• Development and Reproduction
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• v.13 no.3
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• pp.183-190
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• 2009

In mammals, puberty is a dynamic transition process from infertile immature state to fertile adult state. The neuroendocrine aspect of puberty is started with functional activation of hypothalamus-pituitary-gonadal hormone axis. The timing of puberty can be altered by many factors including hormones and/or hormone-like materials, social cues and metabolic signals. For a long time, attainment of a particular body weight or percentage of body fat has been thought as crucial determinant of puberty onset. However, the precise effect of high-fat (HF) diet on the regulation of hypothalamic GnRH neuron during prepubertal period has not been fully elucidated yet. The present study was undertaken to test the effect of a HF diet on the puberty onset and hypothalamic gene expressions in immature female rats. The HF diet (45% energy from fat, HF group) was applied to female rats from weaning to around puberty onset (postnatal days, PND 22-40). Body weight and vaginal opening (VO) were checked daily during the entire feeding period. In the second experiment, all animals were sacrificed on PND 36 to measure the weights of reproductive tissues. Histological studies were performed to assess the effect of HF diet feeding on the structural alterations in the reproductive tissues. To determine the transcriptional changes of reproductive hormone-related genes in hypothalamus, total RNAs were extracted and applied to the semi-quantitative reverse transcription polymerase chain reaction (RT-PCR). Body weights of HF group animals tend to be higher than those of control animals between PND 22 and PND 31, and significant differences were observed PND 32, PND 34, PND 35 and PND 36 (p<0.05). Advanced VO was shown in the HF group (PND $32.8{\pm}0.37$ p<0.001) compared to the control (PND $38.25{\pm}0.25$). The weight of ovaries (p<0.01) and uteri (p<0.05) from HF group animals significantly increased when compared to those from control animals. Corpora lutea were observed in the ovaries from the HF group animals but not in control ovaries. Similarly, hypertrophy of luminal and glandular uterine epithelia was found only in the HF group animals. In the semi-quantitative RT-PCR studies, the transcriptional activities of KiSS-1 in HF group animals were significantly higher than those from the control animals (p<0.001). Likewise, the mRNA levels of GnRH (p<0.05) were significantly elevated in HF group animals. The present study indicated that the feeding HF diet during the post-weaning period activates the upstream modulators of gonadotropin such as GnRH and KiSS-1 in hypothalamus, resulting early onset of puberty in immature female rats.

• KDI Journal of Economic Policy
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• v.35 no.2
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• pp.71-105
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• 2013

Now that fiscal soundness is increasingly important influenced by the euro area fiscal crisis, early budget execution has been under the spotlight as a tool for economy control, other than typical expansionary method, such as supplementary budget. Basically, early budget execution is a fiscal policy instrument that reponses to economic fluctuations through modifying the inter-temporal allocation of fiscal expenditure within budget, without affecting fiscal soundness. This study empirically examines how effective the intert-temporal reallocation of fiscal expenditure is in economy control. Using Korea's Consolidated Fiscal data, the size of inter-temporal reallocation of fiscal expenditure is defined as changes of fiscal expenditure for one year excluding seasonal factors and used to explain real economic growth rate, a dependent variable. The result shows that the macroeconomic effect of the inter-temporal reallocation turns out meaningful in general, though some policy time lag exists. Meanwhile, a simulation using macroeconomic model finds that overall effect on economic growth is not large because increase in fiscal expenditure allocation at a certain point of time is canceled by the opposite direction within the same fiscal year. However, the inter-temporal reallocation is found to reduce volatility of key macroeconomic variables so as to contribute to partially stabilizing macroeconomy. In particular, such effect of economic stabilization seems to be highly apparent at the time of financial crisis, but not very noticeable in normal economic cycle.

• 한국균학회소식:학술대회논문집
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• 2015.11a
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• pp.41-41
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• 2015

Oomycetes belong to the kingdom Straminipila, a remarkably diverse group which includes brown algae and planktonic diatoms, although they have previously been classified under the kingdom Fungi. These organisms have evolved both saprophytic and pathogenic lifestyles, and more than 60% of the known species are pathogens on plants, the majority of which are classified into the order Peronosporales (includes downy mildews, Phytophthora, and Pythium). Recent phylogenetic investigations based on DNA sequences have revealed that the diversity of oomycetes has been largely underestimated. Although morphology is the most valuable criterion for their identification and diversity, morphological species identification is time-consuming and in some groups very difficult, especially for non-taxonomists. DNA barcoding is a fast and reliable tool for identification of species, enabling us to unravel the diversity and distribution of oomycetes. Accurate species determination of plant pathogens is a prerequisite for their control and quarantine, and further for assessing their potential threat to crops. The mitochondrial cox2 gene has been widely used for identification, taxonomy and phylogeny of various oomycete groups. However, recently the cox1 gene was proposed as a DNA barcode marker instead, together with ITS rDNA. To determine which out of cox1 or cox2 is best suited as universal oomycete barcode, we compared these two genes in terms of (1) PCR efficiency for 31 representative genera, as well as for historic herbarium specimens, and (2) in terms of sequence polymorphism, intra- and interspecific divergence. The primer sets for cox2 successfully amplified all oomycete genera tested, while cox1 failed to amplify three genera. In addition, cox2 exhibited higher PCR efficiency for historic herbarium specimens, providing easier access to barcoding type material. In addition, cox2 yielded higher species identification success, with higher interspecific and lower intraspecific divergences than cox1. Therefore, cox2 is suggested as a partner DNA barcode along with ITS rDNA instead of cox1. Including the two barcoding markers, ITS rDNA and cox2 mtDNA, the multi-locus phylogenetic analyses were performed to resolve two complex clades, Bremia lactucae (lettuce downy mildew) and Peronospora effuse (spinach downy mildew) at the species level and to infer evolutionary relationships within them. The approaches discriminated all currently accepted species and revealed several previously unrecognized lineages, which are specific to a host genus or species. The sequence polymorphisms were useful to develop a real-time quantitative PCR (qPCR) assay for detection of airborne inoculum of B. lactucae and P. effusa. Specificity tests revealed that the qPCR assay is specific for detection of each species. This assay is sensitive, enabling detection of very low levels of inoculum that may be present in the field. Early detection of the pathogen, coupled with knowledge of other factors that favor downy mildew outbreaks, may enable disease forecasting for judicious timing of fungicide applications.

