• 재활치료과학
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• 제4권1호
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• pp.39-51
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• 2015

목적 : 본 연구의 목적은 뇌졸중 환자의 삶의 질에 영향을 끼치는 잠재적인 요인들을 체계적인 고찰을 통해 알아보고자 하였다. 연구방법 : 국회도서관, 과학기술정보통합서비스, 학술연구정보서비스, 한국의학논문데이터베이스를 통해 문헌을 검색하였다. 검색 용어는 뇌졸중, 삶의 질, 상관관계였고 한국어로 출판된 연구만을 포함하였다. 결과 : 총 256편의 연구가 검색되었고 그 중 12편의 연구가 본 주제와 부합하여 분석되었다. 분석된 12편의 연구는 모두 비 실험적 연구였고 상관관계 논문이었다. 삶의 질과의 상관관계는 일상생활활동 r=.293~.622, 우울증 -.804~-.533, 인지 기능 .090~.610, 수면의 질과 만족도는 각각 .107과 .367, 피로 -.260, 상지 기능 중 움직임의 질 .208, 사용 양 .364, 가족지지 .824, 통증 -.306, 재활 동기 .51~.86, 균형 .740, 자기효능감 .388로 분석되었다. 결론 : 뇌졸중 환자의 삶의 질은 다양한 요인에 의해 영향을 받으며, 환자의 삶의 질을 향상시키기 위해 작업치료사는 상지 기능과 일상생활동작뿐만 아니라 우울, 인지, 수면, 가족지지, 통증, 자기 효능감 등의 요인에 관심을 가질 필요가 있다.

• Molecular & Cellular Toxicology
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• 제4권4호
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• pp.355-359
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• 2008

This study aimed to determine the relationship between the C825T polymorphism in the G-protein ${\beta}$3-subunit (GNB3) gene and the response to citalopram in a Korean population with major depressive disorder (MDD). Citalopram was administered for 8 weeks to the 84 MDD patients who completed this study. All subjects were examined using the Structured Clinical Interview for DSM-IV, and the severity of depression was assessed using the 21-item Hamilton Depression Rating (HAMD-21) scale. A main effect of an interaction of genotype with time on the decrease in the HAMD-21 score during the 8-week study period was not found. ANOVA revealed no significant effects of the GNB3 C825T polymorphism on the decrease in the HAMD-21 score at each time period. Although the C825T polymorphism of the GNB3 gene may affect the pathogenesis of MDD, our results do not support the hypothesis that this polymorphism is involved in the therapeutic response to citalopram in Korean patients with MDD.

• 디지털융복합연구
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• 제14권11호
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• pp.513-526
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• 2016

본 연구의 목적은 군 병사들의 가족기능과 입대 전 인터넷중독수준을 알아보고, 이들의 입대 전 인터넷중독 수준이 군 생활부적응에 어떠한 영향을 미치는지, 또 이러한 영향 관계에서 가족기능의 매개적 역할을 파악하고자 함이다. 이를 위해서 현재 군 복무중인 병사 313명을 대상으로 설문조사를 실시하였고 구조방정식모형(structural equation model)을 통해 분석하였다. 연구 결과를 요약하면, 군 병사들의 입대 전 인터넷중독수준은 군 생활부적응에 직접 영향을 주고 있었으며, 특히 가족기능을 매개하여 군 생활부적응에 영향을 미치는 것으로 나타났다. 입대 전 인터넷중독수준은 가족기능을 통해서 군 생활부적응에 간접적 효과가 나타났고, 가족기능은 입대 전 인터넷중독 수준이 군생활 부적응에 영향을 주는 관계 속에서 부분 매개 효과를 가지는 것으로 확인되었다. 이 연구 결과를 바탕으로 향후 입대 전에 인터넷중독 경향이 있고 가족기능 수준이 낮은 병사들을 위하여 군과 가족을 포함한 융복합적인 차원에서 군 생활적응 프로그램 및 전문적 개입체계 구축의 필요성을 논의하였다.

• 대한간호학회지
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• 제4권2호
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• pp.144-158
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• 1974

