• Asian-Australasian Journal of Animal Sciences
• /
• 제20권5호
• /
• pp.706-710
• /
• 2007

This study was to investigate the caponization effects on bone characteristics in male chickens, and the optimum testosterone implantation dosage on bone characteristics improvement. Healthy Single Comb White Leghorn cockerels were caponized at 12-wk-old and selected at 16-wk-old for a 10-wk feeding experiment. Fifteen intact male and caponized male chickens (capon) respectively were assigned to trial 1. Ten sham-operated chickens and 40 capons (randomly allocated into four treatments) were implanted with cholesterol (1.62 mm i.d., 3.16 mm o.d., $9.24{\pm}0.36$ mg), low (1 mm i.d., 3 mm o.d., $5.88{\pm}0.23$ mg), medium (1.62 mm i.d., 3.16 mm o.d., $9.81{\pm}0.17$ mg) or high dose (2 mm i.d., 4 mm o.d., $16.7{\pm}0.24$ mg) of testosterone in trial 2. The results from trial 1 showed that the tibia length, relative tibia weight, breaking strength, bending moment and stress in intact males were higher than capons (p<0.05). The blood phosphorus concentration in capons was higher than the intact male chickens (p<0.05). Caponization also resulted in more antrums and osteoclasts within periosteum and cortical bone from histological observation. In trial 2, the adverse impact of caponization on the bone breaking strength, bending moment and stress could be alleviated through medium dose testosterone implantation. It appears that caponization reduced androgen secretion hence influenced the biomechanical characteristics of bone (tibia) and these adverse effects could be alleviated through appropriate dose of testosterone implantation.

• Archives of Reconstructive Microsurgery
• /
• 제6권1호
• /
• pp.63-72
• /
• 1997

We have evaluated the clinical results following the 46 cases of free vascularized osteocutaneous fibular flap transfer to the tibial defect combined with skin and soft tissue defect, which were performed from May 1982 to January 1997. Regarding to the operation, flap size, length of the grafted fibula, anastomosed vessels, ischemic time of the flap and total operation time were measured. After the operation, time to union of grafted fibula and the amount of hypertrophy of grafted fibula were periodically measured through the serial X-ray follow-up and also the complications and results of treatment were evaluated. In the 46 consecutive procedures of free vascularized osteocutaneous fibular flap transfer, initial bony union were obtained in the 43 grafted fibulas at average 3.75 months after the operation. There were 2 cases in delayed unions and 1 in nonunion. 44 cutaneous flaps among the 46 cases were survived but 2 cases were necrotized due to deep infection and venous insufficiency. One necrotized flap was treated with latissimus dorsi free flap transfer and the other was treated with soleus muscle rotational flap. Grafted fibulas have been hypertrophied during the follow-up periods. The fracture of grafted fibula(15 cases) was the most common complication and occurred at average 9.7 months after the operation. The fractured fibulas were treated with the cast immobilization or internal fixation with conventional cancellous bone graft. In the cases of tibia and fibula fracture at recipient site, the initial rigid fixation for the fibula fracture at recipient site could prevent the fracture of grafted fibula to the tibia.

• 대한예방한의학회지
• /
• 제7권2호
• /
• pp.23-33
• /
• 2003

In order to study effects of Yukmiziwhang-Whan on the growth of rats, we divided the experimental rats into two groups(Control&Sample groups) and peformed the experimental study. Sample group was administered the extract of Yukmiziwhang-Whan 1.6ml/100g for 4 weeks, and Control group was administered equal dose of normal saline. We measured the body weight, the length of femur and tibia, the level of serum growth hormone, T3, T4, Insulin and testosterone. The results are summarized as follows : 1) The body weight was not changed compared with Control group. 2) The lengths of femur and tibia in the Sample group was longer than that of Control group, but it was not statistically significant. 3) The level of serum growth hormone in the Sample group significantly increased compared with Control group(p<0.05). 4) The level of serum T3 in the Sample group significantly increased compared with Control group(p<0.05) and T4 level was trending toward increasing compared with Control group. 5) The level of serum insulin in the Sample group was trending toward increase compared with Control group. 6) The level of serum testosterone in the Sample group was trending toward decrease compared with Control group. According to the above experimental results, ${\ulcorner}Yukmiziwhang-Whan{\lrcorner}$ are assumed to have effective activity on the growth of rats.