• Korea journal of population studies
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• v.34 no.1
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• pp.53-72
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• 2011

This study analyzes the effects of life course events and labor market conditions on the duration of career interruption among Korean women. The data were drawn from 'A Survey on the Women's Employment Interruption in Korea' conducted by the Korean Ministry of Gender Equality in 2009(currently the Korean Ministry of Gender Equality and Family). This study categorizes the duration of career interruption into three categories: (1) short term interruption(less than 12months), (2) short-medium term interruptio(12-35 months), (3) intermediate term interruption(36-59 months), (4) long term interruption(longer than 36 months), and then analyzes how demographic factors, labor market condition, and life events shape the timing of re-entry into the labor market among women. According to the findings, the jobs that are conducive to combining market work and mother's role expedite women's return to the labor market. Further, the younger, higher the level of human capital, and higher monthly wages that women earned before leaving the labor market, women are likely to experience short-term interruption(less than 12 months) rather than long-term interruption(longer than 60 months). Women who left from the labor market to care for kids are also likely to return to the labor market. However, women who have preschoolers are likely to experience long-term career interruption. These findings highlight the role of family supportive culture at the workplace in order for women to continue their employment while intensive family formation period. Furthermore, the finding that the discriminatory practices against women, in particular mother workers at the workplace lead women to exit from the market work calls for attention to establish family friendly workplace.

• Journal of Digital Contents Society
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• v.19 no.7
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• pp.1365-1372
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• 2018

The purpose of this study is to analyze the importance of the determinants of housing sales agency's role in the sale of apartment housing. For this purpose, a hierarchical decision model was constructed to understand the role and importance of the sales agency. The analytical variable items structured by the research model were set up through literature review, precedent research, and expert brainstorming. The questionnaire consisted of two comparisons for AHP analysis and the importance of absolute importance for fuzzy analysis. Afterwards, the work of correcting the importance was carried out. As a result of the analysis, it was found that the contractor prioritized the sale conditions and the sales agency had priority over the planning for the sale. As a result of analysis, planning of customer pre-sale counseling data, planning of client subscription and contract maximization plan, planning method of advertisement public media method were found to be the most important factors. The results of measurement of absolute importance(fuzzy) & relative importance(,AHP) showed similar tendency. Therefore, it can be seen that the timing of the model house operation is an important period in which the subscription rate depends on the role of the sales agency and the marketing strategy.

• Journal of Service Research and Studies
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• v.10 no.3
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• pp.81-101
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• 2020

Humanity has reached the age of service economy. A new economy requires new management. The chief executive of new management is the CEO. The results of management decision-making are reflected in the company's performance, and are the basis for future growth engines. This study empirically analyzed the effect of CEO competence, corporate orientation, and management performance of small and medium-sized mid-sized business managers on each other. In the study, a hypothesis was established between eight variables. In addition, the relationship between corporate orientation and CEO competency, which has not been studied, was also identified. Set personal effectiveness, willingness to innovate, opportunity recognition, information perception, relationship formation, business management, leadership, organizational culture, and human resource management as measures of CEO competency. After defining the operation in accordance with this study, the analysis was conducted. As a result of the analysis, corporate orientation did not produce a meaningful result in management performance. And CEO competency showed a positive (+) effect on management performance. It can be judged that the CEO variable, a management variable, had a positive effect on management performance. Also, there was a significant result in the relationship between corporate orientation and CEO competency. Innovativeness, initiative, and risk-taking have positive implications for CEO competency. Lastly, corporate orientation showed statistically significant results on management performance through the mediation of CEO competency. It is worth noting the results of this study in that the time of the study was the timing of the global pandemic (fendermic) of the COVID19 virus. In the future, in-depth research is needed on the relationship between CEO-related factors and management performance in a more changed economic environment.