This study was undertaken in an attempt to; 1) measure value orientation of nursing activities, 2) identify the relationship between nurse's role perception and patient's expectation, and 3) evaluate the pattern of nursing education and nursing service administration. 203 hospitalized adults and 203 professional nurses from 11 general hospitals in Seoul during the period of July to December 1973 were tested according to questionnaire based on 4 categories of clinical nursing activities, 1) physical care, 2) observation and control, 3) psycho-social care and 4) therapeutic measures. Results of the study are as follows: 1. Nurses were more concerned than patients in the physical care category. Significant difference was revealed by p<.01 level (t=2.800). Mean value score of nurses was average (2.84), and mean value score of patients was relative' y low (2.49). None of the physical care category questionnaire items were over 3.5. 2. Respondents from hospitals of total care system revealed significant difference in the physical care category by P〈.025 level. (t=2.242). Mean value score of both group were average level (nurse 2.90, patient 2.53), nurses showed higher concern. 3. Difference between nurse's role perception and patient's expectation in observation and control category was revealed non- significance by p〉0.05. level (t=1.238). Mean value score of both group revealed relatively high (nurse=3.44, patient 3.19). 4. Difference between nurse's role perception and patient〉expectation in psycho-social cart category revealed non- significance by p〉.05 level (t=0.758), Mean value score of both group revealed average level (nurse =2.71, patient =2.53), 5. Non- significant difference was noted between B. S. N. and diploma nurse's role perception in the psycho- social care category by p> 0.1 level (t=0.316). 4. Difference between nurse's role perception and patient's expectation in the rapeutic me assures category revealed non- significance by p〉0.05 level) t=0.503). Horses showed high concern by mean value score 3.56 level and patients relatively high by 3.41. All items of this category revealed very high or relatively high value score.

• Child Health Nursing Research
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• 제3권2호
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• pp.142-153
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• 1997

Empathy is an essential factor for establishing therapeutic relationship. Especially for pediatric nursing, the nurses need to know how to perceive children's feeling and thought and to express her understanding about them affectively. So, empathy is considered as an important concept in pediatric nursing. This study was attempted to measure the empathic ability of pediatric nurses by pediatric nurses and mothers of hospitalized children. The subject of this study consisted of 83 pediatric nurses and 106 mothers of hospitalized children in 4 hospitals in Seoul and 1 hospital in Kyung-Gi. Data were collected from Jan. 14 to Feb. 6, 1997, by the questionnair method. The instrument for this study was the Empathic Construct Rating Scale : ECRS(60-item, 5 point scale). Data were analyzed by descriptive statistics, t-test and ANOVA. Results of this study are summarized as follows 1. Pediatric nurses perceived their empathic ability to be moderately high (Mn=3.71). The level of perceived empathic ability of the pediatric nurses showed no significance by general characteristics. 2. The mothers of hospitalized children perceived nurses' empathic ability to be moderate(Mn=3.27). The level of perceived nurses' empathic ability of the mothers of hospitalized children showed significant differences by the experience of hospitalization of the children and the age of the mothers. 3. The perceived nurses' empathic ability of the mothers was significantly low than of the pediatric nurses(t=6.50, P<.001). From the above results, it can be concluded, that the empathic ability of the pediatric nurses is not sufficient for caring children and mothers of ficiently. So, the pediatric nurses' empathic ability is needed to improve through facilitative relationship training as refreshment in-service education program.

• 한국융합학회논문지
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• 제10권11호
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• pp.217-223
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• 2019

균형과 발목 근육 특성 (근력과 유연성) 사이의 관계는 낙상 위험의 증가에 대한 규명과 낙상방지 훈련프로그램을 발전시키기 위해서 중요할 것이다. 발목 근육 특성(근력과 유연성)과 균형사이의 관계는 이전에 연구되지 않았다. 이 연구의 목적은 발목근육특성과 균형사이의 관계를 평가하는 것이다. 16명의 건강한 참가자들이 본 연구에 자원하였다. 동적 균형은 와이-발란스 (Y-balance) 키트를 이용하여 측정하였다. 발목 근육 특성 (근력과 유연성)은 악력계와 고니어미터를 사용하여 측정하였다. 발목내번근력과 와이-발란스 (Y-balance) 측정 수행능력 사이에 양의 상관관계를 나타냈다. 임상가들은 동적균형의 발전을 위해서 치료적 중재를 하는 동안 발목 근력을 고려해야 한다.

• 대한불안의학회지
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• 제15권2호
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• pp.77-83
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• 2019

Objective : This study aims to investigate the relationship between negative sexual experience and psychiatric symptoms by gender and compare the effects of sexual assault and unwanted sexual experiences on psychiatric symptoms in patients with depression or anxiety disorders. Methods : A total of 204 respondents who have had negative sexual experiences of outpatients diagnosed with depression or anxiety disorders were evaluated with AUDIT, PSS, STAI, BDI, and SSI. Independent samples t-test was performed to compare the psychiatric symptom scale scores between male and female and identify the difference of the psychiatric symptom scale scores between those who have had sexual assault and those who have had only unwanted sexual experience. Results : There was no difference in psychiatric symptom scale scores except for AUDIT between male and female in 204 patients with negative sexual experience. There was also no significant difference in AUDIT, PSS, and STAI scores between those who experienced sexual assault and those who experienced only unwanted sexual experiences. BDI and SSI scores are significant higher in those who experienced sexual assault than those who experienced only unwanted sexual experiences. Conclusion : This suggests that male and female may have similar levels of psychiatric symptoms after experiencing negative sexual experiences. Psychiatric symptoms caused by sexual assault may have differences from the psychiatric symptoms caused by unwanted sexual experience. Understanding the differences in psychiatric symptoms according to the type of negative sexual experience may helpful to direct the therapeutic plans.