• 한국산업보건학회지
• /
• 제29권2호
• /
• pp.195-207
• /
• 2019

Objectives: This study was performed to confirm whether plasma lead can be used as a chronic biomarker for the biological monitoring of exposure to lead. Methods: Lead concentrations in 66 plasma samples from retired lead workers (G.M. 60.25 years, Median 61.00 years) and 42 plasma samples from the general population (G.M. 53.76 years, Median 56.50 years) were measured using ICP/Mass. Tibia, whole blood, hemoglobin, hematocrit, and blood zinc protophorphyrin (ZPP) concentrations and urinary ${\delta}$-aminolevulinic acid (${\delta}-ALA$) were measured for correlation analysis with plasma lead. Results: The geometric mean concentration of lead in plasma was $0.23{\mu}g/L$ for the retired lead workers and $0.10{\mu}g/L$ for the general population sample. A simple correlation analysis of biomarkers showed that plasma lead concentration among the retired lead workers was highly correlated with lead concentration in the tibia and with blood lead concentration, and the plasma lead concentration among the general population correlated with ZPP concentration in the blood. The lead concentration in the tibia and the lead concentration in the whole blood increased with length of working period. As the period in the lead workplace increased, the ratio of lead in plasma to lead concentration in whole blood decreased. Conclusion: This study confirmed the possibility of a chronic biomarker of lead concentration in blood plasma as a biomarker. In the future, comparative studies with specific indicators will lead to more fruitful results.

• 한국전문물리치료학회지
• /
• 제3권2호
• /
• pp.36-41
• /
• 1996

The purpose of this study was to determine whether the biomechanical variables of the walking patterns of the obese children compared with those of normal children would revealing significant differences. Normal(N=25) and obese(N=19) subjects were screened based on a health record which was examined to eliminate any subjects who had any pathological condition related to their gait. Data for a minimum of 5 repeated walking trials were collected using a stop watch and a tape measure. Basic kinematic analyses yielded data based on the following variables : stride length divided by leg length, and cadence divided by leg length. This measurement data was classified by the Obesity Index calculated from by height, weight data. Results showed no significant difference among normal, obese and subjects(p>.05). Difficulties in formulating the experimental condition and poor equipment quality are thought to be reason for the inconclusive results. Future studies might include medical complications such as tibia vara, genu valgum, other diseases caused by obesity.

• Archives of Reconstructive Microsurgery
• /
• 제11권1호
• /
• pp.1-10
• /
• 2002

Purpose : To analyze the clinical results of free vascularized osteocutaneous fibula graft to tibial defect combined with soft tissue defect and infection. Materials and Methods : In the retrospective study of 51 consecutive cases of vascularized osteocutaneous fibular graft, the length of the grafted fibula, size of the skin flap, anastomosed vessels, ischemic time of the flap, time for union, hypertrophy of fibula and the complications were evaluated. Results : Initial bony union of the grafted fibula was obtained at 3.74 months after operation, except 4 cases of nonunion and delayed union. The weight bearing without external supports was possible at 18 months after operation in average. The fracture of grafted fibula was most common complication(16 cases). Conclusion : The vascularized osteocutaneous fibula graft provided satisfactory bony union and functional results in the cases not responsible for conventional treatment methods.

• 대한기계학회논문집A
• /
• 제27권12호
• /
• pp.2019-2027
• /
• 2003

Pitting wear is a dominant from of polyethylene surface damage in total knee replacements, and may originate from surface cracks that propagate under repeated tribological contact. In this study, stress intensity factors, K$\_$I/and $_{4}$, were calculated for a surface crack in a polyethylene-CoCr-bone system under the rolling and/or sliding contact pressures. Crack length and load location were considered in determination of probable crack propagation mechanisms and fracture modes. Positive K$\_$I/ values were obtained for shorter cracks in rolling contact and for all crack lengths when the sliding load was apart from the crack. $_{4}$ was the greatest when the load was directly adjacent to the crack (g/a=${\pm}$1). Sliding friction caused a substantial increase of both K$\_$I/$\^$max/ and $_{4}$$\^$max/. The effective Mode I stress intensity factors, K$\_$eff/, were the greatest at g/a=${\pm}$1, showing the significance of high shear stresses generated by loads adjacent to surface cracks. Such behavior of K$\_$eff/ suggests mechanisms for surface pitting by which surface cracks may propagate along their original plane under repeated rolling or sliding contact.

