• The Journal of Korean Institute of Communications and Information Sciences
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• v.40 no.5
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• pp.871-885
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• 2015

The improved DFSA for 2.4GHz multi-tags active RFID is suggested in 2 different ways: 1) simplified tag collection and Ack procedure using query command and 2) modified Schoute's method to control the number of slots in the frame. To evaluate the performance of the improved system we develop the simulation model. Varying the number of tags in the system we track the performance measures such as throughput, recognition time for multi-tags and tag recognition rate during a given time. The suggested method shows the best performance over all measures. Simplification of collection and Ack commands using query commands contributes to reducing tag recognition time. And the modified Schoute's method which controls the frame size using $k_1$ and $k_2$ contributes to throughput improvement and reduces target cognition time by reducing the number of collection rounds.

• Journal of Pharmaceutical Investigation
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• v.30 no.3
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• pp.191-199
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• 2000

Genomics is providing targets faster than we can validate them and combinatorial chemistry is providing new chemical entities faster than we can screen them. Historically, the drug discovery cascade has been established as a sequential process initiated with a potency screening against a selected biological target. In this sequential process, pharmacokinetics was often regarded as a low-throughput activity. Typically, limited pharmacokinetics studies would be conducted prior to acceptance of a compound for safety evaluation and, as a result, compounds often failed to reach a clinical testing due to unfavorable pharmacokinetic characteristics. A new paradigm in drug discovery has emerged in which the entire sample collection is rapidly screened using robotized high-throughput assays at the outset of the program. Higher-throughput pharmacokinetics (HTPK) is being achieved through introduction of new techniques, including automation for sample preparation and new experimental approaches. A number of in vitro and in vivo methods are being developed for the HTPK. In vitro studies, in which many cell lines are used to screen absorption and metabolism, are generally faster than in vivo screening, and, in this sense, in vitro screening is often considered as a real HTPK. Despite the elegance of the in vitro models, however, in vivo screenings are always essential for the final confirmation. Among these in vivo methods, cassette dosing technique, is believed the methods that is applicable in the screening of pharmacokinetics of many compounds at a time. The widespread use of liquid chromatography (LC) interfaced to mass spectrometry (MS) or tandem mass spectrometry (MS/MS) allowed the feasibility of the cassette dosing technique. Another approach to increase the throughput of in vivo screening of pharmacokinetics is to reduce the number of sample analysis. Two common approaches are used for this purpose. First, samples from identical study designs but that contain different drug candidate can be pooled to produce single set of samples, thus, reducing sample to be analyzed. Second, for a single test compound, serial plasma samples can be pooled to produce a single composite sample for analysis. In this review, we validated the issue whether the second method can be applied to practical screening of in vivo pharmacokinetics using data from seven of our previous bioequivalence studies. For a given drug, equally spaced serial plasma samples were pooled to achieve a 'Pooled Concentration' for the drug. An area under the plasma drug concentration-time curve (AUC) was then calculated theoretically using the pooled concentration and the predicted AUC value was statistically compared with the traditionally calculated AUC value. The comparison revealed that the sample pooling method generated reasonably accurate AUC values when compared with those obtained by the traditional approach. It is especially noteworthy that the accuracy was obtained by the analysis of only one sample instead of analyses of a number of samples that necessitates a significant man-power and time. Thus, we propose the sample pooling method as an alternative to in vivo pharmacokinetic approach in the selection potential lead(s) from combinatorial libraries.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.11 no.3
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• pp.235-240
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• 2018

FTN method which transmits signals faster the Nyquist rate is representative method for improving throughput efficiency sacrificed performance due to inter-symbol interference. To compensate performance loss, in this paper, we propose a multiband FTN method which split the coded bits into several bands and transmits signals applying FTN method. As coded bits are being assigned different bands, number of samples per bit of each band is increased, it induced performance improvement by noise averaging effect. In the simulations, compared the performance of single band FTN method and multiband FTN method when the interference rate is 25%. The results of simulation show the performance of proposed method is better than that of single band FTN one by 0.3dB~0.5dB.

• Proceedings of the Korean Vacuum Society Conference
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• 2010.02a
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• pp.335-335
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• 2010

한국표준과학연구원 진공센터에서는 국제규격에 바탕을 둔 저진공펌프 종합특성평가시스템을 구축하여 $1100mbar\;{\sim}\;10^{-3}mbar$ 압력 영역에서의 저진공펌프(roots, dry 등)류의 종합특성평가를 시행하고 있다. 저진공펌프 종합특성평가시스템은 국제적 절차에 따른 신뢰성을 바탕으로 구축하고 있으나, 한국표준과학연구원 진공센터 뿐만 아니라, 국내에서도 고진공 종합특성평가 시스템을 구축 하고 있지 않다. 이에 반도체/디스플레이 등 첨단 공정에서 진공 환경을 조성하는 핵심장비인 고진공펌프의 종합특성평가시스템을 개발하고자 터보펌프(TMP) 1000L/s 급의 database를 구축 하였다. 터보펌프(TMP)는 throughput method와 orifice method 두 가지 방법을 병행하여 pumping speed 측정한다. orifice method는 일종의 미세유량 측정 장치이며, 실험값과 계산값 유량의 오차 범위가 작고 신뢰성을 확보하면 throughput method 만으로 측정할 수 있다. Througput method는 $10^{-6}mbar$ 압력 이상의 영역을 측정하며, ultimate pressure 및 $150^{\circ}C$의 bake-out 을 진행하여 base pressure을 측정 할 수 있으며, $10^{-6}mbar$ 압력 이상의 pumping speed를 측정 할 수 있다. 이에 따른 정압형 유량시스템을 개발 중에 있으며, inlet pressure와 outlet pressure를 이용한 compression ratio를 측정 한다. Orifice method는 ultimate pressure와 base pressure을 측정하며, leak valve를 이용한 컨덕턴스(C)로 pressure ratio을 이용하여 유량값을 계산하며, $10^{-6}mbar$ 압력 이하의 pumping speed를 측정할 수 있다. 또한 throughput method와 orifice method의 pumping speed 뿐만 아니라 소비전력 및 소음, 진동, 온도 등 특성평가 관련 사항들의 전반적인 사항을 평가하여 터보펌프(TMP) 1000L/s 급의 database를 구축한다. 향후 예비 실험을 통한 고진공펌프의 종합특성평가시스템을 완비해 나가며, 고진공펌프 종합 특성평가시스템을 통하여 국제적으로 공인받을 수 있는 평가기준을 확립하고 그 기준에 의한 진공/기계적 성능의 전방위적인 종합특성진단과 공정대응성 평가 등 국제적 기술 신뢰성을 확보하고자 한다.