• The Korean Journal of Quaternary Research
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• v.25 no.1
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• pp.15-30
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• 2011

Three sediment cores from two different locations (UJ-03 and UJ-12 cores of valley sediment in Paju area, and CL-4 core of wetland sediment in Cheollipo area) along the western Korean Peninsula yield crucial information on the timing and spatial pattern of century-scale climate changes and subsequent surficial responses during the Holocene. In Paju area, the sediments included abundant coarse-grained sediment (coarse sands and pebbles) from 7100 to 5000 cal. yrBP, total organic carbon (TOC) values showed a marked increase from 5000 to 2200 cal. yrBP, several intermittent depositional layers were observed from 2200 cal. yrBP. In Cheollipo area, lake environment developed from 7360 to 5000 cal. yrBP, the deposition of organic materials increased from 5000 to 2600 cal. yrBP, peatland formed from 2600 cal. yrBP. The two patterns of surficial responses to the climate changes through the Holocene are different to each other. This might be due to the dissimilarity in geomorphic conditions. However, the approximate simultaneity of environmental changes in two areas shows that they both can be correlated to the major climate changes. Two areas which have undergone significant changes indicated that the hydrological factors including precipitation and strength of water flow were most responsible for the landscape and geomorphic evolutions. Although the upwards trend in relative sea-level also played a primary role for environmental changes in coastal area (Cheollipo area), detailed studies have still to be undertaken.

• The Korean Journal of Pesticide Science
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• v.7 no.3
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• pp.223-227
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• 2003

Survey on plant diseases occurring on cucumber cultivated in plastic film house of experimental farm in Suwon was conducted. Through the survey, occurrence of damping-off, downey mildew, powdery mildew and Fusarium wilt was observed. Especially downey mildew caused by Pseudoperonospora cubensis was the most severe foliar disease of cucumber. To control the disease effectively, effects of installation of ventilation fan and optimal spray timing of a chemical, dimethomorph+copper oxychloride WP, were investigated. Two ventilation fans installed at the front and at the back of plastic film house reduced air relative humidity by about 6.4% and downey mildew incidence by 55.7%. Downey mildew incidence on cucumber from untreated chemicals plot in plastic film house installed with ventilation fan was on a equal level with that from treated chemicals plot with three times application of dimethomorph+copper oxychloride WP in plastic film house without ventilation fan. Meanwhile in order to select optimal chemical application time, dimethomorth+copper oxychloride WP was treated three times at 7 days-interval from three days before the disease occurred, right after the disease occurred, and two days after the disease occurred, respectively. The result showed that dimethomorth+copper oxychloride WP applied to cucumber leaves and stems from three days prior to, right after, two days after occurrence of downey mildew reduced downey mildew incidence by 72.9, 61.8, and 23.7%, respectively. The above results showed that regulation of environmental factors like air relative humidity and preventive application of chemicals should be considered to establish control strategy to downey mildew.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.11 no.3
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• pp.866-872
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• 2010

In this paper, we developed a digital soldering station based on PID controller, which supply stable power by controlling the current of heater of soldering iron. The proposed system designed PID controller to converge quickly to the set up temperature by user, and regain the lost of heat by external factors quickly. PID controller, designed by Ziegler-Nichols' tuning method, decides triac's trigger timing using setting temperature and present temperature to control the phase of AC 24V power that supply to the heater. Also, we give the function that shows present temperature and setting temperature of iron, and working time by graphic LCD. And during the rest time, we decided the power saving and extension of iron tip by dropping to the optimal temperature. Two experiments had implemented in $25^{\circ}C$ laboratory to confirm the performance of proposed method. The first experiment took 12sec, 13sec, 16sec, 18sec, reaching to $200^{\circ}C$, $300^{\circ}C$, $400^{\circ}C$, $480^{\circ}C$ respectively which result showed shorten of rising time than previous method. In the loading experiment of $300^{\circ}C$, $400^{\circ}C$, $480^{\circ}C$ steady state showed temperature drop of $3.8^{\circ}C$, $4.1^{\circ}C$, $4.5^{\circ}C$ which result showed the low temperature deviation than previous method.

• Korean Journal of Ecology and Environment
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• v.49 no.4
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• pp.258-270
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• 2016

This study was conducted to test the green-tide mitigation technique in the lower part of the Sook Stream (Chusori) of Daecheong Reservoir from June 27 to August 24, 2014. And the effects were compared with weekly monitoring result of the watching station of the algae alert system (AAS) as well as test beds reach. The green-tide in a test bed was begun from the upstream, and it was gradually transferred and spread toward the downstream by the hydrological factors. The total amount of algae removed by algae removal device during the test period was 33,920 kg, and solids dewatered by natural gravity was 8,480 kg. Also chlorophyll-a content was 2.83 kg, the number of blue-green algae cells was equivalent to $78.6{\times}10^{14}$ cells. Compared with the results of the watching station of AAS, the pre-concentrate removal work in the outbreak waters was able to suggest the possibility of green-tide mitigation. In addition, an effective management of the green-tide was required spatial and temporal occurrence information and practical device technology. Particularly, the optimal timing of algae removal in the river-reservoir hybrid system was recommended at times before the monsoon rainy season and reached the lowest water level.