• 대한기계학회:학술대회논문집
• /
• 대한기계학회 2003년도 추계학술대회
• /
• pp.1222-1227
• /
• 2003

Pitting wear is a dominant form of polyethylene surface damage in total knee replacements, and may originate from surface cracks that propagate under repeated tribological contact. In this study, stress intensity factors, $K_{I}$ and $K_{II}$, were calculated for a surface crack in a polyethylene - CoCr - bone system under the rolling and/or sliding contact pressures. Crack length and load location were considered in determination of probable crack propagation mechanisms and fracture modes. Positive $K_{I}$ values were obtained for shorter cracks in rolling contact and for all crack lengths when the sliding load was apart from the crack. $K_{II}$, was the greatest when the load was directly adjacent to the crack $(g/a={\pm}1)$. Sliding friction caused a substantial increase of both $K_{I}^{max}$ and $K_{II}^{max}$. The effective Mode I stress intensity factors, $K_{eff}$, were the greatest at $g/a={\pm}1$, showing the significance of high shear stresses generated by loads adjacent to surface cracks. Such behavior of $K_{eff}$ suggests mechanisms for surface pitting by which surface cracks may propagate along their original plane under repeated rolling or sliding contact.

• Archives of Plastic Surgery
• /
• 제45권1호
• /
• pp.85-88
• /
• 2018

Local flaps exhibit excellent color matching that no other type of flap can compete with. Moreover, surgery using a local flap is easier and faster than surgery using a distant or free flap. However, local flaps can be much more difficult to design. We designed 2 templates to plan a V-Y rotation advancement flap. The template for a unilateral V-Y rotation advancement flap was used on the face (n=5), anterior tibia (n=1), posterior axilla (n=1), ischium (n=1), and trochanter (n=2). The template for a bilateral flap was used on the sacrum (n=8), arm (n=1), and anterior tibia (n=1). The causes of the defects were meningocele (n=3), a decubitus ulcer (n=5), pilonidal sinus (n=3), and skin tumor excision (n=10). The meningocele patients were younger than 8 days. The mean age of the adult patients was 50.4 years (range, 19-80 years). All the donor areas of the flaps were closed primarily. None of the patients experienced wound dehiscence or partial/total flap necrosis. The templates guided surgeons regarding the length and the placement of the incision for a V-Y rotation advancement flap according to the size of the wound. In addition, they could be used for the training of residents.

• Asian-Australasian Journal of Animal Sciences
• /
• 제27권1호
• /
• pp.140-146
• /
• 2014

This experiment aimed to evaluate the effects of different housing systems on behavioral activities, welfare and meat quality of fast-growing broilers. Two hundred broilers were allocated into two housing systems: indoor housing vs indoor with outdoor access. Their general behavior (feeding, drinking, fighting, standing, lying, walking, investigating, dust-bathing and preening) was observed, and tonic immobility, fluctuating asymmetry of legs and wings were measured, and meat quality was analyzed. The results showed that the indoor-housed broilers with outdoor access had significant higher standing, walking, investigating, dust-bathing and preening than those indoor only. However, farming system was not found to significantly affect their feeding, drinking and fighting activities (p>0.05). The value of FA of tibia length of the broilers with outdoor access was significantly lower than that of the indoor-housed birds ($1.57{\pm}1.30$ vs $2.76{\pm}1.40$, p<0.05), while no difference was found for the value of FA in tibia diameter and wing length (p>0.05). TI of the broilers with outdoor access was 165.5 that was significantly higher than that (147.2) of the indoor birds (p<0.05). However, death rate in the outdoor run groups was significantly higher than that of the indoor ones ($2.0{\pm}0.81$ vs $4.0{\pm}0.82$, p<0.05). Meat quality was not affected by the two farming systems. It can be concluded that the results of this study may suggest that the indoor housing with outdoor access provides enriched environment for broilers and facilitates the expression of natural behaviors of the broilers but resulted in poorer performance and higher death rate.