing some difficulties from its use along with its cost savings proveded by this vector are likely to lead to the replacement of other T-vectors for PCR DNA cloning.

• Archives of Pharmacal Research
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• v.6 no.1
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• pp.63-68
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• 1983

The binding properties of three ginsenosides, Rb$_{1}$, Rc and Re, to bovine and human serum albumins have been examined by fluorescence probe technique. 1-anilinonphathalene-8-sulfonate (ANS) was used as the fluorescence probe. Protopanaxatriol glycoside, Re, did not quench the fluorscence of ANS to the bovine serum albumin. Competitive bindings between protopanaxadiol glycosides, Rb$_{1}$ and Rc are both 3.3 . The binding constants for Rb$_{1}$ and Rc with bovine serum albumin were 1.91 * 10$_{4}$M$_{-1}$ AND 1.04 * 10$^{[-994]}$ M$^{-1}$ , respectively. The ginsenosides, Rb$_{1}$, Rc and Re did not quench the fluorescence of ANS bound to human serum albumin.

• Journal of the Korean Society of Tobacco Science
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• v.30 no.1
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• pp.8-13
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• 2008

Several activated carbon in different specific surface area was prepared by steam and chemical activation of coconut shell. Products were characterized by BET ($N_2$) at 77K, and probed to be highly specific surface area of $1580m^2/g$ and pore volume that had increased with activating conditions. And also we have analyzed the adsorption efficiency of vapor phase components in cigarette mainstream smoke in order to evaluate the relationship between thesmoke components and the physicochemical properties of activated carbons. As a result of this study, the delivery of mainstream smoke was directly affected by the specific surface area and the pore size of activated carbon. The activated carbon prepared by steam activation exhibited better adsorption efficiency on the vapor phase components in mainstream smoke compared with activated carbon prepared by $ZnCl_2$, due to the higher micro-pore area of 66%. But the adsorption efficiency of semi-volatile matters such as phenolic components in a main stream smoke by the activated mesoporous carbon prepared by $ZnCl_2$ is more effective. From the these results, we can conclude that specific surface area by the micropore area increased the adsorption efficiency of activated carbon on vapour phase components, but semi-volatiles or particulate matter was affected by the ratio of mesopore area in total specific surface area.

• 한국생물공학회:학술대회논문집
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• 2001.11a
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• pp.193-196
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• 2001

IL-18. formerly known as IGIF(interferon -gamma inducing factor), is structurally IL-l related but functionally IL-12 related pro-inflammatory cytokine. The human IL -18(hIL-lS), like IL-$1{\beta}$, is synthesized as a biologically inactive precursor of 24kDa lacking a signal peptide, and then cleaved into an active mature form by cystein protease IL-$1{\beta}$ converting enzyme (ICE: caspase- 1), We tested if the mature hIL -18 can be expressed and secreted into culture medium by transforming the forming gene construct consisting of a mature hIL-18 gene fused to signal peptide of rice amylase lA. Secondly, we were tested if the pro- IL-18 could be processed into a biologically active form by caspase-l like protease in plant. Cell suspension culture was established from the leaf-derived calli of transgenic tobacco plant. Southern and Northern blot analysis indicated the expression of both pro-hIL-18 and mature hIL-18 plant cells. Western blot analysis introduced the protein products of pro- hIL -18 and mhIL -18 were observed in transigenic cell lines. In addition, the molecular size of recombinant pro-hILl-18 and mhIL-18 were estimated to be 24kDa and 18kDa, respectively. ELISA revealed that the amount of pro- hIL -18 was 1.3ug per gram of fresh weight calli. Moreover, the presence of mhIL-18 was detected in the culture medium and it appeared to be 25ug/L.