• Journal of Korean Society of Transportation
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• v.24 no.7 s.93
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• pp.115-128
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• 2006

The analytic methodology of a merging area in KHCM(2004) supposes that congestion nay occur when traffic demand is more than capacity However, in many cases, congestion on merging area occurs when summation of traffic demand of main line and ramp is less than capacity, and in present methodology analysis of how main line and ramp flow effect on congestion occurrence is difficult. In this study, the model that is able to estimate traffic flow condition on merging area in accordance with the combination of main line and ramp demand flow is developed. Main characteristic of the model is estimation of maximum possible throughput rate and maximum throughput rate according to the combination of main line and ramp demand flow. Through the estimation of maximum possible throughput rate and maximum throughput rate. it was Possible to predict whether congestion would occur or not and how much maximum throughput rate and congestion would be on merging area. On one hand, in present LOS evaluation methodology on merging area, congestion state is determined as un-congested flow if demand flow is less than capacity. Therefore, to establish more reasonable In evaluation method, new criterion of LOS evaluation on merging area was searched based on the model of this study.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.35 no.10
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• pp.940-947
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• 2007

For the performance upgrade of a supersonic jet fighter, the processor and FLCC(Flight Control Computer) Architecture were upgraded from a baseline FLCC. Prior to the hardware implementation phase, the exact CPU throughput estimation is necessary. For this purpose, an experimental method for new FLCC throughput estimation was introduced in this study.　While baseline FLCC operating, the CPU address bus was collected with logic analyzer, and then decoded to get the exact access times to each memory-memory and the number of program Instruction branches. Based on these data, a throughput test in CPU demo-board of the new FLCC configuration was performed. From test results, the CPU-Memory architecture was design-changed before FLCC hardware implementation phase. To check the flight stability degradation due to power-interrupt problem due to CPU-Memory architecture change, the piloted HILS (Hardware-In-the Loop Simulator) test was conducted.

• Journal of Korean Society of Transportation
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• v.24 no.4 s.90
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• pp.129-148
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• 2006

The objective of this thesis is to develop a capacity analysis and to develop a methodology to evaluate Level of Service over the entire freeway sections by single MOE (Measure of Effectiveness) This study set forth from a following viewpoint. to analyze entire freeway sections as freeway facility system, it is important to identify the exact point where congestion would occur and the extent of the congestion. Therefore, in this thesis, congestion mechanism on freeways was figured out and congestion analysis methodology was developed. Thereby maximum possible throughput rate and maximum throughput rate in bottleneck sections were calculated and a congestion analysis was carried out. The difference between the new method and existing Procedures is that maximum possible throughput rate and maximum throughput rate. that can be considered as capacities of un-congested and congested flow in the bottleneck section, are variable capacities dependent on demand flow.

• ETRI Journal
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• v.31 no.5
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• pp.510-517
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• 2009

A high throughput parallel decoding method is developed for context-based adaptive variable length codes. In this paper, several new design ideas are devised and implemented for scalable parallel processing, a reduction in area, and a reduction in power requirements. First, simplified logical operations instead of memory lookups are used for parallel processing. Second, the codes are grouped based on their lengths for efficient logical operation. Third, up to M bits of the input stream can be analyzed simultaneously. For comparison, we designed a logical-operation-based parallel decoder for M=8 and a conventional parallel decoder. High-speed parallel decoding becomes possible with our method. In addition, for similar decoding rates (1.57 codes/cycle for M=8), our new approach uses 46% less chip area than the conventional method.

• Journal of Digital Convergence
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• v.10 no.9
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• pp.369-374
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• 2012

In this paper, the effective transmission method is proposed to save the energy and to increase the throughput of the communication system using adaptive modulation. Traditionally, adaptive modulation has been used to improve the throughput using the power margin of the system design. Considering the instantaneous energy during the modulation method changing duration, the effective transmission method is proposed. By the simulation, the performance and effectiveness is validated.

• Journal of Environmental Science International
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• v.6 no.2
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• pp.183-187
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• 1997

Organophosphate pesticides were extracted with 70% acetone and then transferred to dichloromethane. Extracts were applied to open-column chromatography with florisil. The florial extract was analyzed by gas chromatography with nitrogen-phosphorus detector(GC/NPD). Recoveries of the 18 organophosphate pesticides were ranged from 88.7% to 100. 0% for the narrow-bore capillary GC(Ultra-21. The minimum detectable level of this analytical method was 0.019 - 0.035 mg/kg. Sample throughput(extraction, open-column chro- matography, and GC analysts) was decreased considerably (8h per sample).