• 디지털융복합연구
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• 제17권1호
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• pp.443-447
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• 2019

방향성탄화수소 수용체(Arylhydrocarbon Receptor, AhR)은 리간드에 의해 활성화되어 체내 외래물질의 대사를 조절하는 전사인자다. 생체 내에서 AhR의 생리학적 역할은 오랜 기간 연구되어 왔으나 활성화를 유발하지 않는 길항제를 비롯하여 유효한 화학적 도구가 아직 개발되지 않아 기능 연구가 제한적이다. AhR이 다양한 질병의 발병기전에서 중요한 역할을 수행한다는 것이 보고됨에 따라 약물 표적으로서 유효하다고 판단되나 치료나 예방을 위한 유효한 약물은 아직 개발되지 않았다. 길항제로 알려진 화합물들은 낮은 농도에서는 활성이 있어 연구 목적으로 활용되고 있으나 높은 농도에서는 방향성 탄화수소를 활성화하는 부분적 agonist로 작용한다. 이에 AhR 활성화를 유도하지 않는 순수한 길항제의 개발이 필요하다. 본 연구에서는 이미 알려진 AhR 길항제의 골격인 phenyldiazenylphenylpicolinamide의 세 고리구조 중 두 고리구조에 존재하는 메틸 기들을 변형하여 활성을 평가하는 구조-활성 관계 연구를 통하여 새로운 길항제를 개발하고자 하였다.

• Child Health Nursing Research
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• 제25권2호
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• pp.184-195
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• 2019

Purpose: This study aimed to characterize the relationship between parental stress and nurses' communication as perceived by parents of high-risk newborns in a neonatal intensive care unit (NICU). Methods: The participants were 54 parents of high-risk newborns in a NICU. Data were collected from January to March 2018. Parental stress and parents' perceptions of nurses' communication ability and styles were measured using a questionnaire. Results: The average scores for parental stress and nurses' communication ability were 3.39 and 4.38 respectively, on a 5-point scale. Parents most commonly reported that nurses showed a friendly communication style, followed by informative and authoritative styles. Mothers and fathers reported significantly different levels of parental stress. Parental stress showed a negative correlation with nurses' perceived verbal communication ability. Higher scores for nurses' verbal communication ability and for friendly and informative communication styles were associated with lower parental stress induced by the environment, the baby's appearance and behaviors, and treatments in the NICU. Conclusion: The findings of this study suggest that nurses need to offer proper information for parents and to support parents by encouraging them to express their emotions of stress and by providing parents with therapeutic communication and opportunities to participate in care.

• Journal of Oral Medicine and Pain
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• 제46권1호
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• pp.1-8
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• 2021

Purpose: The purpose of this study was to assess the relationship between psychological factors and symptoms of oral mucosal diseases by means of the revised version of the Minnesota Multiphasic Personality Inventory (MMPI-2). Methods: Three hundred and eighteen college students in Gyeonggi-do completed the MMPI-2 and a questionnaire related to symptoms of oral mucosal diseases and collected data were analyzed by Student's t-test and one way ANOVA. Results: Subjects who have experienced herpetic stomatitis revealed significantly higher mean values of T-scores than subjects who have not on hypochondriasis (Hs) and hysteria (Hy) clinical scales of the MMPI-2 (p<0.05). In comparison with subjects who have had recurrent aphthous ulceration, subjects who have not had it manifested significantly higher elevations on the schizophrenia (Sc) clinical scale (p<0.05). Subjects who have suffered oral lichen planus (OLP) showed significantly higher mean values of T-scores than subjects who have not on paranoia (Pa) (p<0.05) and hypomania (Ma) (p<0.01) clinical scales. Mean values of T-scores on Ma clinical scale were significantly higher in subjects having experienced glossodynia than in subjects having not experienced (p<0.05). Subjects having felt taste disturbance exhibited significantly higher elevations on Hs (p<0.0001) and Hy (p<0.01) clinical scales compared to subjects having not. Conclusions: Symptoms of oral mucosal diseases such as herpetic stomatitis, taste disturbance, OLP, and glossodynia were found to be related to Hs, Hy, Pa, Ma clinical scales of the MMPI-2. Therefore, comprehensive psychological evaluations of those oral mucosal diseases may be beneficial in a therapeutic approach.